Abstract:
:Pain is a cardinal symptom in 70 % of cancer patients. Even in developed countries, 30 to 80 % of these patients are inadequately treated. The main cause for this lack of care is not pain refractory to treatment but inadequate or incorrect use of analgesic drugs. A sufficient treatment of pain requires knowledge of the pathomechanism of pain and of the basics of pain management in cancer patients. The choice of analgesic drugs follows the WHO-recommended increase based on need. As long as possible, analgesic drugs should be given orally following a strict schedule and pre-emptively prior to renewed pain. The non-opioids are a heterogeneous group of drugs with different actions and side effects. Maximum doses exist for this group and weak opioids. A change to strong opioids is indicated when weak opioids fail to achieve sufficient pain control despite titration to the maximum dose. No upper limit exists for strong opioids and their use is limited by the side effects. The most frequent side effects are initial emesis and vomiting as well as long-lasting constipation. For this reason, most patients should be prescribed a temporary antiemetic and a laxative on a permanent basis.
journal_name
Aktuelle Uroljournal_title
Aktuelle Urologieauthors
Weckermann D,Harzmann Rdoi
10.1055/s-2004-830208subject
Has Abstractpub_date
2005-06-01 00:00:00pages
239-44issue
3eissn
0001-7868issn
1438-8820journal_volume
36pub_type
杂志文章abstract:INTRODUCTION:Hydrocephalus as a complication of tuberculous orchiepididymitis is extremely rare. In this reported case, hydrocephalus was the consequence of a disseminated tuberculous process. CASE REPORT:A 28-year-old man was treated for a left-sided orchiepididymitis. He developed the signs of increased intracranial...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2004-830255
更新日期:2006-01-01 00:00:00
abstract::In recent years, PSMA-targeting PET tracers such as 68Ga-PSMA-11 have shown promising results, thus contributing to a better management of prostate cancer patients. At the present time, 68Ga-PSMA-11 is most frequently used for diagnostic evaluation in the setting of biochemical recurrence of prostate cancer. In this c...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-100269
更新日期:2017-04-01 00:00:00
abstract::Urinary incontinence is a major problem in elderly patients. Severe underreporting of symptoms in combination with a reluctance of health professionals to ask about continence problems lead to a relevant illness burden. Individual psychological distress and reduction in self-perceived quality of life ending in social ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2005-915613
更新日期:2005-11-01 00:00:00
abstract::Prostate cancer (PCa) with distant metastasis at diagnosis (M1) is associated with an unfavourable prognosis. Therefore, according to current treatment guidelines, local treatment (radical prostatectomy or irradiation of the prostate gland) is not recommended in men with M1 disease. However, M1 patients inevitably dev...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-113547
更新日期:2016-09-01 00:00:00
abstract::Leiomyomas are benign neoplasms arising from smooth muscle cells. We describe the case of a 17-year-old boy admitted with progressive severe obstructive voiding symptoms. Retrograde urethrography showed a bulbous urethral stricture which was resected with primary urethral anastomosis. Histopathological examination con...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2007-993038
更新日期:2008-03-01 00:00:00
abstract::Although ureteroarterial fistulas are rare, they result in a high mortality because of the massive urogenital haemorrhage. The diagnosis is often difficult even when invasive measures are applied. Including the ureteroarterial fistula in the diagnostic process in cases of macrohaematuria with a positive medical histor...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0034-1376953
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:The laparoscopic technique is now applied to radical prostatectomy. However, even in laparoscopic prostatectomy, we need a small open wound to remove the prostate from the abdomen. We have developed a modified technique of extraperitoneal laparoscopic radical prostatectomy, exploiting this small open wound as a...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-41602
更新日期:2003-07-01 00:00:00
abstract::At present medical castration employing luteinising hormone releasing hormone (LHRH) agonists is the standard of care for patients with advanced prostate cancer. LHRH agonists suppress the synthesis of testosterone to a castration level. In contrast to surgical castration, medical castration is reversible. However LHR...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0028-1098882
更新日期:2009-05-01 00:00:00
abstract::Faced with the dilemma of choosing between the extremes of standard whole gland therapy and active surveillance, those affected by prostate cancer have recently been on the lookout for less invasive alternatives. Particularly the question of whether it would be possible in low risk cancer to treat only the tumour itse...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1396803
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:This systematic review evaluates international data on the medical effectiveness of orchiectomy and medical therapy with LH-RH analogues in patients with advanced prostate cancer. These results are discussed in the context of primary, neoadjuvant, adjuvant and intermittent hormone deprivation. MATERIALS AND ME...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-2008-1038282
更新日期:2008-11-01 00:00:00
abstract::Osteosarcoma of the prostate is a rare finding. These tumours usually occur years after radiotherapy for prostate cancer. We report the case of a 74-year-old man with prostate cancer who had been treated with radiotherapy and androgen deprivation therapy. The man presented with urinary retention and his prostate was t...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0032-1323744
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Gap junctions are intercellular contacts important for the synchronization of muscle cell activity through electrical coupling. Since the role of gap junctions for the function of smooth bladder muscle is still a matter of debate, we investigated the occurrence of gap junctions and the gap junctional protein co...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-42001
更新日期:2003-09-01 00:00:00
abstract::The most exciting data presented at the 2017 ASCO Annual Meeting included the results of the LATITUDE and STAMPEDE trials, which evaluated abiraterone plus prednisone combined with androgen-deprivation therapy (ADT) as a first-line treatment in men with newly diagnosed high-risk metastatic hormone-sensitive prostate c...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0852-3405
更新日期:2019-12-01 00:00:00
