Abstract:
BACKGROUND:The presence of adhesions after heart operations increases the risk of life-threatening damage to the heart and extracardiac grafts. Infections, tissue injury and inflammations are suspected aetiologic agents. The main purpose of our study is to evaluate the effect of an antiinflammatory agent piroxicam on the formation of retrosternal and pericardial adhesions in a rabbit model. MATERIAL AND METHODS:23 of forty-two New Zealand white rabbits were labelled as group P (piroxicam group) and the others as group C (n = 19, control group). All animals were subjected to median sternotomy and abrasion was applied to the epicardium and pericardium. Piroxicam was given only to group P animals 10 mg/kg/day intramuscularly on the day of operation and twice daily for 2 days postoperatively. All animals were sacrificed on the 10th postoperative day. After cardiectomy, the pericardium was totally excised; retrosternal and pericardial adhesions were evaluated and scored. t-PA (tissue plasminogen activator), PAl-I (plasminogen activator inhibitor-I) levels and pericardial tissue myeloperoxidase activities were measured. RESULTS:More severe retrosternal and pericardial adhesions were observed in the control group (P < 0.05). Mean levels of t-PA were higher in the study group than in the control group (P < 0.05). Mean levels of PAI-I were lower in the study group (P < 0.05). Hence pericardial fibrinolytic capacity was significantly higher in the piroxicam group than in the control group. Myeloperoxidase activities in the pericardium were significantly lower in the study group than in the control group (P < 0.05). CONCLUSION:The use of piroxicam in the perioperative period prevents inflammation, preserves the fibrinolytic capacity of the pericardium and decreases the postoperative pericardial and retrosternal adhesions.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Iskesen I,Aksoy O,Cerrahoglu M,Sirin Hdoi
10.2143/AC.62.6.2024014subject
Has Abstractpub_date
2007-12-01 00:00:00pages
559-64issue
6eissn
0001-5385issn
1784-973Xjournal_volume
62pub_type
杂志文章abstract::Pulmonary dissemination of a cardiac cyst is a rare condition. In the present study, we report a case of a 20-year-old patient with cardiac hydatosis located in the interventricular septum, which was previously diagnosed and treated as pulmonary hydatid disease. Diagnosis was made by spiral computed tomography and tre...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.5.2005309
更新日期:2003-10-01 00:00:00
abstract::The increasing number of amateur sportsmen enhances the need for a correct evaluation of subjects suspected of overt and mild cardiac disease. Out of 4000 athletes, 72 subjects were clinically preselected by the sport doctor during an annual routine examination. They were studied with mono and 2D echo, pulsed color (P...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:The effects of cigarette smoking on the circadian rhythm of heart rate variability (HRV) are not known. METHODS:We studied the effects of cigarette smoking on the circadian rhythm of HRV in 24 smoking and 21 non-smoking healthy subjects. Twenty-four hour ambulatory electrocardiograms were recorded and time ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.55.5.2005757
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:The Gubbio Study is an Italian population study measuring risk factors for and incidence of major cardiovascular diseases. This analysis investigates the association of serum uric acid with the incidence of coronary and cardiovascular events. METHODS:A population sample of 2469 men and women aged 35-74 years...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.56.4.2005651
更新日期:2001-08-01 00:00:00
abstract::Background: Defibrillation threshold testing (DT) following implantable cardioverter defibrillator (ICD) implantation has not shown to improve mortality. However, the impact of DT on burden of heart failure (HF) hospitalisations has not been well defined.Methods: We studied retrospectively consecutive patients who und...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1630586
更新日期:2020-06-01 00:00:00
abstract::The optimal management of high-risk patients requiring urgent or emergency noncardiac surgery when the options for further testing and evaluation are limited, is unclear. The focus of most of the literature, including the American College of Cardiology/American Heart Association guidelines, has been on patients underg...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.5.2004980
更新日期:2005-10-01 00:00:00
abstract::Background: The presence of intracoronary thrombus is associated with increased ischaemic complications in patients with NSTEMI. High thrombus burden is an independent predictor of major adverse cardiovascular events, stent thrombosis and no reflow in patients with STEMI. CHA2DS2-VASc score predicts thrombus burden in...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1707934
更新日期:2020-01-03 00:00:00
abstract::In eighteen consecutive patients (14 male, 4 females, in the age 37-52 years, mean = 43 years) with dilated cardiomyopathy in NYHA functional classification groups III-IV, the efficacy of ambulatory long-term (mean = 6 years) vasodilator therapy by means mechanocardiography (systolic and diastolic time intervals) and ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::An anomalous origin of the right coronary artery from the left sinus of Valsalva with an interarterial course is a rather rare congenital anomaly. Treatment strategies are determined by the risk of sudden cardiac death and the presence of cardiac ischaemia. We present two cases of middle-aged patients who were diagnos...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.2.3017300
更新日期:2014-04-01 00:00:00
abstract::Diffuse intra-alveolar haemorrhage is a rare complication of thrombolytic therapy (TT). We report a patient who developed haemoptysis due to pulmonary haemorrhage. This diagnosis should be considered in any patients with respiratory distress, diffuse pulmonary infiltrates, and haemoptysis and otherwise unexplained dec...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.3.2005194
更新日期:2004-06-01 00:00:00
abstract:AIM:To determine whether statin therapy initiated early in acute myocardial infarction together with thrombolytic therapy in patients with acute myocardial infarction results in clinical benefit through early plaque stabilization. METHODS AND RESULTS:The study population consisted of 77 patients who underwent coronary...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2143/AC.57.4.2005430
更新日期:2002-08-01 00:00:00
abstract::Background: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking. Therefore, this study aimed to determine which QIs, rooted in the electronic health record (EHR), are useful to monitor quality of care for pa...
