Depletion of natural antibodies in non-human primates--a step towards successful discordant xenografting in humans.

abstract：:Tacrolimus (TAC) is a calcineurin inhibitor that is used for cardiac allograft rejection. Efficacy and safety data of a combined TAC/mycophenolate mofetil (MMF) therapy in comparison with a TAC/cortisone therapy in heart recipients are lacking. We analysed the clinical outcome of 41 patients who received TAC in combin...

journal_title：Clinical transplantation

authors： Fuchs U,Tenderich G,Zittermann A,Szabados F,Minami K,Koerfer R

更新日期：2006-07-01 00:00:00

abstract：:Renal transplantation was performed in a 24-yr-old woman with type AA systemic amyloidosis. Renal biopsy at 11 yr post-transplantation showed no amyloid recurrence, but the presence of mesangial proliferative glomerulonephritis and focal segmental glomerular sclerosis. Renal function was satisfactory with the exceptio...

journal_title：Clinical transplantation

authors： Nishikido M,Koga S,Kanetake H,Saito Y,Harada T,Taguchi T,Matsuya F,Shindo K

更新日期：1999-01-01 00:00:00

abstract：:A total of 123 consecutive patients with advanced-stage, acute leukemia undergoing HSCT from HLA-identical sibling donors were analyzed. A G-CSF-primed DLI was planned within day 60 post-transplantation before hematologic relapse was diagnosed. Fifty of the 123 individuals received prophylactic DLI, and 73 individuals...

journal_title：Clinical transplantation

authors： Wang Y,Liu DH,Fan ZP,Sun J,Wu XJ,Ma X,Xu LP,Liu KY,Liu QF,Wu DP,Huang XJ

更新日期：2012-07-01 00:00:00

abstract：:Evaluation of potential kidney transplant recipients is important to identify and treat conditions that may influence graft or patient survival after transplantation. We performed a single-center, observational cohort study to determine whether pretransplant midodrine use influences outcomes after kidney transplantati...

journal_title：Clinical transplantation

authors： Pottebaum AA,Hagopian JC,Brennan DC,Gharabagi A,Horwedel TA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder characterized by premature mortal cardiovascular complications. Liver transplantation (LT) is the only curative treatment option. In this study, the long-term clinical follow-up data of 8 patients who underwent LT with a diagnosis o...

journal_title：Clinical transplantation

authors： Gulsoy Kirnap N,Kirnap M,Bascil Tutuncu N,Moray G,Haberal M

更新日期：2019-12-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare histologic diagnosis in renal allografts. We report three cases with GIN. Case 1: a 37-yr-old woman received a kidney from her mother. On follow-up 15 months later, serum creatinine was increased and a graft biopsy showed epithelioid granuloma in the center of massi...

journal_title：Clinical transplantation

authors： Hotta K,Fukasawa Y,Sasaki H,Seki T,Togashi M,Harada H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:We performed a study to identify differences in the urinary microbiome associated with chronic allograft dysfunction (CAD) and compared the urinary microbiome of male and female transplant recipients with CAD. METHODS:This case-control study enrolled 67 patients within the Deterioration of Kidney Allograft ...

journal_title：Clinical transplantation

authors： Wu JF,Muthusamy A,Al-Ghalith GA,Knights D,Guo B,Wu B,Remmel RP,Schladt DP,Alegre ML,Oetting WS,Jacobson PA,Israni AK

更新日期：2018-12-01 00:00:00

abstract：:The concept of a narrow therapeutic window has guided the management of transplant recipients on cyclosporine immunosuppression since its inception more than a decade ago. The need to maintain immunosuppression and avoid toxicity imposed the requirement of monitoring cyclosporine levels within a limited range. The use...

journal_title：Clinical transplantation

authors： Takasugi M,Takasugi JK,Barba L

更新日期：1995-04-01 00:00:00

abstract：:The main cause of late morbidity and mortality after lung transplantation is bronchiolitis obliterans syndrome (BOS). This study assesses the prevalence of gastroparesis among lung-transplant recipients and its association with BOS. The files of 139 patients who underwent nuclear gastric emptying studies before and/or...

journal_title：Clinical transplantation

authors： Raviv Y,D'Ovidio F,Pierre A,Chaparro C,Freeman M,Keshavjee S,Singer LG

更新日期：2012-01-01 00:00:00

abstract：:Measurement of indocyanine green plasma disappearance rate (PDR(ICG)) has been suggested as a meaningful liver function parameter. However, there are only very limited data concerning its value in the monitoring of graft dysfunction (GDF) and primary non-function (PNF) especially during molecular absorbent recirculati...

