Oral bisphosphonate associated osteonecrosis of the jaws: three case reports.

Abstract:

:Bisphosphonate associated osteonecrosis of the jaws (BONJ) has been well documented recently in relation to intravenous preparations of the drug. These are most commonly used as part of the management of hypercalcaemia of malignancy and metastatic bone disease but BONJ can also occur in association with oral bisphosphonate use. The oral preparations can also be prescribed in the management of metastatic bone disease but are more commonly used for the prevention and treatment of osteoporosis. Three case reports are presented in which alendronate, risedronate and ibandronate have been associated with osteonecrosis of the jaws. A review of the recent literature is used in the discussion of the management of these cases. The authors conclude, in agreement with other published authors, that prevention and early detection could be improved to reduce the occurrence and severity of this condition. However when BONJ is diagnosed, the early application of a closely monitored conservative regimen, with consideration given to discontinuation of the bisphosphonate, may give the best chance of containing or resolving the condition.

journal_name

Br Dent J

journal_title

British dental journal

authors

Malden NJ,Pai AY

doi

10.1038/bdj.2007.636

subject

Has Abstract

pub_date

2007-07-28 00:00:00

pages

93-7

issue

2

eissn

0007-0610

issn

1476-5373

pii

bdj.2007.636

journal_volume

203

pub_type

杂志文章
  • The cleaning of photographic retractors; a survey, clinical and laboratory study.

    abstract:OBJECTIVES:To determine the methods currently being used to decontaminate photographic retractors in specialist orthodontic practice and to investigate the effectiveness of the cleaning methods. DESIGN:The study was carried out in two parts: I - a postal self-report questionnaire, and II - a cross-sectional clinical a...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2010.310

    authors: Benson PE,Ebhohimen A,Douglas I

    更新日期:2010-04-10 00:00:00

  • Management of missing maxillary lateral incisors in general practice: space opening versus space closure.

    abstract::The aim of this paper is to inform the reader of the main principles considered in the management of mild hypodontia involving the absence of one or more maxillary lateral incisors. With increasing demand and limited resources of hospital dental services, general dental practitioners (GDPs) are required to actively pa...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/s41415-019-0082-4

    authors: Westgate E,Waring D,Malik O,Darcey J

    更新日期:2019-03-01 00:00:00

  • Infective endocarditis and the dental practitioner: a review of 53 cases involving litigation.

    abstract:OBJECTIVE:To review episodes of infective endocarditis involving dental procedures that have resulted in litigation and to determine if any clinical recommendations can be obtained. DESIGN:13-year retrospective study. INTERVENTION:Patient records were analysed to identify the probable cause of infective endocarditis....

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4809414

    authors: Martin MV,Butterworth ML,Longman LP

    更新日期:1997-06-28 00:00:00

  • An audit of study casts used to monitor tooth wear in general practice.

    abstract:OBJECTIVE:To assess the outcome of compliance of advice sent to patients and dentists about monitoring tooth wear in general practice. METHOD:Postal questionnaires were sent to 70 patients and their dentists requesting information on the outcome of letters of advice sent to general dental practitioners regarding monit...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4812570

    authors: Bartlett DW,Palmer I,Shah P

    更新日期:2005-08-13 00:00:00

  • Recognition of oral lesions of HIV infection. 1. Candidosis.

    abstract::Oral problems are often the first significant clinical manifestations of infection with human immunodeficiency virus (HIV). Their early recognition affords the best opportunity for effective therapeutic intervention of HIV infection and opportunistic infections, as well as for oral health education in order to avoid f...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4807360

    authors: Scully C,Epstein JB,Porter S,Luker J

    更新日期:1990-11-10 00:00:00

  • Patients' perceptions of the benefits of virtual reality during dental extractions.

    abstract::Objectives This study investigated patients' insights into whether virtual reality (VR) technology plays a beneficial role in reducing anxiety levels while undergoing dental extractions.Design Explorative study.Setting Oral Surgery Department of Birmingham Dental Hospital in July 2017.Material and methods Fifty patien...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/s41415-019-0939-6

    authors: Ougradar A,Ahmed B

    更新日期:2019-11-01 00:00:00

  • An exploratory study to investigate if patients are able to aid the early diagnosis of peri-implant complications.

