Abstract：
PURPOSE:To evaluate whether laser-assisted subepithelial keratectomy (LASEK) achieves effective targeted myopic correction with less post-treatment corneal haze than observed with photorefractive keratectomy (PRK) in children who fail traditional forms of treatment for myopic anisometropic amblyopia and high myopia. SETTING:Nonhospital surgical facility with follow-up in a hospital clinic setting. METHODS:This prospective study comprised 36 eyes of 25 patients. The mean patient age at treatment was 8.27 years (range 1.0 to 17.4 years). Patients were divided into 3 groups: those with myopic anisometropic amblyopia (13 patients/13 eyes), those with bilateral high myopia (11 patients/22 eyes), and those with high myopia post-penetrating keratoplasty (1 patient/1 eye). All patients were treated with LASEK under general anesthesia using the Visx 20/20 B excimer laser and a multizone, multipass ablation technique. Although the myopia was as high as -22.00 diopters (D) spherical equivalent (SE) in some eyes, no eye was treated for more than -19.00 D SE. RESULTS:At 1 year, the mean SE decreased from -8.03 D to -1.19 D. Forty-four percent of eyes were within +/-1.0 D of the targeted correction; 78% of eyes had clear corneas with no haze. In the entire group, the mean best corrected visual acuity improved from 20/80 to 20/50. A functional-vision survey demonstrated a positive effect on the patients' ability to function in their environments after LASEK. CONCLUSIONS:Laser-assisted subepithelial keratectomy in children represents another method of providing long-term resolution of bilateral high myopia and myopic anisometropic amblyopia with minimal post-laser haze. The reduction in post-laser haze with LASEK compared to that with the standard PRK technique may represent an advantage in treating these complex patients.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Astle WF,Huang PT,Ingram AD,Farran RPdoi
10.1016/j.jcrs.2004.06.025subject
Has Abstractpub_date
2004-12-01 00:00:00pages
2529-35issue
12eissn
0886-3350issn
1873-4502pii
S0886-3350(04)00624-8journal_volume
30pub_type
杂志文章abstract：:We describe a technique to prevent late intraocular lens (IOL) subluxation and dislocation that can be associated with progressive zonulopathy. Supracapsular glued IOL fixation is done to retain an intact anterior hyaloid face and avoid vitreous disturbance while providing stable long-term IOL fixation. Phacoemulsific...
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journal_title：Journal of cataract and refractive surgery
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journal_title：Journal of cataract and refractive surgery
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journal_title：Journal of cataract and refractive surgery
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更新日期：1994-09-01 00:00:00
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journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2002-03-01 00:00:00
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journal_title：Journal of cataract and refractive surgery
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journal_title：Journal of cataract and refractive surgery
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journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
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更新日期：2003-09-01 00:00:00
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更新日期：2009-10-01 00:00:00
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pub_type： 临床试验,杂志文章
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journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
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journal_title：Journal of cataract and refractive surgery
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更新日期：1998-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2015-12-01 00:00:00
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journal_title：Journal of cataract and refractive surgery
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更新日期：2005-05-01 00:00:00
