当前位置： SCI文献检索 > ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION期刊下所有文献 > Orthostatic responses to nitric oxide synthase inhibition in persons with tetraplegia.

Orthostatic responses to nitric oxide synthase inhibition in persons with tetraplegia.

Abstract：

OBJECTIVES:To determine the effects of 1.0 mg/kg nitro-L-arginine methyl ester (L-NAME) on orthostatic mean arterial pressure (MAP), serum aldosterone, and plasma renin concentrations in persons with chronic tetraplegia compared with nonspinal cord-injured controls. DESIGN:Prospective placebo-controlled intervention study. SETTING:James J. Peters Veterans Affairs Medical Center. PARTICIPANTS:Patients (n=5) with tetraplegia and controls (n=7) participated. The groups were matched for age, height, and weight; the average duration of injury in the tetraplegia group was 22+/-14 years. INTERVENTION:Subjects with tetraplegia visited the laboratory twice, receiving placebo on day 1 and L-NAME (1.0 mg/kg) on day 2. The agents were infused via an intravenous catheter over 60 minutes with the patient in the supine position. Data were collected during the infusion and then during head-up tilt to 45 degrees for 30 minutes. Control subjects visited the laboratory once for placebo infusion and the head-up tilt maneuver. MAIN OUTCOME MEASURE:Orthostatic MAP. RESULTS:Orthostatic MAP was reduced after placebo infusion in subjects with tetraplegia compared with controls (69+/-11 vs 89+/-9 mmHg, respectively; P<.01) and compared with L-NAME infusion (90+/-16 mmHg; P<.01). Orthostatic MAP did not differ when comparing the tetraplegia group with controls after L-NAME infusion. Orthostatic aldosterone levels were increased after placebo compared with L-NAME infusion in persons with tetraplegia; plasma renin levels did not differ among the groups. CONCLUSIONS:These data suggest that nitric oxide synthase inhibition may have clinical potential for treatment of orthostatic hypotension in persons with chronic tetraplegia.

journal_name

Arch Phys Med Rehabil

journal_title

Archives of physical medicine and rehabilitation

authors

Wecht JM,Radulovic M,Lafountaine MF,Rosado-Rivera D,Zhang RL,Bauman WA

doi

10.1016/j.apmr.2009.02.004

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

1428-34

issue

8

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(09)00281-0

journal_volume

90

pub_type

杂志文章

相关文献

ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION文献大全
  • Efficacy of forced-use therapy in hemiplegic cerebral palsy.

    abstract：OBJECTIVE:To determine the efficacy of forced-use therapy (FUT) on the improvement of upper-extremity function in children with hemiplegic cerebral palsy (CP). DESIGN:Prospective case series. SETTING:Outpatient ambulatory clinic in South Korea. PARTICIPANTS:Thirty-one patients with hemiplegic CP were assigned to the...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.apmr.2005.05.007

    authors： Sung IY,Ryu JS,Pyun SB,Yoo SD,Song WH,Park MJ

    更新日期：2005-11-01 00:00:00

  • Ego-syntonic alien hand syndrome after right posterior cerebral artery stroke.

    abstract：:The alien hand syndrome classically consists of involuntary movements accompanied by a feeling of foreignness and personification of the affected limb. Autocriticism, in which patients criticize and express astonished frustration with the behavior of the autonomous limb, is a commonly noted feature. Most cases of alie...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/s0003-9993(99)90114-4

    authors： Groom KN,Ng WK,Kevorkian CG,Levy JK

    更新日期：1999-02-01 00:00:00

  • Motor performance in children after traumatic brain injury.

    abstract：:Traumatic brain injury can result in persistent impairments of motor performance that interfere with functional activities. This study compared the gross and fine motor performance of 14 traumatically brain-injured children (five to 15 years old, with loss of consciousness for at least 24 hours) to 14 normal children ...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Chaplin D,Deitz J,Jaffe KM

    更新日期：1993-02-01 00:00:00

  • Inspiratory muscle training protocol using a pressure threshold device: effect on dyspnea in chronic obstructive pulmonary disease.

    abstract：OBJECTIVE:To evaluate the ability of patients with chronic obstructive pulmonary disease (COPD) to accomplish 6 weeks of inspiratory muscle training (IMT) using a pressure threshold device, and to observe how the training affected inspiratory muscle strength and dyspnea. DESIGN:Pilot study comparing baseline values wi...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/s0003-9993(99)90315-5

    authors： Nield MA

    更新日期：1999-01-01 00:00:00

  • Effect of durations of wheelchair tilt-in-space and recline on skin perfusion over the ischial tuberosity in people with spinal cord injury.

