Is K-O Tab 1-2-3((R)) long lasting on non-polyester mosquito nets?

Abstract:

:Many societies use locally sourced mosquito nets made from a variety of materials. For protecting against malaria these require regular re-treatment with insecticide. K-O Tab 1-2-3 is a 'dip-it-yourself' long-lasting formulation with time-limited interim recommendation from WHO for treatment of washed white and coloured polyester nets for up to 15 washes. To determine wash-resistance on different fabrics, nets made of polyester, polyethylene, cotton or nylon were treated with K-O Tab 1-2-3 and washed up to 20 times using standard WHO washing procedures. Efficacy was assessed using cone and cylinder bioassays and tunnel tests, and deltamethrin content using high-pressure liquid chromatography. Polyethylene and cotton nets treated with K-O Tab 1-2-3 and washed 20 times achieved the WHO threshold of >80% mortality in tunnel tests. Polyethylene matched the performance of polyester in all bioassays in contrast to cotton and nylon which produced low mortality and knock-down in cone and cylinder bioassays. After 20 washes 16.5% of the loading dose of deltamethrin remained on the polyester nets compared with 28.7% on polyethylene, 38.9% on cotton and 2.2% on nylon. Cotton nets retained a high concentration of insecticide but the relatively poor performance in terms of knock-down and mortality suggest most insecticide is bound within the cotton fibres rather than on the surface. K-O Tab 1-2-3 renders insecticide wash fast on polyethylene nets, less so on cotton and nylon. Nets made from polyethylene can be treated in the home to render the insecticide long lasting.

journal_name

Acta Trop

journal_title

Acta tropica

authors

Oxborough RM,Weir V,Irish S,Kaur H,N'Guessan R,Boko P,Odjo A,Metonnou C,Yates A,Akogbeto M,Rowland MW

doi

10.1016/j.actatropica.2009.06.005

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

49-53

issue

1

eissn

0001-706X

issn

1873-6254

pii

S0001-706X(09)00156-9

journal_volume

112

pub_type

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