当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS期刊下所有文献 > Quinolones in the treatment of complicated urinary tract infection.

Quinolones in the treatment of complicated urinary tract infection.

Abstract：

:Complicated and recurrent urinary tract infections present intriguing clinical management problems. The underlying conditions in patients with complicated urinary tract infections are anatomical abnormalities of the genitourinary tract, neurologic disorders resulting in urinary stasis, obstruction, instrumentation, surgery, diabeters mellitus, renal transplantation, and renal calculi. In comparative studies the quinolones have been shown to be effective in 7-14-day treatment courses in complicated urinary tract infection. Several comparative trials which compare the fluoroquinolones with beta-lactam antibiotics or cotrimoxazole yielded equal or better results for the quinolones. A cost-saving option is given with some of the fluoroquinolones that can be administered parenterally and orally which enables the patient to be discharged from the hospital earlier. There are few differences in antimicrobial activity between the newer quinolones, but differences in the pharmacokinetic properties are evident. The fluoroquinolones are suitable therapeutics for complicated urinary tract infection, because they offer rapid oral absorption, high tissue concentration, broad activity against most Gram-negative and Gram-positive organisms, the possibility of a once-a-day administration, and relatively few side effects.

journal_name

Int J Antimicrob Agents

journal_title

International journal of antimicrobial agents

authors

Graninger W,Wenisch C,Presterl E

doi

10.1016/0924-8579(94)90019-1

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

S29-37

eissn

0924-8579

issn

1872-7913

pii

0924-8579(94)90019-1

journal_volume

4 Suppl 2

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS文献大全
  • Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials.

    abstract：BACKGROUND:Fluoroquinolones (FQs) are second-line antimicrobial agents. Once the decision to prescribe an antimicrobial is made, the choice of antimicrobial should be based on both the benefits and adverse effects. This systematic review quantifies the occurrence of common adverse events (AEs) related to FQs in relatio...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ijantimicag.2018.04.014

    authors： Tandan M,Cormican M,Vellinga A

    更新日期：2018-11-01 00:00:00

  • Susceptibility to five antifungals of Aspergillus fumigatus strains isolated from chronically colonised cystic fibrosis patients receiving azole therapy.

    abstract：:Exposure of Aspergillus fumigatus to stressful antifungal therapies may result in decreased susceptibility. The aim of the present work was to evaluate the susceptibility to azole and non-azole antifungals of 159 isolates of A. fumigatus collected from cystic fibrosis (CF) patients receiving azole antifungal therapy. ...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2009.12.007

    authors： Amorim A,Guedes-Vaz L,Araujo R

    更新日期：2010-04-01 00:00:00

  • In vitro and in vivo evaluation of fluoroquinolone resistance associated with DNA gyrase mutations in Francisella tularensis, including in tularaemia patients with treatment failure.

    abstract：:Fluoroquinolones (FQs) are highly effective for treating tularaemia, a zoonosis caused by Francisella tularensis, but failures and relapses remain common in patients with treatment delay or immunocompromised status. FQ-resistant strains of F. tularensis harboring mutations in the quinolone-resistance determining regio...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2017.03.022

    authors： Sutera V,Hoarau G,Renesto P,Caspar Y,Maurin M

    更新日期：2017-09-01 00:00:00

  • Antifungal activities of azole agents against the Malassezia species.

    abstract：:In this paper, we identified 95 Malassezia isolates by morphological and biochemical criteria and assessed the in vitro activity of fluconazole, itraconazole, ketoconazole and voriconazole by broth microdilution against these species using slightly modified Leeming-Notman medium. The Malassezia isolates were identifie...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2006.09.016

    authors： Miranda KC,de Araujo CR,Costa CR,Passos XS,de Fátima Lisboa Fernandes O,do Rosário Rodrigues Silva M

    更新日期：2007-03-01 00:00:00

  • Effects of low, subinhibitory concentrations of antibiotics on expression of a virulence gene cluster of pathogenic Escherichia coli by using a wild-type gene fusion.

