GABAergic-serotonergic interactions in regulating lordosis.

abstract：:We examined the contribution of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxalole-4-propionic acid (AMPA)/kainate (KA) receptors to the light-responses of rabbit retinal neurons. In the outer retina, bath application of the AMPA/KA receptor antagonists 6,7-dinitro-quinoxaline-2,3-dione (DNQX) ...

journal_title：Brain research

authors： Cohen ED,Miller RF

更新日期：1999-06-12 00:00:00

abstract：:NMDA receptor activation leads to elevated Ca2+ in cultured rat cortical and retinal ganglion cell neurons. If excessive, this Ca2+ response is associated with delayed neurotoxicity. We used dantrolene and ionomycin to test if the Ca2+ response to NMDA was due to mobilization of intracellular Ca2+ stores rather than m...

journal_title：Brain research

authors： Lei SZ,Zhang D,Abele AE,Lipton SA

更新日期：1992-12-11 00:00:00

abstract：:Reactive oxygen species (ROS) and intrinsic antioxidant defense systems play an important role in both physiological cell signaling processes and many pathological states, including neurodegenerative disorders and oxygen-toxicity. Here we report that short exposures to non-physiologic oxygen levels change the balance ...

journal_title：Brain research

authors： Bendix I,Weichelt U,Strasser K,Serdar M,Endesfelder S,von Haefen C,Heumann R,Ehrkamp A,Felderhoff-Mueser U,Sifringer M

更新日期：2012-11-12 00:00:00

abstract：:Microglial reactivity in the red nucleus of rats was studied following upper cervical and lower thoracic rubrospinal tractotomy using the lectin binding method. Following axotomy, the contralateral nucleus containing the axotomized neurons was identified using the retrograde tracer Fast blue. It was subdivided into do...

journal_title：Brain research

authors： Tseng GF,Wang YJ,Lai QC

更新日期：1996-04-09 00:00:00

abstract：:Rats treated neonatally with pargyline and 5,7-dihydroxytryptamine (5,7-DHT) have an elevated paCO2 and reduced minute ventilation when given 0.7% halothane in oxygen as adults. Serotonin content in the spinal cord of 5,7-DHT treated rats was undetectable and TRH content was reduced by 35%. The 5,7-DHT treated rats we...

journal_title：Brain research

authors： Mueller RA,Towle AC,Breese GR

更新日期：1984-04-30 00:00:00

abstract：:Dopamine-releasing protein (DARP) is a novel factor involved in the function and development of catecholaminergic systems. To test whether a peptide synthesized from the N-terminus of DARP (DARP-36aa) ameliorates deficits in nigrostriatal dopamine, rats were unilaterally lesioned with MPP+, 1 day before administration...

journal_title：Brain research

authors： Phelps SM,Ramirez VD

更新日期：1994-12-12 00:00:00

abstract：:The number of adults in the US affected by bipolar disorder, depression, or schizophrenia is approaching 15 million. Despite decades of research, etiologies of these illnesses remain elusive. Theories of aberrant brain morphology, neurotransmission, and signal conduction have provided the heuristic framework for a lar...

journal_title：Brain research

authors： Maida ME,Hurley SD,Daeschner JA,Moore AH,O'Banion MK

更新日期：2006-08-04 00:00:00

abstract：:Epidemiological studies have shown that steroidal as well as non-steroidal anti-inflammatory drugs lower the risk of developing Alzheimer's Disease (AD). A suppressive effect of these anti-inflammatory drugs on local inflammatory events in AD brains has been suggested, however the mechanisms responsible are still unkn...

journal_title：Brain research

authors： Blom MA,van Twillert MG,de Vries SC,Engels F,Finch CE,Veerhuis R,Eikelenboom P

更新日期：1997-11-28 00:00:00

abstract：:Children with Asperger's Disorder or High Functioning Autism are included in regular education classes but find themselves excluded from the social lives of their classmates. This paper briefly reviews studies which attempt to provide them with training to overcome their social difficulties. These interventions have h...

journal_title：Brain research

authors： Frankel F,Whitham C

更新日期：2011-03-22 00:00:00

abstract：:Hypoxia preconditioning states that a sublethal hypoxia period will afford neuroprotection against a second harmful event. In our experiments, we carried out a procedure for the development of hypoxia preconditioning in adult male Wistar rats using hypoxic exposure (9% O(2); 91% N(2)) for 1 h. The protection against p...