    abstract：OBJECTIVE:To compare the efficacy of various durations of wheelchair tilt-in-space and recline on enhancing skin perfusion over the ischial tuberosity in people with spinal cord injury (SCI). DESIGN:Repeated-measures, intervention and outcomes measure design. SETTING:University research laboratory. PARTICIPANTS:Powe...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.apmr.2012.11.019

    authors： Jan YK,Liao F,Jones MA,Rice LA,Tisdell T

    更新日期：2013-04-01 00:00:00

  • Executive functioning and predictors of falls in the rehabilitation setting.

    abstract：OBJECTIVE:To examine the incremental utility of executive function tests in the prediction of inpatient falls. DESIGN:Evaluation of neuropsychologic and medical risk factors for fall was completed at admission. Inpatient falls were tabulated following discharge. SETTING:A freestanding, urban rehabilitation hospital. ...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/s0003-9993(98)90035-1

    authors： Rapport LJ,Hanks RA,Millis SR,Deshpande SA

    更新日期：1998-06-01 00:00:00

  • Spinal cord injury rehabilitation. 4. Individual experience, personal adaptation, and social perspectives.

    abstract：:This learner-directed module highlights contemporary perspectives on personal success in the adjustment and adaptation of patients with spinal cord injury (SCI). It is the fourth in a series of five modules within the chapter on spinal cord injury rehabilitation in the Self-Directed Physiatric Education Program for pr...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,评审

    doi：10.1016/s0003-9993(97)90412-3

    authors： Stiens SA,Bergman SB,Formal CS

    更新日期：1997-03-01 00:00:00

  • Patient-focused rehabilitation team cohesiveness in veterans administration hospitals.

    abstract：OBJECTIVE:To quantify the relation of hospital culture, 3 levels of leadership (hospital-level administrators, discipline-specific supervisors, attending physician on the team), and physician involvement to patient-focused rehabilitation team cohesiveness. DESIGN:Survey research. SETTING:48 Veterans Administration ho...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,多中心研究

    doi：10.1016/s0003-9993(03)00197-7

    authors： Smits SJ,Falconer JA,Herrin J,Bowen SE,Strasser DC

    更新日期：2003-09-01 00:00:00

  • Fever in recently injured quadriplegic persons.

    abstract：:Two previously healthy adult patients with recent trauma to the cervical spinal cord and daily febrile episodes were evaluated extensively. No infectious or other cause for their fevers could be identified other than cervical spinal cord injury (SCI). Treatment with broad spectrum antibiotics, anticoagulation, and ces...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Sugarman B

    更新日期：1982-12-01 00:00:00

  • Isometric torque of the quadriceps femoris after concentric, eccentric and isometric training.

    abstract：:Twenty-seven normal, healthy women participated in this study, which investigated three methods of increasing the isometric strength of the quadriceps femoris through a six-week training program. Three experimental exercise groups were formed: A, eccentric, B, concentric, and C, isometric. The peak isometric torque of...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Pavone E,Moffat M

    更新日期：1985-03-01 00:00:00

  • Bladder volume determination: portable 3-D versus stationary 2-D ultrasound device.

    abstract：OBJECTIVE:To investigate how accurately a portable three-dimensional (3-D) scanner and a multipurpose two-dimensional (2-D) real-time scanner determined bladder volumes. STUDY DESIGN:Prospective, controlled clinical trial, single-blind, crossover design. SETTING AND PARTICIPANTS:Twenty-three inpatients with permanent...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0003-9993(00)90215-6

    authors： Schnider P,Birner P,Gendo A,Ratheiser K,Auff E

    更新日期：2000-01-01 00:00:00

  • Phenomenological study of neurogenic bowel from the perspective of individuals living with spinal cord injury.

    abstract：OBJECTIVE:To gain greater insight into the lived experience of individuals with spinal cord injury (SCI) and neurogenic bowel dysfunction (NBD). DESIGN:Qualitative (phenomenologic) interviews and analysis. SETTING:Community. PARTICIPANTS:Individuals with SCI and NBD (N=19) residing in the community. INTERVENTIONS:N...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2014.07.417

    authors： Burns AS,St-Germain D,Connolly M,Delparte JJ,Guindon A,Hitzig SL,Craven BC

    更新日期：2015-01-01 00:00:00

  • M-response quantification: a technique.

    abstract：:Median nerve responses in 13 patients and 9 normal subjects were evaluated using surface bipolar stimulation. The M response from surface electrodes placed upon the thenar eminence was recorded on a fiberoptic chart recorder and simultaneously subjected to true electronic integration. Comparison between the integrated...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Gans BM,Kraft GH

    更新日期：1981-08-01 00:00:00

  • Pelvic stabilization during resistance training: its effect on the development of lumbar extension strength.

