Peripheral nerve function in sepsis and multiple organ failure.

Abstract:

:Forty-three patients who had sepsis and multiple organ failure (critical illness) were studied prospectively to determine the incidence and severity of peripheral nerve function and to correlate such function with a number of variables. Electrophysiologic studies indicated a primary axonal degeneration of motor and sensory fibers in 30 (70 percent). Fifteen (30 percent) had the clinical signs of difficulty in weaning from assisted ventilation, weakness of limb muscles, and reduced or absent deep tendon reflexes. Full recovery from the polyneuropathy occurred among the 23 (53 percent) who survived, except three who had a very severe polyneuropathy. A peripheral nerve function index, computed from electrophysiologic measurements, showed statistically significant (p less than 0.01) negative correlations with the time in the critical care unit, and the serum glucose value; the serum albumin level showed a positive correlation. Multiple regression analyses indicated all three factors accounted for 47 percent (r2 = 0.4678) of all potential variables. In a separate analysis, the nerve function index correlated with the amplitude of the diaphragm compound muscle action potential (p less than 0.01). The results were consistent with the polyneuropathy being due to the same mechanisms that are currently postulated to cause dysfunction in this syndrome of other organ systems (including the neuromuscular respiratory system).

journal_name

Chest

journal_title

Chest

authors

Witt NJ,Zochodne DW,Bolton CF,Grand'Maison F,Wells G,Young GB,Sibbald WJ

doi

10.1378/chest.99.1.176

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

176-84

issue

1

eissn

0012-3692

issn

1931-3543

pii

S0012-3692(16)30267-7

journal_volume

99

pub_type

杂志文章

相关文献

CHEST文献大全
  • Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients.

    abstract:BACKGROUND:Airway inflammation is important in the development and progression of asthma. Activation of inflammatory cells induces a respiratory burst resulting in the production of reactive oxygen species, such as H(2)O(2). The aim of this study was to measure the concentration of H(2)O(2) in exhaled breath condensate...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.120.4.1136

    authors: Emelyanov A,Fedoseev G,Abulimity A,Rudinski K,Fedoulov A,Karabanov A,Barnes PJ

    更新日期:2001-10-01 00:00:00

  • Erythrocytic glutathione in cystic fibrosis. A possible marker of pulmonary dysfunction.

    abstract::To evaluate the role of red blood cell (RBC) antioxidants as clinical markers of oxidative exposure, we measured RBC glutathione (GSH) concentrations in 32 adult patients with cystic fibrosis (CF), and 8 healthy age-matched control subjects. We chose patients with CF because this disease is characterized by severe bro...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.105.5.1470

    authors: Mangione S,Patel DD,Levin BR,Fiel SB

    更新日期:1994-05-01 00:00:00

  • T wave inversion associated with severe theophylline toxicity.

    abstract::Adverse cardiovascular effects are commonly seen in severe theophylline poisoning. Primary ST-T wave changes have not been described previously. We report T wave inversion associated with severe theophylline toxicity in a 33-year-old woman with no evidence of organic heart disease. The T wave inversion resolved after ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.96.2.429

    authors: Kolander SA,Nydegger CC,Porter RS

    更新日期:1989-08-01 00:00:00

  • Natriuretic peptides, respiratory disease, and the right heart.

    abstract::It is well-recognized that atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are raised in conditions with ventricular volume and pressure overload. In addition to this established role in left ventricular congestive cardiac failure, there is good evidence that BNP has a diagnostic role in right ve...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.126.4.1330

    authors: Yap LB,Mukerjee D,Timms PM,Ashrafian H,Coghlan JG

    更新日期:2004-10-01 00:00:00

  • Successful withdrawal of long-term epoprostenol therapy for pulmonary arterial hypertension.

    abstract:BACKGROUND:IV epoprostenol treatment of pulmonary arterial hypertension (PAH) has been believed to require an indefinite duration of therapy OBJECTIVE:To describe the successful discontinuation of long-term epoprostenol therapy in four patients DESIGN:Case reports SETTING:Outpatient clinic, tertiary-care hospital P...

    journal_title:Chest

    pub_type: 杂志文章

    doi:

    authors: Kim NH,Channick RN,Rubin LJ

    更新日期:2003-10-01 00:00:00

  • An analysis of in vitro T cell responsiveness in nontuberculous mycobacterial infection.

