Abstract:
:At present medical castration employing luteinising hormone releasing hormone (LHRH) agonists is the standard of care for patients with advanced prostate cancer. LHRH agonists suppress the synthesis of testosterone to a castration level. In contrast to surgical castration, medical castration is reversible. However LHRH agonists induce an initial increase of the testosterone level. This so-called testosterone surge leads to tumour growth and increases the disease-specific complaints, known as flare phenomena. It may be possible that the overall survival of these patients is deteriorated. In contrast, gonadotrophin releasing hormone (GnRH) antagonists do not induce a testosterone surge and the level of testosterone decreases as rapidly as that known from a surgical castration.
journal_name
Aktuelle Uroljournal_title
Aktuelle Urologieauthors
Wolff JMdoi
10.1055/s-0028-1098882subject
Has Abstractpub_date
2009-05-01 00:00:00pages
159-63issue
3eissn
0001-7868issn
1438-8820journal_volume
40pub_type
杂志文章,评审abstract::Pain is a cardinal symptom in 70 % of cancer patients. Even in developed countries, 30 to 80 % of these patients are inadequately treated. The main cause for this lack of care is not pain refractory to treatment but inadequate or incorrect use of analgesic drugs. A sufficient treatment of pain requires knowledge of th...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-830208
更新日期:2005-06-01 00:00:00
abstract::The medical profession is a particular health risk. Internal reasons for this are the common practice of self-diagnosis and self-therapy, presenteeism (work despite illness), and increased risks of addiction and suicide. External reasons include infectious diseases, violence against health professionals, the increasin...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0854-5049
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION:Pasqualini's syndrome is an isolated, incretory functional disorder of the testes with a secondary Leydig cell insufficiency but, unlike Klinefelder's syndrome, with normal spermiogenesis and fertility. This unusual form of hypogonadism is caused by an inherent LH secretion disorder of the pituitary gland....
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2006-932206
更新日期:2007-07-01 00:00:00
abstract::Unenhanced computed tomography (CT) has a sensitivity of 97.7 to 100 % for the detection of urolithiasis. Using a modified examination protocol, the radiation exposure of a CT examination can be reduced to the level of a single conventional radiographic view of the abdomen (ultra-low-dose CT), assuming the examination...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2004-830031
更新日期:2004-08-01 00:00:00
abstract::For good reasons, newly detected prostate cancer must not necessarily be treated with curative -intent: Prostate-specific antigen screening leads to overdiagnosis in 54 %. Current international guidelines on the treatment of prostate cancer take this development into account by recommending "active surveillance" (AS) ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0030-1247461
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:We evaluated children with pelvic kidney and their follow-up according to initial renal function and the appearance of concomitant urological pathologies. PATIENTS AND METHODS:In a retrospective analysis of our case notes, we studied 17 children (8 female, 9 male) who had been referred to our department for...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2005-915621
更新日期:2006-07-01 00:00:00
abstract::Between 15 and 20 % of patients diagnosed with renal cell carcinoma suffer from metastatic disease by the time of diagnosis. In addition to systemic therapy, there are various surgical strategies to treat the primary tumour, e. g. cytoreductive nephrectomy (CN) or palliative nephrectomy (PN). In the immunotherapy era,...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0658-0832
更新日期:2018-09-01 00:00:00
abstract::In this narrative review, we give an overview of contemporary conservative treatment concepts for urinary incontinence in female patients. Hereby, we focus on pure stress urinary incontinence, urge incontinence and mixed urinary incontinence. We emphasise the value of rationally used diagnostic methods to be able to d...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-121483
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:In clinical practice the tumour size measured in the histopathological examination of the operative specimen is used both to determine tumour stage. We have investigated the agreement between tumour size determined by preoperative computed tomography (CT) and pathological tumour size. MATERIAL AND METHODS:Betw...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1271392
更新日期:2011-07-01 00:00:00
abstract::Urolithiasis is an urologist's daily business. This article provides an overview of the developments in the management of urinary stone disease since the 1970s. While conventional KUB X-rays and intravenous pyelography were standard imaging procedures in the past, computed tomography is the first choice today. Conserv...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0828-9936
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Partial nephrectomy is the treatment of choice for clinical stage 1 renal tumours. Open partial nephrectomy is the standard operative technique. The use of minimally-invasive strategies such as laparoscopic, robot-assisted partial nephrectomy or laparoendoscopic single site (LESS) partial nephrectomy has inc...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0041-106151
更新日期:2015-11-01 00:00:00
abstract::Transurethral resection of bladder tumors (TURB) is the cornerstone in urological care of bladder cancer patients. Since the introduction of resectoscopes almost 100 years ago, little has changed in the basic resection technique. The further dissemination of the en-bloc resection (ERBT), which in contrast to fragmente...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1171-1137
更新日期:2020-08-01 00:00:00
abstract::With a share of 22.4%, nosocomial urinary tract infections (nUTIs) are among the most frequent infections acquired in hospitals, along with surgical site infections (24.7%), pneumonia (21.5%), clostridium difficile infections (6.6%) and primary sepsis (6%) 1. 80% of all nUTIs are associated with indwelling urinary cat...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-101845
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:Testicular trauma can be classified into blunt or penetrating injury. While every case of penetrating trauma is subjected to surgical treatment, the decision between surgery and conservative treatment must be made for each case of blunt injury. Inspection, palpation and duplex sonography may be helpful in ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-40234
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:Throughout the past years, several studies have shown that fluorescence cystoscopy with ALA (5-aminolevulinic acid) improves the detection rate of superficial bladder tumors by approximately 20 % compared to standard white light cystoscopy. These results suggest a reduced rate of residual/recurrent tumors with ...
