Diastolic filling abnormality modified by left ventricular asynchrony in essential hypertension.

Abstract:

:Left ventricular (LV) asynchrony has been demonstrated to result in diastolic dysfunction. To test the hypothesis that altered LV synchrony interferes with LV diastolic function in essential hypertensive patients (HT), we performed radionuclide ventriculography and echocardiography in 38 HT and 11 normotensive subjects. LV diastolic asynchrony was measured as the sum (total delta t) of the absolute values of the time difference between global peak filling rate (PFR) and regional PFR. Global PFR and time to PFR were significantly reduced in HT. Although total delta t did not differ between two groups, total delta t significantly correlated with PFR (r = -0.44, p less than 0.01) in HT. Moreover, total delta t positively related to LV endsystolic stress and inversely related to LV ejection fraction in HT. Thus, LV asynchrony, in part, plays a role in early diastolic filling abnormality in hypertensive patients.

journal_name

Acta Cardiol

journal_title

Acta cardiologica

authors

Nii T,Nakashima Y,Ikeda M,Arakawa K

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

471-7

issue

4

eissn

0001-5385

issn

1784-973X

journal_volume

46

pub_type

杂志文章
  • The quest for indicators of paroxysmal atrial fibrillation in sinus rhythm - the DETECT AF trial.

    abstract::Background: Atrial fibrillation (AF) is related to an increased stroke risk. At present, differentiation between patients with paroxysmal AF (pAF) and without is only possible during AF episodes and not during sinus rhythm. If AF could be diagnosed more quickly and reliably, anticoagulation therapy may be administered...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2018.1493248

    authors: Brasier N,Engelter S,Kolbitsch T,Tabord A,Knobeloch J,Kühne M,Conen D,Traenka C,Kreutzberger T,Völlmin G,Eckstein J

    更新日期:2019-08-01 00:00:00

  • Oxidized LDL and coronary heart disease.

    abstract::During inflammation, several cell types synthesize and secrete phospholipase A2 that catalyses lipid oxidation in LDL. Myeloperoxidase, a haeme protein secreted by activated phagocytes, oxidizes L-tyrosine to a tyrosyl radical that is a physiological catalyst for the initiation of lipid oxidation in LDL. Lipid oxidati...

    journal_title:Acta cardiologica

    pub_type: 杂志文章,评审

    doi:10.2143/AC.59.5.2005219

    authors: Holvoet P

    更新日期:2004-10-01 00:00:00

  • Coronary sinus signal amplitude predicts left atrial scarring.

    abstract:BACKGROUND:Left atrial scarring is recognised as a critical component in the maintenance of atrial fibrillation and is associated with the failure of interventional treatment. Diminished bipolar voltage (LV) has been proposed as a useful tool for left atrial scar quantification. We hypothesised that, due to its anatomi...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2017.1420438

    authors: Attanasio P,Qaiyumi D,Röhle R,Wutzler A,Safak E,Muntean B,Boldt LH,Pieske B,Haverkamp W,Huemer M

    更新日期:2017-12-22 00:00:00

  • Survival and heart failure therapy in chronic dialysis patients with heart failure and reduced left ventricular ejection fraction: an observational retrospective study.

    abstract:AIMS:We retrospectively followed 250 patients who started dialysis between 2005 and 2009 to clarify the prevalence, the prognosis and the prescribed heart failure treatment of systolic heart failure patients on dialysis. METHODS AND RESULTS:This cohort was divided according to left ventricular ejection fraction (LVEF)...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.68.1.2959632

    authors: Derthoo D,Belmans A,Claes K,Bammens B,Ciarka A,Droogné W,Vanhaecke J,Van Cleemput J,Janssens S

    更新日期:2013-02-01 00:00:00

  • Relation between coronary artery calcium score and serum tenascin-C level in patients without known coronary artery disease.

    abstract:OBJECTIVE:Presence of coronary artery disease (CAD) also in subjects without traditional risk factors leads to a search for new risk factors. Tenascin-C (TNC), an extracellular matrix glycoprotein is normally found in very low concentrations in tissues and serum of adults, whereas its expression is enhanced in case of ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.70.6.3120174

    authors: Ozmen Yildiz P,Yildiz I,Ozmen C,Karabacak M,Doven O

    更新日期:2015-12-01 00:00:00

  • Combined "pro-atherosclerotic" variants of the ACE and APOE genes increase the risk of the coronary artery disease associated with the presence of cigarette smoking.