    abstract::In vitro cell-mediated immunity was examined in patients infected with nontuberculous mycobacteria, Mycobacterium avium-intracellulare complex in Japan. Peripheral blood lymphocytes of patients, as compared with those of tuberculous patients or tuberculin-positive healthy donors, showed depressed in vitro blastogenic ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.94.4.822

    authors: Tsuyuguchi I,Shiratsuchi H,Okuda Y,Yamamoto Y

    更新日期:1988-10-01 00:00:00

  • An optimal dose of perfluorocarbon for respiratory mechanics in partial liquid ventilation for dependent lung-dominant acute lung injury.

    abstract:BACKGROUND:Despite increasing knowledge about partial liquid ventilation (PLV), the optimal dose of perfluorocarbon (PFC) is not yet established. Because there exist normal regions in the lung with ARDS and because PLV in the normal lung results in worsened gas exchange, we postulated that the optimal dose of PFC for P...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.117.1.199

    authors: Lim CM,Koh Y,Jung BO,Lee SD,Kim WS,Kim DS,Kim WD

    更新日期:2000-01-01 00:00:00

  • Current status of the implantable cardioverter-defibrillator.

    abstract::Clinical trials have established the superiority of the implantable cardioverter-defibrillator (ICD) over antiarrhythmic drug therapy in survivors of sudden cardiac death and in high-risk patients with coronary artery disease. The ICD has evolved to overcome the limitation of earlier devices that required thoracotomy ...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.119.4.1210

    authors: Gollob MH,Seger JJ

    更新日期:2001-04-01 00:00:00

  • Brief questionnaires for patient-reported outcomes in asthma: validation and usefulness in a primary care setting.

    abstract:UNLABELLED:STUDY OBJECTIVES AND DESIGN: Health-related quality of life (QoL) instruments are generally used for studies of asthma in specialized settings. For primary care use, there is a need for brief and simple questionnaires for structured patient-reported outcomes. We validated the Mini-Asthma Quality of Life Ques...

    journal_title:Chest

    pub_type: 杂志文章,多中心研究

    doi:10.1378/chest.129.4.925

    authors: Ehrs PO,Nokela M,Ställberg B,Hjemdahl P,Wikström Jonsson E

    更新日期:2006-04-01 00:00:00

  • Pott's disease. A resurgent challenge to the thoracic surgeon.

    abstract::Nineteen patients were treated at the Los Angeles County Harbor/UCLA Medical Center between 1971 and 1986 for tuberculosis of the spine. Fourteen were immigrants, a high-risk group. A high index of suspicion is required for Pott's disease, which occurs in fewer than 1 percent of patients with tuberculosis, often prese...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.95.1.145

    authors: Omari B,Robertson JM,Nelson RJ,Chiu LC

    更新日期:1989-01-01 00:00:00

  • Value of F-18 fluorodeoxyglucose positron emission tomography for predicting the clinical outcome of patients with aggressive lymphoma prior to and after autologous stem-cell transplantation.

    abstract:STUDY OBJECTIVES:To determine and compare the values of positron emission tomography (PET) with F-18 fluorodeoxyglucose (FDG) and CT for predicting clinical outcome of patients with aggressive lymphoma undergoing salvage cytoreductive chemotherapy followed by high-dose chemotherapy and autologous stem-cell transplantat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.124.2.608

    authors: Filmont JE,Czernin J,Yap C,Silverman DH,Quon A,Phelps ME,Emmanouilides C

    更新日期:2003-08-01 00:00:00

  • Hypoplastic left heart syndrome associated with congenital right-sided diaphragmatic hernia and omphalocele.

    abstract::Congenital diaphragmatic hernia (CDH) is associated with a variety of cardiac anomalies. However, its association with hypoplastic left heart syndrome (HLHS) is rare. We treated a female newborn with CDH, HLHS, and omphalocele. The operation for omphalocele and the diaphragmatic defect was successful, although the pat...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.1.263

    authors: Nishimura M,Taniguchi A,Imanaka H,Taenaka N

    更新日期:1992-01-01 00:00:00

  • Left ventricular laceration due to stented prosthesis.

    abstract::Complications following open chest massage in patients with porcine xenografts in the mitral location have not been previously described. The authors report a case of cardiac resuscitation following mitral valve replacement with a stented porcine valve. The patient died following brief closed chest, and then, prolonge...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.77.2.216

    authors: Wild LM,Lajos TZ,Lee AB Jr,Wright J

    更新日期:1980-02-01 00:00:00

  • Prolonged mechanical ventilation: review of care settings and an update on professional reimbursement.

    abstract::The goal of this article is to provide an update on recent changes to current procedural terminology codes used for billing physician services for mechanical ventilation in chronic care facilities. In addition to billing information, background data relevant to prolonged mechanical ventilation are reviewed. Topics cov...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.07-0656

    authors: White AC,O'Connor HH,Kirby K

    更新日期:2008-02-01 00:00:00

  • Talc pleurodesis through indwelling pleural catheters for malignant pleural effusions: retrospective case series of a novel clinical pathway.

