Heterogeneity of bla(IND) metallo-beta-lactamase-producing Chryseobacterium indologenes isolates detected in Hefei, China.

abstract：OBJECTIVES:To compare the in vitro activity of linezolid with 12 other antimicrobials against 190 strains of the coryneform bacteria, including 60 strains of C. amycolatum, 30 of C. striatum, 30 of C. jeikeium, 10 of C. urealyticum, 20 of B. casei, 20 of D. hominis and 20 of T. otitidis. METHODS:Minimum inhibitory con...

journal_title：International journal of antimicrobial agents

authors： Gómez-Garcés JL,Alos JI,Tamayo J

更新日期：2007-06-01 00:00:00

abstract：:PCR amplification of 55 strains of Enterobacter cloacae indicated 51 of them had amp C structural gene verified by DNA sequence and Southern blotting. All PCR products were cleaved into 666- and 328-bp fragments by Kpn1 restriction enzyme. Imipenem was the most potent inducer for mRNA expression of amp C gene and beta...

journal_title：International journal of antimicrobial agents

authors： Zhang YL,Li JT,Zhao MW

更新日期：2001-10-01 00:00:00

abstract：:This paper describes the formation of biofilm, its characteristics, its effect on the host cells and treatment of the condition. The airway biofilm diseases are known to be intractable and persistent; also, auto-immune factors play a role in the development of the symptoms. The characteristic of airway biofilm disease...

journal_title：International journal of antimicrobial agents

authors： Kobayashi H

更新日期：2001-05-01 00:00:00

abstract：:Eighty three patients with neutropenia and cancer were randomised to receive either 1 g meropenem tds or amikacin 15 mg/kg single dose daily plus ceftazidime 2 g tds. No prophylactic antibiotics were allowed before entry to the trial. Seventy seven patients were available for analysis. Infection was microbiologically ...

journal_title：International journal of antimicrobial agents

authors： Akova M,Akan H,Korten V,Biberoğlu K,Hayran M,Unal S,Kars A,Kansu E

更新日期：1999-09-01 00:00:00

abstract：:Although cephalosporins are recommended as primary agents, moxifloxacin may be a suitable second-line antibiotic in cardiac surgery, especially if additional Gram-negative coverage is warranted. Cardiopulmonary bypass (CPB) may alter the pharmacokinetics of drugs in numerous ways. Since no such data exist, the aim of ...

journal_title：International journal of antimicrobial agents

authors： Wiesner G,Martin K,Gertler R,Braun SL,Tassani P,Lange R,Gruber M

更新日期：2013-05-01 00:00:00

abstract：:Seven new sites leading to increased beta-lactam susceptibility were identified and mapped in Staphylococcus aureus by Tn551 or Tn917 mediated insertional inactivation. Their effect was more pronounced in methicillin resistant than in susceptible strains. Except for inserts each in SmaI-K and SmaI-B, all were located ...

journal_title：International journal of antimicrobial agents

authors： Vasilieva E,Labischinski H,Berger-Bächi B

更新日期：1997-02-01 00:00:00

abstract：:Recent basic and clinical research efforts have shed more light on the taxonomy, microbiology, epidemiology, antimicrobial susceptibility and treatment of Bacteroides, Prevotella, and Porphyromonas species. Of all anaerobic bacteria, Bacteroides is the most frequently isolated pathogen from clinical specimens, includi...

journal_title：International journal of antimicrobial agents

authors： Falagas ME,Siakavellas E

更新日期：2000-06-01 00:00:00

abstract：:The bacterial time-kill curves of azithromycin against four bacterial strains (Streptococcus pneumoniae/penicillin-intermediate, S. pneumoniae/penicillin-sensitive, Haemophilus influenzae and Moraxella catarrhalis) were determined by in vitro infection models. Eighteen different pharmacokinetic/pharmacodynamic models ...

journal_title：International journal of antimicrobial agents

authors： Treyaprasert W,Schmidt S,Rand KH,Suvanakoot U,Derendorf H

更新日期：2007-03-01 00:00:00

abstract：:In this first multi-centre study in Scotland, 1028 consecutive Gram-negative and staphylococci strains were obtained from four major teaching hospitals. E. coli was the most common organism among both intensive care units (ICUs) (39%) and non-ICU strains (46.6%). The prevalence of antibiotic resistance among E. coli w...

journal_title：International journal of antimicrobial agents

authors： Shanahan PM,Thomson CJ,Miles RS,Old D,Hood J,Gould IM,Amyes SG

更新日期：1996-07-01 00:00:00

abstract：:Gene modifications in the PmrAB and PhoPQ two-component regulatory systems, as well as inactivation of the mgrB gene, are known to be causes of colistin resistance in Klebsiella pneumoniae. The objective of this study was to characterise the mechanism involved in colistin resistance in a Klebsiella oxytoca isolate. A ...