abstract::This article reports on the effective and quick treatment of angioceratoma scroti sive vulvae Fordyce using a 940-nm diode laser. Up to now the usage of this laser has not been described for this indication and we show that it provides a successful therapeutic alternative with few side effects. ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1283790
更新日期:2012-03-01 00:00:00
abstract::Pharmacological treatment of BPS is often considered the first therapeutic approach for patients who experience progression in lower urinary tract symptoms (LUTS).α1-adrenoceptor antagonists are often chosen as the first line pharmacological treatment, due to their rapid onset of action, as well as their significant i...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/a-0649-0702
更新日期:2018-08-01 00:00:00
abstract:AIM:The aim of the present study was to evaluate the initiated consecutive diagnostic course after measurement of an elevated PSA value by the general practitioner. PATIENTS AND METHODS:406 patients who underwent ultrasound-guided transrectal biopsy of the prostate were assessed retrospectively. Using a standardised q...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0028-1098883
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:Germ cell differentiation, DNA synthesis, and apoptosis can be evaluated quantitatively. On the other hand, an interstitial lesion is difficult to examine. We have focused on the quantitative analysis of testicular interstitial fibrosis after vasectomy. MATERIALS AND METHODS:Forty testicular biopsy specimens f...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-2003-41612
更新日期:2003-07-01 00:00:00
abstract::Treatment of a biochemical prostate cancer relapse represents a difficult clinical dilemma, which has remained without a definitive solution so far. Based on clinical studies, we combine radical prostatectomy with extended pelvic lymph node dissection in intermediate and high risk patients as a routine procedure at ou...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0032-1333239
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to integrate and validate an additional post-treatment module including improvement and satisfaction scales to the validated German pelvic floor questionnaire. METHODS:The questionnaire contained the domains bladder, bowel prolapse, and sexual symptoms. It was completed by 55 patie...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1271544
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:In order to assess the efficacy and toxicity of oral estramustine phosphate (EMP) administration, low-dose EMP monotherapy (study 1) and very low-dose EMP therapy with luteinizing hormone-releasing hormone (LH-RH) agonist (study 2) were conducted in previously untreated prostate cancer and long-term outcomes we...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0029-1224657
更新日期:2010-01-01 00:00:00
abstract::Testicular and paratesticular cystadenomas arise from an oviduct-like structure, which, morphologically, is almost identical with the ovarian surface epithelium. These are very rare benign tumours of adults. They present as asymptomatic cystic lesions. Bilateral paratesticular cystadenomas are associated with the Von-...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0043-101214
更新日期:2018-06-01 00:00:00
abstract::Urinary tract infections (UTI) are amongst the most frequent bacterial infections and therefore responsible for a great amount of antibiotic administration. UTI may present as benign, uncomplicated cystitis or severe, life-threatening urosepsis. Due to the heterogeneity of UTI the European Section of Infections in Uro...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1368176
更新日期:2014-03-01 00:00:00
abstract::Endosalpingiosis of the urinary bladder is a rare benign condition characterised by the presence of ectopic endosalpingeal tissue in the bladder. If histology shows two or more Müllerian-derived components, this condition is referred to as Müllerianosis.To our knowledge less than 20 cases of Müllerianosis and 5 cases ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0043-110039
更新日期:2018-06-01 00:00:00
abstract::For good reasons, newly detected prostate cancer must not necessarily be treated with curative -intent: Prostate-specific antigen screening leads to overdiagnosis in 54 %. Current international guidelines on the treatment of prostate cancer take this development into account by recommending "active surveillance" (AS) ...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0030-1247461
更新日期:2010-07-01 00:00:00
abstract::The outpatient forensic aftercare department of the Charité Berlin treated 32 paraphilic sex offenders with GnRH analogues within the past 5 years. Out of those patients, three men suffered from urolithiasis and were in need of treatment. All 3 patients had previously developed osteopenia/osteoporosis while on antiand...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0042-112999
更新日期:2016-12-01 00:00:00
abstract::The field of urogynaecology represents an interdisciplinary subspecialty which is dedicated to qualified diagnostics and effective treatment of functional, static, endocrine and urological pelvic floor disorders. Core areas of the surgical uro-gynaecology are pelvic floor reconstruction for the treatment of urinary an...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/s-0031-1271571
更新日期:2011-07-01 00:00:00
abstract::Inguinal bladder hernia accounts for only 1 - 4 % of all inguinal hernias. It may be difficult to diagnose due to the atypical symptoms. In most cases, the diagnosis is only made intraoperatively. However, a preoperative diagnosis is important to avoid possible iatrogenic complications. We report a case series of five...
journal_title:Aktuelle Urologie
pub_type: 杂志文章
doi:10.1055/a-1190-3186
更新日期:2020-06-18 00:00:00
abstract::With a share of 22.4%, nosocomial urinary tract infections (nUTIs) are among the most frequent infections acquired in hospitals, along with surgical site infections (24.7%), pneumonia (21.5%), clostridium difficile infections (6.6%) and primary sepsis (6%) 1. 80% of all nUTIs are associated with indwelling urinary cat...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-101845
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Throughout the past years, several studies have shown that fluorescence cystoscopy with ALA (5-aminolevulinic acid) improves the detection rate of superficial bladder tumors by approximately 20 % compared to standard white light cystoscopy. These results suggest a reduced rate of residual/recurrent tumors with ...
journal_title:Aktuelle Urologie
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1055/s-2004-818544
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Acute epididymitis is an inflammation of the epididymis. It mostly occurs unilaterally and may spread to the testis ('epididymo-orchitis') if untreated. Increasing technological advances allow for an even more detailed examination of concurrent symptoms such as ejaculate changes and the whole spectrum of pat...
journal_title:Aktuelle Urologie
pub_type: 杂志文章,评审
doi:10.1055/s-0042-104803
更新日期:2016-05-01 00:00:00