Abstract：
:The clinicoepidemiologic profile of 143 cases (93 males and 50 females) with cutaneous leishmaniasis from 18 villages of Hajjah governorate, Yemen was studied. Dry-type lesions were seen in 98.6% and wet-type lesions in 1.4% of patients. Lesions were localized in all cases with different morphological patterns. Microscopic examination of Giemsa-stained slit smears revealed amastigotes in 74.1% of patients with dry-type lesions and 0% in patients with wet-type lesions. The burden of the parasites in the lesions was high indicating active transmission of the disease. Most cases were from villages with moderate altitude range (8001-1600m). All age groups were affected, but most cases were seen in ages from 5 to 15 years. Leishmania species identification was done for all cases by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The biopsic material was scraped from both Giemsa-stained and methanol-fixed smears. The molecular characterization of Leishmania species revealed Leishmania tropica as the causative agent of cutaneous leishmaniasis in Hajjah, Yemen. The risk factors associated with the transmission of the disease and recommendations for improving case detection were discussed.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Mogalli NM,El Hossary SS,Khatri ML,Mukred AM,Kassem HA,El Sawaf BM,Ramadan NFdoi
10.1016/j.actatropica.2016.08.012subject
Has Abstractpub_date
2016-11-01 00:00:00pages
130-4eissn
0001-706Xissn
1873-6254pii
S0001-706X(16)30194-2journal_volume
163pub_type
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