Outcome study of first-episode schizophrenia in a developing country: quality of life and antipsychotics.

Abstract:

AIM:Quality of life has recently been emphasized in the management of schizophrenia, yet data from developing country is lacking. We explored the differences in subjective quality of life between conventional antipsychotics (CAs) and atypical antipsychotics (AAs). METHODS:This is a naturalistic study conducted in Kuala Lumpur, Malaysia. Patients with first-episode schizophrenia and related psychosis were recruited from Kuala Lumpur Hospital. WHOQOL-BREF, side effects of medications and other variables were assessed after 1 year of treatment in routine clinical situation. RESULTS:The study comprised 120 adults. There were no significant statistical differences between groups concerning subjective quality of life, extrapyramidal side effects and employment. Significant less benzhexol usage was reported among AAs (P<0.001) compared to CAs and sulpiride. CONCLUSION:Patients treated with CAs, sulpiride or AAs experienced similar quality of life, clinical and health outcomes after 1 year commencing treatment. Overall, the results are in line with other major pragmatic clinical trials. This study also found sulpiride cost-effective.

authors

Chee KY

doi

10.1007/s00127-008-0415-0

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

143-50

issue

2

eissn

0933-7954

issn

1433-9285

journal_volume

44

pub_type

杂志文章
  • Substances used in deliberate self-poisoning 1985-1997: trends and associations with age, gender, repetition and suicide intent.

    abstract:BACKGROUND:Rates of deliberate self-poisoning have increased in recent years. While over-the-counter availability and prescribing patterns may influence trends in substances used in overdose, these may also be related to clinical characteristics of patients. We investigate trends in substances used for self-poisoning a...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s001270170053

    authors: Townsend E,Hawton K,Harriss L,Bale E,Bond A

    更新日期:2001-05-01 00:00:00

  • Help-seeking behaviours among child psychiatric clinic attenders in Hong Kong.

    abstract::This study employed semi-structured interviews and questionnaires to describe the help-seeking processes and examine the determinants of help-seeking behaviours in 100 consecutive referrals to a child psychiatric clinic in Hong Kong. The help-seeking processes were characterized by (1) a sequential pattern of lay cons...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/BF00787923

    authors: Ho TP,Chung SY

    更新日期:1996-09-01 00:00:00

  • The relationship between social support networks and depression in the 2007 National Survey of Mental Health and Well-being.

    abstract:PURPOSE:Social isolation and low levels of social support are associated with depression. The purpose of the current study was to investigate the relationship between depression and social connectivity factors (frequency of contact and quality of social connections) in the 2007 Australian National Survey of Mental Heal...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-017-1440-7

    authors: Werner-Seidler A,Afzali MH,Chapman C,Sunderland M,Slade T

    更新日期:2017-12-01 00:00:00

  • Spatio-temporal determinants of mental health and well-being: advances in geographically-explicit ecological momentary assessment (GEMA).

    abstract:PURPOSE:Overview of geographically explicit momentary assessment research, applied to the study of mental health and well-being, which allows for cross-validation, extension, and enrichment of research on place and health. METHODS:Building on the historical foundations of both ecological momentary assessment and geogr...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00127-016-1277-5

    authors: Kirchner TR,Shiffman S

    更新日期:2016-09-01 00:00:00

  • Attitudes towards the people with mental illness: comparison between Czech medical doctors and general population.

    abstract:PURPOSE:Stigma among health care professionals is detrimental to the life of those with mental health problems. In the region of post-communist Europe, the level of stigma among health care providers remains understudied. We aimed to compare attitudes towards people with mental illness between Czech medical doctors and...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-016-1263-y

    authors: Winkler P,Mladá K,Janoušková M,Weissová A,Tušková E,Csémy L,Evans-Lacko S

    更新日期:2016-09-01 00:00:00

  • Calculating control variables with age at onset data to adjust for conditions prior to exposure.

    abstract:BACKGROUND:When assessing the association between a factor X and a subsequent outcome Y in observational studies, the question that arises is what are the variables to adjust for to reduce bias due to confounding for causal inference on the effect of X on Y. Disregarding such factors is often a source of overestimation...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-005-0944-8

    authors: Höfler M,Brückl T,Lieb R,Wittchen HU

    更新日期:2005-09-01 00:00:00

  • Young adults' relationship transitions and the incidence of mental disorders: a three-wave longitudinal study.

