Mastocytosis: an unusual clonal disorder of bone marrow-derived hematopoietic progenitor cells.

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：:A population-based case-control study of college students was undertaken to estimate the effect of a positive clinical test for human papillomavirus (HPV) DNA (the Virapap test) on the rate of squamous intraepithelial lesions (SIL) of the uterine cervix. When age, multiple lifetime sexual partners, and oral contracept...

journal_title：American journal of clinical pathology

authors： Levine AJ,Harper J,Hilborne L,Rosenthal DL,Weismeier E,Haile RW

更新日期：1993-07-01 00:00:00

abstract：:To our knowledge, there are no universally accepted, evidence-based guidelines for how to resolve the HER2 status of tumors demonstrating equivocal amplification. The present study was based on 17 breast core biopsy specimens demonstrating invasive carcinoma with equivocal HER2 amplification, defined as an HER2/chromo...

journal_title：American journal of clinical pathology

authors： Striebel JM,Bhargava R,Horbinski C,Surti U,Dabbs DJ

更新日期：2008-03-01 00:00:00

abstract：:Our aim was to study the possible association between oral lichen planus and chronic hepatitis C in patients from the state of Minas Gerais, Brazil. Two groups of patients were studied: group 1, 50 patients with oral lichen planus evaluated for the presence of chronic hepatitis C; and group 2, 215 patients with chroni...

journal_title：American journal of clinical pathology

authors： de Mattos Camargo Grossmann S,de Aguiar MC,Teixeira R,do Carmo MA

更新日期：2007-05-01 00:00:00

abstract：:The authors quantified creatine kinase MB (CK-MB) isoenzyme activity and mass in the serum of 81 uremic and 20 nonuremic (control) patients who had no clinical or electrocardiographic evidence of acute myocardial infarction. CK-MB was quantified by three methods: electrophoresis, the QuiCK-MB (International Immunoassa...

journal_title：American journal of clinical pathology

authors： Medeiros LJ,Schotte D,Gerson B

更新日期：1987-01-01 00:00:00

abstract：:Factor V Leiden (FVR506Q) is a genetic defect in the factor V (FV) molecule that confers resistance to proteolysis by activated protein C (APC) and is the most common abnormality detected in patients studied for hereditary thrombophilia. The initial screening test for this abnormality was a comparison of the activated...

journal_title：American journal of clinical pathology

authors： Akhtar MS,Blair AJ,King TC,Sweeney JD

更新日期：1998-04-01 00:00:00

abstract：:Thrombocytopenia frequently complicates neonatal necrotizing enterocolitis (NEC) and has been postulated to result from absorption of bacterial endotoxins from the injured gut. The authors tested blood obtained during 47 episodes of NEC for endotoxin-like activity (ELA), using a Limulus amoebocyte lysate assay and fou...

journal_title：American journal of clinical pathology

authors： Scheifele DW,Olsen EM,Pendray MR

更新日期：1985-02-01 00:00:00

abstract：:Cytogenetic studies of bone marrow were performed in 230 consecutive cases of patients with chronic granulocytic leukemia (CGL) admitted to the National Cancer Institute since 1961. Twenty patients lacked the Philadelphia (Ph1) chromosome. All were previously untreated. When compared with Ph1-positive patients, CGL pa...

journal_title：American journal of clinical pathology

authors： Canellos GP,Whang-Peng J,DeVita VT

更新日期：1976-04-01 00:00:00

abstract：:Thirty-five consecutive renal biopsy specimens were evaluated by light histology using paraffin and glycol methacrylate embedding. The clarity of the renal structures was found to be much better, and the renal lesions better defined, using glycol methyacrylate embedding. ...

journal_title：American journal of clinical pathology

authors： Agodoa LC,Striker GE,Chi E

更新日期：1975-11-01 00:00:00

abstract：:A case of florid proliferative sialometaplasia arising in salivary ductal inclusions in an intraparotid lymph node is described. This lesion probably represents an exuberant response to sialadenitis. Other entities that enter into its differential diagnosis in this particular location are discussed. Except for Warthin...

journal_title：American journal of clinical pathology

authors： Goldman RL,Klein HZ

更新日期：1986-07-01 00:00:00

abstract：:Clotting tests based upon the activated partial thromboplastin time are disturbed by heparin. This brief communication shows that Factor XII clotting activity in plasma samples heparinized in vitro and in vivo can be measured accurately by means of an aPTT-test using congenitally deficient substrate plasma when the pl...

