Abstract:
:Diagnosis of neurocysticercosis (NCC) is complicated because of the variability in clinical presentations and course of the disease where viability of parasite is a major determinant. The present study describes evaluation of ELISAs using Taenia solium metacestode somatic and excretory-secretory (ES) antigens for detection of anti-T. solium metacestode IgG antibodies in serum and cerebrospinal fluid (CSF). And results of the ELISAs in cases with a definitive diagnosis of NCC are correlated with the biological stages of the parasite such as live vesicular or degenerated stage. The sensitivity of the IgG-ELISA using ES antigen is observed to be much higher in serum (88.2%) than in CSF (64.28%) although it is only marginally higher in serum (76.4%) than in CSF (75%) when somatic antigen is used in the ELISA. Whereas, the specificities of the ELISA using either somatic or ES antigen for detection of IgG antibodies in serum (97.97%; 96.96%) and CSF (96.42%; 97.61%) are comparable. A strong association is observed between live stage of the parasite and detection of antibodies in sera and CSF from more number of NCC patients by ELISA using ES antigens. Similarly, detection of antibodies by ELISA using somatic antigens could be associated with the dead or degenerated stage of the parasite in brain. The IgG-ELISA strategy developed in the present study opens up an avenue for diagnosis of NCC in hospitals or in population prevalence studies. The use of crude extracts of ES proteins might improve the serodiagnosis of the cases of NCC carrying live vesicular stage of the parasite larvae.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Sahu PS,Parija SC,Narayan SK,Kumar Ddoi
10.1016/j.actatropica.2009.01.002subject
Has Abstractpub_date
2009-04-01 00:00:00pages
38-45issue
1eissn
0001-706Xissn
1873-6254pii
S0001-706X(09)00003-5journal_volume
110pub_type
杂志文章相关文献
ACTA TROPICA文献大全abstract::Heartwater caused by Ehrlichia ruminantiumis a disease of domestic and wild ruminants and one of the most economically important tick-borne diseases in Africa. The present study aimed to investigate the occurrence and genetic diversity of E. ruminantium in blood samples from 210 cattle sampled in five districts of Map...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.01.007
更新日期:2019-03-01 00:00:00
abstract::The main objective of the present study was to evaluate the potential of eriosematin E (ECM) isolated from the roots of Eriosema chinense against enteropathogenic Escherichia coli (EPEC) induced diarrhoea. ECM isolated from the bioactive chloroform fraction of E. chinense was subjected to antidiarrhoeal evaluation on ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.02.025
更新日期:2019-05-01 00:00:00
abstract::Six Cercopithecus aethiops monkeys, 4 Theropithecus gelada baboons and 2 Papio anubis baboons were infected using Leishmania aethiopica isolates originating either from localized (LCL) or diffuse (DCL) cutaneous leishmaniasis patients. The history of lesions in 4 C. aethiops monkeys infected by LCL strains mimicked th...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(95)00085-s
更新日期:1995-06-01 00:00:00
abstract::Leishmaniasis, a zoonotic disease caused by parasites of the genus Leishmania, has expanded beyond its natural range and is becoming increasingly urban. Using PCR and PCR-RFLP, we detected Leishmania (Viannia) braziliensis in two bats (Chiroptera) in Mato Grosso do Sul, Brazil, an endemic area. This is the first recor...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2013.07.004
更新日期:2013-10-01 00:00:00
abstract::In the Caribbean region of Colombia, Lutzomyia evansi is recognized as the vector for Leishmania infantum and Leishmania braziliensis. Identifying breeding sites and surveying abundance of immature phlebotomine sand flies in urban foci of leishmaniasis are useful tool to design new vector control strategies. The objec...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2020.105523
更新日期:2020-05-12 00:00:00
abstract::Global demand for food is surging upward due to the expansion of human population. Hence food production and supply need to double with little or no waste to meet this demand. Food loss at any point in the farm to fork chain inhibits the stability of food security at household and national level. A retrospective (AR) ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2017.12.007
更新日期:2018-02-01 00:00:00
abstract::The efficacy of a 5-day treatment with intramuscular artemether (3.2-mg/kg loading dose followed by 1.6 mg/kg daily) was compared to that of the standard 7-day treatment with quinine (20-mg/kg loading dose followed by 10 mg/kg every 8 h) in a randomised clinical trial including 103 children aged 12-60 months with cere...
