Abstract：
PURPOSE:To determine the sex hormone levels in the serum and aqueous humor in patients with age-related cataract and the corresponding hormone receptors in cataract lens epithelial cells (LECs). SETTING:Research Laboratory, International Intraocular Implant Training Center, Tianjin Medical University, Tianjin, China. METHODS:Serum and aqueous humor were drawn from patients with cataract and a control group. Enzyme-linked immunosorbent assay was used to determine the levels of estradiol, progesterone, and testosterone in the serum and the aqueous. The anterior lens capsules with attached LECs were obtained during cataract surgery, and the expressions of estrogen receptor, progesterone receptor, or androgen receptor were examined by immunohistochemistry. RESULTS:The testosterone level in the serum was significantly higher in the control group than in the cataract group. In the cataract group, there was no difference between sexes in the serum levels of estradiol or progesterone; however, the testosterone level in men was significantly higher than in women. The aqueous level of each hormone was lower than in serum; however, there was no difference between sexes and no association with corresponding serum levels. No estrogen, progesterone, or androgen receptor was detected in the LECs of patients with age-related cataract. CONCLUSIONS:There was no statistical difference between men and women or between the cataract and control groups in the levels of estradiol or progesterone in serum. There was no between-sex difference in the aqueous levels. It appears that sex hormone levels can be regarded only as a risk factor for cataractogenesis, not as a key factor.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Zhang XH,Sun HM,Ji J,Zhang H,Ma WJ,Jin Z,Yuan JQdoi
10.1016/s0886-3350(02)01436-0subject
Has Abstractpub_date
2003-01-01 00:00:00pages
71-7issue
1eissn
0886-3350issn
1873-4502pii
S0886335002014360journal_volume
29pub_type
杂志文章abstract：PURPOSE:To evaluate a new diffractive multifocal intraocular lens (IOL) as an additional (add-on) IOL for sulcus-based implantation. SETTING:Augenklinik am Neumarkt, Köln, Germany. METHODS:In this prospective study, cataract patients had phacoemulsification and IOL implantation. After phacoemulsification, an aspheric...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2009.07.014
更新日期：2009-12-01 00:00:00
abstract：PURPOSE:To evaluate the repeatability and reproducibility of anterior chamber volume (ACV) measurements using swept-source 3-dimensional corneal and anterior segment optical coherence tomography (CAS-OCT) and dual Scheimpflug imaging. SETTING:Department of Ophthalmology, Institute of Clinical Medicine, University of T...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.jcrs.2010.08.053
更新日期：2011-03-01 00:00:00
abstract：:We describe a technique that prevents the Argentinean flag sign in white cataract. The technique is based on the intumescent cataract having 2 rather than 1 pressurized compartments within the crystalline lens, the anterior and the posterior. The pressure that pushes the nucleus upward, which is the movement responsib...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2012.07.002
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:To evaluate the change in higher-order aberrations (HOAs) after implantation of a foldable iris-claw phakic intraocular lens (pIOL) in myopic eyes. SETTING:Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany. METHODS:This prospective nonrandomized comparative self-controlled trial inclu...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.12.036
更新日期：2006-02-01 00:00:00
abstract：:To evaluate the biocompatibility of various materials including a poly(2-hydroxyethyl methacrylate [HEMA])/(6-hydroxyhexyl methacrylate [HOHEXMA]) hydrophilic hydrogel intraocular lens (IOL) (Hydroview, Bausch & Lomb). Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan. Ten opacified anterior ca...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(02)01988-0
更新日期：2003-06-01 00:00:00
abstract：:We modified our surgical techniques after analyzing the mechanisms responsible for posterior capsule-zonular disruption with or without vitreous loss in 250 consecutive extracapsular cataract extraction cases. We applied the derived principles and prospectively studied the subsequent 1,500 cases. Modifications in our ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80704-3
更新日期：1990-05-01 00:00:00
abstract：PURPOSE:To characterize the mean topographic shape of the limbus of a normal human eye and determine whether it depends on age or refractive power. SETTING:University of Manchester, Manchester, United Kingdom. DESIGN:Prospective case series. METHODS:Participants with no previous ocular surgeries were included in thi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.02.027
更新日期：2017-05-01 00:00:00
abstract：PURPOSE:To evaluate the safety and efficacy of a single perioperative sub-Tenon's injection of triamcinolone following cataract surgery and its effect on the incidence of early pseudophakic cystoid macular edema (CME). SETTING:Ophthalmology Department, Queen's Medical Centre University Hospital, Nottingham. United Kin...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2005.12.102
