Effect of peripheral trifluoromethyl groups in artificial iron porphycene cofactor on ligand binding properties of myoglobin.

abstract：:the reactions of chloroauric acid (HAuCl4) with inosine=ino, guanosine=guo, triacetylinosine=trino, triacetylguanosine=trguo, and cytidine=cyd were studied. Complexes of AU(III) and AU(I) with these nucleosides have been isolated from the reactions at different pH values in aqueous and in methanolic solutions. The Au(...

journal_title：Journal of inorganic biochemistry

authors： Hadjiliadis N,Pneumatikakis G,Basosi R

更新日期：1981-04-01 00:00:00

abstract：:The interactions of proteins with reactive oxygen species (ROS) may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages, and oxidation of the protein backbone resulting in protein fragmentation. In an attempt to elucidate the products of the metal-catalyzed ...

journal_title：Journal of inorganic biochemistry

authors： Kowalik-Jankowska T,Ruta M,Wiśniewska K,Łankiewicz L,Dyba M

更新日期：2004-06-01 00:00:00

abstract：:The cysteine proteases of the trypanosomatid parasitic protozoa have been validated as targets for chemotherapy of Chagas' disease and leishmaniasis. Metal complexes of gold, platinum, iridium, palladium, rhodium and osmium have been reported to have activity against a variety of trypanosomatids, but the molecular tar...

journal_title：Journal of inorganic biochemistry

authors： Fricker SP,Mosi RM,Cameron BR,Baird I,Zhu Y,Anastassov V,Cox J,Doyle PS,Hansell E,Lau G,Langille J,Olsen M,Qin L,Skerlj R,Wong RS,Santucci Z,McKerrow JH

更新日期：2008-10-01 00:00:00

abstract：:4-(2-Pyridylazo)resorcinol (PAR) is one of the most popular chromogenic chelator used in the determination of the concentrations of various metal ions from the d, p and f blocks and their affinities for metal ion-binding biomolecules. The most important characteristics of such a sensor are the molar absorption coeffic...

journal_title：Journal of inorganic biochemistry

authors： Kocyła A,Pomorski A,Krężel A

更新日期：2015-11-01 00:00:00

abstract：:Iron deficiency anemia is a relatively common illness that can arise from a number of different causes. Three ferrous salts are usually used in its treatment: ferrous fumarate, gluconate, and sulfate. They are administered orally and are relatively well tolerated. These hematinics have been studied by Mössbauer spectr...

journal_title：Journal of inorganic biochemistry

authors： Coe EM,Bowen LH,Bereman RD

更新日期：1995-06-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an alternative treatment widely used against cancer. PDT requires molecular systems, known as photosensitizers (PS), which not only exhibit strong absorption at a particular wavelength range, but also need to be selectively accumulated inside cancer cells. PS are activated by specific wav...

journal_title：Journal of inorganic biochemistry

authors： Noriega L,Castro ME,Perez-Aguilar JM,Caballero NA,Sanchez-Gaytan BL,González-Vergara E,Melendez FJ

更新日期：2020-02-01 00:00:00

abstract：:Measurement and interpretation of the EXAFS associated with the K-absorption edge of zinc atoms in sheep liver metallothionein indicate that the primary coordination shell of each of these metal atoms comprises four sulphur atoms, with the Zn-S distance being 2.29 +/- 0.02 A. ...

journal_title：Journal of inorganic biochemistry

authors： Garner CD,Hasain SS,Bremner I,Bordas J

更新日期：1982-06-01 00:00:00

abstract：:The study of the metal binding pattern of N-methyladenines (1-, 3-, 7- or 9-Meade) towards CuII-iminodiacetate-like chelates is addressed on the basis of XRD crystal structures of sixteen novel ternary compounds. Except for three compounds, all others feature an square-based Cu(II) coordination, type 4 + 1, and the ef...

