MicroRNA involvement in glioblastoma pathogenesis.

abstract：:Two genes encoding family 11 endo-beta-1,4-xylanases (XylA, XylB) from Fusarium graminearum were cloned and expressed in Escherichia coli. The amount of active endoxylanase in the cytoplasmic soluble fraction was considerably improved by varying different expression parameters, including host strain and temperature du...

journal_title：Biochemical and biophysical research communications

authors： Beliën T,Van Campenhout S,Van Acker M,Volckaert G

更新日期：2005-02-11 00:00:00

abstract：:Both the epidermal growth factor receptor (EGFR) and type 1 insulin-like growth factor receptor (IGF1R) require homo- and hetero-dimerisation with their own family members to acquire full function. We recently showed that IGF1R gene silencing led to EGFR hyper-phosphorylation in human breast cancer cells, and hypothes...

journal_title：Biochemical and biophysical research communications

authors： Riedemann J,Takiguchi M,Sohail M,Macaulay VM

更新日期：2007-04-13 00:00:00

abstract：:The molecular mechanism of the phosphorylation-dependent activation of tryptophan hydroxylase is studied with respect to the role of the 14-3-3 protein. Reexamination of the system reconstituted with the purified TRH and the 14-3-3 protein showed that the level of the TRH activity correlated with the extent of the Ca2...

journal_title：Biochemical and biophysical research communications

authors： Furukawa Y,Ikuta N,Omata S,Yamauchi T,Isobe T,Ichimura T

更新日期：1993-07-15 00:00:00

abstract：:The composition of intestinal glycosphingolipids during normal and hormone-perturbed development was investigated. The concentrations of glycosphingolipids of mouse small intestine were affected by the injection of thyroxine or cortisone during suckling and weaning periods. GDla was reduced by the hormonal treatment a...

journal_title：Biochemical and biophysical research communications

authors： Sato E,Fujie M,Uezato T,Fujita M,Nishimura K

更新日期：1984-03-30 00:00:00

abstract：:The bacterial superantigen staphylococcal enterotoxin A (SEA) is a potent inducer of CTL activity and cytokine production in vivo. Protein A (PA) of Staphylococcal aureus has been found to have diverse biological response modifying properties and to possess antitumor, antitoxic and antiparasitic effects. In this study...

journal_title：Biochemical and biophysical research communications

authors： Mondal TK,Bhatta D,Biswas S,Pal P

更新日期：2002-02-01 00:00:00

abstract：:Although major depressive disorder (MDD) has caused severe mental harm to overwhelming amounts of patients, the pathogenesis of MDD remains to be studied. Due to the in-depth discussion of the mechanism of new antidepressants like ketamine, the habenula (Hb) was reported to be significant in the onset of MDD and the a...

journal_title：Biochemical and biophysical research communications

authors： Tian Y,Wu Z,Wang Y,Chen C,He Y,Lan T,Li Y,Bai M,Yu H,Chen X,Chen Z,Cheng K,Xie P

更新日期：2021-01-01 00:00:00

abstract：:Extracellular superoxide dismutase (EC-SOD) is the major isozyme of SOD in arteries, but is also abundant in lungs. In particular, mouse lungs contain large amounts of EC-SOD compared to lungs in other mammals. This suggests that EC-SOD may have an amplified function in the mouse lung. This study describes the purific...

journal_title：Biochemical and biophysical research communications

authors： Fattman CL,Enghild JJ,Crapo JD,Schaefer LM,Valnickova Z,Oury TD

更新日期：2000-08-28 00:00:00

abstract：:Epigenetic gene silencing by aberrant DNA methylation leads to loss of key cellular pathways in tumorigenesis. DNA methylation-mediated silenced genes in pancreatic cancer were searched for using the methyl-CpG targeted transcriptional activation (MeTA) method, and LHX6 (LIM homeobox 6), a transcription factor involve...

journal_title：Biochemical and biophysical research communications

authors： Abudurexiti Y,Gu Z,Chakma K,Hata T,Motoi F,Unno M,Horii A,Fukushige S

更新日期：2020-06-04 00:00:00

abstract：:Glycated insulin was evaluated in plasma and biological tissues of diabetic animal models by immunocytochemistry (ICC) and a novel radioimmunoassay. Glycated insulin circulated at 0.10 +/- 0.04 ng/ml and 2.20 +/- 0.14 ng/ml in lean and diabetic obese (ob/ob) mice, corresponding to 12.5 and 9.8% total plasma insulin, r...

journal_title：Biochemical and biophysical research communications

authors： McKillop AM,Mooney MH,Harriott P,Flatt PR,O'Harte FP

更新日期：2001-08-24 00:00:00

abstract：:Isolated Agrobacterium tumefaciens was exposed to different extremely low frequencies of square amplitude modulated waves (QAMW) from two generators to determine the resonance frequency that causes growth inhibition. The carrier was 10 MHz sine wave with amplitude ±10 Vpp which was modulated by a second wave generator...