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:To present clinical findings of a cluster of cases of toxic anterior segment syndrome (TASS) after uneventful phacoemulsification cataract surgery. SETTING:Department of Ophthalmology, Akdeniz University, Antalya, Turkey. METHODS:Six eyes of 6 patients developed TASS after uneventful phacoemulsification catar...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.05.008
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:To investigate the clinical outcomes after implantation of a new hydrophobic acrylic intraocular lens (IOL) with hydroxyethyl methacrylate (HEMA) at 1 year and 9 years postoperatively. SETTING:Three surgical sites in Japan. DESIGN:Prospective case series and retrospective review. METHODS:In 110 eyes of 110 p...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000142
更新日期：2020-05-01 00:00:00
abstract：:A monolayer of proliferating lens epithelium on the anterior surface of an intraocular lens was found cytologically and confirmed histologically in a postmortem examination of one eye of a 57-year-old man. The man had had extracapsular cataract surgery five years earlier. This pathological finding confirms observation...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80353-7
更新日期：1993-11-01 00:00:00
abstract：PURPOSE:To describe a novel method for calculating intraocular lens (IOL) power after myopic laser in situ keratomileusis (LASIK) without using the inaccuracies of the post-LASIK corneal power. SETTING:Department of Ophthalmology, Wake Forest University Eye Center, Wake Forest University School of Medicine, Winston Sa...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.12.140
更新日期：2006-03-01 00:00:00
abstract：:Pediatric cataract surgery is challenging, with multiple differences from cataract surgery in adults; however, an ideal capsulorhexis is the major prerequisite for both. Capsulorhexis in children is more difficult due to the more elastic nature of the anterior capsule. I describe a technique for anterior and posterior...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2007.02.042
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:To evaluate alterations in corneal power parameters after Descemet-stripping automated endothelial keratoplasty (DSAEK) using rotating Scheimpflug imaging. SETTING:University of Texas, Southwestern Medical Center, Dallas, Texas, USA. METHODS:Eyes that had DSAEK were evaluated with a rotating Scheimpflug imagi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.01.032
更新日期：2010-08-01 00:00:00
abstract：:A study to determine the correlation between intraoperative quantitative keratometry and one day postoperative office keratometry was performed. Prior reports have failed to demonstrate a positive statistical relationship between surgical and postoperative keratometry, weakening the value of quantitative intraoperativ...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(88)80116-0
更新日期：1988-05-01 00:00:00
abstract：PURPOSE:To evaluate the levels of ischemia-modified albumin (IMA) in relation to oxidant-antioxidant profiles in the serum, aqueous, and lens in cataract patients. SETTING:Department of Ophthalmology, Menoufia University, Shebin El Kom, Menoufia, Egypt. DESIGN:Prospective case series. METHODS:Patients were divided i...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.10.051
更新日期：2018-02-01 00:00:00
abstract：:A 40-year old man, highly myopic in both eyes, had laser in situ keratomileusis (LASIK) in the left eye in November 1996. Corneal melting and ulceration and fine striae-like interface infiltrates were noticed 1 day postoperatively. There was no response to intensive topical antibiotics in the form of hourly ofloxacin ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(99)00080-2
更新日期：1999-07-01 00:00:00
abstract：:A 59-year-old patient who had photorefractive keratectomy (PRK) to correct high unilateral myopia developed a progressive nuclear cataract. Phacoemulsification and intraocular lens (IOL) implantation were performed. However, determination of IOL power using automated keratometry and computerized videokeratography was ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(99)80024-8
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:To evaluate the feasibility and safety of laser treatments in rabbit eyes fitted with an implantable miniature telescope (IMT). SETTING:The Goldschleger Eye Research Institute, Tel-Aviv University, Sheba Medical Center, Tel-Hashomer, Israel. METHODS:In this study, IMTs were implanted in the capsular bag in 19...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(02)01647-4
更新日期：2003-05-01 00:00:00
abstract：PURPOSE:To demonstrate the value, from the patient's perspective, of an apodized, diffractive, presbyopia-correcting multifocal intraocular lens (MF-IOL) compared to a conventional monofocal intraocular lens (CM-IOL). SETTING:Open-label, multi-site U.S. clinical trial. METHODS:A cost-benefit analysis was conducted us...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcrs.2008.07.024
更新日期：2008-11-01 00:00:00
abstract：:We received approval from the U.S. implant Food and Drug Administration and the University's Institutional Review Board to the Artisan lens (Ophtec BV) in both eyes of a patient who was aphakic and had megalocornea. No other intraocular lens would easily solve this patient's need because of the large anterior segment....