journal_title：American journal of clinical pathology

authors： Lämmle B,Tran TH,Duckert F

更新日期：1983-10-01 00:00:00

abstract：:The development of chemoresistance in a variety of cancers seems related to overexpression of the P-glycoprotein (P-gp) drug pump. Nephroblastoma, the most common malignant renal tumor of childhood, usually is responsive to treatment, and prognosis is favorable in most cases. However, the disease in a subset of patien...

journal_title：American journal of clinical pathology

authors： Camassei FD,Arancia G,Cianfriglia M,Bosman C,Francalanci P,Ravà L,Jenkner A,Donfrancesco A,Boldrini R

更新日期：2002-03-01 00:00:00

abstract：:A clinically and histopathologically well-documented case of malignant carcinoid tumor (with carcinoid syndrome) is described. The presence of numerous psammoma bodies in metastatic carcinoid tumor deposits, confirmed by histochemical and ultrastructural analyses, represents a heretofore unreported finding. ...

journal_title：American journal of clinical pathology

authors： Caya JG,Tieu TM,Wollenberg NJ,Soergel K,Anderson T

更新日期：1984-03-01 00:00:00

abstract：:Abbreviated pretransfusion testing, although permitted by American Association of Blood Banks Standards for unimmunized patients, is not widely practiced. Concerns remain about optimal antibody screening methods, antibodies missed by deleting the antiglobulin crossmatch, and cost-effectiveness. The authors prospective...

journal_title：American journal of clinical pathology

authors： Cordle DG,Strauss RG,Snyder EL,Floss AM

更新日期：1990-10-01 00:00:00

abstract：:Mechanical release of single cell suspensions from solid tumors for DNA analysis by flow cytometry has been shown to be optimal for adenocarcinomas in general. In the breast, many adenocarcinomas are fibrotic or scirrhous, creating difficulty in separating the neoplastic cells from the stroma. The authors have conduct...

journal_title：American journal of clinical pathology

authors： Torres FX,Mackowiak PG,Brown RD,Linden MD,Zarbo RJ

更新日期：1995-01-01 00:00:00

abstract：:Haemophilus influenzae type b, Escherichia coli, Neisseria meningitis, Streptococcus agalactiae, and Streptococcus pneumoniae are classically the predominant meningeal pathogens of children. The Directigen latex agglutination test identifies these pathogens by detecting specific antigens in cerebrospinal fluid (CSF) a...

journal_title：American journal of clinical pathology

authors： Hill RB,Adams S,Gunn BA,Eberly BJ

更新日期：1994-06-01 00:00:00

abstract：:Two patients with sporadic primary hyperparathyroidism were found to harbor tiny medullary thyroid carcinomas. In addition, parafollicular-cell hyperplasia was recognized in one of these thyroids by the use of immunoperoxidase stain to localize calcitonin. The possible relationships between these lesions are discussed...

journal_title：American journal of clinical pathology

authors： Livolsi VA,Feind CR

更新日期：1979-05-01 00:00:00

abstract：:Lesions of the breast containing extravasated mucin span a continuum from benign mucoceles to invasive mucinous (colloid) carcinoma. It is well known that distinguishing benign from malignant mucinous lesions is difficult infine-needle aspiration material. Whether these lesions also are difficult to distinguish in cor...

journal_title：American journal of clinical pathology

authors： Renshaw AA

更新日期：2002-07-01 00:00:00

abstract：:A flow cytometric technic was developed to detect platelet surface-bound immunoglobulin in patients with thrombocytopenia. Elevated platelet surface IgG and/or IgM was detected in 90.9% of patients with immune thrombocytopenia purpura (ITP). False positive results occurred in 9.3% of patients with nonimmune thrombocyt...

journal_title：American journal of clinical pathology

authors： Rosenfeld CS,Nichols G,Bodensteiner DC

更新日期：1987-04-01 00:00:00

abstract：:The Leu-8 antigen is found on the surface of many hematologic cells, including many T- and B-lymphocytes. With the use of a frozen-section immunoperoxidase technic, 152 B-cell non-Hodgkin's lymphomas were examined for Leu-8 expression. Of these lymphomas, 53% expressed Leu-8. Subclassification of the lymphomas with th...

journal_title：American journal of clinical pathology

authors： Michie SA,Garcia CF,Strickler JG,Dailey MO,Rouse RV,Warnke RA

更新日期：1987-10-01 00:00:00

abstract：:A case of metastatic squamous cell carcinoma to bone was studied using immunoperoxidase methods for Factor VIII-related antigen, producing positive staining in the tumor cells. Electron microscopy proved the squamous nature of the tumor, and, subsequently, a pulmonary primary tumor was found. Testing of additional tum...

