Abstract:
BACKGROUND:Atrial fibrillation (AF) is a complex cardiac arrhythmia in clinical practice with increasing incidence. However, the effects of statins on patients with AF are not quite clear. HYPOTHESIS:To investigate the protective effect of calcium channel blocker (CCB) and valsartan combined fluvastatin on hypertension (HTN) patients with nonpermanent AF. METHODS:In three and a half years, 189 cases of patients diagnosed as HTN combining nonpermanent AF by eight medical centers, were recruited and randomly assigned to four groups with varied treatments: CCB group; CCB + statin group; valsartan group; and valsartan + statin group. The four groups were followed up for 24 months. The 7-day Holter ultrasound echocardiography (UCG) and biochemical indexes were completed at preset time nodes respectively. RESULTS:After 24 months of follow-up, 178 patients completed the study. Compared with CCB group, the blood lipid level, inflammatory index, ultrasonic index and electrocardiographic measurement results of CCB + statin group, valsartan group and valsartan + statin group were improved in different degrees and had statistical significance (P < .05 or P < .01). Furthermore, the improvement trend of CCB + statin group and valsartan + statin group was more obvious. CONCLUSIONS:The results indicated that valsartan can reduce AF load and recurrence rate, and delay the progression of nonpermanent AF to permanent AF in multiple ways, and the effect of combination of valsartan and fluvastatin is more significant. These results provide a new direction for the integrated upstream control strategy of AF.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Zhao Z,Yang Y,Wang J,Dong Z,Niu X,Liu E,Liu T,Li L,Liang Y,Li Gdoi
10.1002/clc.23487subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1592-1600issue
12eissn
0160-9289issn
1932-8737journal_volume
43pub_type
杂志文章abstract::Two cases with acute myocardial infarction are presented. Both had thrombotic occlusion of the infarct-related artery. Following successful thrombolysis with streptokinase, coronary angiography was normal. These cases prove that "myocardial infarction with normal coronaries" can be associated with coronary thrombosis ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960061107
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abstract:BACKGROUND:Early reperfusion improves left ventricular (LV) function and survival after acute myocardial infarction (MI). Thrombolytic therapy achieves early patency of the infarct artery in about two-thirds of patients. In nearly half of the remaining patients, in whom early reperfusion was not achieved with thromboly...
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960171114
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abstract:BACKGROUND:Exercise-based rehabilitation is an important part of treatment patients following coronary artery bypass graft (CABG) surgery. HYPOTHESIS:To evaluate effect of very short/short-term exercise training on cardiopulmonary exercise testing (CPET) parameters. METHODS:We studied 54 consecutive patients with myo...
journal_title:Clinical cardiology
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960120508
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abstract::Pregnant patients with mechanical prosthetic heart valves pose a great problem for medical management. The problem is even greater in a pregnant woman with mechanical valve thrombosis. This article describes a pregnant woman with prosthetic mitral valve thrombosis who had a successful fibrinolytic treatment. ...
journal_title:Clinical cardiology
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doi:10.1002/clc.20637
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960130812
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abstract::A 33-year-old man was investigated for dyspnea on exertion and the presence of a pansystolic murmur. Physical examination revealed dextrocardia confirmed by chest radiograph, which also showed oligemic right lung field. Subsequent cardiac catheterization revealed secundum atrial septal defect, persistent left sided su...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960180713
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960210220
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journal_title:Clinical cardiology
pub_type: 杂志文章
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更新日期:2003-09-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4960160703
更新日期:1993-07-01 00:00:00
abstract::The diagnosis of pseudoaneurysm of the ascending aorta is of paramount importance because of its propensity to rupture. As the frequency of surgical procedures involving the aortic root and valve increases, an increase in the incidence of aortic pseudoaneurysm may be anticipated. We recently studied a patient who deve...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960151017
更新日期:1992-10-01 00:00:00
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journal_title:Clinical cardiology
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doi:10.1002/clc.4950260806
更新日期:2003-08-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20664
更新日期:2009-10-01 00:00:00
abstract::While the prevalence of cardiovascular risk factors has decreased in the United States in recent years, cardiovascular disparities by sex and race persist. Among the factors contributing to these disparities is the physical environment in which individuals live. Neighborhood characteristics, ranging from air pollution...
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pub_type: 杂志文章,评审
doi:10.1002/clc.23107
更新日期:2019-01-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章
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更新日期:1985-02-01 00:00:00
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journal_title:Clinical cardiology
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doi:10.1002/clc.4960060709
更新日期:1983-07-01 00:00:00
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更新日期:2010-06-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960110608
更新日期:1988-06-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960050707
更新日期:1982-07-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20060
更新日期:2007-03-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960051008
更新日期:1982-10-01 00:00:00
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journal_title:Clinical cardiology
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更新日期:2016-06-01 00:00:00