    abstract：:S fimbrial adhesins (Sfa) represent virulence factors of E. coli wild-type strains causing urinary tract infections and meningitis of the new born. In order to determine the influence of subinhibitory concentration of antibiotics on the expression of the sfa gene cluster, a wild-type strain carrying the lacZ gene, cod...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/0924-8579(93)90060-i

    authors： Hacker J,Ott M,Hof H

    更新日期：1993-01-01 00:00:00

  • In vitro activity of clarithromycin in combination with other antimicrobial agents against Mycobacterium abscessus and Mycobacterium massiliense.

    abstract：:Macrolides, especially clarithromycin (CLA), remain the cornerstone of therapy for Mycobacterium abscessus complex infections. The purpose of this study was to gather results from in vitro drug susceptibility testing of M. abscessus and Mycobacterium massiliense for the combination of CLA with various other agents, in...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2016.12.003

    authors： Zhang Z,Lu J,Liu M,Wang Y,Zhao Y,Pang Y

    更新日期：2017-03-01 00:00:00

  • Emergence of colistin resistance in Pseudomonas aeruginosa ST235 clone in South Korea.

    abstract：:In this study, the prevalence and characteristics of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa isolates in South Korea were investigated. Among 215 P. aeruginosa isolates collected from eight hospitals, 77 (35.8%) and 72 (33.5%) were resistant to imipenem and meropenem, respectively. Of the 77 imipene...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2017.01.023

    authors： Wi YM,Choi JY,Lee JY,Kang CI,Chung DR,Peck KR,Song JH,Ko KS

    更新日期：2017-06-01 00:00:00

  • Bactericidal oncocin derivatives with superior serum stabilities.

    abstract：:The proline-rich antimicrobial peptide oncocin is remarkably active in vitro against a number of important Gram-negative bacteria of concern to humans owing to their increasing resistance to antibiotics, i.e. Enterobacteriaceae (Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae) and non-fermenting speci...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2010.10.028

    authors： Knappe D,Kabankov N,Hoffmann R

    更新日期：2011-02-01 00:00:00

  • Efficacy of anidulafungin, caspofungin and fluconazole in the early phase of infection in a neutropenic murine invasive candidiasis model.

    abstract：:In this study, we investigated the in vivo efficacy of anidulafungin during the early phase of disseminated candidiasis in a neutropenic murine model and compared the results with those obtained for fluconazole. Antifungal efficacy was evaluated by reduction of fungal burden in the tissues of infected animals at perio...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2010.02.020

    authors： Krishnan-Natesan S,Manavathu EK,Cutright JL,Chandrasekar PH

    更新日期：2010-07-01 00:00:00

  • Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests.

    abstract：:The antibacterial effects of six inorganic antibacterial agents were assessed using broth dilution and agar dilution tests on six pathogenic bacteria associated with oral infectious diseases: Streptococcus mutans (ATCC 25175), S. mutans (Ingbritt), Actinomyces viscosus (ATCC 15987), Lactobacillus casei (ATCC 393), Sta...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2006.01.008

    authors： Fang M,Chen JH,Xu XL,Yang PH,Hildebrand HF

    更新日期：2006-06-01 00:00:00

  • Transcriptional profiling of the two-component regulatory system VraSR in Staphylococcus aureus with low-level vancomycin resistance.

    abstract：:The objective of this study was to comprehensively identify the target genes regulated by the two-component regulatory system VraSR in Staphylococcus aureus and to clarify the role of VraSR in low-level vancomycin resistance. Expression of vraS was determined by real-time quantitative reverse transcriptase PCR (qRT-PC...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2016.02.003

    authors： Chen H,Xiong Z,Liu K,Li S,Wang R,Wang X,Zhang Y,Wang H

    更新日期：2016-05-01 00:00:00

  • Wide distribution of CC92 carbapenem-resistant and OXA-23-producing Acinetobacter baumannii in multiple provinces of China.

