Abstract:
:This review briefly defines the heat shock proteins (hsps), their classification and their functions. The hypothesis that links hsps to the development of autoimmunity is explored, together with the rationale for investigation of the relationship between hsps and systemic lupus erythematosus (SLE). Thus, published work on this subject falls into three main categories: the overexpression of hsps in SLE, the development of autoantibodies to hsps in SLE, and the surface expression of hsps in peripheral blood mononuclear cells in SLE. This work is reviewed in detail. In conclusion, we describe areas for further study and outline ways in which this is being approached.
journal_name
Lupusjournal_title
Lupusauthors
Dhillon V,Latchman D,Isenberg Ddoi
10.1177/096120339100100102subject
Has Abstractpub_date
1991-11-01 00:00:00pages
3-8issue
1eissn
0961-2033issn
1477-0962journal_volume
1pub_type
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