journal_title：Brain research

authors： Rauca C,Zerbe R,Jantze H,Krug M

更新日期：2000-06-16 00:00:00

abstract：:In freely-moving female rats the effects of intraventricular infusion of norepinephrine (NE) on multiunit activity (MUA) were examined in the Diagonal Band of Broca (DBB), medial preoptic area (MPOA) and anterior hypothalamic area (AHA), regions containing neurons producing luteinizing hormone-releasing hormone (LHRH)...

journal_title：Brain research

authors： Leung PC,Whitmoyer DI,Arendash GW,Sawyer CH

更新日期：1981-12-07 00:00:00

abstract：:Previous studies have shown that chronic morphine increases levels of the G-protein subunits Gia and Goa, adenylate cyclase, cyclic AMP-dependent protein kinase, and certain phosphoproteins in the rat locus coeruleus, but not in several other brain regions studied, and that chronic morphine decreases levels of Gia and...

journal_title：Brain research

authors： Terwilliger RZ,Beitner-Johnson D,Sevarino KA,Crain SM,Nestler EJ

更新日期：1991-05-10 00:00:00

abstract：:This work examines the age-related changes of the NO pathway in the central nervous system (CNS), analyzing nitric oxide synthase (NOS) isoform expression, the level of nitrotyrosine-modified proteins, and the NOS activity in the cerebral cortex, decorticated brain (basal ganglia, thalamus, hypothalamus, tegtum and te...

journal_title：Brain research

authors： Siles E,Martínez-Lara E,Cañuelo A,Sánchez M,Hernández R,López-Ramos JC,Del Moral ML,Esteban FJ,Blanco S,Pedrosa JA,Rodrigo J,Peinado MA

更新日期：2002-11-29 00:00:00

abstract：:Amphetamine withdrawal is associated with heightened anxiety-like behavior, which is directly driven by blunted stress-induced glucocorticoid receptor-dependent serotonin release in the ventral hippocampus. This suggests that glucocorticoid availability in the ventral hippocampus during stress may be reduced during am...

journal_title：Brain research

authors： Bray B,Scholl JL,Tu W,Watt MJ,Renner KJ,Forster GL

更新日期：2016-08-01 00:00:00

abstract：:The kinetic properties of the testosterone-metabolizing enzymes were studied in the hypothalamus of adult and young zebra finches of both sexes. Estradiol, 5 alpha-dihydrotestosterone, 5 beta-dihydrotestosterone and 5 beta-androstane-3 alpha,17 beta-diol were identified as metabolites of testosterone in males and fema...

journal_title：Brain research

authors： Vockel A,Pröve E,Balthazart J

更新日期：1988-11-01 00:00:00

abstract：:One of the fundamental tasks of neurobiology is to understand how the precision and specificity of the adult nervous system is achieved during development. This paper reviews the progress that has been made toward this end in studies of the developing mammalian cerebral cortex. Particular attention is focused on the p...

journal_title：Brain research

authors： McConnell SK

更新日期：1988-01-01 00:00:00

abstract：:Neuronal expression of brain-derived neurotrophic factor (BDNF) has been implicated in the mechanism of infarct tolerance (resistance to stroke) (H. Yanamoto et al., Infarct tolerance accompanied enhanced BDNF-like immunoreactivity in neuronal nuclei, submitted to Brain Res.), a process that takes more than 7 days fol...

journal_title：Brain research

authors： Yanamoto H,Nagata I,Sakata M,Zhang Z,Tohnai N,Sakai H,Kikuchi H

更新日期：2000-03-24 00:00:00

abstract：:Fast cyclic voltammetry (FCV) at carbon fibre microelectrodes was used to monitor stimulated noradrenaline (NA) efflux in slices of the ventral part of the rat bed nucleus of stria terminalis (BSTV) superfused with artificial cerebrospinal fluid at 32 degrees C. NA efflux was evoked by local electrical stimulation (tr...

journal_title：Brain research

authors： Palij P,Stamford JA

更新日期：1993-04-02 00:00:00

abstract：:It has been hypothesized that mitochondrial respiratory chain dysfunction leads to a pyrimidine deficiency since the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase is coupled to the electron transport chain. The uridine prodrug triacetyluridine (PN401) is neuroprotective in several models of neurodegenera...

journal_title：Brain research

authors： Garcia RA,Liu L,Hu Z,Gonzalez A,von Borstel RW,Saydoff JA

更新日期：2005-12-20 00:00:00

abstract：:Anisomycin is both a well-established protein synthesis inhibitor and a potent activator of the p38/JNK MAPK pathway. It has been used to block the late phase of long-term potentiation (LTP) and long-term depression (LTD) in hippocampus. In this study, we have found that anisomycin produces a time-dependent decline in...