    abstract：:Carbapenem-resistant Acinetobacter baumannii has spread rapidly across China and is currently reported to be a worldwide nosocomial menace. In light of its increasing clinical significance, this study aimed to investigate the molecular epidemiology of carbapenem-resistant and carbapenem-susceptible isolates obtained f...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2013.06.019

    authors： Ruan Z,Chen Y,Jiang Y,Zhou H,Zhou Z,Fu Y,Wang H,Wang Y,Yu Y

    更新日期：2013-10-01 00:00:00

  • Susceptibility of lactic acid bacteria, bifidobacteria and other bacteria of intestinal origin to chemotherapeutic agents.

    abstract：:Chemotherapy is a cornerstone of cancer treatment but it can have serious side effects, such as intestinal mucositis. This work reports the susceptibility/resistance profiles of 34 species of lactic acid bacteria (LAB), bifidobacteria and other intestinal bacteria from different collections to various chemotherapeutic...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2016.07.011

    authors： Flórez AB,Sierra M,Ruas-Madiedo P,Mayo B

    更新日期：2016-11-01 00:00:00

  • Genetic diversity of Streptococcus pneumoniae in Tunisia.

    abstract：OBJECTIVES:This study aimed to explore the genetic diversity of Streptococcus pneumoniae isolates in a Tunisian pneumology hospital. METHODS:A total of 141 S. pneumoniae strains isolated between 2009-2016 in the microbiology laboratory at A. Mami Hospital of Pneumology were investigated. Antimicrobial susceptibility t...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2018.09.023

    authors： Midouni B,Mehiri E,Ghariani A,Draoui H,Essalah L,Bouzouita I,Raoult D,Slim-Saidi L,Fournier PE

    更新日期：2019-01-01 00:00:00

  • Use of colistin-containing products within the European Union and European Economic Area (EU/EEA): development of resistance in animals and possible impact on human and animal health.

    abstract：:Since its introduction in the 1950s, colistin has been used mainly as a topical treatment in human medicine owing to its toxicity when given systemically. Sixty years later, colistin is being used as a last-resort drug to treat infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa, Acinetobacter bauman...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijantimicag.2015.06.005

    authors： Catry B,Cavaleri M,Baptiste K,Grave K,Grein K,Holm A,Jukes H,Liebana E,Lopez Navas A,Mackay D,Magiorakos AP,Moreno Romo MA,Moulin G,Muñoz Madero C,Matias Ferreira Pomba MC,Powell M,Pyörälä S,Rantala M,Ružauskas M,Sa

    更新日期：2015-09-01 00:00:00

  • Susceptibility and resistance genes to fluoroquinolones in methicillin-resistant Staphylococcus aureus isolated in 2002.

    abstract：:The activity of six fluoroquinolones (FQs) was determined against 100 methicillin-resistant Staphylococcus aureus (MRSA) isolated in 2002 along with mutations in the grlA and gyrA genes and in the norA promoter of these isolates. Of the isolates tested, 97% had mutations in grlA and gyrA. A single mutation in grlA and...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2004.11.016

    authors： Noguchi N,Okihara T,Namiki Y,Kumaki Y,Yamanaka Y,Koyama M,Wakasugi K,Sasatsu M

    更新日期：2005-05-01 00:00:00

  • Differences in the evolution of imipenem susceptibility among Klebsiella pneumoniae and Escherichia coli isolates during a 6-year period in a tertiary care hospital.

    abstract：:The evolution of imipenem disk-diffusion susceptibility results of 2652 strains of Klebsiella pneumoniae and 7596 Escherichia coli isolated during the period 2000-2005 were analysed. Screening for production of metallo-beta-lactamases was performed using the EDTA-synergy method. The percentage rate of K. pneumoniae is...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2006.09.010

    authors： Papaparaskevas J,Pantazatou A,Stefanou I,Mela V,Galatidis N,Avlamis A

    更新日期：2007-02-01 00:00:00

  • Ceftaroline fosamil as a potential treatment option for Staphylococcus aureus community-acquired pneumonia in adults.