    abstract:OBJECTIVES:This study investigated if the patient can have a role in reporting early peri-implant complications. DESIGN:An exploratory, single-centred study comparing patient's perceptions of implant success to the clinical success at an examination. SETTING, MATERIALS AND METHODS :Seventy-five patients were randomly ...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2015.503

    authors: Wright S,Archer C

    更新日期:2015-06-12 00:00:00

  • Fluoridation in Anglesey: a clinical study of dental caries in mothers at term.

    abstract::A study of dental caries was carried out involving 1537 mothers who attended St David's Hospital, Gwynedd, between July 1986 and July 1987 for their confinement. The study was 'blind' in respect of residence. The mean DMFT value for mothers with continuous residence in the non-fluoridated Gwynedd mainland was 13.6 and...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4807968

    authors: Thomas FD,Kassab JY

    更新日期:1992-09-05 00:00:00

  • Games in dental education: playing to learn or learning to play?

    abstract::Learners are motivated when using games and they have been successfully introduced in many healthcare subjects such as medicine and nursing. The development of games in dentistry has not kept pace with their uptake both as a popular pastime and their implementation in other subjects. Games in the learning space have m...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/s41415-019-0784-7

    authors: Pereira AC,Walmsley AD

    更新日期:2019-09-01 00:00:00

  • Teaching periodontal pocket charting to dental students: a comparison of computer assisted learning and traditional tutorials.

    abstract:AIM:The aim of this study was to compare the effectiveness of a computer assisted learning (CAL) programme with that of traditional small group tutorials in teaching theoretical and practical aspects of periodontal pocket charting. METHOD:Sixty-one third year undergraduate dental students were randomized to either rec...

    journal_title:British dental journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1038/sj.bdj.4810535

    authors: Bissell V,McKerlie RA,Kinane DF,McHugh S

    更新日期:2003-09-27 00:00:00

  • A study of the quality of impressions for anterior crowns received at a commercial laboratory.

    abstract::A report is presented of a study which was carried out to investigate the standard of impressions for anterior crowns received at a commercial dental laboratory in Great Britain. Aspects examined were the type of tray and its suitability to the impression technique used, fixation of the impression to the tray, the met...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4808129

    authors: Carrotte PV,Winstanley RB,Green JR

    更新日期:1993-04-10 00:00:00

  • Summary of: job satisfaction among dually qualified dental hygienist-therapists in UK primary care: a structural model.

    abstract:OBJECTIVE:To investigate job satisfaction among hygienist-therapists. Increasing numbers of hygienist-therapists work in UK primary dental care teams. Earlier studies suggest a clinical remit/clinical activity mismatch, without investigating any link with job satisfaction. METHODS:A UK-wide survey of dental hygienist-...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2011.116

    authors: Csikar J,Godson J

    更新日期:2011-02-26 00:00:00

  • Investigation of inhalational conscious sedation as a tool for reducing anxiety in adults undergoing exodontia.

    abstract:AIM:To determine whether adult patients' dental anxiety levels decrease following exodontia carried out under inhalational conscious sedation with nitrous oxide and oxygen (IHS) and local anaesthetic (LA). DESIGN:Retrospective analysis of pre- and post-operative modified dental anxiety score (MDAS) questionnaires comp...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2012.839

    authors: Hierons RJ,Dorman ML,Wilson K,Averley P,Girdler N

    更新日期:2012-09-01 00:00:00

  • Subdural empyema resulting from displacement of a root into the maxillary antrum.

    abstract::Subdural empyema is a rare but serious complication of paranasal sinusitis which may result in death or permanent disability in a significant proportion of cases. A case is presented in which displacement of a premolar root in the maxillary sinus led to a subdural empyema and a resultant left-sided hemiplegia. This ca...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4809404

    authors: Woolley EJ,Patel M

    更新日期:1997-06-14 00:00:00

  • Chemochemical caries removal: a review of the techniques and latest developments.

