Single-fiber electromyography of masseter muscle in myasthenia gravis.

Abstract:

:Jitter after axonal microstimulation in the masseter muscle was studied in 30 consecutive patients (12 women) with myasthenia gravis (MG). Patients' mean age was 42.3 (12-75), median disease duration was 3 months (1-72), and onset was ocular (15 cases), oculobulbar (7), bulbar (6), or generalized (2). There were 23 newly-diagnosed patients. Nine cases developed purely ocular MG and 21 cases developed generalized MG. In the latter group, five subjects had a rapidly progressive course and 16 subjects had stable or well-controlled disease (MGFA grade 2-3). Six patients did not have circulating anti-acetylcholine receptor antibodies. Masseter single-fiber electromyography (SFEMG) was abnormal in 6 of 9 ocular MG patients and in all generalized cases (overall sensitivity 27 of 30 cases or 90%; confidence interval 79.3%-100.0% at P = 0.95). Masseter should be considered for SFEMG in diagnosis of MG, especially in cases with bulbar onset.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Khuraibet AJ,Rousseff RT,Behbehani R,al-Shubaili AF,Khan RA

doi

10.1002/mus.20921

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

522-5

issue

4

eissn

0148-639X

issn

1097-4598

journal_volume

37

pub_type

临床试验,杂志文章
  • Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis.

    abstract:INTRODUCTION:A randomized trial demonstrated benefit from thymectomy in nonthymomatous acetylcholine receptor (AChR)-antibody positive myasthenia gravis (MG). Uncontrolled observational and histologic studies suggest thymectomy may not be efficacious in anti-muscle-specific kinase (MuSK)-MG. METHODS:The therapeutic im...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,多中心研究

    doi:10.1002/mus.26404

    authors: Clifford KM,Hobson-Webb LD,Benatar M,Burns TM,Barnett C,Silvestri NJ,Howard JF Jr,Visser A,Crum BA,Nowak R,Beekman R,Kumar A,Ruzhansky K,Chen IA,Pulley MT,Laboy SM,Fellman MA,Howard DB,Kolb NA,Greene SM,Pasnoor M

    更新日期:2019-04-01 00:00:00

  • Spinal irradiation does not inhibit distal axonal sprouting.

    abstract::In an attempt to determine the relative importance of the nerve cell body and of the axon in initiating and controlling axonal regeneration, nerve cell bodies were irradiated and the ability of the distal axon to sprout was examined. Mice were subjected to either 25 or 50 Gray (Gy) of x-irradiation localized to the lu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110513

    authors: Pamphlett RS

    更新日期:1988-05-01 00:00:00

  • Central fatigue assessed by transcranial magnetic stimulation.

    abstract::Central fatigue is a subjective phenomenon which can be examined using transcranial magnetic stimulation (TMS). To assess central fatigue, we compared TMS and peripheral electrical stimulations in patients with central nervous system (CNS) lesions and controls before and after an exhaustive task. The recovery times of...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-4598(199611)19:11<1429::AID-MUS

    authors: Liepert J,Kotterba S,Tegenthoff M,Malin JP

    更新日期:1996-11-01 00:00:00

  • Temperature dependence of contraction characteristics in developing rat muscles.

    abstract::Contractions of rat extensor digitorum longus (EDL, a fast muscle) and soleus (SOL, a slow muscle) muscles of different ages (1-4 weeks) were recorded in vitro with direct stimulation and at different temperatures (range 35-10 degrees C). Twitch tension in 4-week-old EDL muscle increased in cooling from 35 to 20 degre...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880100902

    authors: Wylie SR,Ranatunga KW

    更新日期:1987-11-01 00:00:00

  • Asymptomatic vasculitic neuropathy.

    abstract:INTRODUCTION:We performed a retrospective analysis of the clinical, pathological, and electrophysiological features of 21 cases of Asymptomatic vasculitic neuropathy (AsVN). METHODS:Among 270 patients with biopsy-proven vasculitic neuropathy, we identified 21 (7.8%) who had asymptomatic neuropathy. RESULTS:Of the 21 ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24494

    authors: Kurt S,Alsharabati M,Lu L,Claussen GC,Oh SJ

    更新日期:2015-07-01 00:00:00

  • Soleus-specific myopathy induced by passive stretching under local tetanus.

