Erythrocytic glutathione in cystic fibrosis. A possible marker of pulmonary dysfunction.

abstract：BACKGROUND:We recently showed that administration of the combination of the noradrenergic drug atomoxetine plus the antimuscarinic oxybutynin (ato-oxy) prior to sleep greatly reduced OSA severity, likely by increasing upper airway dilator muscle activity during sleep. In patients with OSA who performed the ato-oxy tria...

journal_title：Chest

authors： Taranto-Montemurro L,Messineo L,Azarbarzin A,Vena D,Hess LB,Calianese NA,White DP,Wellman A,Sands SA

更新日期：2020-06-01 00:00:00

abstract：STUDY OBJECTIVES:Community-acquired pneumonia (CAP) is a widespread disease with important implications for health-care systems worldwide. This study investigated direct costs, treatment patterns, and outcomes associated with two patient cohorts hospitalized with CAP. DESIGN:The study design was naturalistic, prospect...

journal_title：Chest

authors： Bauer TT,Welte T,Ernen C,Schlosser BM,Thate-Waschke I,de Zeeuw J,Schultze-Werninghaus G

更新日期：2005-10-01 00:00:00

abstract：:Six patients with hemoptysis were treated by endobronchial sealing, with n-butyl cyanoacrylate, of the bleeding segment or subsegment. There was an immediate arrest of bleeding without any recurrence for a mean follow-up period of 127 (+/- 67.17) days. Endobronchial sealing appears to be an effective method of managin...

journal_title：Chest

authors： Bhattacharyya P,Dutta A,Samanta AN,Chowdhury SR

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:COPD has traditionally been defined by the presence of irreversible airflow limitation on spirometry using either the GOLD (Global Initiative for Chronic Obstructive Lung Disease) or American Thoracic Society/European Respiratory Society criteria (lower limit of normal [LLN]). We have observed that some pati...

journal_title：Chest

authors： Lutchmedial SM,Creed WG,Moore AJ,Walsh RR,Gentchos GE,Kaminsky DA

更新日期：2015-07-01 00:00:00

abstract：:Right-sided chest lead ECGs (V3R to V6R) were recorded in 110 normal male subjects who were between the ages of 17 and 22 years old (mean, 17.9 years). The prevalence of the rS pattern decreased from V3R (89 percent) to V6R (37 percent). However, the opposite was the case for the rSr pattern (10 percent in V3R and 36 ...

journal_title：Chest

authors： Tan CC,Hiew TM,Chia BL

更新日期：1990-03-01 00:00:00

abstract：:In November 2007, the Josiah Macy, Jr. Foundation convened a conference to address a number of complex issues concerning continuing education (CE) in the health professions. Participants concluded that CE, as currently practiced, does not focus adequately on improving clinician performance and patient care, is too dep...

journal_title：Chest

authors： Leach DC,Fletcher SW

更新日期：2008-12-01 00:00:00

abstract：:The purpose of this phase 1 study was to determine the toxicity and effectiveness of recombinant interleukin-2 (RU 49637 Roussel Uclaf-France) administered by continuous pleural infusion for 5 days to patients with different histologic subtypes of pleural cancer. Incremental doses of rIL-2 from 3 x 10(6) to 24 x 10(6)...

journal_title：Chest

authors： Astoul P,Viallat JR,Laurent JC,Brandely M,Boutin C

更新日期：1993-01-01 00:00:00

abstract：:A 64-year-old patient was admitted to the hospital with a history of two syncopal episodes. The results of the physical examination, resting electrocardiogram and His-bundle study were all normal. Study with a 24-hour ECG monitor (Holter) was at first interpreted as demonstrating periods of sinus arrest. However, more...

journal_title：Chest

authors： Kronzon I,Schloss M,Bear G

更新日期：1975-10-01 00:00:00

abstract：:The chest radiograph of a woman with acute asthma showed signs of obstructive emphysema of the left lung. Fiberoptic bronchoscopy excluded obstruction of a large bronchus. The signs disappeared after antiasthmatic treatment, suggesting that they were caused by airway closure. In usual asthma, airway closure affects bo...

journal_title：Chest

authors： DiFrancia M,Barbier D,Orehek J

更新日期：1993-12-01 00:00:00

abstract：:Lymphoid interstitial pneumonia (LIP) is regarded as both a disease and a nonneoplastic, inflammatory pulmonary reaction to various external stimuli or systemic diseases. It is an uncommon condition with incidence and prevalence rates that are largely unknown. Liebow and Carrington originally classified LIP as an idio...