journal_title：International journal of antimicrobial agents

authors： Jayol A,Poirel L,Villegas MV,Nordmann P

更新日期：2015-07-01 00:00:00

abstract：:The proline-rich antimicrobial peptide oncocin is remarkably active in vitro against a number of important Gram-negative bacteria of concern to humans owing to their increasing resistance to antibiotics, i.e. Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenting speci...

journal_title：International journal of antimicrobial agents

authors： Knappe D,Kabankov N,Hoffmann R

更新日期：2011-02-01 00:00:00

abstract：:We evaluated the antimicrobial activity of fusidic acid (CEM-102) against 1140 clinical strains of Gram-positive bacteria obtained from patients with bacteraemia or skin and skin-structure infections collected in more than 30 medical centres in the USA and Canada over a 10-year period (1997-2006). Fusidic acid was ver...

journal_title：International journal of antimicrobial agents

authors： Pfaller MA,Castanheira M,Sader HS,Jones RN

更新日期：2010-03-01 00:00:00

abstract：:Resistance to antimicrobial agents in Gram-positive and Gram-negative bacteria is common in Turkey. In this review, resistance to several antimicrobial agents in this country is discussed for bacteria which have gained clinical importance in recent years. Among Gram-positives, staphylococci are of major importance bec...

journal_title：International journal of antimicrobial agents

authors： Gür D,Unal S,Akalin HE

更新日期：1995-09-01 00:00:00

abstract：:The purpose of this report was to compare two different methods for dose optimisation of antimicrobials. The probability of target attainment (PTA) was calculated using Monte Carlo simulation to predict the PK/PD target of fT>MIC or modelling and simulation of time-kill curve data. Ceftobiprole, the paradigm compound,...

journal_title：International journal of antimicrobial agents

authors： Barbour AM,Schmidt S,Zhuang L,Rand K,Derendorf H

更新日期：2014-01-01 00:00:00

abstract：:The in vitro activity of piperacillin alone or titrated with a constant concentration of 4 mug/ml tazobactam was evaluated against 3962 baseline pathogens isolated from 1899 patients enrolled in 9 clinical trial studies in North America. Tazobactam increased susceptibility rates of piperacillin for Enterobacteriaceae ...

journal_title：International journal of antimicrobial agents

authors： Kuck NA,Jacobus NV,Spengler MD,Testa RT

更新日期：1996-05-01 00:00:00

abstract：:Antimicrobial resistance is a concern both for animal and human health. Veterinary programmes monitoring resistance of animal and zoonotic pathogens are therefore essential. Various European countries have implemented national surveillance programmes, particularly for zoonotic and commensal bacteria, and the European ...

journal_title：International journal of antimicrobial agents

authors： de Jong A,Thomas V,Klein U,Marion H,Moyaert H,Simjee S,Vallé M

更新日期：2013-05-01 00:00:00

abstract：:Wide-spectrum quinolones such as moxifloxacin and levofloxacin as well as high-order cephalosporins such as cefoperazone and cefepime have increased antimicrobial activity. However, little is known about their distribution in fetal blood. Therefore, the aim of this study was to measure and compare maternal and fetal b...

journal_title：International journal of antimicrobial agents

authors： Ozyuncu O,Nemutlu E,Katlan D,Kir S,Beksac MS

更新日期：2010-08-01 00:00:00

abstract：:The in vitro susceptibilities to several antibiotics of 136 Escherichia coli strains containing virulence factors isolated from children with urinary tract infection were analysed. Escherichia coli strains were analysed by multiplex polymerase chain reaction for genes encoding the following virulence factors: pyelonep...

journal_title：International journal of antimicrobial agents

authors： Arisoy M,Rad AY,Akin A,Akar N

更新日期：2008-02-01 00:00:00

abstract：:Fluoroquinolone (FQ) resistance is usually caused by point mutations within the quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC and/or parE. However, little is known about the worldwide increase in FQ-resistant Escherichia coli or, more specifically, about the geographical distribution of QRDR mut...

journal_title：International journal of antimicrobial agents

authors： Uchida Y,Mochimaru T,Morokuma Y,Kiyosuke M,Fujise M,Eto F,Harada Y,Kadowaki M,Shimono N,Kang D

更新日期：2010-04-01 00:00:00

abstract：:Serum bactericidal activity was studied in a crossover manner in 10 volunteers, after 2-day administration of grepafloxacin 600 mg qd, ofloxacin 400 mg bid and clarithromycin 500 mg bid. Bactericidal activity against clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Klebs...

journal_title：International journal of antimicrobial agents

authors： Dan M,Poch F,Asherov J

更新日期：2001-06-01 00:00:00

abstract：:As a follow-up to our 2009 survey, in order to explore opinion and practice on the epidemiology and management of meticillin-resistant Staphylococcus aureus (MRSA) in Europe, we conducted a second survey to elicit current opinions on this topic, particularly around antibiotic choice, dose, duration and route of admini...