    abstract::Twenty-four adult albino rats were injected with tetanus toxin into the right gastrocnemius muscle and then subjected to sustained dorsiflexion of the right ankle joint for 2 to 14 days. Histologic examinations of the soleus after this procedure showed myopathic changes, characterized by variations in fiber diameters,...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880131007

    authors: Mizuno Y,Chou SM

    更新日期:1990-10-01 00:00:00

  • Urinary retention and sympathetic sphincter obstruction in axonal Guillain-Barré syndrome.

    abstract::A 62-year-old woman with axonal Guillain-Barré syndrome developed weakness and urinary retention simultaneously. The retention failed to recover for 10 months even after she regained the ability to walk. The patient exhibited no postural hypotension. Videourodynamics showed that the retention was caused not by the bla...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20639

    authors: Sakakibara R,Uchiyama T,Tamura N,Kuwabara S,Asahina M,Hattori T

    更新日期:2007-01-01 00:00:00

  • Effects of isaxonine on skeletal muscle reinnervation in the rat: an electrophysiologic evaluation.

    abstract::Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880080205

    authors: Pecot-Dechavassine M,Mira JC

    更新日期:1985-02-01 00:00:00

  • Ultrasound imaging of the quadriceps muscle in elderly athletes and untrained men.

    abstract::Ultrasound (US) technique was applied to measure the thickness, cross-sectional area (CSA), and internal structure of the quadriceps muscle in 70- to 80-year-old endurance and power athletes and untrained men. Isometric knee extension strength was higher in the power athletes than in the other groups. The mean values ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880140607

    authors: Sipilä S,Suominen H

    更新日期:1991-06-01 00:00:00

  • Obstetrical lumbosacral plexus injury.

    abstract::Injuries to the lumbosacral plexus during labor and delivery have been reported in the literature for years, but have lacked electrophysiologic testing to substantiate the location of the nerve injury. We report 2 cases with comprehensive electrophysiologic testing which localizes the site of this obstetrical paralysi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880150812

    authors: Feasby TE,Burton SR,Hahn AF

    更新日期:1992-08-01 00:00:00

  • The utility of a point-of-care sural nerve conduction device for detection of diabetic polyneuropathy: A cross-sectional study.

    abstract:INTRODUCTION:Rapid and accessible methods for diagnosing diabetic polyneuropathy (DPN) have been developed, but not validated, in large cohorts of people with diabetes. METHODS:The performance of a point-of-care device (POCD) was studied in 168 patients with type 2 diabetes, estimating the sensitivity, specificity, po...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26361

    authors: Kural MA,Andersen ST,Andersen NT,Andersen H,Charles M,Finnerup NB,Jensen TS,Tankisi H

    更新日期:2019-02-01 00:00:00

  • Acquired neuromyotonia and peripheral neuropathy in a patient with Hodgkin's disease.

    abstract::Acquired neuromyotonia is characterized by hyperexcitability of motor nerves resulting in continuous muscle fiber activity. It occurs most often as a paraneoplastic syndrome in patients with cancers of the immune system. Antibodies against voltage-gated potassium channels (VGKCs) have been detected in some patients. P...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.1078

    authors: Lahrmann H,Albrecht G,Drlicek M,Oberndorfer S,Urbanits S,Wanschitz J,Zifko UA,Grisold W

    更新日期:2001-06-01 00:00:00

  • Bone density and alendronate effects in Duchenne muscular dystrophy patients.

    abstract:INTRODUCTION:Patients with DMD have low bone mineral density (BMD) and are at high risk for fractures. We examined changes in BMD and the effects of alendronate in DMD patients treated at our institution in the last decade. METHODS:Retrospective cohort study of 39 DMD patients. RESULTS:Patients had screening dual ene...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23948

    authors: Houston C,Mathews K,Shibli-Rahhal A

    更新日期:2014-04-01 00:00:00

  • Reliability of hand-held dynamometry in spinal muscular atrophy.

    abstract::We have assessed the reliability of hand-held myometry in 33 patients with spinal muscular atrophy (SMA), testing elbow flexion, handgrip, three-point pinch, knee flexion, knee extension, and foot dorsiflexion, and determining intraclass correlation coefficients (ICC). Interrater reliability was high for upper limbs, ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,多中心研究

    doi:10.1002/mus.10166

    authors: Merlini L,Mazzone ES,Solari A,Morandi L

    更新日期:2002-07-01 00:00:00

  • Informed consent.

