当前位置： SCI文献检索 > JOURNAL OF CATARACT AND REFRACTIVE SURGERY期刊下所有文献 > Endothelial cell density after photorefractive keratectomy for moderate myopia using a 213 nm solid-state laser system.

Endothelial cell density after photorefractive keratectomy for moderate myopia using a 213 nm solid-state laser system.

Abstract：

PURPOSE:To evaluate whether photorefractive keratectomy (PRK) for moderate myopia using a solid-state laser with a wavelength of 213 nm alters the corneal endothelial cell density. SETTING:University refractive surgery center. METHODS:The corneal endothelium was analyzed preoperatively and 1, 6, and 12 months postoperatively using corneal confocal microscopy (modified HRT II with a Rostock Cornea Module, Heidelberg Engineering) in 60 eyes (30 patients). Patients were randomized to have myopic PRK using a 213 nm wavelength solid-state laser (study group) or a conventional 193 nm wavelength excimer laser (control group). Three endothelial images were acquired in each of 30 preoperative normal eyes to evaluate the repeatability of endothelial cell density measurements. Repeated-measures analysis of variance was used to compare the variations in endothelial cell density between the 2 lasers and the changes in endothelial cell density over time. RESULTS:There were no statistically significant differences in sex, age, corneal pachymetry, attempted correction, preoperative endothelial cell density, or postoperative refractive outcomes (uncorrected visual acuity, best spectacle-corrected visual acuity, and spherical equivalent refraction) between the 2 groups (P>.05). The coefficient of repeatability of endothelial cell density was 131 cells/mm(2). The measured endothelial cell count per 1.0 mm(2) did not significantly change up to 1 year postoperatively in either group (both P>.05). No statistically significant difference was found between the 2 groups in any postoperative interval (P>.05). CONCLUSION:Photorefractive keratectomy for moderate myopia using a 213 nm wavelength solid-state laser or a conventional 193 nm wavelength excimer laser did not significantly affect corneal endothelial density during the 1-year postoperative period.

journal_name

J Cataract Refract Surg

journal_title

Journal of cataract and refractive surgery

authors

Tsiklis NS,Kymionis GD,Pallikaris AI,Diakonis VF,Ginis HS,Kounis GA,Panagopoulou SI,Pallikaris IG

doi

10.1016/j.jcrs.2007.06.042

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

1866-70

issue

11

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(07)01356-9

journal_volume

33

pub_type

杂志文章,随机对照试验

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