journal_title：Chest

authors： Swigris JJ,Berry GJ,Raffin TA,Kuschner WG

更新日期：2002-12-01 00:00:00

abstract：STUDY OBJECTIVES:The purpose of this study was to investigate the test-retest reliability, repeatability, and sensitivity of the modified shuttle test (MST) in adult patients with cystic fibrosis (CF). DESIGN:: Prospective study. SETTING:Adult CF Unit, Belfast City Hospital. PATIENTS:: Adult patients with CF. INTER...

journal_title：Chest

authors： Bradley J,Howard J,Wallace E,Elborn S

更新日期：2000-06-01 00:00:00

abstract：STUDY OBJECTIVES:The etiologic role of bacterial pathogens isolated from sputum culture in 40 to 50% of acute exacerbations of chronic bronchitis (AECB) is controversial. If bacterial pathogens cause these AECB, they should be associated with greater neutrophilic airway inflammation than pathogen-negative exacerbations...

journal_title：Chest

authors： Sethi S,Muscarella K,Evans N,Klingman KL,Grant BJ,Murphy TF

更新日期：2000-12-01 00:00:00

abstract：:The criteria of the American Thoracic Society (ATS) for determining the end-point of the forced vital capacity (FVC) maneuver were compared with an algorithm employed by a computer system (Hewlett-Packard), which yields a later end-point. The 150 subjects tested were divided into five groups of 30 on the basis of the ...

journal_title：Chest

authors： Pistelli G,Carmignani G,Paoletti P,Di Pede F,Viegi G,Carrozzi L,Celi A,Giuntini C

更新日期：1987-01-01 00:00:00

abstract：:A series of 15 patients with life threatening, massive hemoptysis is reported. Thirteen of these patients underwent immediate operative treatment with only three deaths. One died after bronchoscopic identification of the bleeding site while awaiting elective thoracotomy. The other patient left the hospital against med...

journal_title：Chest

authors： McCollun WB,Mattox KL,Guinn GA,Beall AC Jr

更新日期：1975-02-01 00:00:00

abstract：OBJECTIVE:To determine the success rate and correlates of ambulatory peak expiratory flow (PEF) monitoring in an epidemiologic study. DESIGN:An observational survey. SETTING:Several communities in California. PARTICIPANTS:We studied 1,223 nonsmoking men and women (mean age, 66 years) from an established cohort. OUT...

journal_title：Chest

authors： Enright PL,Burchette RJ,Peters JA,Lebowitz MD,McDonnell WF,Abbey DE

更新日期：1997-10-01 00:00:00

abstract：:A pulmonary arteriovenous malformation was embolized in a patient with hereditary hemorrhagic telangiectasia. Several unusual complications, including early deflation of a detachable balloon, migration of a coil, and development of severe pulmonary hypertension, occurred. Pulmonary hypertension was attributed to a coe...

journal_title：Chest

authors： Haitjema T,ten Berg JM,Overtoom TT,Ernst JM,Westermann CJ

更新日期：1996-05-01 00:00:00

abstract：:At the time of bronchoscopic observation, 28 of 31 patients proved to have aspirated gastric contents by the presence of gastric contents in the trachea or by direct observation of gastric aspiration followed by respiratory distress and erythema of subsegmental bronchi. Since gastric aspiration is a difficult diagnosi...

journal_title：Chest

authors： Wolfe JE,Bone RC,Ruth WE

更新日期：1976-10-01 00:00:00

abstract：:This is the first reported case of discrete fibrous subaortic stenosis in tetralogy of Fallot. Transaortic excision of the subaortic membrane was readily accomplished. To detect this and other forms of left ventricular outflow-tract obstruction in tetralogy of Fallot before surgery, routine selective left ventriculogr...

journal_title：Chest

authors： Sanders JH,Van Praagh R,Sade RM

更新日期：1976-04-01 00:00:00

abstract：:Nd-YAG laser resection of a completely obstructing right mainstem tumor in a 36-year-old man was complicated by right lung hyperinflation and left lung collapse and accompanying ventilatory failure. This was attributed to obstruction of the right mainstem bronchus during exhalation, but not inhalation, in a patent but...

journal_title：Chest

authors： Fairfax WR,Rollins RJ

更新日期：1988-06-01 00:00:00

abstract：:In recent months, medical institutions across the United States redoubled their efforts to examine the history of race and racism in medicine, in classrooms, in research, and in clinical practice. In this essay, I explore the history of racialization of the spirometer, a widely used instrument in pulmonary medicine to...