journal_title：Brain research

authors： Xiong W,Kojic LZ,Zhang L,Prasad SS,Douglas R,Wang Y,Cynader MS

更新日期：2006-04-26 00:00:00

abstract：:The monoamine levels in the locus coeruleus (LC) were determined by HPLC following specific lesions of the ventral mesencephalic tegmental-A10 regions (VMT-A10) and raphé dorsalis (RD). Only lesions in the VMT-A10 area decreased the dopamine (DA) content, which strongly suggests that the projection from this region to...

journal_title：Brain research

authors： McRae-Degueurce A,Milon H

更新日期：1983-03-21 00:00:00

abstract：:Following cholinergic denervation of the hippocampus by medial septal lesions, and unusual neuronal reorganization occurs, in which peripheral sympathetic fibers, originating from the superior cervical ganglia, grow into the hippocampus. Previously, we have found that both hippocampal sympathetic ingrowth (HSI) and ch...

journal_title：Brain research

authors： Harrell LE,Kolasa K,Parsons DS,Ayyagari V

更新日期：1995-04-10 00:00:00

abstract：:The effects of repeated, once daily exposure to either restraint or tail pinch stress on extracellular levels of dopamine in nucleus accumbens and striatum were electrochemically monitored in conscious rats using high-speed chronoamperometry. Acutely, both tail pinch and restraint increased extracellular dopamine leve...

journal_title：Brain research

authors： Doherty MD,Gratton A

更新日期：1992-07-24 00:00:00

abstract：:In the previous study, we reported increased NOS expression in the astrocytes in the spinal cord of the transgenic mice that are used as ALS animal model. In the present study, we performed immunocytochemical studies to investigate the changes of nitrotyrosine-immunoreactivity in the brains of the transgenic mice, and...

journal_title：Brain research

authors： Cha CI,Chung YH,Shin CM,Shin DH,Kim YS,Gurney ME,Lee KW

更新日期：2000-01-17 00:00:00

abstract：:In this study we investigated the functional connectivity in 23 Mild TBI (mTBI) patients with and without memory complaints using resting state fMRI in the sub-acute stage of injury as well as a group of control participants. Results indicate that mTBI patients with memory complaints performed significantly worse than...

journal_title：Brain research

authors： Sours C,Zhuo J,Janowich J,Aarabi B,Shanmuganathan K,Gullapalli RP

更新日期：2013-11-06 00:00:00

abstract：:Maternal separation is known to exert long-term effects on both behavior and the neuroendocrine system. We investigated cocaine-induced locomotor activation as well as the locomotor and corticosterone response to forced novelty in maternally separated adolescent and adult rats. Maternal separation consisted of separat...

journal_title：Brain research

authors： Marin MT,Planeta CS

更新日期：2004-07-02 00:00:00

abstract：:Respiratory neurons were recorded with microelectrodes in the medullary dorsal respiratory group of pentobarbital-anesthetized cats. The animals were ventilated with a phrenic-driven servorespirator that allowed manipulation of phasic volume feedback. By increasing or decreasing the gain of the servorespirator, graded...

journal_title：Brain research

authors： Baker JP Jr,Remmers JE

更新日期：1980-11-03 00:00:00

abstract：:Rab3A is a small GTP-binding synaptic vesicle protein, shown to dissociate from synaptic vesicle membranes upon depolarization-induced exocytosis. Using an antiserum raised against rab3A, we found that the antigen was localized to the neuropil of specific brain regions, but was not present in major fiber tracts or mos...

journal_title：Brain research

authors： Moya KL,Tavitian B,Zahraoui A,Tavitian A

更新日期：1992-09-11 00:00:00

abstract：:We examined the effect of the peripheral application of glutamate and capsaicin to the temporomandibular joint (TMJ) in influencing the activation and central sensitization of TMJ-responsive nociceptive neurons in the trigeminal subnucleus caudalis/upper cervical cord (Vc/UCC). The activity of single neurons activated...

journal_title：Brain research

authors： Lam DK,Sessle BJ,Hu JW

更新日期：2009-02-09 00:00:00

abstract：:We used triple-labeling immunohistochemistry in rat midbrain sections to identify dopaminergic neurons that contain either one or both of the calcium-binding proteins, calretinin (CR) and calbindin-D28k (CB). Midbrain dopaminergic neurons were immunohistochemically labeled for tyrosine hydroxylase (TH), CR, and CB. In...

journal_title：Brain research

authors： Nemoto C,Hida T,Arai R

更新日期：1999-10-30 00:00:00