journal_title：Clinical transplantation

authors： Scheingraber S,Richter S,Igna D,Girndt M,Flesch S,Kleinschmidt S,Schilling MK

更新日期：2007-11-01 00:00:00

abstract：:Flow cytometric assay (FCA) was used to detect a cytomegalovirus (CMV) specific antigen (pp65) in CMV-infected fibroblast cells and in leukocytes of kidney recipients. FCA distinguished clearly between the infected and non-infected fibroblast cells. Regarding transplant patients, the FCA was positive when the number o...

journal_title：Clinical transplantation

authors： Essa S,Pacsa AS,Al-Attiyah R,El-Shazly A,Raghupathy R,Said T

更新日期：2000-04-01 00:00:00

abstract：:The aim of this study was to identify indicators of outcome prior to transplantation in allogeneic hematopoietic stem cell transplantation (HCT). Clinical data of 106 patients with acute leukemia were retrospectively analyzed. We examined the role of pre-conditioning serum C-reactive protein (CRP) and ferritin levels,...

journal_title：Clinical transplantation

authors： Akı ŞZ,Suyanı E,Bildacı Y,Çakar MK,Baysal NA,Sucak GT

更新日期：2012-09-01 00:00:00

abstract：:The long-term side effects of lifelong steroid immunosuppression are well documented, therefore, steroid withdrawal (SW) if safe would clearly be of benefit. From 1987-1996, 470 kidney transplants were performed at our institution. During this time period, steroid withdrawal was offered to a select group of patients (...

journal_title：Clinical transplantation

authors： Sanfey H,Haussman G,Isaacs I,Ishitani M,Lobo P,McCullough C,Pruett T

更新日期：1997-10-01 00:00:00

abstract：:There is paucity in the data examining the differences in mycophenolate mofetil (MMF) dosing and outcomes among pediatric kidney transplant recipients (PKTX) between races. The aims of this study were as follows (i) to assess whether higher doses of MMF are being utilized in African American (AA) PKTX (ii) to determin...

journal_title：Clinical transplantation

authors： Jensen CJ,Shrivastava S,Taber DJ,Weimert NA,Shatat IF,Orak J,Chavin KD,Baliga PK

更新日期：2011-07-01 00:00:00

abstract：:The potential influence of racially or ethnically diverse cultural perspectives on patient compliance with post-transplant treatments is discussed. Domains of competency regarding culturally sensitive clinical practice are outlined to assist providers in better understanding the perspectives that may influence the vie...

journal_title：Clinical transplantation

authors： Prieto LR,Miller DS,Gayowski T,Marino IR

更新日期：1997-12-01 00:00:00

abstract：:A lack of research exploring post-transplant process optimization to reduce readmissions and increasing readmission rates at our center from 2009 to 2013 led to this study, aimed at assessing the effect of patient and process factors on 30-d readmission rates after kidney transplantation. This was a retrospective case...

journal_title：Clinical transplantation

authors： Covert KL,Fleming JN,Staino C,Casale JP,Boyle KM,Pilch NA,Meadows HB,Mardis CR,McGillicuddy JW,Nadig S,Bratton CF,Chavin KD,Baliga PK,Taber DJ

更新日期：2016-07-01 00:00:00

abstract：:Based on the results achieved in single human hand transplantations, we decided to perform the first double hand transplantation with a conventional immunosuppressive protocol in a patient with a high potential for functional recovery. Two years after transplantation the efficacy and the safety of this immunosuppressi...

journal_title：Clinical transplantation

authors： Petruzzo P,Revillard JP,Kanitakis J,Lanzetta M,Hakim NS,Lefrançois N,Owen E,Dubernard JM

更新日期：2003-10-01 00:00:00

abstract：:Steroid withdrawal has potential risks (rejection) and benefits (fewer complications). Most data on steroid-related complications predates cyclosporine (CsA). We tabulated the incidence of posttransplant complications considered to be steroid-related in 748 adult kidney transplant recipients (with at least 1 year of f...

journal_title：Clinical transplantation

authors： Fryer JP,Granger DK,Leventhal JR,Gillingham K,Najarian JS,Matas AJ

更新日期：1994-06-01 00:00:00

abstract：:Kidney outcomes in early post-liver transplantation (LT) are crucial for long-term prognosis, but difficult to predict. Among 203 adult LT patients, we studied the value of plasma neutrophil gelatinase-associated lipocalin (NGAL) measured pre-LT for predicting acute kidney injury (AKI), kidney-replacement therapy with...

journal_title：Clinical transplantation

authors： Aberg F,Lempinen M,Hollmén M,Nordin A,Mäkisalo H,Isoniemi H

更新日期：2014-08-01 00:00:00

abstract：:The effect of additional venous reconstruction on morphologic and functional regeneration of the anterior segment of right-lobe liver grafts was compared among three groups according to graft type: right liver graft without the middle hepatic vein (MHV) or MHV tributaries (n=7), with MHV tributaries (n=25) and with th...