journal_title：Chest

authors： Braun L

更新日期：2020-10-24 00:00:00

abstract：:The aim of this study was to investigate whether the demonstration of plasma cells (PC), which are normally absent in bronchoalveolar lavage (BAL) fluid, facilitates differentiation among pulmonary disorders. Initial BAL fluid samples of 1,260 patients were analyzed. In 83 of these, PC were found. Of these 83, 47 were...

journal_title：Chest

authors： Drent M,van Velzen-Blad H,Diamant M,Wagenaar SS,Donckerwolck-Bogaert M,van den Bosch JM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Malignant pleural effusion (MPE) is common. Existing literature on pleural fluid compositions is restricted to cross-sectional sampling with little information on longitudinal changes of fluid biochemistry and cytokines with disease progression. Indwelling pleural catheters provide the unique opportunity for...

journal_title：Chest

authors： Thomas R,Cheah HM,Creaney J,Turlach BA,Lee YC

更新日期：2016-06-01 00:00:00

abstract：:The serum concentration of angiotensin-converting enzyme is frequently elevated in individuals with active sarcoidosis. The enzyme is presumably actively synthesized by the epithelioid and giant cells of the granuloma. Hypersensitivity pneumonitis, resulting from the inhalation of antigens from pigeons by susceptible ...

journal_title：Chest

authors： McCormick JR,Thrall RS,Ward PA,Moore VL,Fink JN

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:The efficacy of a new pharmacologic agent for asthma, in this instance the leukotriene receptor antagonist montelukast, is determined in controlled trials in research subjects. The utility of a new drug is determined by multiple uncontrollable factors in individual patients. OBJECTIVE:To assess the utility ...

journal_title：Chest

authors： Mathison DA,Koziol JA

更新日期：2002-02-01 00:00:00

abstract：STUDY OBJECTIVES:It has been suggested that sleep-disordered breathing (SDB) is a risk factor for ischemic heart disease, and may be associated with increased morbidity and mortality due to cardiovascular disease. The aim of this study was to examine the relation between nocturnal oxygen desaturation (NOD) due to SDB a...

journal_title：Chest

authors： Hayashi M,Fujimoto K,Urushibata K,Uchikawa S,Imamura H,Kubo K

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:To assess whether the presence and duration of air leaks after lobectomy are associated with an increased incidence of cardiopulmonary complications. METHODS:Propensity score analysis was used on 726 patients undergoing pulmonary lobectomy from 1995 through 2004 to form three well-matched pairs of patients: pa...

journal_title：Chest

authors： Brunelli A,Xiume F,Al Refai M,Salati M,Marasco R,Sabbatini A

更新日期：2006-10-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), a major cause of ICU infection, results in high morbidity, mortality, and health-care costs. Multiple risk factors for VAP involve complex host factors and ubiquitous pathogens that require several different types of prevention strategies. Prevention efforts should focus on reduc...

journal_title：Chest

authors： Craven DE

更新日期：2006-07-01 00:00:00

abstract：:Airway pressure release ventilation (APRV), a new ventilatory support technique, was compared with conventional intermittent positive-pressure ventilation plus PEEP (CPPV) in 18 patients with severe acute respiratory failure. Patients were initially stabilized on CPPV and then switched to APRV. The APRV provided effec...

journal_title：Chest

authors： Cane RD,Peruzzi WT,Shapiro BA

更新日期：1991-08-01 00:00:00

abstract：:Cidofovir, a nucleoside analog antiviral agent, has been used with moderate success in the treatment of juvenile laryngeal papillomatosis (JLP) by direct intralesional injection. We report the first case where IV cidofovir was used successfully to treat a rare but lethal multicystic lung disease complicating JLP. A 35...

journal_title：Chest

authors： Dancey DR,Chamberlain DW,Krajden M,Palefsky J,Alberti PW,Downey GP

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:To evaluate an adjustable mandibular positioning appliance for treatment of snoring and sleep apnea. METHODS:One hundred thirty-four patients with baseline apnea/hypopnea index (AHI) of 37 +/- 28 events/h (mean +/- SD) received the appliance. The efficacy of the appliance was assessed by the following invest...

journal_title：Chest

authors： Pancer J,Al-Faifi S,Al-Faifi M,Hoffstein V

更新日期：1999-12-01 00:00:00