journal_title：Journal of inorganic biochemistry

authors： García-Rubiño ME,Barceló-Oliver M,Castiñeiras A,Domínguez-Martín A

更新日期：2019-11-01 00:00:00

abstract：:A kinetic study of CO(2) hydration was carried out using the water-soluble zinc model complex with water-soluble nitrilotris(2-benzimidazolylmethyl-6-sulfonate) L1S, [L1SZn(OH(2))](-), mimicking the active site of carbonic anhydrase, in the presence and absence of anion inhibitors NCS(-) and Cl(-). The obtained rate c...

journal_title：Journal of inorganic biochemistry

authors： Nakata K,Shimomura N,Shiina N,Izumi M,Ichikawa K,Shiro M

更新日期：2002-04-28 00:00:00

abstract：:Composites of beta-chitin with calcium carbonate polymorphs were prepared by precipitation of the mineral into a chitin scaffold by means of a double diffusion system. The beta-chitin was obtained from the pen of the Loligo sp. squid. The three main polymorphs of calcium carbonate: aragonite, calcite and vaterite, wer...

journal_title：Journal of inorganic biochemistry

authors： Falini G,Fermani S,Ripamonti A

更新日期：2002-08-30 00:00:00

abstract：:The interaction of V(IV)O-salts as well as of a few V(IV)O(carrier)n complexes with human serum transferrin (hTF) is studied focusing on the determination of the nature and stoichiometry of the binding of V(IV)O(2+) to hTF, as well as whether the conformation of hTF upon binding to V(IV)O(2+) or to its complexes is ch...

journal_title：Journal of inorganic biochemistry

authors： Mehtab S,Gonçalves G,Roy S,Tomaz AI,Santos-Silva T,Santos MF,Romão MJ,Jakusch T,Kiss T,Pessoa JC

更新日期：2013-04-01 00:00:00

abstract：:Genomics projects have elucidated several genes that encode protein sequences. Subsequently, the advent of the proteomics age has enabled the synthesis and 3D structure determination for these protein sequences. Some of these proteins incorporate metal atoms but it is often not known whether they are metal-binding pro...

journal_title：Journal of inorganic biochemistry

authors： González-Díaz H,Sánchez-González A,González-Díaz Y

更新日期：2006-07-01 00:00:00

abstract：:This study performed in vitro and in vivo biological assays of the ruthenium (II) compound ct-[RuCl(CO)(dppb)(bipy)]PF6 (where, dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2'-bipyridine). The cytotoxic activity of this compound was evaluated against different tumor cell lines (HeLa, human cervical adenocarcinoma;...

journal_title：Journal of inorganic biochemistry

authors： Carnizello AP,Barbosa MI,Martins M,Ferreira NH,Oliveira PF,Magalhães GM,Batista AA,Tavares DC

更新日期：2016-11-01 00:00:00

abstract：:Herein we report the in-vivo characterisation and metabolic changes in Galleria mellonella larvae to a series of bis-chelate copper(II) phenanthroline-phenazine cationic complexes of [Cu(phen)2]2+ (Cu-Phen), [Cu(DPQ)(Phen)]2+ (Cu-DPQ-Phen) and [Cu(DPPZ)(Phen)]2+ (Cu-DPPZ-Phen) (where phen = 1,10-phenanthroline, DPQ = ...

journal_title：Journal of inorganic biochemistry

authors： Rochford G,Molphy Z,Browne N,Surlis C,Devereux M,McCann M,Kellett A,Howe O,Kavanagh K

更新日期：2018-09-01 00:00:00

abstract：:Quaternary systems of copper(II) complexes with adenosine 5'-triphosphate, O-phospho L-serine and with equimolar or excessive amount of spermine have been investigated. The studies have been performed in aqueous solution. Types of complexes and the overall stability constants have been determined using the potentiomet...

journal_title：Journal of inorganic biochemistry

authors： Jastrzab R,Runka T,Skowronek P,Lomozik L

更新日期：2010-08-01 00:00:00

abstract：:Oxyhemoglobin is oxidized to methemoglobin by copper(II) in a two-stage reaction that results in conversion of Fe(II) to Fe(III) in heme of the beta subunits, but not the alpha subunits. Glutathione and other thiols, which are slowly oxidized by Cu(II), protect oxyhemoglobin from Cu(II)-induced oxidation. In the prese...

