Abstract:
BACKGROUND:This study investigates risk factors and the incidence of type 2 diabetes mellitus (type 2 DM) in both sexes of a northern European population. METHODS:A total of 14,223 randomly selected men and women were studied from 1976 to 1978. Patients with diabetes (self-reported type 2 DM or non-fasting plasma glucose >11.1 mmol/l) were excluded. Some 6154 women and 4733 men were studied and followed up in 1981-1983 or in 1991-1994. The significance of risk factors was examined by multiple logistic regression analysis. RESULTS:Initially, a higher proportion of men than women had high, non-fasting blood glucose and triglycerides. Significantly more men (242, 5.4%) than women (152, 2.5%) developed type 2 DM. The odds ratio (OR) for developing diabetes with a BMI above 30 kg/m(2) compared to a BMI of 20-25 kg/m(2) was 8.1 in women and 6.3 in men; for a non-fasting plasma glucose of 8.4-11.0 mmol/l compared to a plasma glucose of 5.5-6.4, the ORs were 7.8 in women and 4.7 in men. The OR for developing diabetes in persons with a non-fasting triglyceride level above 2.0 mmol/l compared to 1.0-2.0 mmol/l was 1.8 in both sexes; women with non -fasting triglycerides below 1.0 mmol/l had an OR of 0.4. CONCLUSION:In a randomly selected northern European population, significantly more men than women develop type 2 DM.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Almdal T,Scharling H,Jensen JS,Vestergaard Hdoi
10.1016/j.ejim.2007.05.011subject
Has Abstractpub_date
2008-01-01 00:00:00pages
40-5issue
1eissn
0953-6205issn
1879-0828pii
S0953-6205(07)00248-8journal_volume
19pub_type
杂志文章abstract::The introduction of substrate reduction therapy (SRT) using miglustat (Zavesca(R)) gives physicians and patients a choice of treatment options for type 1 Gaucher's disease. Enzyme replacement therapy (ERT) has proven a successful approach to treating the haematologic abnormalities and organomegaly. However, long-term ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2006.07.003
更新日期:2006-11-01 00:00:00
abstract::A 59 year old lady had just completed renal dialysis via a central venous catheter when she developed severe chest pain. She subsequently has severe haematemesis and emergency endoscopy showed a lesion in her esophagus consistent with the tip of her venous catheter, and extensive bleeding from the lesion. A chest X-ra...
journal_title:European journal of internal medicine
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abstract:BACKGROUND:Statins are the treatment of choice for lowering LDL-C levels and reducing cardiovascular events. They have a remarkable safety profile, although some patients do not tolerate them. The aim of the study was to summarize the existing data on non-every day statin administration regimens. METHODS:We searched t...
journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2013.04.009
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abstract::There is growing evidence suggesting a causative relationship between adrenal adenomas and metabolic and cardiovascular deteriorations. Although demonstrated frequently in subjects with subclinical Cushing Syndrome, subjects with non-functioning adrenal adenomas feature a variety of metabolic and cardiovascular conseq...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
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abstract:BACKGROUND:In discharged patients with heart failure (HF), diverse conditions can intervene to worsen outcome. We would investigate whether such factors present on hospital admission can affect long-term mortality in subjects hospitalized for acute HF. METHODS:One hundred twenty-three consecutive patients hospitalized...
journal_title:European journal of internal medicine
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abstract::Diabetes mellitus type 2 (T2DM) has been associated with an increased cardiovascular risk. Improving glycaemia or other traditional cardiovascular risk factors may reduce cardiovascular risk in patients with T2DM. However, single risk intervention in T2DM has not provided convincing evidence in the reduction of cardio...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
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abstract:BACKGROUND:Aspiration pneumonia (AP) is an infectious process causing high rates of mortality. The purpose of this study was: 1, to describe the incidence from 2003 to 2013 of AP hospitalizations; 2, to assess time trends in hospital outcomes variables, and; 3, to identify the factors independently associated with in-h...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.12.022
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
pub_type: 临床试验,杂志文章
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journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2008.07.017
更新日期:2009-05-01 00:00:00
abstract::CHF is a disease of high incidence and prevalence in the elderly. Anemia is associated with an increased mortality in these patients. Erythropoietin secretion is reduced in these patients due to complexed mechanisms. Although some improvement in quality of life has been shown when using ESAs it has not been found any ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2013.12.011
更新日期:2014-02-01 00:00:00
abstract::Numerous epidemiological studies have shown an inverse correlation between moderate consumption of alcoholic drinks and the risk of coronary heart disease. Wine, especially red wine, may be more favorable in this respect than beer or spirits because of its high content of flavonoids. These polyphenols originate from t...
journal_title:European journal of internal medicine
pub_type: 杂志文章
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abstract:BACKGROUND:The site of acquisition of infection may have a major impact on outcome. The health care-related (HCR) environment has recently come under scrutiny. In a group of patients with bacteremic septic arthritis (SA), we compared their characteristics, type of SA, microbiology and prognosis according to the site of...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2015.11.013
更新日期:2016-03-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2014.11.007
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Thalassemia minor (Tm) individuals, are generally considered healthy. However, the prognosis of Tm individuals has not been extensively studied. The aim of this study was to evaluate the prognosis of Tm versus controls without β-thalassemia carrier state. METHODS:A total of 26,006 individuals seeking thalas...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2018.06.009
更新日期:2018-08-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2006.07.021
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To assess security of "blind" percutaneous liver biopsy as an ambulatory procedure. MATERIAL AND METHODS:Defining inclusion criteria, surveillance protocol, data from ultrasonography done 6 h after procedure and complications. RESULTS:We analysed 192 percutaneous liver biopsies done between 2000-2007. There...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2009.02.002
更新日期:2009-09-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2011.02.007
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journal_title:European journal of internal medicine
pub_type: 临床试验,杂志文章
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journal_title:European journal of internal medicine
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更新日期:2013-12-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2011.08.021
更新日期:2011-12-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2010.07.019
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Heart failure (HF) is frequent in elderly patients, but few studies have focused on patients older than 84 years. The aim of this study was to evaluate major comorbidities and 1-year survival in HF patients aged ≥85 years compared with younger age groups. METHODS:Patients included in a prospective national ...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejim.2013.01.005
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Vascular endothelium activation is a key pathogenic step in systemic inflammatory response syndrome (SIRS) that can be triggered by both microbial and sterile proinflammatory stimuli. The relevance of soluble adhesion molecules as clinical biomarkers to discriminate between infectious and non-infectious SIRS...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2012.10.009
更新日期:2013-03-01 00:00:00
abstract:AIM:We investigated the association among long-term proton-pump inhibitors (PPIs) use with serum magnesium (Mg) levels in chronic hemodialysis (HD) patients, as well as possible association among PPI use and increased risk of cardiovascular (CVD) morbidity in HD patients. METHODS:Of 418 HD patients that were screened ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.01.026
更新日期:2016-05-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2013.03.015
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:To describe the clinical characteristics and evolution of a series of adult patients hospitalized for neuro-Behçet disease (NBD). METHODS:Consecutive patients admitted for NBD in a teaching hospital were retrospectively selected. Disability at discharge and during follow-up was graded with the modified Rank...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2010.08.003
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:In bromocriptine-treated hyperprolactinemic patients with impaired glucose tolerance, metformin was found to reduce plasma levels of prolactin. No previous study has investigated its impact on plasma prolactin in patients with drug-induced hyperprolactinemia. METHODS:The study included 20 women with antipsy...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.01.015
更新日期:2016-05-01 00:00:00