Effect of dexmedetomidine, a selective and potent alpha 2-agonist, on cerebral blood flow and oxygen consumption during halothane anesthesia in dogs.

abstract：UNLABELLED:Reports of transient neurological symptoms with the use of subarachnoid lidocaine has generated interest in alternate local anesthetics of intermediate duration, such as mepivacaine. This prospective randomized, double-blinded, dose-response study examined the anesthetic and recovery profiles of 60- and 80-m...

journal_title：Anesthesia and analgesia

authors： Pawlowski J,Sukhani R,Pappas AL,Kim KM,Lurie J,Gunnerson H,Corsino A,Frey K,Tonino P

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Lung-protective ventilation (LPV) has been demonstrated to improve clinical outcomes in surgical patients. There are very limited data on the current use of LPV for patients undergoing 1-lung ventilation (1LV) despite evidence that 1LV may be a particularly important setting for its use. In this multicenter ...

journal_title：Anesthesia and analgesia

authors： Colquhoun DA,Naik BI,Durieux ME,Shanks AM,Kheterpal S,Bender SP,Blank RS,MPOG Investigators.

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Variations in the butyrylcholinesterase (BCHE) gene can prolong neuromuscular block after the administration of the neuromuscular blocking drugs succinylcholine and mivacurium. The most frequent variations in the BCHE gene are the atypical (A) and Kalow (K) variants. We, therefore, developed a detection appr...

journal_title：Anesthesia and analgesia

authors： Levano S,Keller D,Schobinger E,Urwyler A,Girard T

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD is associated with impaired int...

journal_title：Anesthesia and analgesia

authors： Goettel N,Burkhart CS,Rossi A,Cabella BC,Berres M,Monsch AU,Czosnyka M,Steiner LA

更新日期：2017-03-01 00:00:00

abstract：UNLABELLED:Inhaled nitric oxide (iNO) is superior to i.v. vasodilators for treatment of pulmonary hypertension (PH) after cardiac surgery, but iNO is a potentially toxic gas, and patient subsets who benefit from iNO are not yet clearly defined. We administered iNO 40 ppm, prostaglandin E1 (PGE1) 0.1 microg x kg(-1) min...

journal_title：Anesthesia and analgesia

authors： Schmid ER,Bürki C,Engel MH,Schmidlin D,Tornic M,Seifert B

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:In this prospective study, we compared the relationship between propofol concentrations and bispectral index (BIS) in children versus young adults anesthetized with target-controlled infusion (TCI) of propofol. METHODS:Forty-five prepubertal subjects (children) and 45 postpubertal subjects (adults) were stu...

journal_title：Anesthesia and analgesia

authors： Rigouzzo A,Girault L,Louvet N,Servin F,De-Smet T,Piat V,Seeman R,Murat I,Constant I

更新日期：2008-04-01 00:00:00

abstract：UNLABELLED:Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has psychotomimetic activity. NMDA receptor antagonists cause morphological damage in the posterior cingulate cortex, which may be the brain region responsible for their psychotomimetic effects. Benzodiazepines are effective in preve...

journal_title：Anesthesia and analgesia

authors： Nagata A,Nakao S,Miyamoto E,Inada T,Tooyama I,Kimura H,Shingu K

更新日期：1998-12-01 00:00:00

abstract：:Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injur...

journal_title：Anesthesia and analgesia

authors： van Caster P,Eiling S,Boekholt Y,Behmenburg F,Dorsch M,Heinen A,Hollmann MW,Huhn R

更新日期：2018-02-01 00:00:00

abstract：:A quest for a systems-level neuroscientific basis of anesthetic-induced loss and return of consciousness has been in the forefront of research for the past 2 decades. Recent advances toward the discovery of underlying mechanisms have been achieved using experimental electrophysiology, multichannel electroencephalograp...

journal_title：Anesthesia and analgesia

authors： Hudetz AG,Mashour GA

更新日期：2016-11-01 00:00:00

abstract：:Experimental aspiration pneumonitis studies in general have focused on the pathogenesis of the acidic component of the lung injury, although the injury produced by the particulate component of gastric contents largely has been ignored. The present study compares the inflammatory potential of small gastric particles to...

journal_title：Anesthesia and analgesia

authors： Knight PR,Rutter T,Tait AR,Coleman E,Johnson K

更新日期：1993-10-01 00:00:00

abstract：:A previous demonstration that the ratio of analgesic to anesthetic endpoints is not constant across inhalation anesthetic agents implies that more than one mechanism of action may be operant in general anesthesia. We hypothesized that the endogenous opiate systems might account for this observed disparity in ratios. T...

