Abstract：
PURPOSE:To measure the inflammatory reaction in the anterior chamber after lens extraction in a rabbit model and to evaluate the effect of nonsteroidal antiinflammatory drugs (NSAIDs) or steroids on the amount of inflammation as measured by fibrinogen levels in the aqueous humor. SETTING:Animal laboratory, Goldschleger Research Institute, Tel Aviv University, Sheba Medical Center, Ramat Gan, Israel. DESIGN:Experimental study. MATERIALS:Twenty-six eyes of New Zealand white rabbits had lens extraction surgery. One day later, aqueous humor (∼0.1 mL) was withdrawn from the anterior chamber and examined for fibrinogen concentration. Control rabbits received no treatment (9 eyes) or artificial tear eyedrops (5 eyes). One study group received NSAID drops (diclofenac) (6 eyes), and another study group received steroid drops (dexamethasone-neomycin) (6 eyes). All rabbits were treated hourly for 9 applications. Aqueous humor (∼0.1 mL) was withdrawn from the anterior chamber and examined for fibrinogen concentration 1 day later. Fibrinogen levels were also measured in the aqueous in 8 unoperated eyes. RESULTS:Steroid-treated eyes achieved the lowest inflammatory score, followed by NSAID eyes, artificial tears eyes, and untreated eyes. The mean fibrinogen concentrations in the aqueous humor were 69.1 mg% untreated, 52.0 mg% artificial tears, 18.5 mg% NSAIDs, and 2.8 mg% steroids (P=.002). CONCLUSIONS:Measurement of aqueous fibrinogen after lens extraction surgery in a rabbit animal model was simple and provided a useful parameter for precise evaluation of postoperative intraocular reaction. Steroids and NSAIDs were effective in reducing postoperative inflammation. Steroids reduced inflammation to almost undetectable values. FINANCIAL DISCLOSURE:No author has a financial or proprietary interest in any material or method mentioned.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Ben Simon GJ,Kenet G,Spierer Adoi
10.1016/j.jcrs.2011.12.026subject
Has Abstractpub_date
2012-05-01 00:00:00pages
890-3issue
5eissn
0886-3350issn
1873-4502pii
S0886-3350(12)00283-0journal_volume
38pub_type
杂志文章abstract：:A 40-year old man, highly myopic in both eyes, had laser in situ keratomileusis (LASIK) in the left eye in November 1996. Corneal melting and ulceration and fine striae-like interface infiltrates were noticed 1 day postoperatively. There was no response to intensive topical antibiotics in the form of hourly ofloxacin ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(99)00080-2
更新日期：1999-07-01 00:00:00
abstract：:We modified our surgical techniques after analyzing the mechanisms responsible for posterior capsule-zonular disruption with or without vitreous loss in 250 consecutive extracapsular cataract extraction cases. We applied the derived principles and prospectively studied the subsequent 1,500 cases. Modifications in our ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80704-3
更新日期：1990-05-01 00:00:00
abstract：PURPOSE:To evaluate a new diffractive multifocal intraocular lens (IOL) as an additional (add-on) IOL for sulcus-based implantation. SETTING:Augenklinik am Neumarkt, Köln, Germany. METHODS:In this prospective study, cataract patients had phacoemulsification and IOL implantation. After phacoemulsification, an aspheric...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2009.07.014
更新日期：2009-12-01 00:00:00
abstract：:This report details the case of a 65-year-old man with advanced cataract in which there was a large discrepancy between the K-readings taken with a keratometer and those taken with a TMS-1 videokeratoscope. It was suspected the discrepancy was caused by the advanced cataract in the presence of a dilated pupil. Repeat ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80155-6
更新日期：1996-12-01 00:00:00
abstract：PURPOSE:To evaluate the long-term response of 6 types of 3-piece intraocular lenses (IOLs) by assessing the cellular reaction on the anterior IOL surface, the behavior of posterior and anterior capsule fibrosis, and flare. SETTING:Department of Ophthalmology, Medical School, University of Vienna, Vienna, Austria. MET...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(01)01122-1
更新日期：2002-01-01 00:00:00
abstract：PURPOSE:To compare loteprednol etabonate (LE) gel 0.5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children. SETTING:Eleven sites in the United States. DESIGN:Randomized, double-masked, parallel-group, noninferiority study. METHODS:Eligible patients were a...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000218
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:To describe the use of a motorized milling drill to perform nonpenetrating glaucoma surgery and to assess its safety. SETTING:Instituto Oftalmológico de Alicante, Miguel Hernandez University, School of Medicine, Alicante, Spain. METHODS:This prospective noncomparative study included 16 eyes (13 patients) diag...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2003.11.052
