The role of platelet inhibition in the drug-eluting stent era.

abstract：BACKGROUND:Cytomegalovirus (CMV), Chlamydia pneumoniae (C. pneumoniae), and Helicobacter pylori (H. pylori) have been implicated in atherosclerosis and restenosis after angioplasty. The patterns of distribution within coronary lesions and possible coinfections of these pathogens in the coronary vasculature had not prev...

journal_title：Coronary artery disease

authors： Radke PW,Merkelbach-Bruse S,Messmer BJ,vom Dahl J,Dörge H,Naami A,Vogel G,Handt S,Hanrath P

更新日期：2001-02-01 00:00:00

abstract：AIMS:Compare the degree of acute vascular injury caused by a polymer-free, thin-strut drug-eluting stent (DES) to that caused by a bioresorbable polymer, thick-strut DES using optical coherence tomography (OCT). METHODS AND RESULTS:Fifty patients requiring nonurgent PCI were randomized to receive either a thin or a th...

journal_title：Coronary artery disease

authors： Vilchez-Tschischke JP,Salazar C,Gil-Romero J,Mori R,Nuñez-Gil I,Quirós A,Nombela L,Del Trigo M,Jimenez-Quevedo P,Salinas P,Escaned J,Macaya C,Gonzalo N

更新日期：2020-08-19 00:00:00

abstract：BACKGROUND:The transradial approach has gained increasing popularity for elective percutaneous coronary intervention. However, the safety and feasibility of transradial coronary intervention (TRI) in acute myocardial infarction (AMI) remains uncertain. Hence, a meta-analysis of randomized trials was performed to compar...

journal_title：Coronary artery disease

authors： Singh PP,Singh M,Khosla N,Shah T,Molnar J,Arora R,Khosla S

更新日期：2012-06-01 00:00:00

abstract：:The Editor and Associate Editors are pleased that our readership will have the opportunity to benefit from a series of contributions by Dr John Rutherford addressing current issues in pharmacology and therapeutics pertinent to coronary artery disease. We are pleased also that Dr Rutherford will provide authoritative p...

journal_title：Coronary artery disease

authors： Rutherford JD

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Studies on the relationship between coronary artery calcium and aortic diameter are scarce. The aim of the current study was to evaluate the correlation between coronary artery calcium score (CACS) and maximal thoracic and abdominal aortic diameters in a population of elderly (>65 years) male hypertensive pa...

journal_title：Coronary artery disease

authors： Cho IJ,Heo R,Chang HJ,Shin S,Shim CY,Hong GR,Min JK,Chung N

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Elderly patients with ischaemic heart disease are often treated more conservatively and for longer than younger patients, but this strategy may result in subsequent invasive intervention of more advanced and higher risk coronary disease. METHODS:We performed a retrospective analysis of 109 patients aged > o...

journal_title：Coronary artery disease

authors： Vassilikos VP,Lim R,Kreidieh I,Nathan AW,Edmondson SJ,Rees GM,Banim SO,Dymond DS

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:P-selectin, an adhesion molecule of the selectin family, is expressed on the surface of activated thrombocytes by thrombin. The aim of the present study was to assess the predictive value of P-selectin (estimated by flow cytometric assay) for acute cardiac events in acute coronary syndrome. METHODS:The stud...

journal_title：Coronary artery disease

authors： Itoh T,Nakai K,Ono M,Hiramori K

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The 2015 American College of Cardiology/American Heart Association update on primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) recommended PCI of the non-infarct-related artery at the time of primary PCI (class IIb recommendation). Despite ev...

journal_title：Coronary artery disease

authors： Vaidya SR,Qamar A,Arora S,Devarapally SR,Kondur A,Kaul P

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:With new interventions minimizing ischemic myocardial injury, accurate and reliable techniques for the detection and continuous monitoring of myocardial ischemia are essential. We compared two techniques used for the detection of myocardial ischemia during coronary angioplasty: on-line computerized vectorcar...

journal_title：Coronary artery disease

authors： Jensen SM,Johansson G,Osterman G,Reiz S,Näslund U

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Carotid intima-media thickness (CIMT) is regarded as a controversial risk marker for cardiovascular disease (CVD). We aimed to evaluate the role of CIMT and carotid plaque progression as predictors for the progression of coronary plaque and compositions. METHODS:In the Garlic 4 study, asymptomatic patients ...

journal_title：Coronary artery disease

authors： Chao CJ,Lakshmanan S,Ceponiene I,Luo Y,Nakanishi R,Nezarat N,Kanisawa M,Budoff MJ

