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Cataract surgery in eyes with low corneal endothelial cell density.

Abstract：

PURPOSE:To compare corneal endothelial damage after cataract surgery in eyes with low endothelial cell density (ECD) and eyes with normal ECD. SETTING:Hayashi Eye Hospital, Fukuoka, Japan. DESIGN:Case-control study. METHODS:Cataract surgery was performed in eyes with a low ECD (500 to 1000 cells/mm(2)) (low-density group) and control eyes with a normal ECD. The ECD and central corneal thickness (CCT) were measured preoperatively and 1 and 3 months postoperatively, and the percentage cell loss and increase in CCT were compared. RESULTS:The low-density group and control group each comprised 50 eyes. In the low-density group, 39 eyes had nonprogressive endothelial pathology and 11 had Fuchs dystrophy. The mean ECD was significantly less and the CCT significantly greater in the low-density group than in the control group throughout the follow-up (P ≤.0066). However, no significant difference in the percentage of cell loss was found between groups at 1 or 3 months (5.1%, low-density group; 4.2%, control group) (P ≥.1477). The percentage increase in CCT was significantly greater in the low-density group than in the control group at 1 month (P<.0001), although there was no significant difference at 3 months (0.4% and -0.4%, respectively) (P=.2172). CONCLUSION:Corneal endothelial damage after cataract surgery in eyes with low ECD was slight and comparable to that in healthy eyes, which suggests that cataract surgery alone (without corneal transplantation) should be performed first.

journal_name

J Cataract Refract Surg

journal_title

Journal of cataract and refractive surgery

authors

Hayashi K,Yoshida M,Manabe S,Hirata A

doi

10.1016/j.jcrs.2011.02.025

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

1419-25

issue

8

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(11)00721-8

journal_volume

37

pub_type

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