Abstract:
:Studies into the effects of ageing on language in adults with Down syndrome (DS) have tended to rely on measures that lack sensitivity to change because they fail to explore across linguistic domains or rely on proxy reports. The study aim was to use measures of receptive and expressive language from studies of younger individuals with DS in exploring relationships across linguistic and associated skills, and age in young to older adults. Fifty-five adults (aged 19-58 years), 10 with a diagnosis of or signs of early stage Alzheimer's Disease (AD), provided data on measures of functioning associated with AD, non-verbal cognition, receptive language (which provided a measure of mental age), receptive and expressive language, and short term auditory and visual memory. The first order correlation between the measure of AD and CA was significant; but not when the 10 participants with AD were removed from the analysis. Significant negative correlations were obtained between CA and all other measures; small to large significant positive correlations were found amongst the other measures. Partial correlations were conducted to remove the potential effects of AD and IQ (the latter measured by a test of non-verbal cognition). Remaining significant correlations were between auditory short term memory and all other included measures, expressive language and all other included measures, and CA and auditory short term memory and expressive language. The results indicate that deterioration with age in this cross-sectional study was accounted for largely by the presence of AD. The exceptions were for auditory short term memory and expressive language. The findings may reflect an underlying deficit in auditory short term memory for adults with DS, as has been found in previous research of children and adolescents. The implications are discussed in terms of the importance of including comprehensive measures of receptive and expressive language and the need to account for the presence of AD in studies of cognitive decline associated with ageing in DS.
journal_name
Res Dev Disabiljournal_title
Research in developmental disabilitiesauthors
Iacono T,Torr J,Wong HYdoi
10.1016/j.ridd.2009.12.009subject
Has Abstractpub_date
2010-03-01 00:00:00pages
568-76issue
2eissn
0891-4222issn
1873-3379pii
S0891-4222(09)00205-4journal_volume
31pub_type
杂志文章abstract:BACKGROUND:Like any child, children with Down syndrome (DS) affect the lives of their families. Most studies focus on the adaptation of parents and families of young children with DS, while relatively few studies include the perspective of fathers. AIMS:To determine 1) whether mothers and fathers of 11 to 13-year-olds...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2016.09.014
更新日期:2016-12-01 00:00:00
abstract::Stereotypic behavior is one of the more common disturbed behaviors displayed by people who are developmentally disabled. This study evaluated the indirect effects on stereotypic frequency when the value of a concurrent fixed-interval reinforcement schedule for adaptive behavior was varied. Three profoundly mentally re...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/0891-4222(88)90033-9
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To synthesize existing research evidence and examine effects of neuromuscular training on general strength, maximal strength, and functional mobility tasks in children and young adults with Down syndrome. METHODS:PubMed and EBSCO were used as a data source. To attain the aim of this study, literature search wa...
journal_title:Research in developmental disabilities
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ridd.2016.04.003
更新日期:2016-08-01 00:00:00
abstract::It is a widely accepted belief in clinical practice that children with a visual impairment can profit from the use of a low vision aid (LVA). However, we found a considerable gap in our scientific understanding of LVA use, particularly in young children. This is the reason for the analysis presented in this paper. A s...
journal_title:Research in developmental disabilities
pub_type: 杂志文章,评审
doi:10.1016/j.ridd.2011.01.027
更新日期:2011-05-01 00:00:00
abstract::This study explored self concepts in matched groups of adolescents and adults with Williams syndrome (WS) and Prader-Willi syndrome (PWS), using Damon and Hart's semi-structured interview. The main findings were that the WS participants were more productive in their responses to the interview, providing more self char...
journal_title:Research in developmental disabilities
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ridd.2003.05.003
更新日期:2004-03-01 00:00:00
abstract::To determine the accuracy of the published percentage body fat (%BF) prediction equations (Durnin et al., Johnston et al., Brook and Slaughter et al.) from skinfold thickness compared to air displacement plethysmography (ADP) in children and adolescents with Down syndrome (DS). Twenty-eight children and adolescents wi...