journal_title：Biochemical and biophysical research communications

authors： Fadel MA,El-Gebaly RH,Mohamed SA,Abdelbacki AMM

更新日期：2017-12-09 00:00:00

abstract：:Carp acclimated to 10 degrees C gave 69k, 66k, and 62kDa light meromyosin (LMM) fragments in SDS-PAGE, while fish acclimated to 30 degrees C gave 74k, 69k, 66k, and 62kDa fragments. The microsequence analysis revealed that the 69k and 66kDa components from the 10 degrees C-acclimated carp contained an N-terminal amino...

journal_title：Biochemical and biophysical research communications

authors： Watabe S,Imai J,Nakaya M,Hirayama Y,Okamoto Y,Masaki H,Uozumi T,Hirono I,Aoki T

更新日期：1995-03-08 00:00:00

abstract：:Lamins A, B and C are the major proteins of mammalian nuclear lamina and have been well studied in BHK-21 cells. By synchronizing BHK-21 cells with aphidicolin, a potent inhibitor of DNA alpha-polymerase, we were able to detect a differential pattern of synthesis for nuclear lamins during the cell cycle. Lamin B start...

journal_title：Biochemical and biophysical research communications

authors： Foisy S,Bibor-Hardy V

更新日期：1988-10-14 00:00:00

abstract：:Retinyl ester concentration is regulated by retinoic acid (RA) through an autoregulatory loop, which acts on lecithin:retinol acyltransferase (LRAT). We tested whether retinol esterification activity is downregulated in human mammary carcinoma cells and whether LRAT expression is RAR-regulated. Normal human mammary ep...

journal_title：Biochemical and biophysical research communications

authors： Andreola F,Giandomenico V,Spero R,De Luca LM

更新日期：2000-12-29 00:00:00

abstract：:In RNA, function follows form. Mapping the surface of RNA molecules with chemical and enzymatic probes has revealed invaluable information about structure and folding. Hydroxyl radicals ((·)OH) map the surface of nucleic acids by cutting the backbone where it is accessible to solvent. Recent studies showed that a micr...

journal_title：Biochemical and biophysical research communications

authors： Schlatterer JC,Wieder MS,Jones CD,Pollack L,Brenowitz M

更新日期：2012-08-24 00:00:00

abstract：:Fructose is a key dietary factor in the development of nonalcoholic fatty liver disease (NAFLD). Here we investigated whether WAY-362450 (WAY), a potent synthetic and orally active FXR agonist, protects against fructose-induced steatosis and the underlying mechanisms. C57BL/6J mice, fed 30% fructose for 8 weeks, were ...

journal_title：Biochemical and biophysical research communications

authors： Liu X,Xue R,Ji L,Zhang X,Wu J,Gu J,Zhou M,Chen S

更新日期：2014-07-18 00:00:00

abstract：:A subclone termed as HSG-S8 was previously isolated from human salivary adenocarcinoma cell line, HSG, and proliferated in a serum-free culture. When HSG-S8 and parental HSG cells were transplanted into nude mice i.m. or s.c., both cells reproducibly induced adenocarcinoma. Furthermore, injection of HSG-S8 consistentl...

journal_title：Biochemical and biophysical research communications

authors： Hatakeyama S,Ohara-Nemoto Y,Kyakumoto S,Satoh M

更新日期：1993-02-15 00:00:00

abstract：:DNA cleavage by N-(O,O-diisopropyl)phosphoryl histidine(DIPP-His) is investigated by a submarine agarose electrophoresis technique. It was found that DIPP-His could cleave supercoiled DNAs and lambda DNA without the participation of divalent metal ions, while the histidine itself and N-(O,O-diisopropyl)phosphoryl alan...

journal_title：Biochemical and biophysical research communications

authors： Li Y,Sha YW,Ma Y,Zhao Y

更新日期：1995-08-24 00:00:00

abstract：:A fusion protein comprising the DNA-binding region of the glucocorticoid receptor and the catalytic domain of poly(ADP-ribose) polymerase was constructed. This chimeric protein was expressed both in E. coli and in eukaryotic cells and was recognized by antibodies to both polymerase and the glucocorticoid receptor. Sim...

journal_title：Biochemical and biophysical research communications

authors： Rosenthal D,Hong T,Cherney B,Zhang S,Shima T,Danielsen M,Smulson M

更新日期：1994-07-29 00:00:00

abstract：:Mutations in mitochondrial DNA are one of the important causes of hearing loss. We report here the clinical, genetic, and molecular characterization of two Han Chinese pedigrees with maternally transmitted aminoglycoside-induced and nonsyndromic bilateral hearing loss. Clinical evaluation revealed the wide range of se...

journal_title：Biochemical and biophysical research communications

authors： Yuan H,Chen J,Liu X,Cheng J,Wang X,Yang L,Yang S,Cao J,Kang D,Dai P,Zhai S,Han D,Young WY,Guan MX

更新日期：2007-10-12 00:00:00

abstract：:Odorant binding proteins (OBPs) contribute to the remarkable sensitivity of the insect's olfactory system and play important roles in the olfactory recognition. The orange blossom midge, Sitodiplosis mosellana is a cereal specialist, and utilizes pheromone and host odorant as a cue for its mating and oviposition. Howe...