    abstract:OBJECTIVE:Cigarette smoking increases the synthesis of angiotensin-1 converting enzyme (ACE) and induces oxidative modifications of the apolipoprotein E (apo E).Thus we explored the gene-environment interactions between APOE gene epsilon and ACE gene insertion/deletion polymorphisms and cigarette smoking in coronary ar...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.63.6.2033392

    authors: Zak I,Niemiec P,Balcerzyk A,Krauze J

    更新日期:2008-12-01 00:00:00

  • Home-based cardiac rehabilitation decreases red cell distribution width in chronic heart failure.

    abstract:OBJECTIVE:Red cell distribution width (RDW) is a measure of variation in the volume of circulating erythrocytes and has recently emerged as a powerful prognostic marker in heart failure. We studied the effect of 5-month, home-based cardiac rehabilitation on RDW. METHODS AND RESULTS:Sixty-two patients (age: median 67 y...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.68.6.8000009

    authors: Mohri M,Motohama R,Sato N

    更新日期:2013-12-01 00:00:00

  • Heart rate variability and the outcome of head-up tilt in syncopal children.

    abstract:OBJECTIVE:This study evaluated autonomic nervous system function in 5 young (6-10 years old) and 5 older (10-15 years) children with recurrent episodes of neurally mediated syncope and a positive tilt-test result, 10 with syncope but a negative test result and 30 age-matched healthy volunteers. METHODS:Time- (SDNN, SD...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.55.3.2005734

    authors: Massin MM,Henrard V,Gerard P

    更新日期:2000-06-01 00:00:00

  • Subclinical arterial wall damage in patients at low to moderate cardiovascular risk.

    abstract:AIM:The aim of this paper is to study the degree of subclinical arterial wall damage in subjects at low and moderate risk of cardiovascular death by the SCORE scale using instrumental research methods. METHODS:We enrolled 600 patients (mean age 49.0 +/- 7.1 years, 74% women) with a calculated SCORE 5%, who passed a ca...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.70.3.3080631

    authors: Boytcov SA,Urazalina SJ,Kukharchuk VV,Balakhonova TV,Sergienko IV

    更新日期:2015-06-01 00:00:00

  • Aldosterone synthase -344C/T and angiotensin-converting enzyme I/D polymorphisms in Turkish hypertensive patients with normal coronary arteries.

    abstract:BACKGROUND:The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure regulation, left ventricular and vascular structure. Some hypertensive patients develop left ventricular dilatation and heart failure symptoms while others are relatively less affected. The purpose of our study was to d...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.61.1.2005137

    authors: Olcay A,Nisanci Y,Ekmekci CG,Umman B,Bugra Z,Sezer M,Acar RD,Ozbek U

    更新日期:2006-02-01 00:00:00

  • Congenital absence of the left atrial appendage: a rare anatomical variation with clinical significance.

    abstract::Congenital absence of the left atrial appendage (LAA) is extremely rare.We describe a case of congenial absence of the LAA in a patient scheduled for atrial fibrillation (AF) ablation. Absence of the LAA was found pre-procedurally by transoesophageal echocardiography (TEE) and cardiac computer tomography (CT). During ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.68.3.2983429

    authors: Zhang ZJ,Dong JZ,Ma CS

    更新日期:2013-06-01 00:00:00

  • Hemodynamics of the splanchnic and systemic circulation after hypotonic water load-comparison between normal subjects and patients with congestive heart failure.

    abstract::The authors investigated the changes in cardiovascular and splanchnic hemodynamic, diuresis and urinary and hepatic veins osmolarity induced by hypotonic water load in five normal subjects and in five patients with congestive heart failure (CHF). Pulmonary wedge pressure increased significantly only in CHF patients wh...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Ferrara N,Bonaduce D,Canonico V,Abete P,Rengo F,Condorelli M

    更新日期:1983-01-01 00:00:00

  • Clinical and coronary angiographic characteristics of patients with coronary slow flow.

    abstract:BACKGROUND:The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease, and is an important clinical entity because it may be the cause of angina at rest or during exercise, acute myocardial infarction, and h...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.63.5.2033224

    authors: Yilmaz H,Demir I,Uyar Z

    更新日期:2008-10-01 00:00:00

  • Prinzmetal's variant angina is effectively treated with enhanced external counterpulsation.

    abstract::A 57-year-old woman suffering from severe Prinzmetal's angina was treated with a 7-week course of enhanced external counterpulsation (EECP). After completing EECP the angina intensity was reduced from CCS class IV to class I, quality of life was increased and medication was significantly reduced. The number of hospita...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.65.2.2047066

    authors: Tarpgaard Jørgensen M,Gerdes C,May O

    更新日期:2010-04-01 00:00:00

  • The loss of entropy circadian rhythm in sinusal R-R intervals of type 1 diabetic pregnant women suggests an indeterministic chaos in cardiac pacing (minimum delirium cordis syndrome). A newly identifiable type of silent cardiac dysautonomia?

