Abstract:
PURPOSE:To evaluate the safety of a new suprachoroidal device, the Cypass micro-stent, for the surgical treatment of open-angle glaucoma (OAG) implanted in conjunction with cataract surgery. SETTING:Multicenter clinical study. DESIGN:Prospective interventional case series. METHODS:This is an interim report of an ongoing safety study. Patients with OAG glaucoma (Shaffer grade 3 and 4) who were also candidates for cataract surgery in the affected eye had standard phacoemulsification followed by micro-stent implantation in the supraciliary space. Included were patients with uncontrolled (≥ 21 mm Hg, Cohort 1) or controlled (<21 mm Hg, Cohort 2) medicated intraocular pressure (IOP) at baseline. Glaucoma medications were discontinued at surgery and resumed at the discretion of each investigator. Measures included adverse events/complications and postoperative changes in IOP or medication. RESULTS:The mean baseline medicated IOP was 21.1 mm Hg ± 5.91 (SD); the mean number of IOP-lowering medications was 2.1 ± 1.1 (N = 184). There were no major events such as retinal or choroidal detachment or endophthalmitis. The most common complications were transient early hypotony (13.8%) and transient IOP increase (10.5%). Uncontrolled patients (n = 57) had a 37% IOP reduction (P<.001), with more than a 50% reduction in glaucoma medications at 6 months (P<.001). Intraocular pressure-controlled patients (n = 41) had a 71.4% reduction in glaucoma medications (P<.001). CONCLUSION:Initial clinical experience with the new micro-stent showed a low rate of surgical complications with concomitant decreases in IOP and/or glaucoma medications.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Hoeh H,Ahmed II,Grisanti S,Grisanti S,Grabner G,Nguyen QH,Rau M,Yoo S,Ianchulev Tdoi
10.1016/j.jcrs.2012.10.040subject
Has Abstractpub_date
2013-03-01 00:00:00pages
431-7issue
3eissn
0886-3350issn
1873-4502pii
S0886-3350(12)01571-4journal_volume
39pub_type
杂志文章,多中心研究abstract:PURPOSE:To evaluate the actual versus the expected thickness of laser in situ keratomileusis (LASIK) flaps and to determine the factors that affect flap thickness. SETTING:Centre For Sight, Queen Victoria Hospital, East Grinstead, United Kingdom. METHODS:A retrospective analysis of LASIK procedures in 757 consecutive...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2003.09.070
更新日期:2004-05-01 00:00:00
abstract::Anterior segment optical coherence tomography is a new method to explore the anterior chamber. The target can be focused and defocused with positive or negative lenses to reproduce the conditions of natural accommodation. We studied accommodation in an albino patient because the absence of pigment allows the infrared ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2003.12.043
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:To identify potential risk factors associated with post-cataract surgery bacterial endophthalmitis. SETTING:The John A. Moran Eye Center, Salt Lake City, Utah, USA. METHODS:This retrospective cohort study consisted of patients who had surgery for cataract(s) at this eye hospital. A 10% sampling of all patient...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2004.10.057
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To study the safety of irrigation with 5-fluorouracil (5-FU) in the Perfect Capsule sealed-capsule irrigation device (Milvella, Ltd., Epping, Australia). SETTING:St. Erik's Eye Hospital, Stockholm, Sweden. METHODS:Thirty 8-week-old rabbits were divided into 4 groups. Clear lens extraction was performed and th...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2007.05.012
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:To define one possible etiology for the rise in intraocular pressure (IOP) after neodymium: YAG (Nd:YAG) laser capsulotomy and provide information for the continued investigation of this process. SETTING:Laser Center, Eye and Ear Institute, Pittsburgh, Pennsylvania. METHODS:Samples of 1% sodium hyaluronate or...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(96)80315-4
更新日期:1996-07-01 00:00:00
abstract::Several transscleral suturing techniques require intricate surgical maneuvers and are associated with an increased risk for surgical trauma. We describe a new scleral fixation method that combines the advantages of temporary haptic externalization and injector implantation of an intraocular lens (IOL). After IOL inser...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.11.030
更新日期:2010-05-01 00:00:00
abstract::An 80-year-old woman of mixed ethnicity developed significant iris transillumination defects following phacoemulsification with in-the-bag implantation of a single-piece hydrophobic acrylic intraocular lens (IOL) and trabeculectomy with insertion of an Express mini-shunt. With the exception of modest anterior chamber ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2012.10.014