journal_title:Research in developmental disabilities
pub_type: 临床试验,杂志文章
doi:10.1016/j.ridd.2011.03.006
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Neurodevelopmental learning and attentional disorders (NLAD) such as dyslexia, dyscalculia and attention deficit hyperactivity disorder (ADHD) affect at least 6% of the adult population or more. They are associated with atypical cognitive patterns in early and adult life. The cognitive patterns of affected i...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2018.03.009
更新日期:2018-06-01 00:00:00
abstract::The aim of this paper is to review recent literature on health issues for adults with developmental disability and reflect on how this research informs service provision, future research work, and social and health policy. Studies based on mortality data are most likely to aim at identifying individuals most at risk o...
journal_title:Research in developmental disabilities
pub_type: 杂志文章,评审
doi:10.1016/s0891-4222(02)00143-9
更新日期:2002-11-01 00:00:00
abstract::Patterns of development of ToM-emotion abilities in intellectually disabled (ID) children and typically developing (TD) children matched on their developmental age were investigated. The links between cognition, language, social understanding and ToM-emotion abilities were examined. EDEI-R (Perron-Borelli, M. (1996). ...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2007.07.001
更新日期:2008-09-01 00:00:00
abstract::The literature on the association between behavioural and emotional problems and ageing in adults with Down syndrome (DS) without dementia is limited and has generally not reported on a wide range of behavioural and emotional problems. This research aimed to extend the field by examining the associations between age a...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.04.010
更新日期:2014-08-01 00:00:00
abstract::The main goal of the study was to map the difficulties and cognitive processes among adolescents (aged 13-21, N = 30) and adults (aged 25-66, N = 30) with mild and moderate intellectual disability (ID) when solving analogical problems. The participants were administered the Conceptual and Perceptual Analogical Modifia...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2010.10.010
更新日期:2011-01-01 00:00:00
abstract::Programmed training in identity matching to sample was given to six participants who had severe mental retardation, mental age-equivalent scores of 3.0 years or less, and histories of failures in prior assessments and training attempts with standard procedures. An intermediate goal of the training program was to estab...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/s0891-4222(98)00009-2
更新日期:1998-07-01 00:00:00
abstract::The present study sought to examine the longitudinal psychoeducational, neurocognitive, and psychiatric outcomes of children and adolescents with chromosome 22q11.2 deletion syndrome (22q11DS), a population with a high incidence of major psychiatric illnesses appearing in late adolescence/early adulthood. Little is kn...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.12.003
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Understanding how emotional faces are processed is important to help characterize the social deficits in Autism Spectrum Disorder (ASD). AIMS:We examined: (i) whether attention is modulated by emotional facial expression; (ii) the time course of the attentional preferences (short vs. long stimulus presentat...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2017.02.002
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Research shows that parents of children with autism spectrum disorder (ASD) are burdened with childcare responsibilities and at increased risk for elevated stress and poor family quality of life (FQOL). Little is known, however, about the dynamic interactions between mothers' and fathers' perceived parenting...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2020.103791
更新日期:2020-12-01 00:00:00
abstract::Processing speed deficits along with phonological awareness deficits have been identified as risk factors for dyslexia. This study was designed to examine the behavioral profiles of two groups, a younger (6-8 years) and an older (10-15 years) group of dyslexic children for the purposes of (1) evaluating the degree to ...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.06.002
更新日期:2013-09-01 00:00:00
abstract::Working with clients who show challenging behavior can be emotionally demanding and stressful for support staff, because this behavior may cause a range of negative emotional reactions and feelings. These reactions are of negative influence on staff wellbeing and behavior. Research has focused on negative emotions of ...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2013.08.027
更新日期:2013-11-01 00:00:00
abstract::Prader-Willi syndrome (PWS) is characterized by temper tantrums, impulsivity, mood fluctuations, difficulty with change in routine, skinpicking, stubbornness and aggression. Many studies on behavior in PWS are limited by sample size, age range, a lack of genetically confirmed diagnosis of PWS and inconsistent assessme...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2010.12.014