journal_title:Acta tropica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0001-706x(99)00031-5
更新日期:1999-10-15 00:00:00
abstract::Schistosomiasis has plagued the Egyptian population since the antiquity. The disease is still a public health problem in Egypt, despite the tendency of being overlooked. In the first part of this review, the past and current trends of schistosomiasis in Egypt are reviewed, including history, epidemiology, morbidity, t...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2015.04.016
更新日期:2015-08-01 00:00:00
abstract::Trypanosomes are parasitic flagellate protozoans that are important disease causing agents in humans and animals including economically significant livestock. Many blood-sucking insects are known to be vectors of trypanosomes but there is no data for the haematophagous black fly species in Asia. In this study, a molec...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.105196
更新日期:2019-12-01 00:00:00
abstract::Visceral leishmaniasis (VL) is a serious and widespread parasitic disease caused by Leishmania donovani complex. The threat of this fatal disease continues due to the lack of ideal drugs or vaccines. In this study, we selected Amastin, CaNA2, Kmp-11 and PDI proteins of Leishmania donovani for study, which are VL vacci...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.12.035
更新日期:2019-03-01 00:00:00
abstract::Transmission risk for vector borne disease is greatest during periods of heightened vector activity. Triatomine bugs (Hemiptera: Reduviidae), which transmit Trypanosoma cruzi, the causative agent of Chagas disease, are generally considered nocturnal, but their patterns of activity in controlled settings have rarely be...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.06.012
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Existing data on human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense among children are limited. Here, we described the demographic, clinical, diagnostic, treatment and outcome characteristics of HAT in pre-school children from Kajo-Keji County, South Sudan in comparison with older patien...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2006.12.002
更新日期:2007-01-01 00:00:00
abstract::In this study, Aphanius chantrei's behaviour of feeding on mosquito larvae has been determined under experimental conditions. In groups that have different sizes (first group 27 mm; second group 40 mm; third group 47 mm), larvae consumption has increased with length and weight. During daytime, average larvae consumpti...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2007.04.016
更新日期:2007-06-01 00:00:00
abstract::Opisthorchis viverrini infection, opisthorchiasis, is a food-borne trematodiasis that is the main cause of cholangiocarcinoma, a bile duct cancer, in the Lower Mekong sub-region of Lao PDR, Cambodia, Vietnam, and Thailand. Despite extensive research on opisthorchiasis, the eradication of this disease has yet to be ach...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2019.05.011
更新日期:2019-08-01 00:00:00
abstract::Assessing the biting behaviour of malaria vectors plays an integral role in understanding the dynamics of malaria transmission in a region. Biting times and preference for biting indoors or outdoors varies among mosquito species and across regions. These behaviours may also change over time in response to vector contr...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.105059
更新日期:2019-09-01 00:00:00
abstract::We aimed to systematically review evidence pertaining to the safety and efficacy of nitazoxanide in treating infectious diarrhea. On September 21, 2017, we identified relevant studies using 12 databases. The estimates of the included studies were pooled as a risk ratio (RR). We conducted a network and pairwise random-...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2020.105603
更新日期:2020-10-01 00:00:00
abstract::Pangonius theodori a new horse fly species (Diptera: Tabanidae: Pangoniinae) from northern Israel and southern Lebanon is described. The zoogeography, habitat preference and taxonomic position within the genus of the new species is discussed in detail. ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2012.11.009
更新日期:2013-03-01 00:00:00
abstract::Artificial feeding of the insects with whole blood containing trypomastigotes resulted in triatome infection; the parasites were present in the host feces after 15--30 days and, when inoculated into mice, elicited parasitemia in 100% of the cases and deaths in 20--70%. This mortality indicates a reduction of the origi...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract::India and other Southeast Asian countries are severely affected by Japanese encephalitis (JE), one of the deadliest vector-borne disease threat to human health. Several epidemiological observations suggest climate variables play a role in providing a favorable environment for mosquito development and virus transmissio...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2020.105701