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To compare the photopic and scotopic contrast sensitivity with and without glare as well as blue color perception between eyes with an AcrySof SN60AT Natural intraocular lens (IOL) (Alcon Laboratories Inc.) and eyes with a conventional AcrySof SA60AT IOL. SETTING:Ankara University School of Medicine, Departmen...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2006.12.018
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To evaluate the prophylactic effect of levobunolol 0.5%, timolol 0.5%, or vehicle in reducing the incidence of postoperative intraocular pressure (IOP) spikes of 5 and 10 mm Hg or more in patients having neodymium:YAG (Nd:YAG) laser posterior capsulotomy. SETTING:Miami Vision Center, Coral Gables, Florida; Cul...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(97)80083-1
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:To evaluate the effect of removal and/or exchange of intrastromal corneal ring segments (ICRS, Intacs); specifically the risk factors, degree of reversibility, and visual outcomes. SETTING:Gimbel Eye Centres, Calgary, Edmonton, and Vancouver, Canada. METHODS:Prospective cohort data were collected on 71 eyes t...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(01)01172-5
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:To evaluate and compare the incidence of cyanopsia using the neutralization method in eyes in which clear or yellow intraocular lenses (IOLs) were implanted. SETTING:Miyata Eye Clinic, Hiroshima, Japan. DESIGN:Retrospective comparative study. METHODS:Patients who had cataract surgery with the implantation of...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2014.07.040
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:To compare endothelial damage induced by different cataract incision sites and sizes using specular microscopy. SETTING:Department of Ophthalmology, Hospital of San Donà di Piave, Venice, Italy. METHODS:Eighty-one eyes having phacoemulsification were randomly assigned to 1 of 3 groups of 27 eyes each: 3.5 mm ...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0886-3350(01)00983-x
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of Intacs inserts in keratoconic eyes to alter corneal shape and refractive power and stabilize the progression of corneal ectasia. SETTING:Service d'Ophtalmologie, Bordeaux, France. METHODS:In this prospective study, 57 eyes with clear central corneas that were diagnosed w...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcrs.2006.01.064
更新日期:2006-05-01 00:00:00
abstract::We describe a case of corneal chromoblastomycosis with Cladophialophora carrionii in a 69-year-old woman 4 weeks after clear corneal cataract surgery. The patient presented with right eye pain and decreased visual acuity of 20/100. Examination showed a deep posterior stromal keratitis accompanied by a dense fibrinous ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2011.03.007
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To demonstrate the value, from the patient's perspective, of an apodized, diffractive, presbyopia-correcting multifocal intraocular lens (MF-IOL) compared to a conventional monofocal intraocular lens (CM-IOL). SETTING:Open-label, multi-site U.S. clinical trial. METHODS:A cost-benefit analysis was conducted us...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcrs.2008.07.024
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To evaluate irregularity of the anterior and posterior cornea before and after Descemet-stripping endothelial keratoplasty (DSEK) and its effect on visual acuity. SETTING:Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. METHODS:Corneal data were acquired using a rotating Scheimpf...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2008.11.062
更新日期:2009-04-01 00:00:00
abstract:PURPOSE:To evaluate the agreement of ocular measurements obtained with a new optical biometer (AL-Scan) and a previously validated optical biometer (Lenstar). SETTING:Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. DESIGN:Prospective observational cross-sectional study. METHODS:For a comprehens...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2015.05.042
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To evaluate the intraoperative difficulties and long-term outcome of phacoemulsification through a small pupil using minimal iris manipulation. SETTINGS:Iladevi Cataract & IOL Research Centre, Ahmedabad, India. METHODS:This prospective study included 30 consecutive eyes with a maximally dilated pupil size of ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(00)00361-8
更新日期:2000-08-01 00:00:00