    abstract:BACKGROUND:Relationship transitions have consistently been found to be associated with mental health in young adulthood, but previous studies have not demonstrated clearly whether such relationship transitions actually precede the development of mental health problems and have focused almost exclusively on subclinical ...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-003-0689-1

    authors: Overbeek G,Vollebergh W,Engels RC,Meeus W

    更新日期:2003-12-01 00:00:00

  • Compulsory admission of mentally ill patients in European Union Member States.

    abstract:BACKGROUND AND AIMS:A standardised and systematic analysis of commitment laws in the European Union Member States is still missing. This study aimed at gathering, describing and analysing information on the differences or similarities of legal frameworks for involuntary placement and treatment of mentally ill patients ...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-004-0814-9

    authors: Dressing H,Salize HJ

    更新日期:2004-10-01 00:00:00

  • Associations between perceived neighborhood environment and cognitive function among middle-aged and older women and men: Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.

    abstract:PURPOSE:To examine cross-sectional associations between perceived neighborhood environment and cognitive function among middle-aged and older Hispanic/Latino women and men. METHODS:Data from the Hispanic Community Health Study/Study of Latinos (2008-2011) and its Sociocultural Ancillary Study (2009-2010) were used. Pa...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-019-01829-0

    authors: Estrella ML,Durazo-Arvizu RA,Gallo LC,Isasi CR,Perreira KM,Vu TT,Vasquez E,Sachdeva S,Zeng D,Llabre MM,Tarraf W,González HM,Daviglus ML,Lamar M

    更新日期:2020-06-01 00:00:00

  • The role of self-report questionnaire in the screening of postnatal depression- a community sample survey in central Tokyo.

    abstract:BACKGROUND:Numerous studies have shown that health care professionals often experience difficulty in detecting postnatal depression. In Japan, where mental illness has traditionally been stigmatized, detection seems even more difficult. This study investigates the prevalence of postnatal depression in the community and...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-004-0727-7

    authors: Nishizono-Maher A,Kishimoto J,Yoshida H,Urayama K,Miyato M,Otsuka Y,Matsui H

    更新日期:2004-03-01 00:00:00

  • Asian Americans and European Americans' stigma levels in response to biological and social explanations of depression.

    abstract:INTRODUCTION:Mental illness stigma is prevalent among Asian Americans, and it is a key barrier that prevents them from seeking psychological services. Limited studies have experimentally examined how Asian Americans respond to biological and social explanations of mental illness. Understanding how to educate and commun...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-014-0999-5

    authors: Cheng ZH

    更新日期:2015-05-01 00:00:00

  • Gambling involvement and problem gambling correlates among European adolescents: results from the European Network for Addictive Behavior study.

    abstract:PURPOSE:Worldwide, concern has grown over the expansion of gambling among adolescents, who have an increased likelihood of developing risk-taking behaviors. This study aimed to increase knowledge of problem gambling among adolescents in seven European countries and to assess the effect of demographic and lifestyle fact...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-019-01706-w

    authors: Andrie EK,Tzavara CK,Tzavela E,Richardson C,Greydanus D,Tsolia M,Tsitsika AK

    更新日期:2019-11-01 00:00:00

  • How ubiquitous are physical and psychological complaints in young and middle adulthood? A longitudinal perspective.

    abstract:OBJECTIVES:To investigate continuity and change of self-reported physical and psychological complaints in young adults over a period of 20 years. STUDY DESIGN AND SETTING:The Zurich Study--a long-term panel survey in psychiatric epidemiology--is based on a stratified sample of 591 subjects born in 1958 (women) and 195...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-006-0111-x

    authors: Ajdacic-Gross V,Horvath S,Canjuga M,Gamma A,Angst J,Rössler W,Eich D

    更新日期:2006-11-01 00:00:00

  • Life events: children's reports.

    abstract::Children 7 to 12 years of age were asked to indicate events they had experienced in the previous three months in a questionnaire devised for the study. Most children were able to complete the questionnaire and reported positive and negative events, the most common themes being personal achievement, illness-related eve...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/BF00782882

    authors: Bailey D,Garralda ME

    更新日期:1990-11-01 00:00:00

  • Perceptions of a South African schizophrenia population with regards to community attitudes towards their illness.