journal_title：American journal of clinical pathology

authors： Wilson AJ

更新日期：1984-01-01 00:00:00

abstract：:The authors analyzed the frequency of immunophenotypic abnormalities in 1,474 cases of routinely fixed, paraffin-embedded B-lineage non-Hodgkin's lymphomas. B-lineage was determined by immunoreactivity for CD20 (L26, 92%); CD45RA (4KB5, an additional 3%) or immunoglobulin (Ig) light chain restriction (remaining 5%). C...

journal_title：American journal of clinical pathology

authors： Gelb AB,Rouse RV,Dorfman RF,Warnke RA

更新日期：1994-12-01 00:00:00

abstract：Objectives:Hemolyzed blood samples commonly occur in hospital emergency departments (EDs). Our objective was to determine whether replacing standard large-volume/high-vacuum sample tubes with low-volume/low-vacuum tubes would significantly affect ED hemolysis. Methods:This was a prospective intervention of the use of ...

journal_title：American journal of clinical pathology

authors： Phelan MP,Reineks EZ,Berriochoa JP,Schold JD,Hustey FM,Chamberlin J,Kovach A

更新日期：2017-10-01 00:00:00

abstract：:The cases of three patients who had clinical courses and hematologic data consistent with plasma-cell leukemia or a terminal leukemic phase of multiple myeloma are presented. A double Bence Jones protein was demonstrated in the urine of two of the patients. Immunoelectrophoresis and immunofluorescence studies demonstr...

journal_title：American journal of clinical pathology

authors： Pedraza MA

更新日期：1975-09-01 00:00:00

abstract：:Using microscopic screening criteria employed in the study of sputum in acute bacterial pneumonia, the authors evaluated 644 sputum samples from 347 patients submitted for mycobacterial bacterial culture. After microscopic examination, these specimens were processed using standard mycobacterial laboratory technics. Sa...

journal_title：American journal of clinical pathology

authors： Isaac-Renton JL,Puselja BB,Allen EA,Grzybowski S,Black WA

更新日期：1985-09-01 00:00:00

abstract：:Ewing family tumors (EFTs) and prostate carcinomas are characterized by rearrangement of ETS genes, most commonly FLI1 (EFTs) and ERG (prostate carcinomas). Previously, we characterized an antibody against ERG (EPR3864) for detecting ERG-rearranged prostate carcinoma. Because EPR3864 also cross-reacts with FLI1, we ev...

journal_title：American journal of clinical pathology

authors： Tomlins SA,Palanisamy N,Brenner JC,Stall JN,Siddiqui J,Thomas DG,Lucas DR,Chinnaiyan AM,Kunju LP

更新日期：2013-06-01 00:00:00

abstract：:Typical yeast-phase cells of Blastomyces dermatitidis have a characteristic appearance in tissue sections. Fungal morphologic variation occurs infrequently in the lesions of blastomycosis, yet it can complicate the differential diagnosis, particularly if fresh tissue is not available for microbiologic culture. The aut...

journal_title：American journal of clinical pathology

authors： Watts JC,Chandler FW,Mihalov ML,Kammeyer PL,Armin AR

更新日期：1990-04-01 00:00:00

abstract：:Sera from heparinized patients commonly display anodal slurring of both the alpha and beta lipoproteins when they are examined by high-resolution electrophoresis (HRE). In this study, the authors examined the effect of heparin and lipoprotein lipase on the electrophoretic migration of alpha and beta lipoproteins in se...

journal_title：American journal of clinical pathology

authors： Pearson JP,Keren DF

更新日期：1995-10-01 00:00:00

abstract：:Malignant mesothelioma is increasing in incidence worldwide, including in Japan. However, the accurate pathologic diagnosis of pleural or peritoneal mesothelioma (PM) is sometimes difficult if adequate histologic and immunohistochemical analyses are not undertaken. The aim of this study was to identify a useful antibo...

journal_title：American journal of clinical pathology

authors： Takeshima Y,Amatya VJ,Kushitani K,Inai K

更新日期：2008-11-01 00:00:00

abstract：:In 10 cases of Barrett adenocarcinoma, samples from 8 tumor areas (including superficial and deep from peripheral and central areas) and a regional lymph node metastasis were studied for amplification of c-myc, c-erbB-2, and EGFR. We analyzed loss of heterozygosity (LOH) at 3 loci (APC, MCC, and RB) and 2 anonymous mi...

journal_title：American journal of clinical pathology

authors： Owonikoko T,Rees M,Gabbert HE,Sarbia M

更新日期：2002-04-01 00:00:00