    abstract::Physicians have an ethical and legal duty to obtain patients' informed consent before ordering testing and treatment. Informed consent encompasses informed refusal, the correlative right of patients to refuse tests and therapies they do not want. A patient's informed consent requires adequate information, capacity to ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.1046

    authors: Bernat JL

    更新日期:2001-05-01 00:00:00

  • Role of nerve and tension in maturation of posthatching slow-tonic muscle in chicken.

    abstract::The role of motor innervation and muscle tension in the posthatching maturation of the slow-tonic anterior latissimus dorsi (ALD) muscle of the chicken has been investigated. Modification of the muscle tension was obtained either by maintaining ALD in a shortened state or by stretching, after or without denervation. I...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880121112

    authors: Gardahaut MF,Rouaud TP,Renaud D,Khaskiye A,Le Douarin GH

    更新日期:1989-11-01 00:00:00

  • Canomad presenting without ophthalmoplegia and responding to intravenous immunoglobulin.

    abstract::The acronym CANOMAD encompasses chronic ataxic neuropathy combined with ophthalmoplegia, M protein, cold agglutinins, and anti-disialosyl antibodies.Herein we describe 2 patients presenting with progressive ataxic neuropathy who only developed ophthalmoplegia after a significant delay post-presentation, which in 1 cas...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22167

    authors: Kam C,Balaratnam MS,Purves A,Mills KR,Riordan-Eva P,Pollock S,Bodi I,Munro NA,Bennett DL

    更新日期:2011-11-01 00:00:00

  • Association between muscle architecture and quadriceps femoris H-reflex.

    abstract::The purpose of the present study was to establish the relationship between muscle architecture and H-reflex recordings in quadriceps femoris muscle. H-reflexes were elicited in human quadriceps femoris muscle over a broad area of skin to document the shape and amplitude of the H-potentials. This, in combination with r...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880170604

    authors: Garland SJ,Gerilovsky L,Enoka RM

    更新日期:1994-06-01 00:00:00

  • Sparing of the flexor carpi ulnaris in ulnar neuropathy at the elbow.

    abstract::A common misconception attributes sparing of the flexor carpi ulnaris (FCU) in ulnar neuropathy at the elbow (UNE) to its innervating branch arising "at or above the elbow." We examined the relationship of FCU branches to the medial epicondyle (ME) and humeroulnar aponeurotic arcade (HUA) in 30 cadaver elbows. In only...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880121203

    authors: Campbell WW,Pridgeon RM,Riaz G,Astruc J,Leahy M,Crostic EG

    更新日期:1989-12-01 00:00:00

  • Stem cell route to neuromuscular therapies.

    abstract::As applied to skeletal muscle, stem cell therapy is a reincarnation of myoblast transfer therapy that has resulted from recent advances in the cell biology of skeletal muscle. Both strategies envisage the reconstruction of damaged muscle from its precursors, but stem cell therapy employs precursors that are earlier in...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.10243

    authors: Partridge TA

    更新日期:2003-02-01 00:00:00

  • Muscle metabolic alterations assessed by 31-phosphorus magnetic resonance spectroscopy in mild Becker muscular dystrophy.

    abstract::Although the molecular defect causing Becker muscular dystrophy (BMD) has been identified, the biochemical mechanisms that lead to muscle necrosis remain unclear. Exercise-related muscle metabolism in 9 mildly affected BMD patients was assessed by muscle 31-phosphorus magnetic resonance spectroscopy ((31)P MRS) during...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22181

    authors: Tosetti M,Linsalata S,Battini R,Volpi L,Cini C,Presciutti O,Muntoni F,Cioni G,Siciliano G

    更新日期:2011-11-01 00:00:00

  • Characterization of skeletal muscle effects associated with daptomycin in rats.

    abstract::Daptomycin is a lipopeptide antibiotic with strong bactericidal effects against Gram-positive bacteria and minor side effects on skeletal muscles. The type and magnitude of the early effect of daptomycin on skeletal muscles of rats was quantified by histopathology, examination of contractile properties, Evans Blue Dye...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21691

    authors: Kostrominova TY,Hassett CA,Rader EP,Davis C,Larkin LM,Coleman S,Oleson FB,Faulkner JA