journal_title：International journal of antimicrobial agents

authors： Dryden M,Andrasevic AT,Bassetti M,Bouza E,Chastre J,Baguneid M,Esposito S,Giamarellou H,Gyssens I,Nathwani D,Unal S,Voss A,Wilcox M

更新日期：2015-04-24 00:00:00

abstract：:MIC distribution and susceptibility to four antimicrobial agents were determined by E-test for 94 Helicobacter pylori isolates from Costa Rica. Disk diffusion was evaluated as an alternative method to determine susceptibility and compared with the E-test results by linear regression analysis and an error-rate bounded ...

journal_title：International journal of antimicrobial agents

authors： Lang L,García F

更新日期：2004-12-01 00:00:00

abstract：:The characteristics of 218 Klebsiella pneumoniae isolates from patients with hospital-acquired pneumonia in nine Asian countries were investigated. In total, 92 isolates (42.2%) produced extended-spectrum β-lactamases (ESBLs), amongst which 67 (72.8%) possessed CTX-M ESBL genes; CTX-M-15 was the major ESBL (55 isolate...

journal_title：International journal of antimicrobial agents

authors： Lee MY,Ko KS,Kang CI,Chung DR,Peck KR,Song JH

更新日期：2011-08-01 00:00:00

abstract：:Linezolid is an important oxazolidinone antimicrobial for the treatment of infections caused by Gram-positive cocci, especially vancomycin-resistant enterococci and oxacillin-resistant Staphylococcus aureus (ORSA). Since its introduction, however, ribosomal mutations have been detected that produce resistance; thus, l...

journal_title：International journal of antimicrobial agents

authors： Anderegg TR,Sader HS,Fritsche TR,Ross JE,Jones RN

更新日期：2005-07-01 00:00:00

abstract：:Salicylidene acylhydrazide compounds have been shown to inhibit bacterial pathogens, including Chlamydia and Neisseria gonorrhoeae. If such compounds could also target HIV-1, their potential use as topical microbicides to prevent sexually transmitted infections would be considerable. In this study, the in vitro anti-H...

journal_title：International journal of antimicrobial agents

authors： Forthal DN,Phan TB,Slepenkin AV,Landucci G,Chu H,Elofsson M,Peterson E

更新日期：2012-10-01 00:00:00

abstract：:Stenotrophomonas maltophilia and Acinetobacter baumannii are recognised as important nosocomial pathogens; however, due to their intrinsic resistance to multiple antibiotics, treatment options are limited. Polyphenols from black tea have been shown to possess antibacterial action. In this study, the antibacterial effe...

journal_title：International journal of antimicrobial agents

authors： Betts JW,Kelly SM,Haswell SJ

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Since the early 2000s, Escherichia coli resistance to third-generation cephalosporins (3GCs) has been increasing in all European countries, mainly due to the spread of extended spectrum β-lactamases (ESBLs). Here we present a retrospective study that combines resistance of E. coli to 3GCs and quinolones with...

journal_title：International journal of antimicrobial agents

authors： Jeanvoine A,Bouxom H,Leroy J,Gbaguidi-Haore H,Bertrand X,Slekovec C

更新日期：2020-05-01 00:00:00

abstract：:The effect of high-level efflux activity on the MICs of fluoroquinolones against Streptococcus pneumoniae in the absence of topoisomerase mutations leading to fluoroquinolones resistance was investigated. A S. pneumoniae ATCC 46619-derived strain with high-level efflux activity was obtained (SP-25A). Both the parent a...

journal_title：International journal of antimicrobial agents

authors： Daporta MT,Muñoz Bellido JL,Guirao GY,Hernández MS,García-Rodríguez JA

更新日期：2004-08-01 00:00:00

abstract：:Controversy continues regarding whether the presence of meticillin resistance increases mortality risk in Staphylococcus aureus infections. In this study, we assessed the role of meticillin resistance in survival of patients with S. aureus infection included in the EPIC II point-prevalence study of infection in critic...

journal_title：International journal of antimicrobial agents

authors： Hanberger H,Walther S,Leone M,Barie PS,Rello J,Lipman J,Marshall JC,Anzueto A,Sakr Y,Pickkers P,Felleiter P,Engoren M,Vincent JL,EPIC II Group of Investigators.

更新日期：2011-10-01 00:00:00

abstract：:Cystic fibrosis (CF) patients are at risk of acquiring chronic Pseudomonas aeruginosa lung infections. The biofilm mode of growth of P. aeruginosa induces tolerance to antibiotics and the host response; accordingly, treatment failure occurs. Supplemental azithromycin has proven beneficial in CF owing to potential immu...

journal_title：International journal of antimicrobial agents

authors： Thomsen K,Christophersen L,Lerche CJ,Holmgaard DB,Calum H,Høiby N,Moser C

更新日期：2021-01-01 00:00:00