[Potential for improvement by new resection and imaging techniques in TUR-B].

Abstract:

:Transurethral resection of bladder tumors (TURB) is the cornerstone in urological care of bladder cancer patients. Since the introduction of resectoscopes almost 100 years ago, little has changed in the basic resection technique. The further dissemination of the en-bloc resection (ERBT), which in contrast to fragmented removal preserves the tumor's integrity, might re-adjust the surgical landscape. Benefits attributed to ERBT are better histopathological judgment and higher detrusor muscle rate. In addition, trends for a lower rate of so-called "in-field" recurrences as well as a reduced complication rate have been described. However, randomised, controlled studies with appropriate case numbers and methodology are pending. Few innovations in improved endoscopic tumor diagnostics have been added in recent years. Worth mentioning is the multiparametric magnetic resonance imaging of the bladder, which is intended to improve the accuracy of local tumor propagation compared to conventional imaging alone, as well as techniques in the field of artificial intelligence. The intention of this article is to provide an up-to-date status on EBRT as well as the local diagnostics for urinary bladder tumors. :Die transurethrale Resektion von Harnblasentumoren (TURB) ist ein Grundpfeiler in der urologischen Versorgung von Harnblasenkarzinompatienten. Seit der initialen Einführung von Resektoskopen vor knapp 100 Jahren hat sich an der grundlegenden Resektionstechnik wenig geändert. Erst mit der Verbreitung der sog. En-Bloc-Resektion (ERBT), welche im Gegensatz zur fragmentierten Abtragung die Tumorintegrität erhält, findet eine zögerliche Neujustierung der Technik statt. Vorteile, die der ERBT zugeschrieben werden, sind die bessere histopathologische Beurteilbarkeit und die höhere Detrusormuskulaturrate. Zudem sind Tendenzen für eine geringere Rate an sog. „in-field“ Rezidiven sowie eine verminderte Komplikationsrate beschrieben worden. Randomisierte, kontrollierte Studien mit geeigneter Fallzahl und Methodik stehen allerdings aus. Nur wenige Neuerungen hinsichtlich verbesserter endoskopischer Tumordiagnostik sind in den letzten Jahren hinzugekommen. Erwähnenswert ist die multiparametrische Magnetresonanztomografie der Blase, welche die Genauigkeit der lokalen Tumorausbreitung im Vergleich zur alleinigen konventionellen Bildgebung verbessern soll, sowie Verfahren aus dem Bereich der künstlichen Intelligenz. Die Intention dieses Artikels ist es einen aktuellen Stand über die ERBT sowie die lokale Diagnostik bei Harnblasentumoren zu geben.

journal_name

Aktuelle Urol

journal_title

Aktuelle Urologie

authors

Hennig MJP,Kramer MW

doi

10.1055/a-1171-1137

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

348-352

issue

4

eissn

0001-7868

issn

1438-8820

journal_volume

51

pub_type

杂志文章
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    更新日期:2006-03-01 00:00:00

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    更新日期:2014-03-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:10.1055/s-2004-830031

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    更新日期:2004-08-01 00:00:00

  • [Synchronous bilateral renal cell cancer with a single ovarian metastasis and a fibromuscular dysplasia of the renal artery].

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    doi:10.1055/s-2006-932159

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    更新日期:2007-01-01 00:00:00

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    更新日期:2020-06-18 00:00:00

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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    更新日期:2003-07-01 00:00:00

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    更新日期:2016-08-01 00:00:00

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    abstract::Numerous substances are available for the treatment of metastatic renal cell carcinoma (mRCC). Therefore, medical treatment of patients with mRCC has become a very complex subject. This review summarises clinical studies and typical side-effects of currently available agents that have been approved in Germany. The aut...

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    doi:10.1055/s-2007-993038

    authors: Seseke S,Schweyer S,Reissig K,Seseke F

    更新日期:2008-03-01 00:00:00

  • [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].

    abstract::Patients with metastatic renal cell carcinoma have a life-limiting prognosis. Therefore, the aim of therapy is normally palliative care. Nevertheless, substantial achievements have been made in the past years. Cytokines as long-term standard therapy have been more and more replaced by new targeted therapies. Sunitinib...

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  • [Current Aspects of Epididymo-Orchitis].

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    pub_type: 杂志文章,评审

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  • [Significance and Value of PSMA Ligands in Prostate Cancer].

    abstract::In recent years, PSMA-targeting PET tracers such as 68Ga-PSMA-11 have shown promising results, thus contributing to a better management of prostate cancer patients. At the present time, 68Ga-PSMA-11 is most frequently used for diagnostic evaluation in the setting of biochemical recurrence of prostate cancer. In this c...

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  • [Cancer control in focus insights and future perspectives for the focal treatment of prostate cancer].

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  • [Tuberculous orchiepididymitis and CNS complication].

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    authors: Miletic B,Morovic M,Tomic Z,Ticac B

    更新日期:2006-01-01 00:00:00