    更新日期:2010-09-01 00:00:00

  • Somatosensory evoked potentials following stimulation of digital nerves.

    abstract::Cortical and spinal somatosensory evoked potentials (SEP) were recorded in healthy individuals following stimulation of digits I, III, and V with an intensity below discomfort level. Peak latency of the earliest cortical negativity (N1) was found to be the most consistent and easily measured parameter, whereas a spina...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/mus.10237

    authors: Kwast-Rabben O,Libelius R,Heikkilä H

    更新日期:2002-10-01 00:00:00

  • Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials.

    abstract:INTRODUCTION:Spinal and bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS) are motor neuron diseases. Sensory impairment is sometimes observed, and electrophysiological involvement has been described in the sensory nerves of SBMA patients. We hypothesized that a sensory nerve conduction study (NCS) ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22291

    authors: Hama T,Hirayama M,Hara T,Nakamura T,Atsuta N,Banno H,Suzuki K,Katsuno M,Tanaka F,Sobue G

    更新日期:2012-02-01 00:00:00

  • Clinical, physiological, and histological features in a kindred with the T3271C melas mutation.

    abstract::The majority of patients with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes) have an A-->G mutation at nucleotide 3243 in mitochondrial transfer (t)RNA. To date there have only been 10 reported cases of MELAS syndrome in patients with a T-->C mutation at position 3271...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199801)21:1<25::aid-mus4>3

    authors: Tarnopolsky MA,Maguire J,Myint T,Applegarth D,Robinson BH

    更新日期:1998-01-01 00:00:00

  • Clinical and molecular aspects of the myotonic dystrophies: a review.

    abstract::Type 1 myotonic dystrophy or DM1 (Steinert's disease), which is the commonest muscular dystrophy in adults, has intrigued physicians for over a century. Unusual features, compared with other dystrophies, include myotonia, anticipation, and involvement of other organs, notably the brain, eyes, smooth muscle, cardiac co...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.20301

    authors: Machuca-Tzili L,Brook D,Hilton-Jones D

    更新日期:2005-07-01 00:00:00

  • Vibration injury damages arterial endothelial cells.

    abstract::Prolonged exposure to hand-transmitted vibration can cause debilitating neural and vascular dysfunction in humans. It is unclear whether the pathophysiology involves simultaneous or sequential injury of arteries and nerves. The mechanism of vibration injury was investigated in a rat tail model, containing arteries and...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.10058

    authors: Curry BD,Bain JL,Yan JG,Zhang LL,Yamaguchi M,Matloub HS,Riley DA

    更新日期:2002-04-01 00:00:00

  • Recurrent idiopathic lumbosacral plexopathy.

    abstract::Recurrent idiopathic lumbosacral plexopathy has rarely been reported in the literature. The present report describes a 59-year-old man presenting with recurrent episodes of acute leg pain, followed by weakness. After each episode, symptoms progressed for several months before peaking. Thereafter, gradual recovery ensu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/1097-4598(200009)23:9<1439::aid-mus18>3.0.

    authors: Yee T

    更新日期:2000-09-01 00:00:00

  • Three-dimensional topography of the motor endplates of the rat gastrocnemius muscle.

    abstract::Spatial distribution of motor endplates affects the shape of the electrical activity recorded from muscle. In order to provide information for realistic models of action potential propagation within muscles, we assembled three-dimensional maps of the motor endplates of the rat medial gastrocnemius (MGM) and lateral ga...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20378

    authors: Prodanov D,Thil MA,Marani E,Delbeke J,Holsheimer J

    更新日期:2005-09-01 00:00:00

  • Isometric contractions of normal and spastic human skeletal muscle.

    abstract::Isometric contractile properties of human elbow flexor muscles were examined in 27 normal subjects (7 females and 20 males). Contractions of elbow flexors were elicited by application of electrical pulses to the biceps motor points. The tension development was recorded at the wrist with the elbow angle fixed at 90 deg...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880040307

    authors: Ismail HM,Ranatunga KW

    更新日期:1981-05-01 00:00:00