Physical examination of the potential tissue donor, what do European tissue banks do?

Abstract:

:According to the EU Directive 2006/17/EC, European tissue banks are required to perform a physical examination on every potential tissue donor. The directive itself, however, does not specify the content of this examination. The aim of this study was to investigate the current practice of physical examination in European tissue banks. A questionnaire was drawn up and sent to the members of the European Association of Tissue Banks and the European Eye Bank Association. Information was gathered on the type of procurement; the personnel involved (number, educational background and training); the content of physical examination; the problems encountered; and the outcome of the performed physical examinations. Completed questionnaires were received from 32 European tissue banks (response rate of 35%). Of these tissue banks, 73% perform a physical examination. The most frequently encountered problems are the inability to open the mouth due to rigor mortis, the inability to examine the total body surface and the incapacity to palpate the lymph nodes. Tissue banks reject potential donors, based on the results of the physical examination in 5% of cases (median rejection rate). Twenty-seven percent of the responding tissue banks do not perform a physical examination. This was most often due to a lack of adequate educational background and/or a lack of appropriate training.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Van Geyt C,Van Wijk M,Bokhorst A,Beele H

doi

10.1111/j.1399-0012.2009.01089.x

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

259-64

issue

2

eissn

0902-0063

issn

1399-0012

pii

CTR1089

journal_volume

24

pub_type

杂志文章
  • Changing the paradigm of organ utilization from PHS increased-risk donors: an opportunity whose time has come?

    abstract::Approximately 8-11% of all organ donors are classified by Public Health Service (PHS) as increased-risk. The proportion of PHS increased-risk donors is on the rise. At the University of Washington Medical Center, in 2014, the proportion of transplants from PHS increased-risk donors was 28% of liver transplants and 23%...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12582

    authors: Sibulesky L,Javed I,Reyes JD,Limaye AP

    更新日期:2015-09-01 00:00:00

  • Contrast-enhanced ultrasound of the transplant pancreas in the post-operative setting.

    abstract:BACKGROUND/OBJECTIVES:Vascular thrombosis is the most common cause of early graft loss after transplantation. Routine grayscale and Doppler ultrasound frequently fail to adequately visualize vascular compromise. Contrast-enhanced ultrasound is a novel approach to identifying these complications. METHODS:This was a pro...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13733

    authors: Swensson J,Nagaraju S,O'Brien D,Tann M,Shah A,Mangus R,Powelson J,Fridell J

    更新日期:2019-12-01 00:00:00

  • Renal transplant recipient attitudes toward steroid use and steroid withdrawal.

    abstract::Although steroid avoidance and withdrawal in renal transplant recipients (RTR) are actively being evaluated by physicians, the attitudes of recipients toward steroid use have not been systematically studied in the modern era. We conducted a confidential written survey of single-organ adult RTR pertaining to prednisone...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2003.00034.x

    authors: Prasad GV,Nash MM,McFarlane PA,Zaltzman JS

    更新日期:2003-04-01 00:00:00

  • Low birthweight and risk of albuminuria in living kidney donors.

    abstract::Low birthweight is linked to hypertension, chronic kidney disease and even end-stage renal disease. We hypothesized that living kidney donors born with lower birthweight may be at increased risk of hypertension, albuminuria, or reduced GFR beyond what is typical following uninephrectomy. Two hundred fifty-seven living...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12321

    authors: Berglund D,MacDonald D,Jackson S,Spong R,Issa N,Kukla A,Reule S,Weber M,Matas AJ,Ibrahim HN

    更新日期:2014-03-01 00:00:00

  • The effect of sirolimus on sex hormone levels of male renal transplant recipients.

    abstract:BACKGROUND:It is unclear whether sirolimus, a newer immunosuppressive agent, widely used in renal transplantation, affects male sex hormone levels or sexual function. METHODS:Sex hormone profiles in male renal transplant recipients were obtained and compared between a sirolimus-treated group and a group not on sirolim...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2005.00257.x

    authors: Lee S,Coco M,Greenstein SM,Schechner RS,Tellis VA,Glicklich DG

    更新日期:2005-04-01 00:00:00

  • Risk factors and outcome of stroke in renal transplant recipients.

    abstract::Stroke incidence is high in end-stage renal disease, and risk factors differ between the dialysis and general populations. However, risk factors and outcomes following renal transplantation remain unclear. We analyzed all adult patients with a functioning renal transplant from 01/01/2007 to 12/31/2012. Data were extra...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12765

    authors: Findlay MD,Thomson PC,MacIsaac R,Jardine AG,Patel RK,Stevens KK,Rutherford E,Clancy M,Geddes CC,Dawson J,Mark PB

    更新日期:2016-08-01 00:00:00

  • Interstitial alterations in renal cortex in acute tubular necrosis (ATN) post-renal transplantation and in patients with ATN not related to renal transplant.

