Development and Validation of an Improved, COPD-Specific Version of the St. George Respiratory Questionnaire.

abstract：BACKGROUND:Emphysema is the only smoking-related disease in which white patients have higher prevalence and higher attributable mortality rates than African-American patients. Epidemiologic studies have not addressed, nor explained, the observed racial differences in emphysema. STUDY OBJECTIVES:To determine whether wh...

journal_title：Chest

authors： Chatila WM,Hoffman EA,Gaughan J,Robinswood GB,Criner GJ,National Emphysema Treatment Trial Research Group.

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:N-terminal pro-brain natriuretic peptide (NT-proBNP) is a byproduct of the brain natriuretic peptide (BNP) that was shown to be of prognostic value in pulmonary hypertension (PH). The role of NT-proBNP in PH has to be determined, especially under the influence of renal impairment that might lead to an accumu...

journal_title：Chest

authors： Leuchte HH,El Nounou M,Tuerpe JC,Hartmann B,Baumgartner RA,Vogeser M,Muehling O,Behr J

更新日期：2007-02-01 00:00:00

abstract：:There is renewed interest in the classification and methods of recording adventitious pulmonary sounds. This is a study of the importance of fine crackles (rales) in the diagnosis and estimation of the severity of diffuse infiltrative pulmonary disease. Among 272 cases documented by lung biopsy, bilateral fine crackle...

journal_title：Chest

authors： Epler GR,Carrington CB,Gaensler EA

更新日期：1978-03-01 00:00:00

abstract：:Data on pulmonary function, with particular reference to flow-volumes, were obtained in 760 normal healthy Indians in Bombay, who had never smoked and who had no symptom or history of cardiorespiratory disease. Prediction equations were derived for spirometric parameters and for maximal expiratory flows. The maximal e...

journal_title：Chest

authors： Udwadia FE,Sunavala JD,Shetye VM,Jain PK

更新日期：1986-06-01 00:00:00

abstract：:COPD and OSA are both highly prevalent, which implies that both disorders occurring together (overlap syndrome) is likely to be common based on chance association alone. However, different clinical COPD phenotypes influence the likelihood of coexisting OSA in that the increased lung volumes and low BMI associated with...

journal_title：Chest

authors： McNicholas WT

更新日期：2017-12-01 00:00:00

abstract：:The call for meaningful patient and family engagement in research has recently gained considerable momentum. This article defines patient and family engagement broadly and specifically in clinical research. Using a multicenter, North American weaning trial as an exemplar, we describe our early experiences as clinical ...

journal_title：Chest

authors： Burns KEA,Devlin JW,Hill NS

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Linear endobronchial ultrasound (EBUS) allows real-time guidance of transbronchial needle aspiration of thoracic structures and has become an increasingly important diagnostic tool for chest physicians. Little has been published about the learning experience of operators with this technology. The purpose of ...

journal_title：Chest

authors： Wahidi MM,Hulett C,Pastis N,Shepherd RW,Shofer SL,Mahmood K,Lee H,Malhotra R,Moser B,Silvestri GA

更新日期：2014-03-01 00:00:00

abstract：:The effects of erythromycin on the NADPH oxidase activity in the neutrophils of normal subjects and patients with bronchiolitis were investigated. In the patients receiving erythromycin, NADPH oxidase activity was significantly lower in a whole-cell system than that before therapy. Erythromycin was also found to inhib...

journal_title：Chest

authors： Umeki S

更新日期：1993-10-01 00:00:00

abstract：:Recent studies have suggested that vasodilators may acutely improve pulmonary hemodynamics in patients with chronic obstructive pulmonary disease and cor pulmonale, but the effects of long-term therapy have not been assessed. We evaluated the hemodynamic and gas exchange effects of nitrendipine, a calcium channel bloc...

journal_title：Chest

authors： Rubin LJ,Moser K

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence of work disability among adults with asthma and to evaluate a clinically based illness severity score as a predictor of such disability. DESIGN:Baseline and follow-up telephone interviews and medical record review. SETTING:University-based outpatient pulmonary specialty practice. ...

journal_title：Chest

authors： Blanc PD,Jones M,Besson C,Katz P,Yelin E

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Signs of both motor and sensory nervous lesions have previously been shown in the upper airway of patients with OSA and habitual snorers. Snoring per se may damage all upper airway neurons over time, thereby causing progression to manifest sleep apnea. To test this hypothesis, nonsnoring subjects, untreated ...

journal_title：Chest

authors： Svanborg E,Ulander M,Broström A,Sunnergren O

更新日期：2020-05-01 00:00:00

abstract：:Previous studies on the bronchodilating effect of nitrates yielded conflicting results. We hypothesized that the concomitant bronchial vasodilatation induced by nitrates may limit the increase of airway patency due to bronchial smooth muscle relaxation. To test this hypothesis, we evaluated the bronchodilating effect ...