    abstract:BACKGROUND:With the worldwide shift towards a more community-based psychiatric service delivery approach, stigma and the issues surrounding it have received much attention. However, very little South African data exist and the aim of our study was therefore to investigate the experience of internalized stigma in a Sout...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-006-0071-1

    authors: Botha UA,Koen L,Niehaus DJ

    更新日期:2006-08-01 00:00:00

  • Association between financial strain, social network and five-year recovery from first episode psychosis.

    abstract::Despite much effort to positively affect long-term outcome in psychosis and schizophrenia many patients are still facing a poor outcome with persistent psychotic symptoms and decline in social functioning. The aim of this study was to examine the relationship between financial strain and social network and five-year o...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-008-0392-3

    authors: Mattsson M,Topor A,Cullberg J,Forsell Y

    更新日期:2008-12-01 00:00:00

  • Self-labeling as having a mental or physical illness: the effects of stigma and implications for help-seeking.

    abstract:PURPOSE:Personal and perceived stigma can hinder persons in appraising their symptoms as constituting part of a mental illness (self-labeling), an important early step in the help-seeking process. This study examines the impact of personal and perceived stigma on self-labeling and provides prospective data on the possi...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-019-01787-7

    authors: Horsfield P,Stolzenburg S,Hahm S,Tomczyk S,Muehlan H,Schmidt S,Schomerus G

    更新日期:2020-07-01 00:00:00

  • Relationship of social factors including trust, control over life decisions, problems with transport and safety, to psychological distress in the community.

    abstract:PURPOSE:Psychological distress encompasses anxiety and depression with the previous studies showing that psychological distress is unequally distributed across population groups. This paper explores the mechanisms and processes which may affect the distribution of psychological distress, including a range of individual...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-011-0354-z

    authors: Taylor AW,Chittleborough C,Gill TK,Winefield H,Baum F,Hiller JE,Goldney R,Tucker G,Hugo G

    更新日期:2012-03-01 00:00:00

  • Physical, sexual and social health factors associated with the trajectories of maternal depressive symptoms from pregnancy to 4 years postpartum.

    abstract:PURPOSE:Few studies have examined the course of maternal depressive across pregnancy and early parenthood. The aim of this study was to identify the physical, sexual and social health factors associated with the trajectories of maternal depressive symptoms from pregnancy to 4 years postpartum. METHOD:Data were drawn f...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-017-1387-8

    authors: Giallo R,Pilkington P,McDonald E,Gartland D,Woolhouse H,Brown S

    更新日期:2017-07-01 00:00:00

  • Links between social class and common mental disorders in Northeast Brazil.

    abstract:BACKGROUND:Social class is an important aspect of all societies. Social class differences in the prevalence of common mental disorder are likely to vary according to time, culture and stage of economic development. The present study aimed to investigate the intermediaries between social class and common mental disorder...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s001270050297

    authors: Ludermir AB,Lewis G

    更新日期:2001-03-01 00:00:00

  • Sex differences in depression after widowhood. Do men suffer more?

    abstract:BACKGROUND:This study focuses on sex differences in depression of the widowed. Previous research showed different results in sex differences and in depression after bereavement. We assessed the effects of widowhood on depressive symptoms for men and women and examined whether environmental strain like social support, f...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s001270050160

    authors: van Grootheest DS,Beekman AT,Broese van Groenou MI,Deeg DJ

    更新日期:1999-07-01 00:00:00

  • Traumatic events and their relative PTSD burden in Northern Ireland: a consideration of the impact of the 'Troubles'.

    abstract:PURPOSE:Over a 30-year period in its recent history, daily life in Northern Ireland (NI) was characterised by civil violence, colloquially termed as the 'Troubles'. The current report examines exposure to 29 traumatic event types and the associated conditional prevalence of post-traumatic stress disorder (PTSD) among t...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-013-0757-0

    authors: Ferry F,Bunting B,Murphy S,O'Neill S,Stein D,Koenen K

    更新日期:2014-03-01 00:00:00

  • Assessment of physical etiologies for mood and anxiety disorders in structured diagnostic interviews.

