Analysis of individual patient data from clinical trials: epidural morphine for postoperative pain.

abstract：BACKGROUND:There have been few studies comparing the response to asphyxia and the effectiveness of typical cardiopulmonary resuscitation (CPR) using exogenous epinephrine administration and manual closed-chest compression between total intravenous anaesthesia (TIVA) and inhalational anaesthesia. METHODS:Twenty pigs we...

journal_title：British journal of anaesthesia

authors： Kurita T,Morita K,Kazama T,Sato S

更新日期：2003-12-01 00:00:00

abstract：:A randomized, double-blind study of 40 women was performed to compare patient controlled anaesthesia (PCA) morphine requirements after spinal anaesthesia for elective Caesarean section. The women received 0.2 mg of either morphine or diamorphine mixed with 0.5% bupivacaine in 8% dextrose. There were no significant dif...

journal_title：British journal of anaesthesia

authors： Husaini SW,Russell IF

更新日期：1998-08-01 00:00:00

abstract：:Three anaesthetic techniques based on isoflurane were compared in outpatients undergoing laparoscopy. Sixty healthy patients were randomly allocated to receive isoflurane via mask (spontaneous respiration), via tracheal tube (spontaneous respiration) or via tracheal tube with controlled ventilation. Moderate hypercarb...

journal_title：British journal of anaesthesia

authors： Kenefick JP,Leader A,Maltby JR,Taylor PJ

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Desflurane (DES)-induced preconditioning is mediated by large-conductance calcium-activated potassium channels (BK(Ca)). Whether BK(Ca) are involved in anaesthetic-induced post-conditioning is unknown. We tested the hypothesis that DES-induced post-conditioning is mediated by BK(Ca) upstream of the mitochond...

journal_title：British journal of anaesthesia

authors： Stumpner J,Lange M,Beck A,Smul TM,Lotz CA,Kehl F,Roewer N,Redel A

更新日期：2012-04-01 00:00:00

abstract：:The fresh gas flow rate necessary to prevent rebreathing in T-piece anaesthesia is well established at twice total ventilation. The minimum reservoir volume to avoid air dilution of anaesthetic gases in the alveolus at this flow rate is, however, undecided. A lung model was constructed to represent spontaneous respira...

journal_title：British journal of anaesthesia

authors： Naunton A

更新日期：1985-08-01 00:00:00

abstract：:We have evaluated the accuracy and reliability of the Paratrend 7 continuous blood-gas analyser in infants and small children under conditions of severe hypoxaemia admitted to the paediatric intensive care unit in the perioperative period with cyanotic congenital heart disease. PO2, PCO2 and pH (hydrogen ion concentra...

journal_title：British journal of anaesthesia

authors： Hatherill M,Tibby SM,Durward A,Rajah V,Murdoch IA

更新日期：1997-11-01 00:00:00

abstract：:We have examined the role of gamma-aminobutyric acid (GABA) neurones in propofol anaesthesia in mice using the righting reflex. Propofol i.p. increased the percentage of loss of the righting reflex in a dose-dependent manner with an ED50 value of 140 (95% confidence limits 123-160) mg kg-1 (n = 40; eight animals per d...

journal_title：British journal of anaesthesia

authors： Irifune M,Sugimura M,Takarada T,Maeoka K,Shimizu Y,Dohi T,Nishikawa T,Kawahara M

更新日期：1999-10-01 00:00:00

abstract：:We have used the technique of double-blind sequential allocation to quantify the minimum local analgesic concentration (MLAC) of extradural bupivacaine for women in early (median cervical dilatation 2 cm) and late (median cervical dilatation 5 cm) labour. The first bolus was 20 ml of the bupivacaine test solution. The...

journal_title：British journal of anaesthesia

authors： Capogna G,Celleno D,Lyons G,Columb M,Fusco P

更新日期：1998-01-01 00:00:00

abstract：:Critical narrowing of the dependent airways was examined in anaesthetized dogs with closed chests. Two techniques were used, (a) "closing" volume (CV), measured from the expired nitrogen plateau and (b) tantalum bronchography, to measure the calibre of airways of 3-8 mm diameter in the upper (UZ), middle (MZ) and lowe...

journal_title：British journal of anaesthesia

authors： Jones JG,Graf PD,Lemen R

更新日期：1978-08-01 00:00:00

abstract：:A patient with a tracheostomy and an iatrogenic tracheo-oesophageal fistula presented for diagnostic bronchoscopy and right upper lobectomy. The anaesthetic management is discussed with reference to the options available and, in particular, the use of a Brompton Pallister single lumen endobronchial tube. ...

journal_title：British journal of anaesthesia

authors： Buchanan CC,Vaughan RS,Verdi I

更新日期：1995-04-01 00:00:00

abstract：:"Priming" with alcuronium has been studied in 72 female patients. Blockade of single twitch responses of the adductor pollicis by alcuronium 0.15, 0.2 or 0.3 mg kg-1 could be accelerated by priming with a suitable priming portion of the total dose. Giving alcuronium 0.04 mg kg-1 30 s after the induction of anaesthesia...

journal_title：British journal of anaesthesia

authors： Black AM,Hutton P,el-Hassan KM,Morgan G,Clutton-Brock TH

更新日期：1986-08-01 00:00:00

abstract：:We have investigated the effect of volatile anaesthetics on protein synthesis and secretion in Hartley male guinea pig liver slices. The slices (250-300 microns thick) were incubated in sealed roller vials containing Krebs-Henseleit buffer at 37 degrees C under 95% oxygen. Volatile anaesthetics were vaporized in the v...

journal_title：British journal of anaesthesia

authors： Ghantous HN,Fernando JL,Keith RL,Gandolfi AJ,Brendel K

更新日期：1992-02-01 00:00:00

abstract：:Muscle fasciculations and pain following the administration of suxamethonium were assessed in a group of patients who performed a series of stretch exercises approximately 1 h before operation. Comparison was made with a group who received suxamethonium but no pretreatment. Fasciculations were significantly reduced in...

journal_title：British journal of anaesthesia

authors： Magee DA,Robinson RJ

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Midlatency auditory evoked potentials (MLAEP) are a promising tool for monitoring suppression of sensory processing during anaesthesia and might help to avoid awareness. MLAEP in children are different to those in adults and the exact changes during general anaesthesia are unknown. METHODS:In 49 children of...

journal_title：British journal of anaesthesia

authors： Daunderer M,Feuerecker MS,Scheller B,Pape NB,Schwender D,Kuhnle GE

更新日期：2007-12-01 00:00:00

abstract：:The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally painful orthopaedic hand surgery (trapeziectomy). Further investigations revealed a lifelong history...

journal_title：British journal of anaesthesia

authors： Habib AM,Okorokov AL,Hill MN,Bras JT,Lee MC,Li S,Gossage SJ,van Drimmelen M,Morena M,Houlden H,Ramirez JD,Bennett DLH,Srivastava D,Cox JJ

更新日期：2019-08-01 00:00:00

abstract：:The concentrations of volatile hydrocarbons were studied in breath samples from patients before and after anaesthesia. In patients to whom halothane was administered, there was a significant increase in the concentration of isobutene (from 0.43 +/- 0.09 to 4.66 +/- 2.22 nmol litre-1). There was no change in the concen...

journal_title：British journal of anaesthesia

authors： Hempel V,May R,Frank H,Remmer H,Köster U

更新日期：1980-10-01 00:00:00

abstract：:Bispectral index (BIS) was assessed as a monitor of depth of anaesthesia during fentanyl and midazolam anaesthesia for coronary bypass surgery. In 10 patients given morphine premedication, anaesthesia was induced with a combination of midazolam and fentanyl and thereafter maintained with a continuous infusion of a mix...

journal_title：British journal of anaesthesia

authors： Barr G,Anderson RE,Samuelsson S,Owall A,Jakobsson JG

更新日期：2000-06-01 00:00:00

abstract：:Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea and vomiting (IO...

journal_title：British journal of anaesthesia

authors： Mishriky BM,Habib AS

更新日期：2012-03-01 00:00:00

abstract：:A retrospective study was carried out to determine analgesic requirements in a group of orthopaedic outpatients (n = 145) and oral surgery inpatients (n = 172). The orthopaedic patients received a codeine-paracetamol premedication, an opioid during operation, or no analgesic. Less than 50% of the orthopaedic patients ...

journal_title：British journal of anaesthesia

authors： Campbell WI

更新日期：1990-05-01 00:00:00

abstract：:A recently installed anti-pollution system, initially designed to function in a passive mode, was evaluated, but found to be inconstant in its performance. A simple method of making the system active is described and evaluated. ...

journal_title：British journal of anaesthesia

authors： Asbury AJ,Hancox AJ

更新日期：1977-05-01 00:00:00

abstract：:We studied the elimination rate of nitrous oxide in 36 patients undergoing orthopaedic surgery. They were allocated randomly to one of six groups which differed in time of nitrous oxide exposure and mode of ventilation. In order to simulate recovery conditions, nitrous oxide administration was discontinued after 30, 6...

journal_title：British journal of anaesthesia

authors： Einarsson S,Stenqvist O,Bengtsson A,Houltz E,Bengtson JP

更新日期：1993-08-01 00:00:00

abstract：:We have examined dimethylthiourea, a potent scavenger of free radicals, for its anaesthetic properties in mice and rats. In mice, dimethylthiourea abolished the righting reflex at intraperitoneal doses greater than 1.5 mg g-1 bodyweight; in rats, it decreased the MAC value for isoflurane in a dose-dependent fashion. D...

journal_title：British journal of anaesthesia

authors： Koblin DD,Laster MJ,Liu J

更新日期：1993-04-01 00:00:00

abstract：:The effect on intervillous blood flow of lumbar extradural analgesia for Caesarean section was studied in nine healthy women using xenon-133. Extradural anaesthesia was performed with lignocaine 1 1/2% 16--20 ml with adrenaline 5 microgram ml-1. Impairment of placental blood flow during the block was observed in seven...

journal_title：British journal of anaesthesia

authors： Jouppila R,Jouppila P,Kuikka J,Hollmén A

更新日期：1978-03-01 00:00:00

abstract：:The analgesic effects of buprenorphine 2 microgram/kg--1 and 8 microgram. kg--1 were compared with those of pethidine 1 mg. kg--1 and pentazocine 0.6 mg.kg--1 in 172 patients recovering from surgery. The drugs were given by i.m. injection in the period immediately after operation and the quality of pain relief was ass...

journal_title：British journal of anaesthesia

authors： Hovell BC

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:None of the currently available hypnosis monitoring systems have evaluated balanced xenon anaesthesia. We investigated the performance of the bispectral index (BIS) and the composite A-line autoregressive index (cAAI) while comparing balanced xenon with sevoflurane anaesthesia. METHODS:Sixty patients underg...

journal_title：British journal of anaesthesia

authors： Fahlenkamp AV,Peters D,Biener IA,Billoet C,Apfel CC,Rossaint R,Coburn M

更新日期：2010-09-01 00:00:00

abstract：:Fast inactivation of sodium channel function is modified by anaesthetics. Its quantitative contribution to the overall anaesthetic effect is assessed by removing the fast inactivation mechanism enzymatically. Sodium channels from human brain cortex were incorporated into planar lipid bilayers. After incorporation, cha...

journal_title：British journal of anaesthesia

authors： Wartenberg HC,Urban BW,Duch DS

更新日期：1999-01-01 00:00:00

abstract：:We tested the hypothesis that the solvent for etomidate was a factor in the incidence of pain and other side effects after injection, and that these were associated with histamine release. Nine of 10 volunteers who received etomidate in a propylene glycol formulation reported moderate to severe pain on injection; only...

journal_title：British journal of anaesthesia

authors： Doenicke AW,Roizen MF,Hoernecke R,Lorenz W,Ostwald P

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:There is growing interest in the effect of postoperative analgesics on oncological outcomes after cancer surgery. We investigated the impact of tramadol after breast cancer surgery on recurrence and mortality and explored the mechanism by which tramadol affects cultured breast cancer cells in vitro. METHODS...

journal_title：British journal of anaesthesia

authors： Kim MH,Oh JE,Park S,Kim JH,Lee KY,Bai SJ,Song H,Hwang HJ,Kim DW,Yoo YC

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Ultrasound-guided internal jugular venous access increases the rate of successful cannulation and reduces the incidence of complications, compared with the landmark technique. Three transducer orientation approaches have been proposed for this procedure: short-axis (SAX), long-axis (LAX) and oblique-axis (OA...

journal_title：British journal of anaesthesia

authors： Batllori M,Urra M,Uriarte E,Romero C,Pueyo J,López-Olaondo L,Cambra K,Ibáñez B

更新日期：2016-03-01 00:00:00

abstract：:Five hundred and seventeen women in labour receiving extradural analgesia, using bupivacaine plain solution, were randomly allocated to one of three groups. Group A received 6-8ml of 0.5% solution, group B 10-14ml of 0.25% solution, and group C 6-8 ml of 0.25% solution. Spontaneous delivery occurred in 31.7% of patien...

journal_title：British journal of anaesthesia

authors： Thorburn J,Moir DD

更新日期：1981-09-01 00:00:00