Abstract:
:c-Met plays a significant role in multiple cellular processes. Being encoded by a proto-oncogene, tyrosine kinase supports aggressive tumour behaviour such as tumour invasiveness and formation of metastases. For some subtypes of renal cell carcinoma studies have shown a association between c-Met expression and clinical outcome or prognosis. Therefore, c-Met represents a prognostic marker in renal cell carcinoma.Furthermore, c-MET will play a decisive role as a possible target for targeted therapies in the era of personalised medicine. Especially for RCC, the dual inhibition of VEGF and c-MET tyrosine kinase in cases of metastatic, treatment-resistant tumours is gaining clinical relevance. The role of c-Met has not been fully elucidated for all subtypes of renal cell carcinomas. The relevance of c-Met for the remaining subtypes of renal tumours has yet to be clarified.
journal_name
Aktuelle Uroljournal_title
Aktuelle Urologieauthors
Erlmeier F,Weichert W,Autenrieth M,Ivanyi P,Hartmann A,Steffens Sdoi
10.1055/s-0042-115401subject
Has Abstractpub_date
2016-12-01 00:00:00pages
475-479issue
6eissn
0001-7868issn
1438-8820journal_volume
47pub_type
杂志文章,评审abstract::Alpha1-receptor blockers (alfuzosin, doxazosin, tamsulosin and terazosin), 5alpha-reductase inhibitors (dutasteride and finasteride) and combinations thereof are used in the drug treatment of benign prostatic syndrome. As before, there is still no evidence supporting the use of plant extracts, the use of anticholinerg...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2006-944297
更新日期:2006-09-01 00:00:00
abstract::Tomatoes are discussed to have an important role in the prevention of and therapy for prostate cancer (PCA). Whether or not they are also useful in the primary and secondary prevention of benign prostate hyperplasia (BPH) is not clear. This review summarises the results of original contributions with a focus on interv...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1077031
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abstract:INTRODUCTION:Peritoneal carcinomatosis is a rare finding in metastatic prostate cancer. In the literature peritoneal carcinomatosis is usually reported in its final stages with multiple metastases. A single peritoneal carcinomatosis with no further metastases is a very rare finding. CASE REPORT:We report the case of a...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2007-959185
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
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更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION:Hydrocephalus as a complication of tuberculous orchiepididymitis is extremely rare. In this reported case, hydrocephalus was the consequence of a disseminated tuberculous process. CASE REPORT:A 28-year-old man was treated for a left-sided orchiepididymitis. He developed the signs of increased intracranial...
journal_title:Aktuelle Urologie
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0029-1224649
更新日期:2010-01-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-0759-0029
更新日期:2018-12-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-40234
更新日期:2003-05-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0028-1098883
更新日期:2009-05-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0042-103198
更新日期:2016-05-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-104803
更新日期:2016-05-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-121483
更新日期:2018-02-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-108871
更新日期:2016-12-01 00:00:00
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journal_title:Aktuelle Urologie
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doi:10.1055/s-0042-112999
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0041-106151
更新日期:2015-11-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0032-1323744
更新日期:2012-12-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1075-1665
更新日期:2020-04-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2006-932206
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
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更新日期:2018-06-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
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更新日期:2019-12-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1559651
更新日期:2015-09-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-818541
更新日期:2004-09-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1018-1449
更新日期:2020-03-05 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-37558
更新日期:2003-01-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0032-1333239
更新日期:2013-01-01 00:00:00
abstract::With a share of 22.4%, nosocomial urinary tract infections (nUTIs) are among the most frequent infections acquired in hospitals, along with surgical site infections (24.7%), pneumonia (21.5%), clostridium difficile infections (6.6%) and primary sepsis (6%) 1. 80% of all nUTIs are associated with indwelling urinary cat...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-101845
更新日期:2016-05-01 00:00:00
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journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-0893-6315
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION:Ovarian metastases of renal cell cancer (RCC) are extremely rare with less than 20 cases reported to date. These metastases occur in the majority of cases metachronous (i. e. prior to or after identification of the primary tumour) or--such as in our case--synchronous. CASE REPORT:A 42-year-old women was d...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2006-932159
更新日期:2007-01-01 00:00:00