    abstract::Malignant pleural effusions cause significant morbidity, but there is no gold standard minimally invasive treatment. A new therapeutic approach combines talc pleurodesis and indwelling pleural catheters (IPCs) to enable outpatient management. This case series summarizes the safety and efficacy data of all patients (24...

    journal_title:Chest

    pub_type: 临床试验,杂志文章

    doi:10.1378/chest.14-0394

    authors: Ahmed L,Ip H,Rao D,Patel N,Noorzad F

    更新日期:2014-12-01 00:00:00

  • Felodipine improves pulmonary hemodynamics in chronic obstructive pulmonary disease.

    abstract::Pulmonary hypertension in chronic obstructive pulmonary disease (COPD) is associated with a poor prognosis. Reduction of pulmonary artery pressure in COPD by prolonged oxygen treatment has been shown to be associated with increased survival. In an attempt to find a suitable pharmacologic method of reducing pulmonary a...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.5.1354

    authors: Sajkov D,McEvoy RD,Cowie RJ,Bradley JA,Antic R,Morris RG,Frith PA

    更新日期:1993-05-01 00:00:00

  • The basics of medical malpractice: a primer on navigating the system.

    abstract::Medical malpractice with its associated costs, including insurance premiums, impact on practice, consequences for career and insurability, and emotional toll, is a reality of practicing medicine in the United States. Understanding the types of claims that may be asserted, the issues to consider when securing insurance...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.08-0186

    authors: Nepps ME

    更新日期:2008-11-01 00:00:00

  • Noninvasive pressure support ventilation in patients with acute respiratory failure.

    abstract::To further delineate indications for noninvasive pressure support ventilation (NIPSV), we proposed this noninvasive technique as an alternative to endotracheal intubation in 17 consecutive patients with acute respiratory failure from various causes. Eight patients (47 percent) were successfully ventilated with NIPSV, ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.103.3.907

    authors: Wysocki M,Tric L,Wolff MA,Gertner J,Millet H,Herman B

    更新日期:1993-03-01 00:00:00

  • The Vital Capacity Is Vital: Epidemiology and Clinical Significance of the Restrictive Spirometry Pattern.

    abstract::Epidemiologic research has revealed a substantial portion of the general population with abnormal spirometry results that are characterized by decreased FEV1 and FVC but a preserved FEV1/FVC ratio. This restrictive spirometry pattern (RSP) is inconsistently defined in the literature and not well addressed by current g...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.15-1045

    authors: Godfrey MS,Jankowich MD

    更新日期:2016-01-01 00:00:00

  • Emergency Medical Treatment and Labor Act: what every physician should know about the federal antidumping law.

    abstract::Since 1986, the Emergency Medical Treatment and Labor Act (EMTALA) has imposed an obligation on hospitals and physicians to evaluate and stabilize patients who present to a hospital ED seeking care. Available sanctions for noncompliance include fines, damages awarded in civil litigation, and exclusion from Medicare. E...

    journal_title:Chest

    pub_type: 杂志文章,评审

    doi:10.1378/chest.14-2046

    authors: Hyman DA,Studdert DM

    更新日期:2015-06-01 00:00:00

  • Detection of viable myocardium by transvenous myocardial contrast echocardiography using harmonic power Doppler: canine model of acute coronary occlusion and reperfusion.

    abstract:STUDY OBJECTIVE:To assess whether myocardial contrast echocardiography (MCE) using harmonic power Doppler (HPD) in conjunction with the transvenous contrast agent SHU 563A would be useful in detecting stunned but viable myocardium. DESIGN:Acute coronary occlusion (2 to 3 h) followed by 1 h of reperfusion was created i...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.120.2.567

    authors: Teupe C,Takeuchi M,Yao J,Avelar E,Pandian N

    更新日期:2001-08-01 00:00:00

  • The effects of helium-hyperoxia on 6-min walking distance in COPD: a randomized, controlled trial.

    abstract:BACKGROUND:We hypothesized that breathing helium-hyperoxia (HeO2) would significantly improve 6-min walking test (6MWT) distance in COPD subjects. METHODS:This was a blinded, randomized crossover study. At visit 1, we assessed pulmonary function, exercise capacity, and 6MWT distance. Visits 2 and 3 consisted of four 6...

