当前位置： SCI文献检索 > CLINICAL CARDIOLOGY期刊下所有文献 > Prognosis of large, symptomatic pericardial effusion treated by echo-guided percutaneous pericardiocentesis.

Prognosis of large, symptomatic pericardial effusion treated by echo-guided percutaneous pericardiocentesis.

Abstract：

BACKGROUNDS:The causes and prognosis of pericardial effusion (PE) may be different according to time, region, economy, and hospital. This study was performed to evaluate the etiology, clinical outcome, and prognosis of patients with large, symptomatic PE treated by echo-guided pericardiocentesis at Kangnam St. Mary's Hospital (the Catholic University of Korea, Seoul, Korea). HYPOTHESIS:According to etiologies of large, symptomatic PE, the prognosis of patients may be different. METHODS:We reviewed 116 consecutive patients who underwent echo-guided pericardiocentesis due to large, symptomatic PE over the last 12 y. The Kaplan-Meier survival curve with log-rank method was applied for the survival analysis. RESULTS:Procedural success rate of echo-guided pericardiocentesis was 99.1%. Common causes of PE requiring pericardiocentesis were lung cancer (27.6%), tuberculosis (TB) (13.8%), and uremia (6.9%). The mortality rate of 6 mo after the pericardiocentesis was 80.3% in malignant PE, whereas the over-all mortality rate was 18.2% in nonmalignant PE (p < 0.0001). Among the malignant PE, lung cancer (27.6%) and breast cancers (6.9%) were the most common causes. The mean cytologic detection rate and mean life expectancy of malignant PE were 44% and 5-7 mo. Patients with breast cancer and lymphoma had relatively better life expectancy (11.4 and 7.7 mo), whereas those with stomach cancer and metastases of unknown origin (MUO) had poorer prognosis (1.2 and 2.3 mo). The most common causes of nonmalignant PE were TB, uremia, and iatrogenic, and their mean life expectancy was approximately 54 mo. CONCLUSIONS:Malignancy, especially lung cancer and TB, were the most common causes of large symptomatic PE. The prognosis of large symptomatic PE was related to the underlying disease. Malignant PE was associated with the poorest prognosis.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Kil UH,Jung HO,Koh YS,Park HJ,Park CS,Kim PJ,Baek SH,Seung KB,Choi KB

doi

10.1002/clc.20305

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

531-7

issue

eissn

0160-9289

issn

1932-8737

journal_volume

pub_type

杂志文章

在线工具

Prognosis of large, symptomatic pericardial effusion treated by echo-guided percutaneous pericardiocentesis.