    abstract：:Staphylococcus aureus (S. aureus), including methicillin-resistant S. aureus (MRSA), is an important aetiological cause of community-acquired pneumonia (CAP) and associated with significant morbidity and mortality. Empiric therapy for CAP frequently consists of β-lactam monotherapy or β-lactam/macrolide combination th...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijantimicag.2019.08.012

    authors： Welte T,Kantecki M,Stone GG,Hammond J

    更新日期：2019-10-01 00:00:00

  • Green tea inhibits Helicobacter growth in vivo and in vitro.

    abstract：:Helicobacter infection, one of the most common bacterial infections in man worldwide, is a type 1 carcinogen and the most important risk factor for gastric cancer. Helicobacter pylori bacterial factors, components of the host genetics and immune response, dietary cofactors and decreased acid secretion resulting in bac...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2008.10.032

    authors： Stoicov C,Saffari R,Houghton J

    更新日期：2009-05-01 00:00:00

  • Steady-state pharmacokinetics and pharmacodynamics of cefepime administered by prolonged infusion in hospitalised patients.

    abstract：:The objective of this study was to evaluate the steady-state pharmacokinetics and pharmacodynamics of cefepime administered by prolonged infusion in hospitalised patients requiring antimicrobial therapy. Nine patients received 1g every 8h (q8h), infused over 4h, and steady-state pharmacokinetic parameters were determi...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2010.08.016

    authors： Cheatham SC,Shea KM,Healy DP,Humphrey ML,Fleming MR,Wack MF,Smith DW,Sowinski KM,Kays MB

    更新日期：2011-01-01 00:00:00

  • Antibacterial activity of moxifloxacin against periodontal anaerobic pathogens involved in systemic infections.

    abstract：:The in vitro activity of moxifloxacin was compared with that of penicillin G, amoxycillin/clavulanate, cefoxitin, erythromycin, clindamycin and metronidazole against 158 isolates associated with periodontal infections. MIC(50)/MIC(90) values of moxifloxacin were respectively 0.06/0.5 mg/l for Porphyromonas gingivalis ...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/s0924-8579(02)00190-5

    authors： Milazzo I,Blandino G,Musumeci R,Nicoletti G,Lo Bue AM,Speciale A

    更新日期：2002-12-01 00:00:00

  • In vitro activity of piperacillin/tazobactam against isolates from patients enrolled in clinical trials.

    abstract：:The in vitro activity of piperacillin alone or titrated with a constant concentration of 4 mug/ml tazobactam was evaluated against 3962 baseline pathogens isolated from 1899 patients enrolled in 9 clinical trial studies in North America. Tazobactam increased susceptibility rates of piperacillin for Enterobacteriaceae ...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/0924-8579(96)00004-0

    authors： Kuck NA,Jacobus NV,Spengler MD,Testa RT

    更新日期：1996-05-01 00:00:00

  • Continuous versus intermittent infusion of cefepime in neurosurgical patients with post-operative intracranial infections.

    abstract：:Cefepime is administered as an intermittent infusion (II); however, continuous infusion (CI) may be advantageous because β-lactam antibiotics exhibit time-dependent antibacterial activity. This retrospective, non-randomised, comparative study included 68 neurosurgical patients with post-operative intracranial infectio...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2013.08.019

    authors： Huang H,Huang S,Zhu P,Xi X

    更新日期：2014-01-01 00:00:00

  • Linezolid pharmacodynamics with Staphylococcus aureus in an in vitro dynamic model.

    abstract：:To describe the relationship between the ratio of the 24-h area under the concentration-time curve (AUC(24)) to minimum inhibitory concentration (MIC) as well as the effect of linezolid on Staphylococcus aureus, the killing kinetics of three S. aureus strains was studied by in vitro simulation of 5-day antibiotic dosi...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2008.09.006

    authors： Strukova EN,Smirnova MV,Vostrov SN,Lubenko IY,Firsov AA,Zinner SH,Portnoy YA