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Although coronary artery bypass graft surgery (CABG) has been proven to have mortality and morbidity benefits in patients with non-ST elevation myocardial infarction and multivessel disease, the appropriate timing of this procedure remains unclear. Therefore, we proposed a propensity score-matched analysis c...

journal_title：Coronary artery disease

authors： Ha LD,Ogunbayo G,Elbadawi A,Olorunfemi O,Messerli A

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Blunted heart rate variability (HRV) and presence of ventricular late potentials (VLPs) are known to correlate with an increased risk of ventricular tachycardia and sudden cardiac death in acute myocardial infarction (AMI). In the present study, we investigated the effect of glucose-insulin-potassium (GIK) s...

journal_title：Coronary artery disease

authors： Ulgen MS,Alan S,Akdemir O,Toprak N

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND AIM:The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter ...

journal_title：Coronary artery disease

authors： Nakanishi R,Post WS,Osawa K,Jayawardena E,Kim M,Sheidaee N,Nezarat N,Rahmani S,Kim N,Hathiramani N,Susarla S,Palella F,Witt M,Blaha MJ,Brown TT,Kingsley L,Haberlen SA,Dailing C,Budoff MJ

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to explore the individual effects of the CYP2C19 G681A polymorphism and omeprazole use and their interaction on clopidogrel responsiveness in acute coronary syndrome (ACS). The CYP2C19 G681A polymorphism and omeprazole use were both known for retarding the effects of clopidogrel unde...

journal_title：Coronary artery disease

authors： Jirungda S,Pussadhamma B,Komanasin N,Senthong V,Leuangwatthananon W

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The degree of coronary collateral development is not same in every patient with similar degree of coronary stenosis. In animal studies monocyte chemoattractant protein-1 (MCP-1) has been found to be related to collateral vessel development. In this study we investigated whether a higher serum MCP-1 level is ...

journal_title：Coronary artery disease

authors： Sahinarslan A,Kocaman SA,Topal S,Ercin U,Bukan N,Yalcin R,Timurkaynak T

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the association of widowhood with the severity and extent of coronary artery disease (CAD), and whether it is modified by sex or socioeconomic status. PATIENTS AND METHODS:A total of 1068 patients undergoing coronary angiography at five centers in Saudi Arabia and the Uni...

journal_title：Coronary artery disease

authors： Daoulah A,Alama MN,Elkhateeb OE,Al-Murayeh M,Al-Kaabi S,Al-Faifi SM,Alosaimi HM,Lotfi A,Asiri KS,Elimam AM,Abougalambo AS,Murad W,Haddara MM,Dixon CM,Alsheikh-Ali AA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:We sought to compare the long-term effectiveness and safety of triple antiplatelet therapy (TAPT) versus dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) for unprotected left main coronary artery disease (uLMCAD). BACKGROUND:An additional strategy to reduce recurrent ischemia ...

journal_title：Coronary artery disease

authors： Lee HJ,Yu CW,Hwang HK,Choi RK,Park JS,Li H,Ro YM

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Data on the comparative effectiveness of contemporary drug-eluting stents (DES) in the unrestricted, real-world setting are limited. We investigated the long-term effectiveness and safety of contemporary different drug-eluting stents by means of multiple treatment propensity score weighting. PATIENTS AND MET...

journal_title：Coronary artery disease

authors： Kwon O,Kang SH,Lee JB,Ahn JM,Lee CH,Kang DY,Lee PH,Kang SJ,Lee SW,Kim YH,Lee CW,Park SW,Park DW,Park SJ,IRIS-DES Registry Investigators.

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction is a key step in the initiation and progression of atherosclerosis and subsequent cardiovascular complications. We examined whether peripheral endothelial function, as assessed by fingertip reactive hyperemia-peripheral arterial tonometry (RH-PAT), can provide additional clinical valu...

journal_title：Coronary artery disease

authors： Matsuzawa Y,Li J,Aoki T,Guddeti RR,Kwon TG,Cilluffo R,Widmer RJ,Gulati R,Lennon RJ,Lerman LO,Lerman A

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) are the most common source of genetic variation. Although microvascular pathology is associated with cardiovascular events, genetic phenotypes causing microvascular disease remain largely unknown. This study identifies sex-specific SNPs associated with coronary microvas...

journal_title：Coronary artery disease

authors： Yoshino S,Cilluffo R,Best PJ,Atkinson EJ,Aoki T,Cunningham JM,de Andrade M,Choi BJ,Lerman LO,Lerman A