    journal_title:Chest

    pub_type: 杂志文章,随机对照试验

    doi:10.1378/chest.06-2514

    authors: Marciniuk DD,Butcher SJ,Reid JK,MacDonald GF,Eves ND,Clemens R,Jones RL

    更新日期:2007-06-01 00:00:00

  • Malfunctioning electrocardiographic monitor simulating sinus arrest.

    abstract::A 64-year-old patient was admitted to the hospital with a history of two syncopal episodes. The results of the physical examination, resting electrocardiogram and His-bundle study were all normal. Study with a 24-hour ECG monitor (Holter) was at first interpreted as demonstrating periods of sinus arrest. However, more...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.68.4.582

    authors: Kronzon I,Schloss M,Bear G

    更新日期:1975-10-01 00:00:00

  • Controlled trial of a continuous irrigation suction catheter vs conventional intermittent suction catheter in clearing bronchial secretions from ventilated patients.

    abstract::Continuous irrigation-suction catheter (Irri-cath) is a double-lumen device that allows for simultaneous saline solution infusion and aspiration. This system may theoretically be more effective than conventional dry intermittent suction due to its vortex principle. To test this hypothesis, we performed 200 suction man...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.103.4.1227

    authors: Isea JO,Poyant D,O'Donnell C,Faling LJ,Karlinsky J,Celli BR

    更新日期:1993-04-01 00:00:00

  • Combined dose ratios of dopamine and dobutamine and right ventricular performance after cardiac surgery.

    abstract::The effect of combined administration of different dose ratios of dobutamine (DB) and dopamine (DA) (DB/DA ratio of 1:1; 1.5:0.5; 2:0; 0.5:1.5; and 0:2), with the added dose kept constant (10 micrograms/kg/min-20 micrograms/kg/min), on right ventricular function (measured by the thermal washout method with the aid of ...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.101.5.1197

    authors: Imai T,Saitoh K,Kani H,Fujita T,Murata K

    更新日期:1992-05-01 00:00:00

  • Variable severity of pulmonary disease in adults with identical cystic fibrosis mutations.

    abstract::Adults with CF followed in a university center were assessed for the presence of the most common CF gene mutation, delta-F508. Excluding one member of a sibling pair, 29 of 55 subjects had two copies of delta-F508 (homozygotes), 23 had one copy of delta-F508 with the other CF mutation not identified (complex heterozyg...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.102.2.506

    authors: Burke W,Aitken ML,Chen SH,Scott CR

    更新日期:1992-08-01 00:00:00

  • Peak expiratory flow with or without a brief postinspiratory pause.

    abstract:BACKGROUND:The duration of postinspiratory pause prior to forced expiration may significantly influence the peak expiratory flow (PEF) measured during maximal forceful expirations. In comparison with maneuvers without a postinspiratory pause, maneuvers with 4 to 6-s pause at total lung capacity (TLC) result in decrease...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.128.1.442

    authors: Omar T,Alawadhi H,Soubani AO,Tzelepis GE

    更新日期:2005-07-01 00:00:00

  • Effect of inhaled norepinephrine on the nitroglycerin-induced bronchodilatation in asthmatics.

    abstract::Previous studies on the bronchodilating effect of nitrates yielded conflicting results. We hypothesized that the concomitant bronchial vasodilatation induced by nitrates may limit the increase of airway patency due to bronchial smooth muscle relaxation. To test this hypothesis, we evaluated the bronchodilating effect ...

    journal_title:Chest

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1378/chest.107.1.169

    authors: Rolla G,Bucca C,Brussino L

    更新日期:1995-01-01 00:00:00

  • Congenital atrioventricular block in right atrial isomerism (asplenia). A case due to atrionodal discontinuity.

    abstract::The association of complex congenital heart disease with asplenia syndrome and congenital AV block is described in a newborn. Cardiovascular lesions were right atrial isomerism, d-loop, discordant ventriculoarterial connection, pulmonary stenosis, total anomalous pulmonary venous drainage, absent right pulmonary arter...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.85.4.578

    authors: Rossi L,Montella S,Frescura C,Thiene G

    更新日期:1984-04-01 00:00:00

  • Snoring, nocturnal hypoxemia, and the effect of oxygen inhalation.

    abstract::Men who snore heavily have an increased incidence of hypertension, angina, stroke, and neuropsychologic dysfunction, which may be due to nocturnal oxygen desaturation. Nocturnal oxygen therapy might be beneficial to such individuals by improving oxygenation and relieving tissue hypoxia. Twenty-eight asymptomatic heavy...

    journal_title:Chest

    pub_type: 杂志文章

    doi:10.1378/chest.92.3.411

    authors: Block AJ,Hellard DW,Cicale MJ

    更新日期:1987-09-01 00:00:00