journal_title:Acta cardiologica
pub_type: 共识发展会议,杂志文章,评审
doi:10.1080/00015385.2018.1492659
更新日期:2019-08-01 00:00:00
abstract::Enalapril is a new angiotensin converting enzyme inhibitor which, when absorbed by the digestive tract, is converted to enalaprilat. This metabolite is, in fact, the active form of enalapril. Its duration of action is sufficiently long so that enalapril can be administered in a single daily dose. Enalapril has been pr...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:The main function of hepatic lipase (HL) with respect to high-density lipoprotein (HDL) is hydrolysis of phospholipids and triglycerides. The -514C-->T polymorphism in the promoter region of the hepatic lipase gene affects HL activity. We aimed to investigate the association between the frequency of the -514C...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.2.2029528
更新日期:2008-04-01 00:00:00
abstract::Atrial bigeminy is a supraventricular arrhythmia rarely associated with severe symptoms. We report the case of a 22-year-old woman with no prior cardiac disease presenting with exercise intolerance since several months. No apparent heart disease other than a spontaneous conducted atrial bigeminy with a short coupling ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126602
更新日期:2011-08-01 00:00:00
abstract::We investigated the clinical significance of recovery systolic blood pressure (SBP) ratio, obtained dividing the recovery SBP at 1st (R1/A) or 3rd min (R3/A) by the peak exercise SBP (before stopping), during upright bicycle exercise in 530 subjects (ranging from 17 to 73 years). Our results may be summarized as follo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Transradial approach to coronary angiography is a progressive and increasingly more often used technique. Apart from its advantages, radial artery occlusion (RAO) represents the most serious drawback. Re-canalization of an iatrogenic RAO, although asymptomatic in the majority of cases, remains a discussed and challeng...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.3.2160731
更新日期:2012-06-01 00:00:00
abstract::In chronic aorto-iliac occlusive disease, pre-existing renal artery stenosis may give rise to sufficient development of collateral blood flow and prevent ischaemic symptoms for a long time and therefore may cause delay in diagnosis. An early diagnosis of aorto-iliac disease is necessary in order to avoid fatal outcome...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.3.2038035
更新日期:2009-06-01 00:00:00
abstract::Primary ventricular fibrillation especially occurs during the first hours after acute myocardial infarction and is often not preceded by premonitory ventricular premature beats. In hospital primary ventricular fibrillation can be prevented by an intravenous lidocaine regimen in a rather high dosage. By contrast the ef...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to analyse age-related changes in human myocardial nerve plexuses and collagen networks of the auricle of the right atrium in subjects in whom no cardiac diseases or pathology had been diagnosed. METHODS AND RESULTS:Morphometric analysis of acetylcholinesterase (AChE)-stained ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.5.2017765
更新日期:2006-10-01 00:00:00
abstract::Background: AF, anticoagulation, NOACs, changing patterns of prescription. Methods: We describe baseline data and treatment patterns of patients recruited in Belgium in the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF). Recruitment began when novel oral anticoagulants (NOACs) were introd...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00015385.2018.1494089
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate pain and pulmonary function after partial upper versus complete sternotomy for aortic valve surgery. METHODS AND RESULTS:In a prospective study of 31 adult patients, 15 individuals underwent aortic valve replacement via partial upper sternotomy, and 16 patients were oper...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.1.2005254
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:Left ventricular thrombus (LVT) is one of the important complications of acute anterior wall myocardial infarction (MI). Mean platelet volume (MPV) is one of the platelet indices reflecting platelet reactivity. In this present study we investigated the effect of MPV on LVT formation after primary percutaneous...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.69.6.1000002
更新日期:2014-12-01 00:00:00
abstract::The aim of our study is to evaluate the prognostic value of heart rate turbulence and heart rate variability in children with dilated cardiomyopathy (DCM). Twenty-five children with DCM and 24 age- and sex-matched healthy children who were admitted between January 2002 and September 2004, enrolled in this prospective ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.62.1.2019368
更新日期:2007-02-01 00:00:00
abstract::Purulent pericarditis is rarely the primary site of bacterial infection. It is usually a complication of an infection originating elsewhere in the body, arising by contiguous spread or haematogenous dissemination.This paper, however, describes a previously healthy young man, who developed a purulent streptococcal peri...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.5.2005459
更新日期:2002-10-01 00:00:00
abstract::This is a report on a prospective case-control study, in which a group of patients with an electrocardiographic diagnosis of QTc-prolongation (cases) was compared with a group of patients with a normal QTc (controls) for the presence of potential causative factors. Twelve cases and twelve carefully-matched controls we...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:This study evaluated autonomic nervous system function in 5 young (6-10 years old) and 5 older (10-15 years) children with recurrent episodes of neurally mediated syncope and a positive tilt-test result, 10 with syncope but a negative test result and 30 age-matched healthy volunteers. METHODS:Time- (SDNN, SD...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.55.3.2005734
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVES:The role of adenosine as a cardioprotective agent is well known and recent experimental studies suggest that impairment of adenosine-related signal transduction contributes to the pathophysiology of chronic heart failure. The recent observation of an association between ADA, genetic polymorphism and coronary...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.1.3011343
更新日期:2014-02-01 00:00:00
abstract:UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036136
更新日期:2009-04-01 00:00:00