journal_title：Chest

authors： Rolla G,Bucca C,Brussino L

更新日期：1995-01-01 00:00:00

abstract：:It has been suggested that fiberoptic bronchoscopy may induce life-threatening bronchospasm in persons with asthma. The safety of bronchoscopy and bronchoalveolar lavage (BAL) with bilateral installation of 300 ml of saline solution was assessed prospectively in ten adults with mild asthma as a part of a study of the ...

journal_title：Chest

authors： Rankin JA,Snyder PE,Schachter EN,Matthay RA

更新日期：1984-06-01 00:00:00

abstract：:It is estimated that 350,000 people suffer a cardiac arrest each year in the United States, with one-half occurring out-of-hospital and the other half in-hospital. Overall survival is < 10% and has not changed significantly for decades. CPR is the umbrella term for attempts to restore organized cardiac contractility a...

journal_title：Chest

authors： Gaieski DF,Abella BS,Goyal M

更新日期：2012-04-01 00:00:00

abstract：:Dyspnea after polio can occur for a variety of reasons, including neuromuscular disease and upper airway abnormalities resulting from prolonged intubation, including tracheal stenosis, tracheomalacia, and vocal cord paralysis. Routine studies such as spirometry and maximum voluntary ventilation (MVV) measurements can ...

journal_title：Chest

authors： Knobil K,Becker FS,Harper P,Graf LB,Wolf GT,Martinez FJ

更新日期：1994-03-01 00:00:00

abstract：:Twenty-one patients with malignant pleural effusion (MPE) were prospectively entered into a nonrandomized, single-armed study to evaluate the efficacy and safety of recombinant interferon (IFN) alpha-2b (INTRON A; Schering-Plough; Kenilworth, NJ) as an intrapleural palliative agent. From March 1989 through February 19...

journal_title：Chest

authors： Wilkins HE 3rd,Connolly MM,Grays P,Marquez G,Nelson D

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...

journal_title：Chest

authors： Himes BE,Klanderman B,Ziniti J,Senter-Sylvia J,Soto-Quiros ME,Avila L,Celedón JC,Lange C,Mariani TJ,Lasky-Su J,Hersh CP,Raby BA,Silverman EK,Weiss ST,DeMeo DL

更新日期：2011-09-01 00:00:00

abstract：:Uterine life is arguably the most critical time in developmental programming, when environmental exposures may have the greatest potential to influence evolving fetal structure and function. There has been substantial progress in understanding the epigenetic mechanisms through which environmental exposures can permane...

journal_title：Chest

authors： Martino D,Prescott S

更新日期：2011-03-01 00:00:00

abstract：STUDY OBJECTIVES:Precise epidemiologic data regarding nontuberculous mycobacterial (NTM) lung infection in many Asian countries have been relatively unavailable. In order to determine the clinical significance of NTM isolated from respiratory specimens, we reviewed medical records from all patients from whom NTM isolat...

journal_title：Chest

authors： Koh WJ,Kwon OJ,Jeon K,Kim TS,Lee KS,Park YK,Bai GH

更新日期：2006-02-01 00:00:00

abstract：:The previously unreported association of chronic persistent cough due to a duplication esophageal cyst is presented. The presence of a long history of atopy, bronchitis, and asthma resulted in a delay in diagnosis. When vigorous bronchodilator therapy was unsuccessful, close observation of the patient and review of he...

journal_title：Chest

authors： Bowton DL,Katz PO

更新日期：1984-07-01 00:00:00

abstract：:Asthma and COPD are common respiratory diseases that are caused by the interaction of genetic susceptibility with environmental factors. Environmental influences are important in both diseases, and although there are differences in genetic susceptibilities, there are also similarities. Three examples of interest for b...

journal_title：Chest

authors： Meyers DA,Larj MJ,Lange L

更新日期：2004-08-01 00:00:00

abstract：STUDY DESIGN:We tested the hypothesis that maximal exercise performance in subjects with interstitial lung disease (ILD) is limited by respiratory factors. Assuming this is so, ventilatory stimulation by added dead space (VD) should impair exercise capacity. METHODS:Six subjects with ILD each underwent three maximal i...

journal_title：Chest

authors： Marciniuk DD,Watts RE,Gallagher CG

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Data on patients with cancer who have a prolonged length of stay (LOS) in the ICU are scarce. The aim of the present study was to evaluate the characteristics and the outcomes of cancer patients with life-threatening complications with an ICU stay > or = 21 days. METHODS:A cohort study performed at a 10-bed...

journal_title：Chest

authors： