Abstract:
:Simple surfactants achieve remarkable long-range order in aqueous environments. This organizing potential is seen most dramatically in biological membranes where phospholipid assemblies both define cell boundaries and provide a ubiquitous structural scaffold for controlling cellular chemistry. Here we consider simple peptides that also spontaneously assemble into exceptionally ordered scaffolds, and review early data suggesting that these structures maintain the functional diversity of proteins. We argue that such scaffolds can achieve the required molecular order and catalytic agility for the emergence of chemical evolution.
journal_name
Curr Opin Chem Bioljournal_title
Current opinion in chemical biologyauthors
Childers WS,Ni R,Mehta AK,Lynn DGdoi
10.1016/j.cbpa.2009.09.027subject
Has Abstractpub_date
2009-12-01 00:00:00pages
652-9issue
5-6eissn
1367-5931issn
1879-0402pii
S1367-5931(09)00144-6journal_volume
13pub_type
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