    abstract:BACKGROUND:Abnormalities of renal function with long-term implications can persist after acute tubular necrosis (ATN), probably because of permanent loss of nephrons. Residual areas of fibrosis are also observed in the renal cortex post-ATN. In this study, we investigate the interstitial alterations post-ATN using hist...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1046/j.1399-0012.2003.00140.x

    authors: Moyses Neto M,Costa RS,Volpini RA,Garcia TM,Rodrigues FF,Coimbra TM

    更新日期:2004-04-01 00:00:00

  • Impact of venous drainage on regeneration of the anterior segment of right living-related liver grafts.

    abstract::The effect of additional venous reconstruction on morphologic and functional regeneration of the anterior segment of right-lobe liver grafts was compared among three groups according to graft type: right liver graft without the middle hepatic vein (MHV) or MHV tributaries (n=7), with MHV tributaries (n=25) and with th...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2006.00515.x

    authors: Mizuno S,Iida T,Yagi S,Usui M,Sakurai H,Isaji S,Uemoto S

    更新日期:2006-07-01 00:00:00

  • Characteristics, risks, and outcomes of post-transplant lymphoproliferative disease >3 years after pediatric heart transplant: A multicenter analysis.

    abstract::Post-transplant lymphoproliferative disorder (PTLD) is a significant complication after pediatric heart transplantation (HT), occurring in 5%-15% of patients within 3 years. Data >3 years from HT are limited. We sought to describe the prevalence, risk factors, and outcomes of PTLD occurring late (>3 years) after pedia...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ctr.13521

    authors: West SC,Friedland-Little JM,Schowengerdt KO Jr,Naftel DC,Pruitt Freeze E,Smith KS,Urschel S,Michaels MG,Kirklin JK,Feingold B

    更新日期:2019-05-01 00:00:00

  • Early changes in scores of chronic damage on transplant kidney protocol biopsies reflect donor characteristics, but not future graft function.

    abstract::The amount of irreversible injury on renal allograft biopsy predicts function, but little is known about the early evolution of this damage. In a single-center cohort, we examined the relationship between donor-, recipient-, and transplantation-associated factors and change in a morphometric index of chronic damage (I...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12251

    authors: Caplin B,Veighey K,Mahenderan A,Manook M,Henry J,Nitsch D,Harber M,Dupont P,Wheeler DC,Jones G,Fernando B,Howie AJ,Veitch P

    更新日期:2013-11-01 00:00:00

  • Serum globulin levels in predicting the extent of hepatic fibrosis in patients with recurrent post-transplant hepatitis C infection.

    abstract::The progression of HCV-related disease is particularly aggressive in the post-transplantation setting. Recipients with recurrent HCV infection undergo repeated liver biopsies in order to estimate disease progression. A strong association was found between serum immunoglobulins levels and hepatic fibrosis in non-transp...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2007.00657.x

    authors: Schmilovitz-Weiss H,Cohen M,Pappo O,Sulkes J,Braun M,Tur-Kaspa R,Ben-Ari Z

    更新日期:2007-05-01 00:00:00

  • Conversion to sirolimus-based maintenance immunosuppression using daclizumab bridge therapy in renal transplant recipients.

    abstract:INTRODUCTION:Conversion from calcineurin inhibitor (CI)-based maintenance immunosuppression to sirolimus (SRL)-based immunosuppression may be beneficial in selected renal transplant recipients. The purpose of this study was to evaluate the safety and efficacy of a daclizumab (DAC) bridge protocol in patients converted ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2004.00220.x

    authors: Sundberg AK,Rohr MS,Hartmann EL,Adams PL,Stratta RJ

    更新日期:2004-01-01 00:00:00

  • Prevalence of gastroparesis before and after lung transplantation and its association with lung allograft outcomes.

    abstract::The main cause of late morbidity and mortality after lung transplantation is bronchiolitis obliterans syndrome (BOS). This study assesses the prevalence of gastroparesis among lung-transplant recipients and its association with BOS. The files of 139 patients who underwent nuclear gastric emptying studies before and/or...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2011.01434.x

    authors: Raviv Y,D'Ovidio F,Pierre A,Chaparro C,Freeman M,Keshavjee S,Singer LG

    更新日期:2012-01-01 00:00:00

  • Hospital admissions and emergency department visits among kidney transplant recipients.

    abstract::Reducing acute care utilization is a means of improving long-term patient outcomes. We sought to assess high inpatient (IP) admission and standalone emergency department (ED) utilization within a 9-month period post-kidney transplantation and to identify mutable factors to reduce utilization. In this ten-year retrospe...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/ctr.13522

    authors: Weeda ER,Su Z,Taber DJ,Bian J,Morinelli TA,Pilch NA,Mauldin PD,DuBay DA

    更新日期:2019-05-01 00:00:00

  • The influence of CTLA-4 single nucleotide polymorphisms on acute kidney allograft rejection in Turkish patients.

