Framework for intake simulation of functional ingredients.

Abstract:

OBJECTIVE:To create a general framework for the simulation of intakes from mandatory or voluntary fortification, which will make outcomes of simulation studies more comparable and give insight on uncertainties. DESIGN:A general framework was developed based on methods used in already published case studies of mandatory fortification. The framework was extended to be suitable for the simulation of voluntary fortification. Case studies of folic acid fortification were used to illustrate the general framework. RESULTS:The developed framework consists of six steps. First, the definition of the fortification strategy (step 1), followed by the identification of potential carrier products (step 2), and the definition of fortification levels or ranges (step 3). Thereafter, virtual food/supplement composition data are created (step 4) and food/supplement consumption data are required (step 5). Finally, the intake of the functional ingredient from functional foods, other foods and dietary supplements is calculated during the simulation resulting in total habitual intake distributions (step 6). CONCLUSIONS:Simulation of both mandatory and voluntary folic acid fortification in The Netherlands showed that the general framework is applicable. Also with incomplete data or data from different sources, the (habitual) intake distributions can be estimated using assumptions, statistical procedures or probabilistic modelling approaches. It is important that the simulation procedure is described well, so that an insight on uncertainties and knowledge gaps to be filled is given.

journal_name

Public Health Nutr

journal_title

Public health nutrition

authors

Kloosterman J,Bakker MI,de Jong N,Ocké MC

doi

10.1017/S1368980007000316

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

279-87

issue

3

eissn

1368-9800

issn

1475-2727

pii

S1368980007000316

journal_volume

11

pub_type

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