journal_title：Journal of inorganic biochemistry

authors： Smith RC,Reed VD,Webb TR

更新日期：1993-11-15 00:00:00

abstract：:Horse spleen ferritin (HoSF) reconstituted with small iron cores ranging in size from 8 to 500 iron atoms was studied by magnetic susceptibility and pH measurements to determine when the added Fe3+ begins to aggregate and form antiferromagnetically coupled clusters and also to determine the hydrolytic state of the iro...

journal_title：Journal of inorganic biochemistry

authors： Hilty S,Webb B,Frankel RB,Watt GD

更新日期：1994-11-15 00:00:00

abstract：:Recent stopped-flow kinetics demonstrated the existence of an intermediate before the occurrence of the final product of the reaction of both iron-containing microperoxidase-8 (Fe(III)MP-8) and manganese-containing microperoxidase-8 (Mn(III)MP-8) with H(2)O(2). The intermediate was assigned to be (hydro)peroxo-iron. W...

journal_title：Journal of inorganic biochemistry

authors： Veeger C

更新日期：2002-07-25 00:00:00

abstract：:The new potential antitumour soluble drug K[Ru(eddp)Cl(2)].3H(2)O, (eddp=ethylenediamine-N,N'-di-3-propionate) has been isolated and characterized. The analysis of the interaction of this complex with pBR322 plasmid DNA by circular dichroism spectroscopy shows that the ruthenium complex initially induces alteration of...

journal_title：Journal of inorganic biochemistry

authors： Grguric-Sipka SR,Vilaplana RA,Pérez JM,Fuertes MA,Alonso C,Alvarez Y,Sabo TJ,González-Vílchez F

更新日期：2003-10-01 00:00:00

abstract：:Complex formation between Cu(II) and human and bovine beta-casomorphin heptapeptides, Tyr-Pro-Phe-Val-Glu-Pro-Ile and Tyr-Pro-Phe-Pro-Gly-Pro-Ile, respectively, was investigated by pH potentiometry and spectroscopic (CD, EPR and electronic absorption) techniques. The results showed the critical impact of Pro residues ...

journal_title：Journal of inorganic biochemistry

authors： Chruścińska E,Olczak J,Zabrocki J,Dyba M,Micera G,Sanna D,Kozłowski H

更新日期：1998-02-01 00:00:00

abstract：:The chemical structures of the pentavalent antimonial drugs, meglumine antimonate (MA) and sodium stibogluconate (SSG), were re-evaluated using electrospray ionization mass spectrometry (ESI-MS) and osmolarity measurements. Both MA and SSG were found to contain 1:1, 1:2, 2:2 and 2:3 Sb(V)-ligand complexes. ESI-MS anal...

journal_title：Journal of inorganic biochemistry

authors： Frézard F,Martins PS,Barbosa MC,Pimenta AM,Ferreira WA,de Melo JE,Mangrum JB,Demicheli C

更新日期：2008-04-01 00:00:00

abstract：:The proton equilibrium in aqueous surfactant solutions of hemin, (PPIX)Fe(H2O)+2, involving the propionic acid groups is reported (PPIX = protoporphyrinato IX). The surfactant used are sodium dodecyl sulphate (SDS), triton X-100 (TX-100) and hexadecyl trimethylammonium bromide (CTAB). The pKa values, determined spectr...

journal_title：Journal of inorganic biochemistry

authors： Das DK,Medhi OK

更新日期：1998-05-01 00:00:00

abstract：:Cystine, selenocytsine, and several analogs were reduced by dithiothreitol (DTT), beta-mercaptoethanol (ME) and sodium borohydride (NaBH4). DTT was the most effective; DTT to cystine ratios from 10 to 80 were equally effective. With selenocysteine, however, absorption was considerably reduced at all ratios. Selenocyst...

