Abstract：
:The purpose of this paper is to provide a brief review of current research in fragile X syndrome (FXS) with regards to the morphology and behavioral phenotype associated with FXS and the use of psychotropic medication for the treatment of behavior problems (e.g., aggression) often seen in FXS (full mutation). The lack of production of the fragile X mental retardation protein (FMRP) is associated with FXS and has been found to result in various neuronal changes such as altered dendritic morphology and function as well as altered neurotransmitter functions. A review of the basic literature on animal models and the relevance of these findings for the use of psychotropic treatment of problem behaviors in FXS will be discussed. Future research directions will be presented.
journal_name
Res Dev Disabiljournal_title
Research in developmental disabilitiesauthors
Valdovinos MGdoi
10.1016/j.ridd.2006.09.001subject
Has Abstractpub_date
2007-11-01 00:00:00pages
539-45issue
6eissn
0891-4222issn
1873-3379pii
S0891-4222(06)00082-5journal_volume
28pub_type
杂志文章,评审abstract：:To assess the factor validity and reliability for the Japanese version of the Aberrant Behavior Checklist-Community (ABC-Community), 322 subjects with moderate to profound mental retardation (188 males and 134 females, mean age 29.79 +/- 12.45) were rated by the staff at the residential facilities in Wakayama Prefectu...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/0891-4222(96)00015-7
更新日期：1996-07-01 00:00:00
abstract：:Children and adolescents with developmental disorders suffer from a wide range of psychopathology. However, there are no published studies examining this subject exclusively in this population using recent diagnostic criteria. The primary purpose of this paper is to report on the diagnosis encountered in a clinical se...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/s0891-4222(97)00016-4
更新日期：1997-09-01 00:00:00
abstract：:Research on adult typically-developing (TD) siblings of individuals with developmental disabilities remains limited, and outcomes for TD siblings appear to vary widely. For the current study, 82 adult TD siblings of individuals with autism spectrum disorder (ASD) or intellectual disability (ID) completed questionnaire...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2017.01.008
更新日期：2017-03-01 00:00:00
abstract：:The present study examined whether atypical visual processing is related to the level of social skills in children with autism spectrum disorder (ASD). Thirty-eight young children with ASD (29 boys, 9 girls) were included. Atypical visual processing was assessed by coding the number of lateral glances and the amount o...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.11.012
更新日期：2014-02-01 00:00:00
abstract：:Prior studies evaluating the response of developmentally disabled persons to relaxation training procedures are largely limited to case study reports. Most often relaxation training procedures are vaguely described in these studies, and limited outcome measures are employed. In the present comparative group outcome st...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/0891-4222(87)90040-0
更新日期：1987-01-01 00:00:00
abstract：:This study assessed the possibility of training three people with cognitive impairments using an augmented reality (AR)-based task prompting system. Using AR technology, the system provided picture cues, identified incorrect task steps on the fly, and helped users make corrections. Based on a multiple baseline design,...
journal_title：Research in developmental disabilities
pub_type： 临床试验,杂志文章
doi：10.1016/j.ridd.2013.06.026
更新日期：2013-10-01 00:00:00
abstract：:The present study sought to examine the longitudinal psychoeducational, neurocognitive, and psychiatric outcomes of children and adolescents with chromosome 22q11.2 deletion syndrome (22q11DS), a population with a high incidence of major psychiatric illnesses appearing in late adolescence/early adulthood. Little is kn...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2012.12.003
更新日期：2013-05-01 00:00:00
abstract：:The purpose of this study was to investigate the effect of five variations of imagery and physical practice on learning of Basketball free throws in adolescents with mental retardation (AWMR). Forty AWMR were randomly assigned to five groups and performed a variation of practice: physical practice, mental practice, ph...
journal_title：Research in developmental disabilities
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ridd.2009.07.022
更新日期：2010-01-01 00:00:00
abstract：:Sensory processing difficulties (SPD) are prevalent among children with ADHD. Yet, the question whether different SPD characterize children with different types of ADHD has not received enough attention in the literature. The current study characterized sensory processing difficulties (SPD) of children with different ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.01.008
更新日期：2011-05-01 00:00:00
abstract：:This study examined the relation between emergent literacy skills, teachers' reports of behavioral problems, and word reading achievement in a community sample of French students. Family background was investigated and included familial antecedents of reading difficulties (Fa/Rd) and parents' educational level. The an...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2012.11.029
更新日期：2013-03-01 00:00:00
abstract：:Facial expression processing and the attribution of facial emotions to a context were investigated in adults with Down syndrome (DS) in two experiments. Their performances were compared with those of a child control group matched for receptive vocabulary. The ability to process faces without emotional content was cont...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2009.02.004
更新日期：2009-09-01 00:00:00
abstract：:This study investigates how adults in two contrasting cultures (Italian and Japanese) perceive episodes of crying of typically developing (TD) children and children with Autism Disorder (AD). Although cries of children with AD have been reported to elicit more distress in Western cultures, it is not known whether simi...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2012.01.014
更新日期：2012-07-01 00:00:00
abstract：:Two students with developmental disabilities were taught to request six snack items. Requesting involved giving a graphic symbol to the trainer in exchange for the matching snack item. Following acquisition, we assessed the correspondence between requests and subsequent item selections by requiring the student to sele...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2005.12.002
更新日期：2007-01-01 00:00:00
abstract：:We identified factors associated with the empowerment of Japanese families using the Family Empowerment Scale (FES) to contribute to the improvement of empowerment in Japanese families raising a child with developmental disorders (DDs). The study was conducted in 350 caregivers who raised children aged 4-18 years with...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.01.037