journal_title：Biochemical and biophysical research communications

authors： Gong ZJ,Miao J,Duan Y,Jiang YL,Li T,Wu YQ

更新日期：2014-02-07 00:00:00

abstract：:The root-knot nematode (RKN) Meloidogyne incognita reproduces on the roots of tobacco (Nicotiana tabacum), damaging crops, reducing crop yield, and causing economic losses annually. The development of resistant genotypes is an alternative strategy to effectively control these losses. However, the molecular mechanism r...

journal_title：Biochemical and biophysical research communications

authors： Xing X,Li X,Zhang M,Wang Y,Liu B,Xi Q,Zhao K,Wu Y,Yang T

更新日期：2017-01-22 00:00:00

abstract：:A neuropeptide was isolated from the corpora cardiaca of the corn earworm moth Heliothis zea, and purified by sequential gradient elution in three reversed phase-high performance liquid chromatographic steps. The primary structure, pGlu-Leu-Thr-Phe-Ser-Ser-Gly-Trp-Gly-Asn-NH2 was determined by automated gas-phase Edma...

journal_title：Biochemical and biophysical research communications

authors： Jaffe H,Raina AK,Riley CT,Fraser BA,Bird TG,Tseng CM,Zhang YS,Hayes DK

更新日期：1988-08-30 00:00:00

abstract：:The effect of HMG1 on the transcriptional block caused by left-handed Z-form in a highly negatively supercoiled DNA was examined using a supercoiled plasmid containing a (CG)10 sequence downstream of promoters. The transcription by E. coli RNA polymerase was blocked at the boundary of alternating CG sequence in the Z-...

journal_title：Biochemical and biophysical research communications

authors： Waga S,Mizuno S,Yoshida M

更新日期：1988-05-31 00:00:00

abstract：:Members of the RNase E/G family are multimeric, 5'-end-sensing, single-strand-specific endoribonucleases that are found in chloroplasts as well as bacteria, and have central roles in RNA processing and degradation. A well-studied member of this family is Escherichia coli RNase G. Recently, we have shown that the inter...

journal_title：Biochemical and biophysical research communications

authors： Jourdan SS,Kime L,McDowall KJ

更新日期：2010-01-01 00:00:00

abstract：:A bioassay based on the measurement of thymidine incorporation into trichloroacetic acid-insoluble materials in erythroid cell suspensions from fetal calf liver was used as the assay for purification of two small peptides (erythrotropins I and II) from fetal calf intestine. The peptides were purified using reversed-ph...

journal_title：Biochemical and biophysical research communications

authors： Congote LF

更新日期：1983-09-15 00:00:00

abstract：:Integrins alpha(M)beta(2) plays important role on leukocytes, such as adhesion, migration, phagocytosis, and apoptosis. It was hypothesized that homomeric associations of integrin subunits provide a driving force for integrins activation, and simultaneously inducing the formation of integrins clusters. However, experi...

journal_title：Biochemical and biophysical research communications

authors： Fu G,Wang C,Wang GY,Chen YZ,He C,Xu ZZ

更新日期：2006-12-29 00:00:00

abstract：:Hydrolysis of polyphosphoinositides by phospholipase C was examined in isolated membranes prepared from [32P]labelled platelets. In the presence of GTP gamma S, thrombin increased the release of inositol triphosphate and inositol biphosphate approximately 500%. GTP gamma S alone stimulated release 2 fold. Maximal acti...

journal_title：Biochemical and biophysical research communications

authors： Baldassare JJ,Fisher GJ

更新日期：1986-06-13 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) have been demonstrated to be intensively involved in the development of various carcinomas, including glioblastoma multiforme (GBM). However, only a few of them have been well characterized. LncRNA CASP5 have been found to be up-regulated in GBM tissues compared with normal tis...

journal_title：Biochemical and biophysical research communications

authors： Zhou Y,Dai W,Wang H,Pan H,Wang Q

更新日期：2018-06-12 00:00:00

abstract：:S-modulin is a 26 kDa protein that regulates light sensitivity of cGMP phosphodiesterase in a Ca(2+)-dependent manner in frog rod outer segments (ROSs). In the present study, we purified S-modulin by taking advantage of a hydrophobic interaction between Phenyl Sepharose and S-modulin at high Ca2+ concentrations. The y...

journal_title：Biochemical and biophysical research communications

authors： Kawamura S,Takamatsu K,Kitamura K

更新日期：1992-07-15 00:00:00

abstract：:The role of hyaluronan binding protein 1 (HABP1) in cell signaling was investigated and in vitro kinase assay demonstrated that it is a substrate for MAP kinase. Phosphorylation of endogenous HABP1 was also observed following treatment of J774 cells with PMA. HABP1 was coimmunoprecipitated with activated ERK, confirmi...

journal_title：Biochemical and biophysical research communications

authors： Majumdar M,Meenakshi J,Goswami SK,Datta K

更新日期：2002-03-08 00:00:00