journal_title:Aktuelle Urologie
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1055/s-2004-818544
更新日期:2004-11-01 00:00:00
abstract::c-Met plays a significant role in multiple cellular processes. Being encoded by a proto-oncogene, tyrosine kinase supports aggressive tumour behaviour such as tumour invasiveness and formation of metastases. For some subtypes of renal cell carcinoma studies have shown a association between c-Met expression and clinica...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-115401
更新日期:2016-12-01 00:00:00
abstract::Alpha1-receptor blockers (alfuzosin, doxazosin, tamsulosin and terazosin), 5alpha-reductase inhibitors (dutasteride and finasteride) and combinations thereof are used in the drug treatment of benign prostatic syndrome. As before, there is still no evidence supporting the use of plant extracts, the use of anticholinerg...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2006-944297
更新日期:2006-09-01 00:00:00
abstract::The online marketing of physicians must be measured against the same advertising regulations as conventional marketing. In this context, the Medical Professional Code of Conduct, the Medical Products Advertising Act ("Heilmittelwerbegesetz") and the Law against Unfair Competition are particularly relevant. In addition...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-0893-6315
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION:Peritoneal carcinomatosis is a rare finding in metastatic prostate cancer. In the literature peritoneal carcinomatosis is usually reported in its final stages with multiple metastases. A single peritoneal carcinomatosis with no further metastases is a very rare finding. CASE REPORT:We report the case of a...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2007-959185
更新日期:2007-09-01 00:00:00
abstract::Numerous substances are available for the treatment of metastatic renal cell carcinoma (mRCC). Therefore, medical treatment of patients with mRCC has become a very complex subject. This review summarises clinical studies and typical side-effects of currently available agents that have been approved in Germany. The aut...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0972-0788
更新日期:2019-12-01 00:00:00
abstract:INTRODUCTION:In patients with localised renal cell carcinoma, the only curative treatment option is surgical tumour excision. The aim of this study was to evaluate peri- and postoperative outcomes as well as oncologic and functional long-term results following surgical treatment of patients with renal cell carcinoma (p...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0043-118799
更新日期:2020-06-01 00:00:00
abstract::Urinary incontinence is a major problem in elderly patients. Severe underreporting of symptoms in combination with a reluctance of health professionals to ask about continence problems lead to a relevant illness burden. Individual psychological distress and reduction in self-perceived quality of life ending in social ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2005-915613
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:Hematogenous spread of BCG after intravesical instillation against bladder cancer is rare, but may result in systemic infection and hypersensitivity reaction. We investigated fluoroquinolones and steroids in an animal model to improve the therapeutic options in local and systemic BCG infection. Furthermore, we ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-818541
更新日期:2004-09-01 00:00:00
abstract::The prevalence of kidney stones is increasing worldwide. Asymptomatic non-obstructing kidney stones are increasingly detected as an incidental finding on radiologic imaging, which has been performed more frequently over the last decades. Beside the current interventional treatment modalities such as extracorporeal sho...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1559651
更新日期:2015-09-01 00:00:00
abstract::A 19-year-old man complaining of anuria for 1 day was presented. A ureteral stent was indwelled 3 months ago for preventing ureteral obstruction and protecting kidney function. Abdominopelvic computed tomography (CT) scan revealed a solitary pelvic ectopic kidney (PEK) and severe hydronephrosis. And the ureteral stent...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1018-1449
更新日期:2020-03-05 00:00:00
abstract:PURPOSE:The laparoscopic technique is now applied to radical prostatectomy. However, even in laparoscopic prostatectomy, we need a small open wound to remove the prostate from the abdomen. We have developed a modified technique of extraperitoneal laparoscopic radical prostatectomy, exploiting this small open wound as a...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-41602
更新日期:2003-07-01 00:00:00
abstract::The field of urogynaecology represents an interdisciplinary subspecialty which is dedicated to qualified diagnostics and effective treatment of functional, static, endocrine and urological pelvic floor disorders. Core areas of the surgical uro-gynaecology are pelvic floor reconstruction for the treatment of urinary an...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1271571
更新日期:2011-07-01 00:00:00
abstract::Although ureteroarterial fistulas are rare, they result in a high mortality because of the massive urogenital haemorrhage. The diagnosis is often difficult even when invasive measures are applied. Including the ureteroarterial fistula in the diagnostic process in cases of macrohaematuria with a positive medical histor...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0034-1376953
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Percutaneous nephrolithotripsy (PCNL) is one of the main interventional treatment modalities for large kidney stones (> 2 cm diameter). With the implementation of miniaturised techniques the indications for PCNL have been broadened to smaller stones. Especially for urologists without emphasis on endourology ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1555863
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:The optimal treatment options for lower pole stones with a diameter below 15 mm are controversially discussed. Extracorporeal shock wave lithotripsy (ESWL) is non-invasive but is hampered by low stone-free rates and a significant retreatment rate. Flexible ureterorenoscopy (URS) has been demonstrated to have hi...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0029-1224680
更新日期:2009-11-01 00:00:00