更新日期:2011-03-01 00:00:00
abstract::This study examined the effects of progressive relaxation training on the disruptive behaviors of a boy with autism. Moreover, his overt relaxed behaviors before and after relaxation training were measured using the Behavioral Relaxation Scale (Poppen, 1988, Poppen, 1998). After the participant received training in pr...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/s0891-4222(01)00083-x
更新日期:2001-11-01 00:00:00
abstract::This study evaluated whether two children with developmental disabilities would be able to improve their pointing performance through an Automatic Pointing Assistive Program (APAP) and a newly developed mouse driver (i.e. a new mouse driver replaces standard mouse driver, and is able to intercept mouse click action). ...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2009.04.003
更新日期:2009-11-01 00:00:00
abstract::Post-coma persons in an apparent condition of vegetative state and pervasive motor impairment pose serious problems in terms of assessment and intervention options. A technology-based learning assessment procedure might serve for them as a diagnostic supplement with possible implications for rehabilitation interventio...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2009.02.006
更新日期:2009-09-01 00:00:00
abstract::The aim of the functional magnetic resonance imaging (fMRI) study was to investigate brain activation associated with active and passive movements, and tactile stimulation in 17 children with right-sided unilateral cerebral palsy (CP), compared to 19 typically developing children (TD). The active movements consisted o...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.07.030
更新日期:2013-01-01 00:00:00
abstract::Children with autism spectrum disorder (ASD) often develop the word reading skills necessary to read text but struggle with reading comprehension. Comprehension skills are often under addressed in early elementary settings leaving children with ASD at a disadvantage once they are expected to read for meaning. This stu...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2019.103507
更新日期:2019-12-01 00:00:00
abstract::A questionnaire, the Verbal Behavior Assessment Scale, was developed to assess the communicative functions of individuals with developmental disabilities and severe mental handicap. To assess its psychometric characteristics, the questionnaire, comprising 15 items, was administered to pairs of caregivers of 115 partic...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/s0891-4222(99)00016-5
更新日期:1999-09-01 00:00:00
abstract::The present study assessed the use of a voice-detecting sensor interfaced with a scanning keyboard emulator to allow two boys with extensive motor disabilities to write. Specifically, the study (a) compared the effects of the voice-detecting sensor with those of a familiar pressure sensor on the boys' writing time, (b...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2008.03.001
更新日期:2009-03-01 00:00:00
abstract::In this study meaningful social stimuli were used as probes in a task requiring the judgment of semantic appropriateness to investigate contextual integration ability to test the ability of people with Williams syndrome (WS) to integrate information, as opposed to the use of meaningless syllables in audiovisual studie...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.03.049
更新日期:2014-07-01 00:00:00
abstract::The five to fifteen (FTF) is a parent questionnaire developed to assess ADHD, its common comorbid conditions and associated problems in children and adolescents. The present study examined (1) the psychometric properties of scores on the new teacher version of the FTF, (2) competing models of the FTF subdomain structu...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2014.12.018
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:22q11.2 deletion syndrome (22q) is a chromosome disorder, where a segment of chromosome 22, located at q11.2, is missing. This study aims to investigate the relationship between a number of parent-reported comorbid conditions including gastrointestinal symptoms, sleep problems, autism spectrum disorder (ASD)...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2020.103698
更新日期:2020-09-01 00:00:00
abstract::The cognitive profile of individuals with Down syndrome (DS) is known to be characterized by an impaired executive functioning, but inhibition-related processes have not been extensively examined in this setting. The aim of the present study was to investigate whether individuals with DS have any specific or general d...
journal_title:Research in developmental disabilities
pub_type: 杂志文章
doi:10.1016/j.ridd.2012.07.017
更新日期:2013-01-01 00:00:00
abstract::The purpose of this paper is to provide a brief review of current research in fragile X syndrome (FXS) with regards to the morphology and behavioral phenotype associated with FXS and the use of psychotropic medication for the treatment of behavior problems (e.g., aggression) often seen in FXS (full mutation). The lack...
journal_title:Research in developmental disabilities
pub_type: 杂志文章,评审
doi:10.1016/j.ridd.2006.09.001
更新日期:2007-11-01 00:00:00