abstract::Contrast sensitivity was measured in 25 patients who had a multifocal diffractive intraocular lens and in 23 control patients with a monofocal lens in four simulated light conditions: (1) daylight, (2) daylight with peripheral glare, (3) twilight, (4) twilight with central glare. In normal daylight and twilight, contr...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(13)80952-2
更新日期:1993-03-01 00:00:00
abstract:PURPOSE:To evaluate the feasibility and risks of primary posterior capsulorhexis. SETTING:Department of Ophthalmology, University Hospital of Liège, Belgium. METHODS:Retrospective analysis of 319 patients with cataracts who had phacoemulsification or manual extracapsular cataract extraction with a simultaneous circul...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(96)80042-3
更新日期:1996-05-01 00:00:00
abstract:PURPOSE:To investigate the position of 3-piece foldable intraocular lenses (IOLs) after piggyback implantation for high hyperopia. SETTING:University Eye Hospital, Johann Wolfgang Goethe University, Frankfurt am Main, Germany. METHODS:Eight eyes of 5 highly hyperopic patients had phacoemulsification and implantation ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2006.08.033
更新日期:2006-12-01 00:00:00
abstract::A 60-year-old white man had cataract surgery with an AcrySof IQ intraocular lens (IOL) implanted in the right eye and a Tecnis IOL implanted in the left eye. The ocular spherical aberration (SA) target for a 6.0 mm pupil was +0.10 microm for the right eye and 0 microm for the left eye. After surgery, the ocular SA in ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2008.12.041
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:To study prospectively the success rate and complications of deep sclerectomy with collagen implant (DSCI), a nonpenetrating filtration procedure. SETTING:Glaucoma Unit, Department of Ophthalmology, Hôpital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland. METHODS:This nonrandomized pros...
journal_title:Journal of cataract and refractive surgery
pub_type: 临床试验,杂志文章
doi:10.1016/s0886-3350(01)01032-x
更新日期:2001-11-01 00:00:00
abstract::We report 2 cases of reopening of macular holes after successful neodymium:YAG (Nd:YAG) posterior capsulotomy. Both patients had surgery for closure of macular holes with recovery of visual acuity. To our knowledge, this is the first report of recurrent macular holes after Nd:YAG laser posterior capsulotomy treated su...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2005.07.020
更新日期:2006-02-01 00:00:00
abstract::Intraocular metallic-appearing foreign bodies in the anterior segment were seen in six eyes after cataract extraction by two-handed phacoemulsification. These fragments produced no symptoms and had no clinically significant effect on visual function. Similar-appearing foreign bodies were experimentally produced by app...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/s0886-3350(96)80078-2
更新日期:1996-11-01 00:00:00
abstract:PURPOSE:To evaluate the repeatability of the Galilei dual-Scheimpflug analyzer in measuring corneal curvature, wavefront aberrations, pachymetry, and anterior chamber depth (ACD). SETTING:Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA. METHODS:Three consecutive measurements were performed in 1 ...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.09.034
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To compare the accuracy of a handheld infrared digital pupillometer and digital infrared photography for measurement of the dark-adapted pupil diameter. SETTING:Department of Ophthalmology and Visual Sciences, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. METHODS:The right horizontal pupi...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2009.09.025
更新日期:2010-02-01 00:00:00
abstract:PURPOSE:To investigate preoperative and postoperative prophylactic treatment with different pharmacological agents before flap cutting and exposure to a diffuse lamellar keratitis (DLK) causative agent. SETTING:Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Cha...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/S0886-3350(03)00327-4
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To compare higher-order aberrations (HOAs) and visual function in eyes with a toric intraocular lens (IOL) and eyes with a nontoric IOL. SETTING:Hayashi Eye Hospital, Fukuoka, Japan. DESIGN:Case-control study. METHODS:Eyes that had phacoemulsification were enrolled in 1 of the following 3 groups: (1) preoper...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2012.02.032
更新日期:2012-07-01 00:00:00
abstract:PURPOSE:To devise a comprehensive cataract surgery complexity score system for the selection of appropriate cases for trainees using evidence-based, validated risk factors for posterior capsule rupture, patient-specific factors, and complexity stratification recommendations to minimize complications, optimize outcomes,...
journal_title:Journal of cataract and refractive surgery
pub_type: 杂志文章
doi:10.1016/j.jcrs.2018.04.036
更新日期:2018-06-01 00:00:00