更新日期：2011-05-01 00:00:00
abstract：:This paper documents the validation of a comprehensive scale designed to assess quality-of-life related personal outcomes for people with intellectual and developmental disabilities who receive support in social organizations. The INICO-FEAPS Scale was administered to 1627 people whose ages ranged between 16 and 72 ye...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2014.10.049
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Obesity is a health problem in China, but there are no reports on the obesity status of Chinese citizens with intellectual disabilities (ID). Research has shown that adults with ID have higher body mass index (BMI) than adults without ID, but this information is primarily based on populations resi...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2015.05.005
更新日期：2015-06-01 00:00:00
abstract：:The relationship between behavior problems and psychiatric disorders in individuals with intellectual disability is still unresolved. The present study compares the prevalence and pattern of psychiatric disorders in individuals with intellectual disability who were assessed on the ABC to have moderate and severe behav...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2007.06.002
更新日期：2008-07-01 00:00:00
abstract：:Dopamine active transporter gene (DAT1) is a candidate gene associated with attention-deficit/hyperactivity disorder (ADHD). The DAT1 variable number tandem repeat (VNTR)-3' polymorphism is functional and 9R carriers have been shown to produce more DAT than 10R homozygotes. We used functional magnetic resonance imagin...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2019.103430
更新日期：2019-09-01 00:00:00
abstract：:This study evaluated the use of the MacKinnon splint upon grasp skills in three children, ages 2 1/2 to 7 1/2, with spastic hemiplegia. The MacKinnon splint was sequentially introduced in a multiple baseline design across subjects. The results indicated improvement in each child's grasp of eight different, randomly pr...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/0891-4222(88)90048-0
更新日期：1988-01-01 00:00:00
abstract：:Children with developmental language disorders (DLD) often experience difficulty in understanding and engaging in interactive behavior with other children, which may lead to reduced daily physical activity and fitness levels. The present study evaluated the physical activity and physical fitness levels of 8-11 year ol...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2014.08.022
更新日期：2014-12-01 00:00:00
abstract：:People with Williams syndrome (WS) are said to have sociable and extremely trusting personalities, approaching strangers without hesitation. This study investigated whether people with WS are less likely than controls to attribute negative intent to others when interpreting a series of ambiguous pictures. This may, at...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.01.019
更新日期：2013-05-01 00:00:00
abstract：:This study aims to quantitatively characterize plantar pressure distribution in women affected by Ehlers-Danlos syndrome of the hypermobile type (EDS-HT) to verify the existence of peculiar patterns possibly related to postural anomalies or physical and functional lower limb impairments typical of this disease. A samp...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.07.040
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Angelman syndrome (AS) is a neurogenetic disorder characterized by intellectual disability, epilepsy, and low threshold for laughter. AIMS:We investigated the occurrence and severity of epilepsy and laughter-induced loss of postural muscle tone determined by the different genetic subtypes. METHODS:This stu...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2016.06.002
更新日期：2016-09-01 00:00:00
abstract：:Despite the growing attention being paid to teaching mathematics for students with disabilities, the existing research tends to focus on mathematical skill acquisition, but not on skill maintenance. The researchers in this study reviewed all studies from 1975 to 2018 that involved teaching mathematics to individuals w...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2020.103751
更新日期：2020-10-01 00:00:00
abstract：:Obesity is a worldwide health problem. Individuals with intellectual disabilities (ID) experience health disparities, including higher rates of obesity than their peers with typical development; however, there has been no tracking of the obesity rates of children and youth with ID over time. The objective of this stud...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.12.005
更新日期：2014-03-01 00:00:00
abstract：:Toys help children in mastering developmental tasks. This study investigated toy effect on children with developmental disabilities as they engage in using ordinary and adaptive toys. A single-subject design was used to identify the effects on their toy play abilities. Differences in toy effects between playing ordina...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2007.08.004
更新日期：2008-09-01 00:00:00
abstract：:We examined the internal consistency, test-retest reliability, and the responsiveness of the Bruininks-Oseretsky Test of Motor Proficiency-Second Edition (BOT-2) for children with intellectual disabilities (ID). One hundred children with ID aged 4-12 years tested on 3 separate occasions: two baseline measurements with...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2008.12.002
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Only a small number of longitudinal studies have been conducted to assess the literacy skills of children with hearing impairment. The results of these studies are inconsistent with regard to the importance of phonology in reading acquisition as is the case in studies with hearing children. Colin, Magnan, Ec...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.02.001
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Previous studies have shown that children with developmental coordination disorder (DCD) have a higher body fat and greater gait variability. Little research has investigated the gait muscle activity and lean mass measures in children with DCD. AIMS:To compare the leg muscle activation patterns of the gait ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2017.12.014
更新日期：2018-02-01 00:00:00
abstract：:The objectives of this study were to describe the nature of the attention deficits in children with Neurofibromatosis type 1 (NF1) in comparison with typically developing (TD) children, using the Virtual Classroom (VC), and to assess the utility of this instrument for detecting attention deficits. Twenty-nine NF1 chil...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.06.014
更新日期：2011-11-01 00:00:00
