Abstract:
:The rate of diffusion of serum albumin (MW 6.9 x 10(4) D) out of beads of calcium alginate gels depends upon the concentration and uronic acid composition of the alginate (ManA/GulA ratio), the conditions under which the beads are produced, the pH, and the temperature. The diffusion coefficient decreases with increasing alginate concentration, and (ManA/GulA) ratio and with decreasing pH. Diffusion out of the beads, in which the alginate is uniformly distributed (homogeneous gel), is faster than out of the beads in which the alginate is concentrated at the surface (inhomogeneous gel). The temperature dependence of the diffusion coefficient follows the Arrhenius law, with an activation energy of approximately 23 kJ x mol(-1).
journal_name
Biotechnol Bioengjournal_title
Biotechnology and bioengineeringauthors
Martinsen A,Storrø I,Skjårk-Braek Gdoi
10.1002/bit.260390210subject
Has Abstractpub_date
1992-01-20 00:00:00pages
186-94issue
2eissn
0006-3592issn
1097-0290journal_volume
39pub_type
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