[Is streptococcal pharyngitis diagnosis possible?].

Abstract:

OBJECTIVE:To determine the validity of the Centor score (cervical adenopathy, tonsillar exudate, fever, and absence of catarrh symptoms) in diagnosing streptococcal pharyngitis (gold standard: throat swab). DESIGN:Descriptive study. SETTING:San Fernando 2 Health Centre, Madrid (outer urban area), Spain. PARTICIPANTS:On hundred forty patients over 14 years old who had a "sore throat" as main symptom and attended clinic between 14 February and 12 May, 2005. MAIN MEASUREMENTS:Sensitivity, specificity, positive and negative predictive values, and the probability quotients of the Centor score were determined. Pharyngeal throat culture was used as the reference method. RESULTS:Thirty four patients had positive throat culture (24.3%; 95% CI, 17.6%-32.4%). Finding the 4 criteria in the Centor score had a positive predictive value (PPV) of 48.1% (95% CI, 30.7%-66.0%) and a negative predictive value (NPV) of 81.4% (95% CI, 73.3%-87.5%); although only fever (OR, 3.64; 95% CI, 1.40-9.49) and tonsillar exudate (OR, 6.18; 95% CI, 2.08-18.35) were linked to streptococcal aetiology. CONCLUSIONS:The high NPV and specificity of the clinical score makes the diagnosis of non-streptococcal pharyngitis very accurate. However, the PPV is low: a high Centor score (3 or 4 criteria) does not mean streptococcal pharyngitis with certainty. What approach to take with patients suspected of streptococcal pharyngitis is not yet resolved (microbiological test, early antibiotic, or postponed antibiotic).

journal_name

Aten Primaria

journal_title

Atencion primaria

authors

Marín Cañada J,Cubillo Serna A,Gómez-Escalonilla Cruz N,Garzón de la Iglesia J,Benito Ortiz L,Reyes Fernández MN

doi

10.1157/13107724

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

361-5

issue

7

eissn

0212-6567

issn

1578-1275

pii

13107724

journal_volume

39

pub_type

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