journal_title：Journal of inorganic biochemistry

authors： Burnell JN,Karle JA,Shrift A

更新日期：1980-07-01 00:00:00

abstract：:Palladium(II) complexes of 2-benzoylpyridine thiosemicarbazone (H2Bz4DH) and its N4-methyl (H2Bz4M) and N4-phenyl (H2Bz4Ph) derivatives were obtained and fully characterized. [Pd(2Bz4DH)Cl] (1) crystallizes in the monoclinic space group P21/c with a=11.671(1), b=10.405(1), c=13.124(1), beta=115.60(1) degrees and Z=4; ...

journal_title：Journal of inorganic biochemistry

authors： Rebolledo AP,Vieites M,Gambino D,Piro OE,Castellano EE,Zani CL,Souza-Fagundes EM,Teixeira LR,Batista AA,Beraldo H

更新日期：2005-03-01 00:00:00

abstract：:In 1991, treatment with low dose intramuscular desferrioxamine (DFO), a trivalent chelator that can remove excessive iron and/or aluminum from the body, was reported to slow the progression of Alzheimer's disease (AD) by a factor of two. Twenty years later this promising trial has not been followed up and why this tre...

journal_title：Journal of inorganic biochemistry

authors： Percy ME,Kruck TP,Pogue AI,Lukiw WJ

更新日期：2011-11-01 00:00:00

abstract：:The dinuclear complex [Zn(2)(DPCPMP)(pivalate)](ClO4), where DPCPMP is the new unsymmetrical ligand [2-(N-(3-((bis((pyridin-2-yl)methyl)amino)methyl)-2-hydroxy-5-methylbenzyl)-N-((pyridin-2-yl)methyl)amino)acetic acid], has been synthesized and characterized. The complex is a functional model for zinc phosphoesterases...

journal_title：Journal of inorganic biochemistry

authors： Das B,Daver H,Pyrkosz-Bulska M,Persch E,Barman SK,Mukherjee R,Gumienna-Kontecka E,Jarenmark M,Himo F,Nordlander E

更新日期：2014-03-01 00:00:00

abstract：:Gold(III) complexes bearing bidentate ligands based on the 1,10-phenanthroline and 2,2'-bipyridine scaffolds have shown promising anticancer activity against a variety of tumor cell lines. In particular, our laboratory has previously found that a pseudo five coordinate gold(III) complex possessing the 2,9-di-sec-butyl...

journal_title：Journal of inorganic biochemistry

authors： Olsen PM,Ruiz C,Lussier D,Le BK,Angel N,Smith M,Hwang CB,Khatib R,Jenkins J,Adams K,Getcher J,Tham F,Chen ZG,Wilson EH,Eichler JF

更新日期：2014-12-01 00:00:00

abstract：:The purpose of the present study was to evaluate the use of a non-innocent ligand as a surrogate of the anchored [4Fe4S] cubane in a synthetic mimic of the [FeFe] hydrogenase active site. Reaction of 2,3-bis(diphenylphosphino) maleic anhydride (bma) with [Fe(2)(CO)(6)(mu-pdt)] (propanedithiolate, pdt=S(CH(2))(3)S) in ...

journal_title：Journal of inorganic biochemistry

authors： Si Y,Charreteur K,Capon JF,Gloaguen F,Pétillon FY,Schollhammer P,Talarmin J

更新日期：2010-10-01 00:00:00

abstract：:Amino acid replacement is a useful strategy to assess the roles of axial heme ligands in the function of native heme proteins. THB1, the protein product of the Chlamydomonas reinhardtii THB1 gene, is a group 1 truncated hemoglobin that uses a lysine residue in the E helix (Lys53, at position E10 by reference to myoglo...

journal_title：Journal of inorganic biochemistry

authors： Nye DB,Johnson EA,Mai MH,Lecomte JTJ

更新日期：2019-12-01 00:00:00

abstract：:The experiments here reported evidence on the importance of the residual charge of a nucleotide derivative, for the adsorption on nHAP (hydroxyapatite nanocrystals), in water solution. We found that the simple presence of phosphates on the nucleotide derivative does not guarantee adsorption on nHAP. On the other hand,...

journal_title：Journal of inorganic biochemistry

authors： Benedetti M,Antonucci D,De Castro F,Girelli CR,Lelli M,Roveri N,Fanizzi FP

更新日期：2015-12-01 00:00:00