journal_title：Clinical transplantation

authors： Mizuno S,Iida T,Yagi S,Usui M,Sakurai H,Isaji S,Uemoto S

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Relationships between race/ethnicity, recipient medical insurance, and living donor kidney transplantation (LKT) are incompletely described. METHODS:Associations between medical insurance and LKT were assessed in 447 recipients at a southeastern US transplant center. Primary and secondary payers were includ...

journal_title：Clinical transplantation

authors： Reeves-Daniel AM,Farney AC,Fletcher AJ,Assimos D,Westcott C,Rogers J,Stratta RJ,Rocco MV,Freedman BI

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. METHODS:A cross-sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosu...

journal_title：Clinical transplantation

authors： Chisholm-Burns MA,Spivey CA,Wilks SE

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION:Conversion from calcineurin inhibitor (CI)-based maintenance immunosuppression to sirolimus (SRL)-based immunosuppression may be beneficial in selected renal transplant recipients. The purpose of this study was to evaluate the safety and efficacy of a daclizumab (DAC) bridge protocol in patients converted ...

journal_title：Clinical transplantation

authors： Sundberg AK,Rohr MS,Hartmann EL,Adams PL,Stratta RJ

更新日期：2004-01-01 00:00:00

abstract：:Acute allograft glomerulopathy (AAG) characterized by hypercellularity, enlargement of endothelial cells, infiltration of glomeruli by mononuclear cells and webs of PAS-positive material has been reported as an unusual but distinct form of acute rejection in kidney transplant recipients. We present a case of persisten...

journal_title：Clinical transplantation

authors： Katafuchi R,Masutani K,Mizumasa T,Fujita E,Tanaka H,Ikeda K,Yanase T,Ando T,Fujimi S

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:There have been no published data on use of the the newer immunosuppressants tacrolimus and mycophenolate mofetil (MMF) in high immunological risk renal transplantation. We therefore undertook a prospective study to systematically assess outcomes using these agents as part of an aggressive immunosuppressive ...

journal_title：Clinical transplantation

authors： Zaltzman JS,Boucher A,Busque S,Halloran PF,Landsberg DN,McAlister VC,Russell D,Shoker A,Shapiro J,Tchervenkov JI,Ferguson R

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:The pediatric end stage liver disease (PELD) score has been used widely to prioritize children awaiting cadaveric liver transplantation (LTx). To establish the objective parameter for optimal timing of living-related LTx (LRLTx), we have assessed our cases using the PELD score. METHODS:From 1997 to 2002, 24...

journal_title：Clinical transplantation

authors： Kimura T,Hasegawa T,Sasaki T,Shimizu Y,Mushiake S,Fukuzawa M,Okada A

更新日期：2004-10-01 00:00:00

abstract：:Based on native CT scans of the pelvic region using a standardized calcification score, evaluation of iliac vascular calcification was performed between 2008 and 2012 prior to listing for renal transplantation in 205 patients with chronic kidney disease. Vascular calcification showed a decrease from proximal to distal...

journal_title：Clinical transplantation

authors： Kahn J,Ram LM,Eberhard K,Groselj-Strele A,Obermayer-Pietsch B,Müller H

更新日期：2017-03-01 00:00:00

abstract：:Micafungin has been approved for the prophylaxis of Candida infections in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we report a single-center experience of three different dose levels regarding efficacy, toxicity, and colonization with Candida ssp. in clinical practice. ...

journal_title：Clinical transplantation

authors： Langebrake C,Rohde H,Lellek H,Wolschke C,Kröger NM

更新日期：2014-03-01 00:00:00

abstract：:An exploratory, post hoc analysis was performed using data from a prospective, multicenter, open-label, randomized, two-period (14 d per period), two-sequence, crossover, steady-state pharmacokinetic study comparing generic tacrolimus (Sandoz) vs. reference tacrolimus in stable renal transplant patients receiving thei...

journal_title：Clinical transplantation

authors： Bloom RD,Trofe-Clark J,Wiland A,Alloway RR

更新日期：2013-11-01 00:00:00

abstract：:Cytomegalovirus (CMV) infection complicates the post-operative course of patients receiving solid organ transplants. While ganciclovir has significantly reduced the direct effects of CMV infection, some patients cannot tolerate the optimal therapeutic exposure required for CMV prevention and treatment. Few reports dir...

journal_title：Clinical transplantation

authors： Danziger-Isakov L,Mark Baillie G

更新日期：2009-06-01 00:00:00