    abstract：:The purpose of this study was to evaluate and compare resistance exercise training with and without pelvic stabilization on the development of isolated lumbar extension strength. Isometric torque of the isolated lumbar extensor muscles was measured at seven positions through a 72 degree range-of-motion on 47 men and 3...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Graves JE,Webb DC,Pollock ML,Matkozich J,Leggett SH,Carpenter DM,Foster DN,Cirulli J

    更新日期：1994-02-01 00:00:00

  • Psychosocial adjustment of post-poliomyelitis ventilator assisted individuals.

    abstract：:The effect of severe disability, tracheostomy, and ventilator use on psychosocial functioning, gainful employment, life satisfaction, and perceived well-being were studied for a population of 395 ventilator assisted post-poliomyelitis individuals (PVAIs). Standard psychosocial survey instruments and other general ques...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Bach JR,Campagnolo DI

    更新日期：1992-10-01 00:00:00

  • Behavioral assessment of unilateral neglect: study of the psychometric properties of the Catherine Bergego Scale.

    abstract：OBJECTIVE:To assess the psychometric properties of a scale for spatial neglect in everyday life. DESIGN:Validation study. SETTING:A neurologic rehabilitation unit in a university hospital. PARTICIPANTS:Eighty-three consecutive right-hemisphere stroke patients. INTERVENTIONS:Not applicable. MAIN OUTCOME MEASURES:Th...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1053/apmr.2003.50062

    authors： Azouvi P,Olivier S,de Montety G,Samuel C,Louis-Dreyfus A,Tesio L

    更新日期：2003-01-01 00:00:00

  • The Boston Rehabilitative Impairment Study of the Elderly: a description of methods.

    abstract：OBJECTIVES:To describe the methods of a longitudinal cohort study among older adults with preclinical disability. The study aims to address the lack of evidence guiding mobility rehabilitation for older adults by identifying those impairments and impairment combinations that are most responsible for mobility decline an...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2012.08.217

    authors： Holt NE,Percac-Lima S,Kurlinski LA,Thomas JC,Landry PM,Campbell B,Latham N,Ni P,Jette A,Leveille SG,Bean JF

    更新日期：2013-02-01 00:00:00

  • Performance-based outcomes of inpatient rehabilitation facilities treating hip fracture patients in the United States.

    abstract：OBJECTIVE:To examine the influence of facility and aggregate patient characteristics of inpatient rehabilitation facilities (IRFs) on performance-based rehabilitation outcomes in a national sample of IRFs treating Medicare beneficiaries with hip fracture. DESIGN:Secondary data analysis. SETTING:U.S. Medicare-certifie...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2015.01.003

    authors： Cary MP,Baernholdt M,Anderson RA,Merwin EI

    更新日期：2015-05-01 00:00:00

  • Evaluation of upper-limb spasticity after stroke: A clinical and neurophysiologic study.

    abstract：OBJECTIVES:To assess upper-limb spasticity after stroke by means of clinical and instrumental tools and to identify possible variables influencing the clinical pattern. DESIGN:Descriptive measurement study of a consecutive sample of patients with upper-limb spasticity after stroke. SETTING:Neurorehabilitation hospita...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2004.10.022

    authors： Pizzi A,Carlucci G,Falsini C,Verdesca S,Grippo A

    更新日期：2005-03-01 00:00:00

  • In-home virtual reality videogame telerehabilitation in adolescents with hemiplegic cerebral palsy.

    abstract：UNLABELLED:Golomb MR, McDonald BC, Warden SJ, Yonkman J, Saykin AJ, Shirley B, Huber M, Rabin B, AbdelBaky M, Nwosu ME, Barkat-Masih M, Burdea GC. In-home virtual reality videogame telerehabilitation in adolescents with hemiplegic cerebral palsy. OBJECTIVE:To investigate whether in-home remotely monitored virtual real...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2009.08.153

    authors： Golomb MR,McDonald BC,Warden SJ,Yonkman J,Saykin AJ,Shirley B,Huber M,Rabin B,Abdelbaky M,Nwosu ME,Barkat-Masih M,Burdea GC

    更新日期：2010-01-01 00:00:00

  • Ballroom dancing and cervical radiculopathy: a case report.

    abstract：:Dance injuries associated with cervical radiculopathy have not been described in the literature. This report describes the case of an international-style ballroom dancer who developed a cervical radiculopathy as a result of frequent lateral rotation and hyperextension of the cervical spine during dancing. The patient'...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/s0003-9993(98)90281-7

    authors： Tsung PA,Mulford GJ

    更新日期：1998-10-01 00:00:00

  • Intra-articular steroids in the treatment of rotator cuff tear: reappraisal by arthrography.

    abstract：:Previous studies have cast doubt on the efficacy of intra-articular steroids in the treatment of rotator cuff tears. This investigation re-evaluated the question, using shoulder arthrography both to substantiate the diagnosis of rotator cuff tear and to assure accurate intra-articular injection of steroid. Successful ...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Weiss JJ

