Abstract:
BACKGROUND:Calcified coronary lesions have commonly been considered as a challenge for interventional cardiologists, and few previous studies of sirolimus-eluting stent (SES) for calcified lesion have been limited by small sample size. Therefore, we evaluated the effectiveness of SES implantation for the treatment of calcified lesions in a large Chinese cohort of real world practice. METHODS:A total of 956 consecutive patients who successfully received SES placement were enrolled in this study, and were divided into the two groups according to whether the mild-moderate calcified lesion treated with SES exists or not: noncalcified group (n = 637) and calcified group (n = 319). Lesions treated with SES were subjected to quantitative coronary angiography immediately and 8 months after stenting. RESULTS:Baseline characteristics including clinical, demographic or angiographic data were well balanced between the noncalcified and calcified groups. In the angiographic follow-up at 8 months, the in-stent restenosis and in-segment restenosis rates were similar in both the groups (in-stent restenosis: 3.8 vs. 4.0%, P>0.05; in-segment restenosis: 8.5 vs. 9.7%, P>0.05). The target lesion revascularization was not different between the two groups (5.2 vs. 6.8%; P>0.05). In addition, the in-stent late loss and overall thrombosis rate were also similar in both the groups (0.17+/-0.41 vs. 0.18+/-0.35 mm and 1.8 vs. 1.8%, P>0.05, respectively). CONCLUSION:Although stenting of the calcified lesion was hard, successful treatment with SES for mild-moderate calcified lesions was conferred to similar favorable results compared with noncalcified lesions in patients with coronary artery disease.
journal_name
Coron Artery Disjournal_title
Coronary artery diseaseauthors
Yuan JQ,Li JJ,Qin XW,Xu B,Yang YJ,Chen JL,Qiao SB,Ma WH,Yao M,Liu HB,Wu YJ,Chen J,You SJ,Dai J,Xia R,Gao RLdoi
10.1097/MCA.0b013e328330d5absubject
Has Abstractpub_date
2010-01-01 00:00:00pages
33-8issue
1eissn
0954-6928issn
1473-5830journal_volume
21pub_type
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
pub_type: 杂志文章
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
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journal_title:Coronary artery disease
pub_type: 杂志文章,评审
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journal_title:Coronary artery disease
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doi:10.1097/00019501-200412000-00006
更新日期:2004-12-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
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journal_title:Coronary artery disease
pub_type: 杂志文章
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journal_title:Coronary artery disease
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pub_type: 杂志文章,多中心研究
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更新日期:2016-08-01 00:00:00
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journal_title:Coronary artery disease
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更新日期:2009-05-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章
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更新日期:1995-07-01 00:00:00
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journal_title:Coronary artery disease
pub_type: 杂志文章,评审
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