    abstract:BACKGROUND:Structured diagnostic inter- views include items that evaluate physical etiologies for mood and anxiety disorders. The objective of this article was to assess the impact of such items. METHOD:A mental health survey in Canada collected data from n = 36,984 household residents. The lifetime prevalence of mood...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-007-0195-y

    authors: Patten SB,Williams JV

    更新日期:2007-06-01 00:00:00

  • Results of a screening survey for co-morbid substance misuse amongst patients in treatment for psychotic disorders: prevalence and service needs in an inner London borough.

    abstract:BACKGROUND:There is great concern in the UK, and other countries, about the clinical management of psychosis and substance misuse co-morbidity. However, relatively little is known about the UK prevalence and management of co-morbidity. METHOD:We implemented a screening survey of patients who were in treatment with an ...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s001270170030

    authors: Weaver T,Rutter D,Madden P,Ward J,Stimson G,Renton A

    更新日期:2001-08-01 00:00:00

  • Social reactions of Swedish and Turkish adolescents to a close friend's suicidal disclosure.

    abstract:BACKGROUND:The prevalence of nonfatal suicidal behavior has been shown to be equal in Swedish and Turkish adolescents, but more Swedish than Turkish adolescents kill themselves. Social attitudes towards self-killing are liberal/permissive in Sweden compared to condemnatory/prohibiting attitudes in Turkey. Against this ...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s001270050225

    authors: Eskin M

    更新日期:1999-09-01 00:00:00

  • Variability in clinical diagnoses during the ICD-8 and ICD-10 era.

    abstract:AIMS:To explore whether the diagnostic homogeneity in a daily, routine clinical activity changed visibly over two historical periods (the ICD-8 and the ICD-10 era) across and within five psychiatric in-patient clinics. METHODS:In this register study, we analyzed the discharge diagnoses from five university-affiliated ...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-016-1265-9

    authors: Nordgaard J,Jessen K,Sæbye D,Parnas J

    更新日期:2016-09-01 00:00:00

  • Sexual orientation disparities in the co-occurrence of substance use and psychological distress: a national population-based study (2008-2015).

    abstract:PURPOSE:Although strong evidence documents the elevated prevalence of both substance use and mental health problems among sexual minorities (i.e., gay, lesbian, and bisexuals), relatively less research has examined whether risk of the co-occurrence of these factors is elevated among sexual minorities compared to hetero...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-018-1491-4

    authors: Bränström R,Pachankis JE

    更新日期:2018-04-01 00:00:00

  • Stigma and disclosing one's mental illness to family and friends.

    abstract:PURPOSE:People with mental illness face the dilemma whether or not to disclose their condition. We examined stigma variables and their relationship with comfort disclosing. METHODS:Comfort with disclosure, well-being, symptoms and aspects of experiencing and reacting to stigma were assessed among 202 individuals with ...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s00127-014-0871-7

    authors: Rüsch N,Brohan E,Gabbidon J,Thornicroft G,Clement S

    更新日期:2014-07-01 00:00:00

  • A systematic review and meta-analysis of the ethnic density effect in psychotic disorders.

    abstract:PURPOSE:A number of studies have found an ethnic density effect in psychotic disorders, where the incidence for ethnic minorities increases as the neighbourhood proportional ethnic composition decreases [Morgan and Hutchinson, Psychol Med 40:705-709, (2010); Singh, Psychol Med 39:1402-1403, (2009); Schofield et al., Ps...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00127-013-0773-0

    authors: Bosqui TJ,Hoy K,Shannon C

    更新日期:2014-04-01 00:00:00

  • Parental rearing and problem behaviours in male delinquent adolescents versus controls in northern Russia.

    abstract::The purpose of this study was to investigate possible relationships between parental rearing practices and problem behaviours in a sample of male delinquent adolescents versus controls. A total of 133 subjects from a juvenile correction centre and 108 matched school-children in the Arkhangelsk region, Russia, were ass...

    journal_title:Social psychiatry and psychiatric epidemiology

    pub_type: 杂志文章

    doi:10.1007/s001270050082

    authors: Ruchkin VV,Eisemann M,Hägglöf B

    更新日期:1998-10-01 00:00:00