    abstract::Chemomechanical caries removal involves the chemical softening of carious dentine followed by its removal by gentle excavation. The reagent involved is generated by mixing amino acids with sodium hypochlorite; N-monochloroamino acids are formed which selectively degrade demineralised collagen in carious dentine. The p...

    journal_title:British dental journal

    pub_type: 杂志文章,评审

    doi:10.1038/sj.bdj.4800501

    authors: Beeley JA,Yip HK,Stevenson AG

    更新日期:2000-04-22 00:00:00

  • The frequency of dental attendance of Scottish dentate adults between 1978 and 1988.

    abstract::The dental attendance of a sample of dentate adults (n = 702) within the National Health Service in Scotland was monitored longitudinally between 1978 and 1988. The attendance pattern of the sample appeared to be no different between 1983-88 than in the preceding 5 years, which suggests that the attendance behaviour o...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4807646

    authors: Nuttall NM,Davies JA

    更新日期:1991-09-21 00:00:00

  • Radiation doses of indirect and direct digital cephalometric radiography.

    abstract:AIM:The aim of this study was to measure organ doses and calculate the effective dose for indirect and direct digital cephalometric exposures. MATERIAL AND METHODS:Indirect digital cephalometric exposures were made of a Rando phantom head using a Cranex Tome multipurpose unit with storage phosphor plates from Agfa and...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4811532

    authors: Gijbels F,Sanderink G,Wyatt J,Van Dam J,Nowak B,Jacobs R

    更新日期:2004-08-14 00:00:00

  • Sugar consumption and dental caries: evidence from 90 countries.

    abstract::An examination is made of data on dental caries amongst 12-year-old children and sugar consumption of the total population for 90 countries. For the whole data set, DMFT score tends to rise with sugar consumption. The linear relationship between the logarithm of DMFT and sugar is estimated to have a slope of 0.021 per...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4808437

    authors: Woodward M,Walker AR

    更新日期:1994-04-23 00:00:00

  • Survey of UK dentists regarding the use of CAD/CAM technology.

    abstract::Statement of the problem Digital workflows (CAD/CAM) have been introduced in dentistry during recent years. No published information exists on dentists' use and reporting of this technology.Purpose The purpose of this survey was to identify the infiltration of CAD/CAM technology in UK dental practices and to investiga...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2016.862

    authors: Tran D,Nesbit M,Petridis H

    更新日期:2016-11-18 00:00:00

  • Periodontal diagnosis in the context of the BSP implementation plan for the 2017 classification system of periodontal diseases and conditions: presentation of a pair of young siblings with periodontitis.

    abstract::The objective of this case report is to illustrate the diagnosis and classification of periodontitis according to the 2017 classification system as recommended in the British Society of Periodontology (BSP) implementation plan. We describe two cases in the form of a pair of siblings, who developed periodontitis very e...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2019.2

    authors: Walter C,Chapple ILC,Ower P,Tank M,West NX,Needleman I,Hughes FJ,Wadia R,Milward MR,Hodge PJ,Dietrich T,British Society of Periodontology.

    更新日期:2019-01-11 00:00:00

  • Tackling a bus with a toothbrush.

    abstract::'Been there...done that...now what?' Is this what can be said of all dentists following Vocational Training? In fact, it is the title of a booklet given to all Ventures following an expedition with Operation Raleigh. ...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4807017

    authors: Murphy S

    更新日期:1989-11-11 00:00:00

  • Educational aspects of oral cancer.

    abstract::The incidence of oral and oropharyngeal cancer is rising in the UK, its aetiology is changing and early detection and referral saves lives. This article covers how and to what depth oral and oropharyngeal cancer is taught to dental students and other preregistration dental care professionals and examines the threats i...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2018.925

    authors: Farthing PM,Speight PM

    更新日期:2018-11-09 00:00:00

  • A clinical evaluation of all-ceramic bridges placed in UK general dental practices: first-year results.

