[Current recommendations for the systemic treatment of metastatic renal cell carcinoma].

Abstract:

:Numerous substances are available for the treatment of metastatic renal cell carcinoma (mRCC). Therefore, medical treatment of patients with mRCC has become a very complex subject. This review summarises clinical studies and typical side-effects of currently available agents that have been approved in Germany. The authors give suggestions for the use of these substances in the different therapy lines. :Für die Behandlung des metastasierten Nierenzellkarzinoms steht eine Vielzahl an Medikamenten für die Systemtherapie zur Verfügung. Diese werden sowohl in der Erst- als auch Zweitlinientherapie und in späteren Linien eingesetzt. Die vorliegende Übersichtsarbeit beschreibt die in Deutschland zugelassenen Medikamente der Tyrosinkinase-, mTOR- und Immuncheckpointinhibition für die Systemtherapie des metastasierten klarzelligen Nierenzellkarzinoms und gibt eine Empfehlung für deren klinischen Einsatz aufgrund der vorhanden Phase II- und Phase III-Studiendaten. Des Weiteren werden detailliert die potenziellen Nebenwirkungen der einzelnen Substanzen beschrieben.

journal_name

Aktuelle Urol

journal_title

Aktuelle Urologie

authors

Kröger N,Merseburger AS,Bedke J

doi

10.1055/a-0972-0788

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

606-611

issue

6

eissn

0001-7868

issn

1438-8820

journal_volume

50

pub_type

杂志文章,评审
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    更新日期:2004-09-01 00:00:00

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