Abstract:
PURPOSE:In clinical practice the tumour size measured in the histopathological examination of the operative specimen is used both to determine tumour stage. We have investigated the agreement between tumour size determined by preoperative computed tomography (CT) and pathological tumour size. MATERIAL AND METHODS:Between 2000 and 2007 a total of 444 consecutive patients was diagnosed with a renal tumour and treated operatively at our clinic. A total of 276 patients was eligible and thus included in the study. RESULTS:There were 62% men and 38% women with a median age of 65 years. There were 255 renal cell carcinomas, 7 oncocytomas, 3 angiomyolipomas, and 11 tumours of other histology. Mean tumour size was 65 mm in preoperative radiographic estimates and thereby a mean of 3 mm smaller than the mean pathological tumour size (62 mm, p = 0.0000066). In the radiographic estimate only 67% of the tumours were in the range of a 1 cm size difference of the postoperatively determined tumour size and in only 53% of the cases did the clinical and pathological TNM stages match. In 28/276 cases (10%) the clinical tumour stage was ≥ T2 but the histopathological examination showed a pTNM stage < T2. CONCLUSIONS:Different tomographs as well as observers are probably the main causes for the present results. Standardisation should be established to provide an accurate basis for a differentiated discussion about therapeutic options. This is especially true for low tumour stages where tumour size is the only criterion for staging.
journal_name
Aktuelle Uroljournal_title
Aktuelle Urologieauthors
Frommhold J,Jocham D,Doehn Cdoi
10.1055/s-0031-1271392subject
Has Abstractpub_date
2011-07-01 00:00:00pages
247-51issue
4eissn
0001-7868issn
1438-8820journal_volume
42pub_type
杂志文章abstract::Transurethral resection of bladder tumors (TURB) is the cornerstone in urological care of bladder cancer patients. Since the introduction of resectoscopes almost 100 years ago, little has changed in the basic resection technique. The further dissemination of the en-bloc resection (ERBT), which in contrast to fragmente...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1171-1137
更新日期:2020-08-01 00:00:00
abstract::Faced with the dilemma of choosing between the extremes of standard whole gland therapy and active surveillance, those affected by prostate cancer have recently been on the lookout for less invasive alternatives. Particularly the question of whether it would be possible in low risk cancer to treat only the tumour itse...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1396803
更新日期:2015-01-01 00:00:00
abstract::The precise identification and detection of bladder tumours is a prerequisite for complete transurethral resection and, thus, the reduction of recurrence. White-light cystoscopy remains the gold standard and has been further improved by the introduction of digital HD techniques. New digital techniques such as narrow-b...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0731-0008
更新日期:2019-02-01 00:00:00
abstract::The outpatient forensic aftercare department of the Charité Berlin treated 32 paraphilic sex offenders with GnRH analogues within the past 5 years. Out of those patients, three men suffered from urolithiasis and were in need of treatment. All 3 patients had previously developed osteopenia/osteoporosis while on antiand...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0042-112999
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION:In patients with localised renal cell carcinoma, the only curative treatment option is surgical tumour excision. The aim of this study was to evaluate peri- and postoperative outcomes as well as oncologic and functional long-term results following surgical treatment of patients with renal cell carcinoma (p...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0043-118799
更新日期:2020-06-01 00:00:00
abstract::Pain is a cardinal symptom in 70 % of cancer patients. Even in developed countries, 30 to 80 % of these patients are inadequately treated. The main cause for this lack of care is not pain refractory to treatment but inadequate or incorrect use of analgesic drugs. A sufficient treatment of pain requires knowledge of th...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-830208
更新日期:2005-06-01 00:00:00
abstract::This article reports on the effective and quick treatment of angioceratoma scroti sive vulvae Fordyce using a 940-nm diode laser. Up to now the usage of this laser has not been described for this indication and we show that it provides a successful therapeutic alternative with few side effects. ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1283790
更新日期:2012-03-01 00:00:00
abstract::c-Met plays a significant role in multiple cellular processes. Being encoded by a proto-oncogene, tyrosine kinase supports aggressive tumour behaviour such as tumour invasiveness and formation of metastases. For some subtypes of renal cell carcinoma studies have shown a association between c-Met expression and clinica...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-115401
更新日期:2016-12-01 00:00:00
abstract::Although ureteroarterial fistulas are rare, they result in a high mortality because of the massive urogenital haemorrhage. The diagnosis is often difficult even when invasive measures are applied. Including the ureteroarterial fistula in the diagnostic process in cases of macrohaematuria with a positive medical histor...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0034-1376953
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Hydrocephalus as a complication of tuberculous orchiepididymitis is extremely rare. In this reported case, hydrocephalus was the consequence of a disseminated tuberculous process. CASE REPORT:A 28-year-old man was treated for a left-sided orchiepididymitis. He developed the signs of increased intracranial...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-830255
更新日期:2006-01-01 00:00:00
abstract::Numerous substances are available for the treatment of metastatic renal cell carcinoma (mRCC). Therefore, medical treatment of patients with mRCC has become a very complex subject. This review summarises clinical studies and typical side-effects of currently available agents that have been approved in Germany. The aut...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0972-0788
更新日期:2019-12-01 00:00:00
abstract:INTRODUCTION:Nephron-sparing surgery (NSS) is mandatory for patients with renal tumors in both kidneys or in a solitary kidney in order to preserve renal function (imperative indication). NSS has also become the gold standard (elective indication) for small unilateral renal tumors (< 4 cm) with a normal contralateral k...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0029-1224649
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to prove the efficacy of antegrade sclerotherapy for varicocele testis in patients with azoospermia and in patients with cryptozoospermia (less than 0.1 million spermatozoons/mL ejaculate). We have investigated the induction of spermatogenesis in patients with non-obstructive azoosperm...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2005-915619