journal_title：Anesthesia and analgesia

authors： Levine LL,Winter PM,Nemoto EM,Uram M,Lin MR

更新日期：1986-04-01 00:00:00

abstract：:The fatal/anesthetic ratio (FAR) in 44 swine weighing 32.6 +/- 0.7 kg (SEM) was determined. Fatal anesthetic concentration (the numerator for FAR) was defined as the end-tidal concentration at which the pig lived at least 10 min, during experiments that involved step increments in anesthetic concentrations. Previously...

journal_title：Anesthesia and analgesia

authors： Roberts SL,Gilbert M,Tinker JH

更新日期：1987-06-01 00:00:00

abstract：:We previously reported that in rats with closed head trauma (CHT), intravenous (IV) administration of 0.25 mL/g of 5% dextrose solution (D5W) increased blood glucose (G), decreased blood sodium (Na), caused no change in blood osmolality (Osm), increased brain edema (BE), and worsened neurological severity score (NSS) ...

journal_title：Anesthesia and analgesia

authors： Gurevich B,Talmor D,Artru AA,Katcko L,Geva D,Gurman G,Shapira Y

更新日期：1997-03-01 00:00:00

abstract：:Transesophageal Doppler (TED) monitoring provides continuous, noninvasive monitoring of cardiac output by measurement of aortic flow velocities. Because of the effects on aortic flow dynamics resulting from atherosclerosis, aortic cross-clamping, and wide variations in arterial blood pressure, the validity of TED moni...

journal_title：Anesthesia and analgesia

authors： Perrino AC Jr,Fleming J,LaMantia KR

更新日期：1991-12-01 00:00:00

abstract：:The pandemic of heart failure and the limited options for treatment of end-stage disease have resulted in an increase in the utilization of left ventricular assist devices (LVADs). Improvements in device technology and patient survival have led to an expanding population of patients requiring noncardiac surgery while ...

journal_title：Anesthesia and analgesia

authors： Chung M

更新日期：2018-06-01 00:00:00

abstract：:We studied whether N-terminal pro brain natriuretic peptide (NT-pro BNP) measured at intensive care unit admission is an independent predictor of mortality in critically ill patients. We conducted a prospective observational cohort study enrolling 78 patients with APACHE II scores more than 12. Serum NT-pro BNP and ca...

journal_title：Anesthesia and analgesia

authors： Almog Y,Novack V,Megralishvili R,Kobal S,Barski L,King D,Zahger D

更新日期：2006-06-01 00:00:00

abstract：:We studied 60 children undergoing elective surgery to evaluate the effect of interactions between vecuronium and isoflurane or halothane on the potency and duration of neuromuscular blockade, as measured by electromyography. Vecuronium was first administered by a logarithm-based cumulative method (14, 22, 35, 56, 89 m...

journal_title：Anesthesia and analgesia

authors： Pittet JF,Melis A,Rouge JC,Morel DR,Gemperle G,Tassonyi E

更新日期：1990-03-01 00:00:00

abstract：UNLABELLED:Discitis (inflammation of the intervertebral disk) most commonly develops as a rare complication of bacterial infection or chemical or mechanical irritation during spine surgery (1) with a postoperative incidence of 1%-2.8% (2). It is also a complication of discography-the intradiscal injection of saline or ...

journal_title：Anesthesia and analgesia

authors： Bajwa ZH,Ho C,Grush A,Kleefield J,Warfield CA

更新日期：2002-02-01 00:00:00

abstract：:Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery. Fifty-six patients scheduled for coronary artery bypass grafting (CABG), were included in a randomized, double-blind study. The patients were anesthetized wit...

journal_title：Anesthesia and analgesia

authors： Sellevold OF,Berg EM,Levang OW

更新日期：1995-11-01 00:00:00

abstract：:We investigated the usefulness of peripheral flow index (PFI) measurement using a standard pulse oximetry digit probe for early prediction of successful regional blocks. Sixty-six patients scheduled for limb surgery underwent either axillary or sciatic block using a nerve stimulator technique with mepivacaine 1.5%. PF...

journal_title：Anesthesia and analgesia

authors： Galvin EM,Niehof S,Verbrugge SJ,Maissan I,Jahn A,Klein J,van Bommel J

更新日期：2006-07-01 00:00:00

abstract：:This study examined the changes in spinal and cortical evoked potentials (EPs) produced by fentanyl in the rabbit. The reversibility of these effects by naloxone and the effects of varying stimulus intensity also were examined. Eleven ketamine-anesthetized rabbits underwent analysis of spinal and cortical EPs produced...