    abstract:OBJECTIVE:The scope of this study is to detect whether or not the entropy (E) circadian rhythm (CR) is maintained preserved in sinusal R-R intervals (SRRI), its loss being the expression of a transition to an indeterministic chaos in heart rate variability (HRV). METHODS:The E of SRRI was estimated in 14 type I diabet...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/ac.62.3.2020814

    authors: Cugini P,Curione M,Castro C,Napoli A,Francia P,Colatrella A,Di Bona S,Cammarota C,Cardarelli G,Amato S,Fallucca F

    更新日期:2007-06-01 00:00:00

  • Analysis of physical exercise in cardiac patients following cardiovascular rehabilitation.

    abstract::Background: Cardiovascular rehabilitation and retraining seek to increase cardiorespiratory fitness and to manage certain risk factors such as smoking, hypercholesterolaemia and sedentary lifestyle. Such lifestyle changes can be influenced by a combination of health determinants. Aim: The purpose of this study is to a...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2019.1639269

    authors: Racodon M,Pezé T,Masson P

    更新日期:2019-07-17 00:00:00

  • Extra- and intracellular recordings from the avjunction: discerning the mechanisms for irregular ventricular responses during supraventricular arrhythmias.

    abstract:INTRODUCTION:There has been a long-standing controversy regarding the mechanism(s) to explain the irregular ventricular response during atrial tachycardia (AT) or atrial fibrillation (AF) and where the site of block, if any, resides in the atrioventricular (AV) junction. METHODS:We studied 12 Langendorff preparations ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.67.2.2154213

    authors: Liu Y,Scherlag BJ,Yagi T,Patterson E,Jackman WM,Lazzara R,Po SS

    更新日期:2012-04-01 00:00:00

  • Echocardiographic diagnosis of systemic AA amyloidosis presenting with acute liver failure.

    abstract::We report the case of a 73-year-old man admitted to our hospital for acute hepatic failure. Antemortem diagnosis of systemic AA amyloidosis was made because of typical electrocardiographic and echocardiographic findings, in the absence of the classic clinical picture of kidney involvement. ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.65.4.2053906

    authors: Morelli S,Bonfiglio D,Galasso L

    更新日期:2010-08-01 00:00:00

  • Echocardiography and the clinical diagnosis of left ventricular dysfunction.

    abstract:INTRODUCTION:The added value of routine echocardiography, in respect to clinical examination and ECG, has received little attention. We sought to evaluate the contribution of two-dimensional echocardiography, in respect to clinical examination and ECG, in detecting left ventricular (LV) dilatation and systolic dysfunct...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.63.4.2033051

    authors: Rovai D,Morales MA,Di Bella G,Prediletto R,De Nes M,Pingitore A,Rossi G

    更新日期:2008-08-01 00:00:00

  • Implantable Holter may reveal cause of unexplained syncope.

    abstract::A definitive diagnosis in patients with syncope is often problematic if the cause is not evident after initial clinical assessment. The cause of syncope may be not established due to the infrequent, episodic occurrence. A symptom-rhythm correlation is frequently an unattainable gold standard in many patients. The impl...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Dionísio P,Vestraets A,Vandenbulcke F,Depuydt P,Stroobandt R

    更新日期:1998-01-01 00:00:00

  • Prognostic nutritional index predicts one-year outcome in heart failure with preserved ejection fraction.

    abstract::Background: This study aimed to examine the value of prognostic nutritional index (PNI) as a predictor of outcomes in patients with heart failure and preserved ejection fraction (HFpEF).Methods: We prospectively followed consecutive adult patients admitted to the cardiology outpatient units with HFPEF. Echocardiograph...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2019.1661139

    authors: Zencirkiran Agus H,Kahraman S

    更新日期:2020-09-01 00:00:00

  • Using aortic distensibility index to detect coronary stenosis.

    abstract:OBJECTIVE:The aortic distensibility index, as a measure of vascular function, can serve as a marker of coronary artery disease severity. This study explores the feasibility of using the non-invasively measured index as an indicator of severity of coronary stenosis. METHODS:One hundred patients with normal left ventric...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.70.4.3096895

    authors: Shehata M,Elsayegh A,Gomaa Y,Gamal M

    更新日期:2015-08-01 00:00:00

  • Influence of percutaneous transcatheter closure of an atrial septal defect on the atrioventricular conduction.