更新日期：2004-07-01 00:00:00
abstract：PURPOSE:To assess visual acuity tolerance to defocus caused by residual refractive errors after clear lens extraction (CLE) with apodized diffractive intraocular lens (IOL) implantation. SETTING:Fernández-Vega Ophthalmological Institute, Oviedo, Spain. METHODS:In this prospective study, 150 eyes of 75 consecutive pat...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2007.10.020
更新日期：2008-02-01 00:00:00
abstract：:Two cases of intrastromal corneal ring (Intacs, Addition Technology) implantation to treat post-laser in situ keratomileusis (LASIK) ectasia developed progressive slippage of the flap over the stromal bed, resulting in progressive flattening of the affected meridian. The flattening was thought to have occurred because...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.06.049
更新日期：2008-12-01 00:00:00
abstract：PURPOSE:To test the performance of 4 tonometers in estimating intraocular pressure (IOP) after 3 forms of refractive surgery. SETTING:Eye Hospital, Wenzhou Medical University, China. DESIGN:Prospective case series. METHODS:Patients matched for preoperative age, corneal thickness, and myopic correction enrolled for f...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000204
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To study the effect of primary posterior capsulotomy with anterior vitrectomy (PPC + AV) and intraocular lens (IOL) design and material on the development of posterior capsule opacification (PCO) after pediatric cataract surgery. SETTING:Tertiary care institution in India. PATIENTS:Sixty-four eyes of 52 child...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00231-1
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:To evaluate findings of reverse pupillary block after scleral-fixated sutured posterior chamber intraocular lens (PC IOL) implantation using anterior segment optical coherence tomography (AS-OCT) and report a possible association with postoperative complications. SETTING:Department of Ophthalmology, Kanazawa U...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.04.030
更新日期：2009-09-01 00:00:00
abstract：:A 31-year-old woman developed pain, decreased vision, and a corneal flap infiltrate 4 days following laser in situ keratomileusis (LASIK). Treatment with topical antibiotic agents did not improve the symptoms. Approximately 2 weeks after surgery, the patient was referred to Stanford University, with 20/400 visual acui...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2007.05.051
更新日期：2007-10-01 00:00:00
abstract：PURPOSE:To delineate the learning curve for a beginning refractive surgeon using the centrifugal (American) technique. SETTING:Naval Medical Center, San Diego, California, USA. METHODS:The first 100 radial keratotomy (RK) cases (51 patients) of one surgeon, divided into five sequential groups of 20, were retrospectiv...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(98)80286-1
更新日期：1998-04-01 00:00:00
abstract：:Over a 12 month period, we used the anterior chamber maintainer (ACM) in cataract surgery in 258 patients; ages ranged from 15 to 95 years (mean 73 years). Surgery was performed using general or local anesthesia. The procedures were standard extracapsular cataract extraction (ECCE), mini-nuc ECCE, vectis extraction of...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80214-8
更新日期：1996-03-01 00:00:00
abstract：:Over 100 cases of standard extracapsular cataract extraction with intraocular lens implantation were reviewed and the effects of two commercially available pharmacological agents were compared. The treatment groups received either acetylcholine chloride (Miochol) or carbachol (Miostat). Intraocular pressures were meas...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(89)80008-2
更新日期：1989-03-01 00:00:00
abstract：:We report 2 cases of serous macular detachment with intraretinal fluid accumulation that developed 1 day after uneventful phacoemulsification surgery. Because of a dilution error, both eyes received 2 mg/0.1 mL of intracameral cefuroxime at the end of surgery. On postoperative day 1, the corrected distance visual acui...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.07.007
更新日期：2010-11-01 00:00:00
abstract：:A 25-year-old woman with moderate myopia presented for refractive surgery. Bilateral femtosecond laser-assisted small-incision lenticule extraction (SMILE) was scheduled and her right eye was completed smoothly. However, during the lenticule cutting of her left eye, a large inferior black area was noted. The operation...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000185
更新日期：2020-06-01 00:00:00