journal_title：Anesthesia and analgesia

authors： Lee VC

更新日期：1994-02-01 00:00:00

abstract：:To further investigate possible prolongation of the frequency-corrected QT interval (QTc interval) after administration of droperidol (DRO), we studied 40 surgical patients who were randomly assigned to one of three groups, receiving an intravenous (IV) injection of either 0.1 mg/kg (Group 1, n = 10), 0.175 mg/kg (Gro...

journal_title：Anesthesia and analgesia

authors： Lischke V,Behne M,Doelken P,Schledt U,Probst S,Vettermann J

更新日期：1994-11-01 00:00:00

abstract：:To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane. After the injection of succinylcholine (0.3 mg/kg), cardiac arrhythmias occurred in al...

journal_title：Anesthesia and analgesia

authors： Leiman BC,Katz J,Butler BD

更新日期：1987-12-01 00:00:00

abstract：:In this study we attempted to define the minimal dosage of alfentanil (AF) needed in combination with nitrous oxide to provide satisfactory anesthetic conditions for lower abdominal gynecologic surgery. General anesthesia was induced in 12 women with AF (150 micrograms X kg-1) and 66% N2O in O2. An infusion of AF was ...

journal_title：Anesthesia and analgesia

authors： Ausems ME,Hug CC Jr,de Lange S

更新日期：1983-11-01 00:00:00

abstract：:Perioperative lung-protective ventilation (LPV) can reduce perioperative pulmonary morbidity. We hypothesized that modifying default anesthesia machine ventilator settings would increase the use of intraoperative LPV. Default tidal volume settings on our anesthesia machines were decreased from 600 to 400 mL, and defau...

journal_title：Anesthesia and analgesia

authors： Chiao SS,Colquhoun DA,Naik BI,Ma JZ,Nemergut EC,Durieux ME,Blank RS,Forkin KT

更新日期：2018-04-01 00:00:00

abstract：UNLABELLED:Endotracheal administration of epinephrine 0.02 mg/kg (twice the IV dose) is recommended when IV access is unavailable during cardiopulmonary resuscitation. The standard IV dose has been considered too small for the endotracheal route by causing a detrimental decrease of arterial blood pressure (BP), presuma...

journal_title：Anesthesia and analgesia

authors： Manisterski Y,Vaknin Z,Ben-Abraham R,Efrati O,Lotan D,Berkovitch M,Barak A,Barzilay Z,Paret G

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Intercostal nerve blocks with liposomal bupivacaine are commonly used for thoracic surgery pain management. However, dose scheduling is difficult because the pharmacokinetics of a single-dose intercostal injection of liposomal bupivacaine has never been investigated. The primary aim of this study was to asse...

journal_title：Anesthesia and analgesia

authors： Manson WC,Blank RS,Martin LW,Alpert SB,Dobrzanski TP,Schneider EB,Ratcliffe SJ,Durieux ME

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Hypothermia (HT) reduces neuronal injury after perinatal asphyxia. The anesthetic gas xenon (XE) may enhance this effect. We investigated the sedative and respiratory effects of variable XE concentrations at 37 degrees C normothermia (NT) or 32 degrees C HT after a hypoxic-ischemic (HI) insult to determine t...

journal_title：Anesthesia and analgesia

authors： Dingley J,Hobbs C,Ferguson J,Stone J,Thoresen M

更新日期：2008-03-01 00:00:00

abstract：UNLABELLED:Volatile anesthetics attenuate baroreflex function in a concentration-dependent manner. This study was designed to determine how long full recovery of baroreflex control of heart rate takes after isoflurane or sevoflurane anesthesia in healthy volunteers. We assessed baroreflex sensitivity in 20 subjects ran...

journal_title：Anesthesia and analgesia

authors： Nagasaki G,Tanaka M,Nishikawa T

更新日期：2001-11-01 00:00:00

abstract：:This consensus statement was commissioned in 2012 by the Board of Directors of the Society for Obstetric Anesthesia and Perinatology to improve maternal resuscitation by providing health care providers critical information (including point-of-care checklists) and operational strategies relevant to maternal cardiac arr...

journal_title：Anesthesia and analgesia

authors： Lipman S,Cohen S,Einav S,Jeejeebhoy F,Mhyre JM,Morrison LJ,Katz V,Tsen LC,Daniels K,Halamek LP,Suresh MS,Arafeh J,Gauthier D,Carvalho JC,Druzin M,Carvalho B,Society for Obstetric Anesthesia and Perinatology.

更新日期：2014-05-01 00:00:00