    abstract::Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a cell surface protein, which down-regulates the immune response at CTLA-4/CD28/B7 pathway. We aimed to investigate the influence of the -318 C/T, +49 A/G, -1661 A/G and CT60A/G, and CTLA-4 gene polymorphisms on acute rejection of kidney allograft in Turkish patients. The s...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ctr.12563

    authors: Ruhi Ç,Sallakçi N,Yeğin O,Süleymanlar G,Ersoy FF

    更新日期:2015-07-01 00:00:00

  • Outcomes of antiviral treatment in hepatitis C virus liver transplant patients off immunosuppression in the direct acting antivirals era: A case series.

    abstract:BACKGROUND:Clearance of hepatitis C virus (HCV) under antiviral therapy, including direct-acting antivirals (DAAs), has been associated with higher risk of rejection. Whether patients who are not on immunosuppression (IS) during DAA therapy are at higher risk of rejection is unknown. METHODS:Four transplant recipients...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13303

    authors: Campos-Varela I,Agudelo EZ,Terrault NA

    更新日期:2018-07-01 00:00:00

  • Low infectious complications in segmental living related small bowel transplantation in adults.

    abstract::Clinical small bowel transplantation (SBTx) has been associated with a high rate of infectious complications. Laparotomy, preservation injury, abnormal motility, lymphatic disruption, aberrant systemic venous drainage, rejection and antibiotic therapy could all be implicated in the etiology of these complications. In ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2000.140609.x

    authors: Cicalese L,Sileri P,Asolati M,Rastellini C,Abcarian H,Benedetti E

    更新日期:2000-12-01 00:00:00

  • Post-transplant lymphoproliferative disorders: clinicopathological analysis of 43 cases in a single center, 1990-2009.

    abstract::Post-transplant lymphoproliferative disorders (PTLDs) are a heterogeneous set of complications of organ transplantation associated with poor patient prognosis. We analyzed the clinicopathological features of PTLDs in 43 adult and pediatric recipients of solid organ or bone marrow transplantation at a large transplant ...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-0012.2010.01392.x

    authors: Yoon SO,Yu E,Cho YM,Suh C,Kim KM,Han DJ,Lee SG,Huh J

    更新日期:2012-01-01 00:00:00

  • Impact of donor smoking history on post heart transplant outcomes: A propensity-matched analysis of ISHLT registry.

    abstract:PURPOSE:Smoking is a major public health issue, and its effect on cardiovascular outcomes is well established. This study evaluates the impact of donor smoking on heart transplant (HT) outcomes. METHODS:HT recipients between January 1, 2005, and December 31, 2016, with known donor smoking status were queried from the ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14127

    authors: Hussain Z,Yu M,Wozniak A,Kim D,Krepostman N,Liebo M,Raichlin E,Heroux A,Joyce C,Ilias-Basha H

    更新日期:2020-10-23 00:00:00

  • The profile of inflammatory and metabolic response in children undergoing heart transplantation.

    abstract::Inflammatory and metabolic response is an important factor to determine clinical outcomes. However, it remains unknown in children undergoing heart transplantation (HTx). We examined the perioperative changes in the inflammatory and metabolic response markers C-reactive protein (CRP) and prealbumin (PA) in 38 heart-tr...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2011.01566.x

    authors: Yu X,Larsen B,Urschel S,Cheung PY,Ross DB,Rebeyka I,West L,Li J

    更新日期:2012-03-01 00:00:00

  • A new approach to kidney wait-list management in the kidney allocation system era: Pilot implementation and evaluation.

    abstract::Kidney transplant wait-list management is becoming increasingly complex. We introduced a novel wait-list management strategy at our center, the Transplant Readiness Assessment Clinic (TRAC), whereby patients whose Kidney Allocation Scores surpass a threshold are actively managed. From January 1, 2016 through June 30, ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13406

    authors: Cheng XS,Busque S,Lee J,Discipulo K,Hartley C,Tulu Z,Scandling JD,Tan JC

    更新日期:2018-11-01 00:00:00

  • Primary endoluminal stenting of transplant renal artery stenosis from cadaver and non-heart-beating donor kidneys.

    abstract::This study evaluated the efficacy of primary endovascular stenting in cases of transplant renal artery stenosis (TRAS) from cadaver and non-heart-beating donor kidneys. Patients with TRAS (n = 13) from a single-centre transplant population (n = 476) were treated by primary percutaneous angioplasty and endovascular ste...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2006.00499.x

    authors: Ridgway D,White SA,Nixon M,Carr S,Blanchard K,Nicholson ML

    更新日期:2006-05-01 00:00:00

  • Successful transplantation of 50 single unit pediatric kidneys ages 11 to 48 months into adult recipients.