更新日期:2020-12-01 00:00:00
abstract::A simple, rapid and inexpensive method for the extraction of DNA from filarial vector, Culex quinquefasciatus, useful in Ssp I PCR assay for xenomonitoring of infection with Wuchereria bancrofti is presented. The DNA extracted by this method was found suitable for PCR detection of W. bancrofti infection in pools of 10...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(02)00267-x
更新日期:2003-04-01 00:00:00
abstract::Rabies is one of the most dreadful diseases and a major viral zoonosis which has been shown to cause an almost 100% fatality rate in infected victims. It is characterized by acute progressive encephalitis in mammals. This study determined the genotypic characteristics of rabies virus in dogs slaughtered for human cons...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2020.105461
更新日期:2020-07-01 00:00:00
abstract::We report results of Trypanosoma cruzi infection and parasite genotypes in the wild Octodon degus and synantropic reservoir Rattus rattus from an endemic area with sylvatic Triatoma infestans as the only detected vector. The infection status was determined by hemi-nested PCR directed to minicircles DNA and genotyping ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2009.02.010
更新日期:2009-07-01 00:00:00
abstract::There are many fundamental aspects of the immunobiology of Plasmodium falciparum infections that are not fully understood, therefore limiting our comprehension of how people become immune to malaria and why some ethnic groups living in malaria endemic areas are less susceptible than others. The complexity of parasite-...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2015.03.023
更新日期:2015-06-01 00:00:00
abstract::Sm14 and paramyosin are two major Schistosoma mansoni vaccine candidate antigens. Recently, we have identified Sm14 and paramyosin epitopes that are recognized by T cells of resistant individuals living in endemic areas for schistosomiasis. Herein, mice were immunized with these peptides separately or in association i...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2008.03.003
更新日期:2008-06-01 00:00:00
abstract::With the paradigm shift from the reduction of morbidity and mortality to the interruption of transmission, the focus of malaria control broadens from symptomatic infections in children ≤5 years of age to include asymptomatic infections in older children and adults. In addition, as control efforts intensify and the num...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2011.11.009
更新日期:2012-03-01 00:00:00
abstract::A PCR-RFLP based method was developed to diagnose and identify the Leishmania species causing American cutaneous leishmaniasis (ACL) in a panel of clinical samples obtained from an endemic region of Brazil. The comparison of the results obtained by PCR-RFLP and PCR-hybridization in the identification of Leishmania (Vi...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2003.10.008
更新日期:2004-03-01 00:00:00
abstract::The 4-year (2006-2010) alliance to optimize schistosomiasis control and transmission surveillance in sub-Saharan Africa (CONTRAST), funded by the European Commission, stands out as a 'game-changer' by successfully harnessing and combining new as well as previously available capabilities for schistosomiasis control in ...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2013.08.016
更新日期:2013-11-01 00:00:00
abstract::The levels of immunoglobulin classes (IgG, IgM and IgA) along with B lymphocyte population size were estimated in 24 kala-azar (KA) patients and results were compared with those obtained from 30 controls. A marked increase in the level of IgG and to a lesser extent in that of IgM was noted in the sera of KA patients. ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1986-09-01 00:00:00
abstract::Time to death from starvation and compulsive killing without eating of the prey by larvae of Toxorhynchites splendens were studied in the laboratory. The first and second instars survived without food for 3 days while third and fourth instars survived for 7.8 and 14 days, respectively. When the corresponding instars o...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(94)90054-x
更新日期:1994-11-01 00:00:00
abstract::Antimicrobial resistance results in selective colonization in animals. In the present study, 447 diarrheic foals (235 horse foals, 165 donkey foals and 47 mule foal) were selected from Lahore and Sahiwal districts of Punjab, Pakistan. Fresh fecal and blood samples from diarrheic foals were collected for isolation and ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2017.08.003
更新日期:2017-12-01 00:00:00