更新日期:2006-03-01 00:00:00
abstract::The prevalence of kidney stones is increasing worldwide. Asymptomatic non-obstructing kidney stones are increasingly detected as an incidental finding on radiologic imaging, which has been performed more frequently over the last decades. Beside the current interventional treatment modalities such as extracorporeal sho...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1559651
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Acute epididymitis is an inflammation of the epididymis. It mostly occurs unilaterally and may spread to the testis ('epididymo-orchitis') if untreated. Increasing technological advances allow for an even more detailed examination of concurrent symptoms such as ejaculate changes and the whole spectrum of pat...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-104803
更新日期:2016-05-01 00:00:00
abstract::The treatment of a varicocele in childhood and adolescence is considered very controversial. In the past varicocele was often diagnosed during the medical examination for military purposes, but today varicocele is common in the J1 exam and is found rather frequently. However, we are still lacking evidence-based recomm...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1075-1665
更新日期:2020-04-01 00:00:00
abstract::The medical profession is a particular health risk. Internal reasons for this are the common practice of self-diagnosis and self-therapy, presenteeism (work despite illness), and increased risks of addiction and suicide. External reasons include infectious diseases, violence against health professionals, the increasin...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0854-5049
更新日期:2019-04-01 00:00:00
abstract:MATERIAL AND METHODS:100 consecutive cases after radical prostatectomy with a bacterial count of 10(4) CFU/ml in midstream urine were followed during urological inpatient rehabilitation without antibiotic treatment. Before discharge, a follow-up examination with a urine dipstick and a second urine culture were performe...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0042-103198
更新日期:2016-05-01 00:00:00
abstract::Treatment of a biochemical prostate cancer relapse represents a difficult clinical dilemma, which has remained without a definitive solution so far. Based on clinical studies, we combine radical prostatectomy with extended pelvic lymph node dissection in intermediate and high risk patients as a routine procedure at ou...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0032-1333239
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Hematogenous spread of BCG after intravesical instillation against bladder cancer is rare, but may result in systemic infection and hypersensitivity reaction. We investigated fluoroquinolones and steroids in an animal model to improve the therapeutic options in local and systemic BCG infection. Furthermore, we ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-818541
更新日期:2004-09-01 00:00:00
abstract::In this narrative review, we give an overview of contemporary conservative treatment concepts for urinary incontinence in female patients. Hereby, we focus on pure stress urinary incontinence, urge incontinence and mixed urinary incontinence. We emphasise the value of rationally used diagnostic methods to be able to d...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-121483
更新日期:2018-02-01 00:00:00
abstract::Urinary tract infections (UTI) are amongst the most frequent bacterial infections and therefore responsible for a great amount of antibiotic administration. UTI may present as benign, uncomplicated cystitis or severe, life-threatening urosepsis. Due to the heterogeneity of UTI the European Section of Infections in Uro...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1368176
更新日期:2014-03-01 00:00:00
abstract::Stress urinary incontinence in women is a common problem in Germany, with approx. 5 million women suffering from incontinence symptoms. These numbers are increasing, due to demographic changes; the suspected numbers are even higher. Prior to treatment, an extended diagnostic approach - including urodynamics and cystos...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-121479
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to integrate and validate an additional post-treatment module including improvement and satisfaction scales to the validated German pelvic floor questionnaire. METHODS:The questionnaire contained the domains bladder, bowel prolapse, and sexual symptoms. It was completed by 55 patie...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1271544
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:Ovarian metastases of renal cell cancer (RCC) are extremely rare with less than 20 cases reported to date. These metastases occur in the majority of cases metachronous (i. e. prior to or after identification of the primary tumour) or--such as in our case--synchronous. CASE REPORT:A 42-year-old women was d...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2006-932159
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Partial nephrectomy is the treatment of choice for clinical stage 1 renal tumours. Open partial nephrectomy is the standard operative technique. The use of minimally-invasive strategies such as laparoscopic, robot-assisted partial nephrectomy or laparoendoscopic single site (LESS) partial nephrectomy has inc...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0041-106151
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:In order to assess the efficacy and toxicity of oral estramustine phosphate (EMP) administration, low-dose EMP monotherapy (study 1) and very low-dose EMP therapy with luteinizing hormone-releasing hormone (LH-RH) agonist (study 2) were conducted in previously untreated prostate cancer and long-term outcomes we...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0029-1224657
更新日期:2010-01-01 00:00:00
abstract::Endosalpingiosis of the urinary bladder is a rare benign condition characterised by the presence of ectopic endosalpingeal tissue in the bladder. If histology shows two or more Müllerian-derived components, this condition is referred to as Müllerianosis.To our knowledge less than 20 cases of Müllerianosis and 5 cases ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-110039
更新日期:2018-06-01 00:00:00
abstract::The urethral syndrome with urethral pain and bladder voiding disorders is a diagnosis of exclusion. Possible aetiologies are diverse and include organic, functional and inflammatory pathologies of the urethra. Infections, inflammation of the paraurethral glands, spasms of the sphincter muscle and/or of the pelvic floo...
journal_title:Aktuelle Urologie
pub_type: 评论,杂志文章
doi:10.1055/s-0042-106662
更新日期:2016-08-01 00:00:00
abstract::With a share of 22.4%, nosocomial urinary tract infections (nUTIs) are among the most frequent infections acquired in hospitals, along with surgical site infections (24.7%), pneumonia (21.5%), clostridium difficile infections (6.6%) and primary sepsis (6%) 1. 80% of all nUTIs are associated with indwelling urinary cat...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-101845
更新日期:2016-05-01 00:00:00