    abstract:OBJECTIVE:This study aimed at determining the effect of percutaneous ASD closure on the AV conduction. Percutaneous closure of ostium secundum atrial septal defects (ASDs) has been widely accepted and has become the standard treatment of this malformation. However, some complications have been reported. Because of the ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.66.3.2114130

    authors: Cottens D,Van De Bruaene A,Troost E,Willems R,Moons P,Budts W

    更新日期:2011-06-01 00:00:00

  • The relationship between serum lectin-like oxidized LDL receptor-1 levels and systolic heart failure.

    abstract:OBJECTIVES:Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) appears to be involved in atherosclerotic plaque vulnerability and rupture. In this study, we aimed to evaluate the utility of serum LOX-1 levels in the diagnosis and assessment of left ventricular systolic HF and LOX-1’s relationship with serum...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.71.2.3141848

    authors: Besli F,Gullulu S,Sag S,Kecebas M,Acikgoz E,Sarandol E,Aydinlar A

    更新日期:2016-04-01 00:00:00

  • Risk assessment for percutaneous coronary intervention of the unprotected left main coronary artery in a real-world population.

    abstract:BACKGROUND:Available clinical and angiographic scoring systems fail to predict clinical outcomes in real-world patients undergoing revascularization of the unprotected left main coronary artery (ULMCA). METHODS:We prospectively assessed major adverse cardiac and cerebrovascular events (MACCE) in a real-world populatio...

    journal_title:Acta cardiologica

    pub_type: 杂志文章,多中心研究

    doi:10.1080/ac.67.5.2174124

    authors: Kayaert P,Desmet W,Sinnaeve P,Adriaenssens T,Coosemans M,Ferdinande B,Dubois C

    更新日期:2012-10-01 00:00:00

  • Challenges of cardiology and cardiovascular surgery in 1958.

    abstract::The Cardiology Foundation supported by the perspicacious Princess Lilian was created in 1958. As an introduction to this symposium, the challenges that the cardiologist and surgeon encountered in 1958, are recalled as well as the essential problems requiring solutions in that era of evolving cardiac surgery. ...

    journal_title:Acta cardiologica

    pub_type: 历史文章,杂志文章

    doi:

    authors: Primo G

    更新日期:2004-01-01 00:00:00

  • Prognostic value of carbohydrate antigen 125 combined with N-terminal pro B-type natriuretic peptide in patients with acute heart failure.

    abstract::Background: The objective was to explore the value of serum carbohydrate antigen 125 (CA125) combined with N-terminal pro B-type natriuretic peptide (NT-proBNP) in predicting the clinical prognosis of patients with acute heart failure (AHF).Methods: We prospectively observed 213 patients with AHF. CA125 (U/ml) and NT-...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2020.1769347

    authors: Chen X,Wu M,Xu K,Huang M,Zhuo X

    更新日期:2020-06-10 00:00:00

  • Ventricular tachycardia induced by a pacemaker lead.

    abstract::The authors present a case of symptomatic non-sustained ventricular tachycardia induced by mechanical irritation of the outflow tract of the right ventricle by a loop in a permanent ventricular pacing lead. Reposition of the lead eliminated the rhythm disturbance. ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.57.1.2005375

    authors: Bõhm A,Pintér A,Préda I

    更新日期:2002-02-01 00:00:00

  • Haem oxygenase-1 expression and coronary heart disease--association between levels of haem oxygenase-1 expression and angiographic morphology as well as the quantity of coronary lesions.

    abstract:OBJECTIVE:The aim of this paper was to investigate the association between levels of HO-1 expression and angiographic morphology as well as the quantity of coronary lesions in patients with coronary heart disease (CHD). METHODS:110 patients with CHD were diagnosed by coronary angiography which contained coronary lesio...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.61.3.2014831

    authors: Li YG,Wang DM,Chen SM,Tan XR,Fang XY,Wu JW,Zhang GH,Mai RQ

    更新日期:2006-06-01 00:00:00

  • The effect of piroxicam on the prevention of postoperative retrosternal and pericardial adhesions.

    abstract:BACKGROUND:The presence of adhesions after heart operations increases the risk of life-threatening damage to the heart and extracardiac grafts. Infections, tissue injury and inflammations are suspected aetiologic agents. The main purpose of our study is to evaluate the effect of an antiinflammatory agent piroxicam on t...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.62.6.2024014

    authors: Iskesen I,Aksoy O,Cerrahoglu M,Sirin H

    更新日期:2007-12-01 00:00:00