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The MMP2 gene may be associated with longissimus dorsi muscle area in the pig (Sus scrofa).

Abstract：

:The matrix metalloproteinase-2 gene (MMP2) was found to be associated with hip structure in pigs. Recently three quantitative trait loci (QTLs) for loin muscle area were found on chromosome 6, to which MMP2 was mapped. In the present study, association analyses were conducted in two pig populations for a single-nucleotide polymorphism (SNP) c.-1959C>G present at a putative promoter region of the MMP2 gene. The association results showed that the animals with the C allele have a significantly larger loin muscle area than that of the animals with the G allele (P < 0.05). To confirm the present results, further functional studies and an additional causative SNP discovery in pigs with various genetic backgrounds are necessary.

journal_name

J Appl Genet

journal_title

Journal of applied genetics

authors

Onteru SK,Fan B,Rothschild MF

doi

10.1007/BF03195679

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

251-2

issue

3

eissn

1234-1983

issn

2190-3883

pii

514

journal_volume

50

pub_type

杂志文章

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