abstract：:Descemet-stripping automated endothelial keratoplasty (DSAEK) is an alternative to penetrating keratoplasty for the treatment of corneal endothelial disease that involves stripping diseased Descemet membrane (DM) from the recipient. Descemet membrane stripping is currently performed with a generic balanced salt soluti...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.01.037
更新日期：2008-06-01 00:00:00
abstract：:We used the finite element method to evaluate different capsulotomy techniques. Nucleus expression was simulated in a computer model to visualize stress distribution in the anterior capsule. The finite element model demonstrated that the capsulorhexis edge is strong because of low and uniform stress distribution in th...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80176-9
更新日期：1994-07-01 00:00:00
abstract：:We report a case of late-onset diffuse lamellar keratitis (DLK) in the left eye of a 56-year-old white woman 3 years after uneventful bilateral laser in situ keratomileusis (LASIK). Slitlamp examination revealed stage 3 DLK with diffuse, multifocal, dot-like, and granular haze in the interface. The DLK did not have an...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.05.054
更新日期：2005-02-01 00:00:00
abstract：:A retrospective analysis of 40 cases of sulcus-fixated one-piece poly(methyl methacrylate) posterior chamber lenses revealed ten cases (25%) that demonstrated oval deformation of the pupil, similar to the condition associated with anterior chamber lenses. This complication was not noted until several weeks after surge...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80803-6
更新日期：1990-07-01 00:00:00
abstract：:A 43-year-old white woman with a history of multiple ocular surgeries, including 4 penetrating keratoplasties, developed a concentric retrocorneal membrane at the graft periphery in the right eye. A white-light, tandem, scanning confocal microscope using a 24x/0.60 contact objective was used to examine the right eye i...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(99)00133-9
更新日期：1999-08-01 00:00:00
abstract：:Corectopia, the eccentric displacement of the pupil, may be associated with other abnormalities such as axial high myopia or ectopia lentis. We report the case of a patient presenting for surgery to correct bilateral myopia of 6.50 diopters (D) associated with corectopia. Excimer laser ablation was decentered and perf...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(99)00018-8
更新日期：1999-05-01 00:00:00
abstract：:Two patients with active iritis developed cataracts and had successful cataract surgery with implantation of a Collamer (Staar Surgical, AG) intraocular lens (IOL). Both patients developed severe bilateral uveitis, which in 1 patient was refractory to control. Different IOL materials have been used in iritis patients ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00329-8
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:To compare the postoperative blood-aqueous barrier (BAB) breakdown induced by phacoemulsification with continuous curvilinear capsulorhexis (CCC) and by extracapsular cataract extraction (ECCE) with a linear capsulotomy. SETTING:Cataract and Refractive Surgery Research Unit, Department of Ophthalmology, St. Th...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80160-x
更新日期：1996-01-01 00:00:00
abstract：UNLABELLED:A 22-year-old white man presented with photopsia of 3-year duration despite a corrected distance visual acuity of 20/20 in both eyes. Ophthalmic examination revealed multiple irregularly shaped white cortical opacifications of the lens in both eyes but no other significant ocular findings. One year after the...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.06.007
更新日期：2016-07-01 00:00:00
abstract：:We report a case of bilateral infectious keratitis occurring as a complication of bilateral simultaneous laser in situ keratomileusis enhancement procedures. Corneal scraping from the interface of both eyes grew Staphylococcus aureus. The infection cleared after treatment with fortified cefazolin, fortified gentamicin...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(01)01232-9
更新日期：2002-04-01 00:00:00
abstract：PURPOSE:To compare the effectiveness of 2 medications commonly used to prevent intraocular pressure (IOP) elevation in the early period after cataract surgery. SETTING:Palo Alto Veterans Affairs Health Care System, Palo Alto, California, USA. METHODS:This prospective study comprised 202 eyes of patients scheduled for...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(98)80172-7
更新日期：1998-11-01 00:00:00
abstract：PURPOSE:To compare the development of posterior capsule opacification (PCO) and neodymium:YAG (Nd:YAG) capsulotomy rates between 2 microincision intraocular lenses (IOLs) 4 years after surgery. SETTING:Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. DESIGN:Prospective randomized clinical t...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jcrs.2014.09.037
更新日期：2015-05-01 00:00:00