更新日期：2014-06-01 00:00:00

abstract：:The patient population with the need for oral anticoagulation to reduce stroke risk associated with atrial fibrillation (AF) and dual antiplatelet therapy to prevent stent thrombosis and myocardial infarction after percutaneous coronary intervention is increasing. However, patients treated with a triple therapy consis...

journal_title：Coronary artery disease

authors： Farhan S,Mehran R

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:This Perspective reviews the results of early and contemporary studies evaluating the safety and efficacy of coronary revascularization in patients with diabetes. It also addresses the implications of some of the data in the Bypass Angioplasty Revascularization Investigation in type 2 diabetes (BARI 2D) tria...

journal_title：Coronary artery disease

authors： Sobel BE

更新日期：2010-05-01 00:00:00

abstract：AIM:We evaluated the accuracy of multidetector computed tomography in detecting coronary artery disease and how it could change the indication to coronary angiography in patients with suspected cardiac chest pain. METHODS AND RESULTS:We enrolled 142 consecutive patients who had already performed an exercise electrocar...

journal_title：Coronary artery disease

authors： Pontone G,Andreini D,Ballerini G,Nobili E,Pepi M

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Erectile dysfunction and coronary artery disease share similar risk factors. Although phosphodiesterase-5 inhibitors used to treat erectile dysfunction do not adversely affect hemodynamic parameters in patients with coronary artery disease, their effects on myocardial blood flow are unknown. METHODS:In a ran...

journal_title：Coronary artery disease

authors： Weinsaft JW,Hickey K,Bokhari S,Shahzad A,Bedding A,Costigan TM,Warner MR,Emmick JT,Bergmann SR

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:YKL-40 is secreted by macrophages, including those in atherosclerotic plaques, neutrophils, and vascular smooth muscle cells. Circulating YKL-40 is elevated in patients with inflammation and increased tissue remodeling. The aim was to examine the sequential changes in serum YKL-40 in patients with acute myoc...

journal_title：Coronary artery disease

authors： Nøjgaard C,Høst NB,Christensen IJ,Poulsen SH,Egstrup K,Price PA,Johansen JS

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Ga-NOTA-RGD PET is a newly developed molecular imaging for angiogenesis. In this study, Ga-NOTA-RGD PET was used to investigate imaging characteristics in a rat myocardial infarction (MI) model and to monitor the efficacy of an angiogenesis induction therapy. MATERIALS AND METHODS:Ga-NOTA-RGD PET was perform...

journal_title：Coronary artery disease

authors： Eo JS,Paeng JC,Lee S,Lee YS,Jeong JM,Kang KW,Chung JK,Lee DS

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To report the final, cumulative, 5-year outcomes from the TAXUS ATLAS program, which studied the use of the TAXUS Liberté paclitaxel-eluting stent in de-novo coronary artery lesions. METHODS:TAXUS ATLAS Workhorse, Small Vessel, and Long Lesion are nonrandomized studies comparing TAXUS Liberté (N=871), TAXUS ...

journal_title：Coronary artery disease

authors： Ormiston JA,Charles O,Mann T,Hall JJ,McGarry T,Cannon LA,Webster MW,Mishkel GJ,Underwood PL,Dawkins KD

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Current and former smokers are at an increased risk for lung cancer and cardiovascular disease (CVD). We investigated two methods of visual scoring of coronary artery calcium on lung cancer screening computed tomography (CT) to predict cardiovascular and all-cause mortality. PARTICIPANTS AND METHODS:Cases we...

journal_title：Coronary artery disease

authors： Watts JR Jr,Sonavane SK,Snell-Bergeon J,Nath H

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The efficacy of thrombolytic therapy might be influenced by changes in the hemodynamic status. The aim of the study was to examine whether changes in perfusion pressure could affect the time to reflow in an in-vitro model. METHODS:The in-vitro flow system comprised flexible plastic tubes that enclosed a blo...

journal_title：Coronary artery disease

authors： Kornowski R,Mendelevich L,Zaretsky U,Einav S,Laniado S,Keren G

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The cause for discrepancy in the clinical presentation and outcome of coronary artery disease (CAD) between men and women is not established. Different prevalences of risk factors or specific sex-related atherosclerotic aspects have been advocated as possible explanations. We investigated coronary plaque mor...

journal_title：Coronary artery disease

authors： Mariani L,Burzotta F,Aurigemma C,Romano A,Niccoli G,Leone AM,Porto I,Trani C,Crea F

更新日期：2017-09-01 00:00:00