    更新日期：1981-11-01 00:00:00

  • Pilot Study on the Effect of Ramelteon on Sleep Disturbance After Traumatic Brain Injury: Preliminary Evidence From a Clinical Trial.

    abstract：OBJECTIVE:To investigate the effect of ramelteon on sleep and daytime functioning among individuals with traumatic brain injury (TBI). DESIGN:A double-blind, placebo-controlled study with a crossover design. SETTING:A research facility attached to an acute rehabilitation hospital. PARTICIPANTS:Individuals with TBI (...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.apmr.2015.05.011

    authors： Lequerica A,Jasey N,Portelli Tremont JN,Chiaravalloti ND

    更新日期：2015-10-01 00:00:00

  • Multicenter Study of Sexual Functioning in Spouses/Partners of Persons With Traumatic Brain Injury.

    abstract：OBJECTIVE:To investigate sexual functioning and its predictors in spouses/partners of persons with traumatic brain injury (TBI). DESIGN:Inception cohort survey. SETTING:Community. PARTICIPANTS:Persons (N=70) with complicated mild to severe TBI admitted to 1 of 6 participating TBI Model Systems inpatient rehabilitati...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.apmr.2016.01.009

    authors： Sander AM,Maestas KL,Pappadis MR,Hammond FM,Hanks RA,NIDILRR Traumatic Brain Injury Model Systems Module Project on Sexuality After TBI.

    更新日期：2016-05-01 00:00:00

  • Exercise training using arms and legs versus legs along.

    abstract：:This study was undertaken to determine whether levels of conditioning associated with conventional leg work are comparable to those associated with both arm and leg work. Six healthy men conditioned for 6 weeks using both arms and legs while a similar group of 5 men conditioned using legs alone. The subjects trained 3...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Mostardi RA,Gandee RN,Norris WA

    更新日期：1981-07-01 00:00:00

  • Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group.

    abstract：:Recent advances in genomics, proteomics, and biotechnology have provided unprecedented opportunities for translational research and personalized medicine. Human biospecimens and biofluids represent an important resource from which molecular data can be generated to detect and classify injury and to identify molecular ...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章,评审

    doi：10.1016/j.apmr.2010.05.018

    authors： Manley GT,Diaz-Arrastia R,Brophy M,Engel D,Goodman C,Gwinn K,Veenstra TD,Ling G,Ottens AK,Tortella F,Hayes RL

    更新日期：2010-11-01 00:00:00

  • Lower extremity prosthetic mobility: a comparison of 3 self-report scales.

    abstract：OBJECTIVE:To assess and compare the reliability and validity of the Houghton Scale, the Prosthetic Profile of the Amputee Locomotor Capabilities Index (PPA-LCI), and the Prosthetic Evaluation Questionnaire (PEQ) mobility subscale, 3 disease-specific self-report measures of functional mobility for lower extremity prosth...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1053/apmr.2001.25987

    authors： Miller WC,Deathe AB,Speechley M

    更新日期：2001-10-01 00:00:00

  • Segmental H-reflex studies in upper and lower limbs of healthy subjects.

    abstract：:The H-reflex has been recorded from the flexor carpi radialis muscle in the upper limb and vastus medialis (quadriceps) muscle in the lower limb in relaxed healthy subjects. The characteristics of these reflexes have been compared with those of the soleus H-reflexes, recorded with the same technique, and similar behav...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：

    authors： Sabbahi MA,Khalil M

    更新日期：1990-03-01 00:00:00

  • Description of the moderate brain injured patient and predictors of discharge to rehabilitation.

    abstract：OBJECTIVE:To describe patients with moderate traumatic brain injury (TBI) treated and discharged at levels I and II trauma centers in the United States; and to describe the predictors of discharge to rehabilitation after acute care. DESIGN:Retrospective, cross-sectional, descriptive study. SETTING:Trauma centers. PA...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2014.09.018

    authors： Rogers S,Richards KC,Davidson M,Weinstein AA,Trickey AW

    更新日期：2015-02-01 00:00:00

  • Family functioning is associated with depressive symptoms in caregivers of acute stroke survivors.

    abstract：OBJECTIVE:To determine whether family functioning is uniquely associated with caregiver depressive symptoms in the immediate aftermath of stroke. DESIGN:Cross-sectional data from the baseline assessment of an intervention study for stroke survivors and their families. SETTING:Neurology inpatient service of a large ur...

    journal_title：Archives of physical medicine and rehabilitation

    pub_type： 杂志文章

    doi：10.1016/j.apmr.2008.12.014

    authors： Epstein-Lubow GP,Beevers CG,Bishop DS,Miller IW

    更新日期：2009-06-01 00:00:00