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.12.060
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:To analyze the repeatability of corneal astigmatism measurements with 2 autokeratometers (IOLMaster 500 and Lenstar LS 900), 2 Placido topographers (Keratron Scout and Atlas 9000), and a Scheimpflug tomographer (Pentacam HR). SETTING:Department of Ophthalmology, Goethe University, Frankfurt, Germany. DESIGN:P...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2015.11.046
更新日期：2016-04-01 00:00:00
abstract：:We report 2 patients who experienced progressive blurring of vision following myopic laser in situ keratomileusis (LASIK) in 1 eye (Case 1) and bilaterally (Case 2). High against-the-rule astigmatism, associated with perilimbal thinning inferiorly, was seen on refraction in all eyes. Regional corneal pachymetry confir...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00047-6
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:To use ultra-high-resolution optical coherence tomography (OCT) subclinical anatomic alterations to explain suboptimum vision despite pseudophakic cystoid macula edema (CME) resolution. SETTING:University of California-Davis, Sacramento, California, USA. DESIGN:Case study. METHODS:This study comprised patien...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2013.09.018
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:To compare corneal endothelial damage after cataract surgery in eyes with low endothelial cell density (ECD) and eyes with normal ECD. SETTING:Hayashi Eye Hospital, Fukuoka, Japan. DESIGN:Case-control study. METHODS:Cataract surgery was performed in eyes with a low ECD (500 to 1000 cells/mm(2)) (low-density ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2011.02.025
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:To report the results of transscleral implantation of foldable intraocular lenses (IOLs). SETTING:Department of Ophthalmology Dokuz Eylül University School of Medicine, Izmir, Turkey. METHODS:Twenty eyes of 20 patients had transscleral fixation of a foldable IOL combined with conventional 3-port pars plana vi...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2003.09.050
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:To examine the safety and efficacy of myopic keratomileusis in situ (automated lamellar keratoplasty) using an automated microkeratome. SETTING:Jules Stein Eye Institute and the Department of Ophthalmology, UCLA School of Medicine, Los Angeles, California. METHODS:A retrospective study was done on 135 consecu...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80145-3
更新日期：1996-12-01 00:00:00
abstract：:Four different posterior chamber lens designs were used in 1,845 consecutive, unselected extracapsular cataract extractions performed over a 31-month period in Vejle, Denmark. Ninety-seven eyes (5.3%) required a posterior capsulotomy during a postoperative observation period ranging from two to 32 months. At 16 months...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(88)80143-3
更新日期：1988-07-01 00:00:00
abstract：PURPOSE:To compare the incidence and severity of photic phenomena after the implantation of the Array(R) (Allergan) refractive multifocal intraocular lens (MIOL) and a monofocal IOL. SETTING:Multicenter study at Kiel, Mainz, Karlsruhe, and Bremerhaven, Germany. METHODS:The study comprised 231 randomly selected patien...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0886-3350(00)00540-x
更新日期：2001-02-01 00:00:00
abstract：PURPOSE:To evaluate the feasibility and risks of primary posterior capsulorhexis. SETTING:Department of Ophthalmology, University Hospital of Liège, Belgium. METHODS:Retrospective analysis of 319 patients with cataracts who had phacoemulsification or manual extracapsular cataract extraction with a simultaneous circul...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80042-3
更新日期：1996-05-01 00:00:00