    abstract:PURPOSE:To report the results at year one of a three-year evaluation of the performance of fixed all-ceramic bridges, constructed with a yttrium tetragonal zirconia polycrystal substructure placed in adult patients in UK general dental practices and cemented using a self-adhesive resin-based cement. METHODS:Ethical ap...

    journal_title:British dental journal

    pub_type: 杂志文章,多中心研究

    doi:10.1038/sj.bdj.2008.937

    authors: Crisp RJ,Cowan AJ,Lamb J,Thompson O,Tulloch N,Burke FJ

    更新日期:2008-11-08 00:00:00

  • Patient decision-making in relation to extensive restorative dental treatment. Part II: Evaluation of a patient decision-making model.

    abstract::A theoretical model was proposed and tested to evaluate some of the factors involved in patients' decisions to undergo extensive restorative dental treatment. This model incorporates aspects of the environment within which the decision occurred (the patient/provider relationship, social influence and the role of cues ...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4808807

    authors: Oates AJ,Fitzgerald M,Alexander G

    更新日期:1995-07-08 00:00:00

  • Using a situational judgement test for selection into dental core training: a preliminary analysis.

    abstract::Objective and setting This paper describes the evaluation of a pilot situational judgement test (SJT) for selection into UK Dental Core Training (DCT). The SJT's psychometric properties, group differences based on gender and ethnicity, and candidate reactions were assessed.Methods The SJT targets four non-academic att...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2017.410

    authors: Rowett E,Patterson F,Cousans F,Elley K

    更新日期:2017-05-12 00:00:00

  • Antibiotic prophylaxis for implant placement: a systematic review of effects on reduction of implant failure.

    abstract::Introduction Despite excellent reviews in the past several years, the use of antibiotics as prophylaxis for implant placement remains controversial.Aim To assess the literature on the efficacy of prophylactic antibiotics prescribed prior to and immediately following implant surgery (PIFS).Outcomes Whether administrati...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/s41415-020-1649-9

    authors: Kim AS,Abdelhay N,Levin L,Walters JD,Gibson MP

    更新日期:2020-06-01 00:00:00

  • Quality control in orthodontics: factors influencing the receipt of orthodontic treatment.

    abstract::The factors which influence the uptake of orthodontic treatment are reviewed with respect to the features and aspirations of the consumers (patients and parents) and the providers (dentists, orthodontists and health system). It appears that the assessment of orthodontic treatment need is influenced by many variables r...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.4807421

    authors: Shaw WC,O'Brien KD,Richmond S

    更新日期:1991-01-19 00:00:00

  • Oral healthcare management in heroin and methadone users.

    abstract::Heroin addiction is associated with poor oral health. Oral and dental care in heroin addiction might be complicated by altered mental status, negative attitude towards oral health, dental anxiety and fear, drug interaction, and associated medical co-morbidity. We present the oral findings and discuss the dental, behav...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/s41415-019-0206-x

    authors: Abed H,Hassona Y

    更新日期:2019-04-01 00:00:00

  • The effects of NICE guidelines on the management of third molar teeth.

    abstract:BACKGROUND:Third molar surgery (TMS) is probably one of the most commonly performed surgical procedures undertaken in the NHS. In 2000, the National Institute of Clinical Excellence (NICE) introduced guidelines relating to TMS. These recommended against the prophylactic removal of third molars and listed specific clini...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/sj.bdj.2012.780

    authors: McArdle LW,Renton T

    更新日期:2012-09-01 00:00:00

  • Access to dental services in Scotland: an analysis of dentist-population ratios.

    abstract:OBJECTIVE:To assess inequalities in the availability of NHS dental services between Health Boards in Scotland. STUDY DESIGN:Postal questionnaire survey of all dentists (n = 2,852) registered with the General Dental Council at an address in Scotland. METHODS:Data obtained on NHS working hours were used to model dentis...

    journal_title:British dental journal

    pub_type: 杂志文章

    doi:10.1038/bdj.2007.1107

    authors: Newton JT,Williams AC,Bower EJ

    更新日期:2008-02-09 00:00:00