    abstract::There is currently an imbalance between the need for cadaveric kidneys for transplantation and the supply. The medical criteria for accepting cadaveric donors are changing and organs that were originally thought to be unacceptable have functioned well. Previous reports have discussed the problems with transplanting ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Jacoby K,Lippman HR,Hura CE,McFarlin L,Jones CF,Banowsky LH

    更新日期:1992-12-01 00:00:00

  • Influence of CYP3A5 and ABCB1 gene polymorphisms on calcineurin inhibitor-related neurotoxicity after hematopoietic stem cell transplantation.

    abstract:BACKGROUND:One severe side effect of calcineurin inhibitors (CNIs: such as cyclosporine [CsA] and tacrolimus [FK506]) is neurotoxicity. CNIs are substrates for CYP3A5 and P-glycoprotein (P-gp), encoded by ABCB1 gene. In the present study, we hypothesized that genetic variability in CYP3A5 and ABCB1 genes may be associa...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2009.01181.x

    authors: Yanagimachi M,Naruto T,Tanoshima R,Kato H,Yokosuka T,Kajiwara R,Fujii H,Tanaka F,Goto H,Yagihashi T,Kosaki K,Yokota S

    更新日期:2010-11-01 00:00:00

  • BK polyomavirus in solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.

    abstract::The present AST-IDCOP guidelines update information on BK polyomavirus (BKPyV) infection, replication, and disease, which impact kidney transplantation (KT), but rarely non-kidney solid organ transplantation (SOT). As pretransplant risk factors in KT donors and recipients presently do not translate into clinically val...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13528

    authors: Hirsch HH,Randhawa PS,AST Infectious Diseases Community of Practice.

    更新日期:2019-09-01 00:00:00

  • Depletion of natural antibodies in non-human primates--a step towards successful discordant xenografting in humans.

    abstract::There is evidence to suggest that long-term survival of discordant xenografts may be possible if the organ is transplanted at a time when the host natural anti-species (xenoreactive) antibodies are temporarily absent or otherwise inhibited from reacting with the donor antigens. There is also evidence that the target ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:

    authors: Cooper DK

    更新日期:1992-06-01 00:00:00

  • ALLOREACTIVE T LYMPHOCYTES CULTURED FROM LIVER TRANSPLANT BIOPSIES: ASSOCIATIONS OF HLA SPECIFICITY WITH CLINICOPATHOLOGICAL FINDINGS.

    abstract::Lymphocyte cultures grown from liver allograft biopsies were shown to exhibit alloreactivity towards donor cells as measured by primed lymphocyte testing (PLT). The PLT specificity was determined in assays using HLA typed panel cells and/or by inhibition testing with HLA specific monoclonal antibodies. Certain culture...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Markus BH,Demetris AJ,Saidman S,Fung JJ,Zeevi A,Starzl TE,Duquesnoy RJ

    更新日期:1988-01-01 00:00:00

  • A randomized trial of thymoglobulin vs. alemtuzumab (with lower dose maintenance immunosuppression) vs. daclizumab in renal transplantation at 24 months of follow-up.

    abstract:INTRODUCTION:A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported. METHODS:Ninety deceased donor (DD) first renal transplant recipients were randomized into three different antibody induction group...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1399-0012.2007.00774.x

    authors: Ciancio G,Burke GW,Gaynor JJ,Roth D,Kupin W,Rosen A,Cordovilla T,Tueros L,Herrada E,Miller J

    更新日期:2008-03-01 00:00:00

  • Uncontrolled deceased cardiac donation: An unutilized source for organ transplantation in the United States.

    abstract::The practice of uncontrolled donation after cardiac death (uDCD) has been met with tepid interest within the United States transplant community. Hesitancy stems largely from fears of eroding public trust due to complex ethical issues involving consent. Beyond ethical concerns, uDCD creates unique logistic challenges t...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/ctr.13474

    authors: Choudhury RA,Prins K,Moore HB,Yoeli D,Kam A,Nydam TL

    更新日期:2019-03-01 00:00:00

  • Efficacy of tonsillectomy for patients with recurrence of IgA nephropathy after kidney transplantation.

    abstract::From January 2007, we started to perform the tonsillectomy for every patient with recurrent IgA nephropathy (IgAN) after kidney transplantation. Up to September 2008, four recipients with primary IgAN had biopsy-proven recurrent IgAN. They had also progressive hematuria or proteinuria from on the average 14.3 months a...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2009.01003.x

    authors: Ushigome H,Suzuki T,Fujiki M,Nobori S,Sakamoto S,Okamoto M,Urasaki K,Yoshimura N

    更新日期:2009-08-01 00:00:00