    更新日期：2009-03-01 00:00:00

  • Bactericidal effect of sulbactam against Acinetobacter baumannii ATCC 19606 studied by 2D-DIGE and mass spectrometry.

    abstract：:Acinetobacter baumannii has been associated with several severe hospital-acquired infections such as ventilator-associated pneumonia and meningitis. Sulbactam, a β-lactamase inhibitor, is usually combined with β-lactam antibiotics to treat infections. It has been found that sulbactam alone may be used to treat infecti...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2014.03.004

    authors： Lin CH,Su SC,Ho KH,Hsu YW,Lee KR

    更新日期：2014-07-01 00:00:00

  • Pharmacokinetics of piperacillin-tazobactam in plasma, peritoneal fluid and peritoneum of surgery patients, and dosing considerations based on site-specific pharmacodynamic target attainment.

    abstract：:Piperacillin-tazobactam (PIP-TAZ) is commonly used to treat intraabdominal infections; however, its penetration into abdominal sites is unclear. A pharmacokinetic analysis of plasma, peritoneal fluid, and peritoneum drug concentrations was conducted to simulate dosing regimens needed to attain the pharmacodynamic targ...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2017.03.025

    authors： Murao N,Ohge H,Ikawa K,Watadani Y,Uegami S,Shigemoto N,Shimada N,Yano R,Kajihara T,Uemura K,Murakami Y,Morikawa N,Sueda T

    更新日期：2017-09-01 00:00:00

  • Emergence of extended-spectrum β-lactam resistance among Escherichia coli at a US academic children's hospital is clonal at the sequence type level for CTX-M-15, but not for CMY-2.

    abstract：:Resistance to extended-spectrum β-lactams is increasing worldwide among Escherichia coli and has been linked to a small number of emergent clones (e.g. ST38, ST131 and ST405) recovered from extraintestinal infections in community and hospital settings. There are, however, limited data about the relative contributions ...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2013.01.006

    authors： Weissman SJ,Adler A,Qin X,Zerr DM

    更新日期：2013-05-01 00:00:00

  • Teicoplanin for treating enterococcal infective endocarditis: A retrospective observational study from a referral centre in Spain.

    abstract：:This study aimed to evaluate the effectiveness and safety of teicoplanin for treating enterococcal infective endocarditis (EIE). A retrospective analysis of a prospective cohort of definite EIE patients treated with teicoplanin in a Spanish referral centre (2000-2017) was performed. The primary outcome was mortality d...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2018.10.003

    authors： Escolà-Vergé L,Fernández-Hidalgo N,Rodríguez-Pardo D,Pigrau C,González-López JJ,Bartolomé R,Almirante B

    更新日期：2019-02-01 00:00:00

  • Characterisation of a multidrug-resistant Bacteroides fragilis isolate recovered from blood of a patient in Denmark using whole-genome sequencing.

    abstract：:Here we describe a patient undergoing extensive abdominal surgery and hyperthermic intraperitoneal chemotherapy due to primary adenocarcinoma in the sigmoid colon with peritoneal carcinomatosis. During hospitalisation the patient suffered from bacteraemia with a multidrug-resistant Bacteroides fragilis isolate. Whole-...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2015.02.024

    authors： Ank N,Sydenham TV,Iversen LH,Justesen US,Wang M

    更新日期：2015-07-01 00:00:00

  • Predictive value of nalidixic acid resistance for detecting salmonellae with decreased ciprofloxacin susceptibility.

    abstract：:Seventy-three Salmonella isolates classified as ciprofloxacin susceptible when using the criteria of the National Committee for Clinical Laboratory Standards were studied for nalidixic acid (NA) resistance. The aim of the study was to determine the predictive value of nalidixic acid resistance in screening for decreas...

    journal_title：International journal of antimicrobial agents

    pub_type： 杂志文章

    doi：10.1016/j.ijantimicag.2003.09.014

    authors： Albayrak F,Cokca F,Erdem B,Aysev AD

    更新日期：2004-04-01 00:00:00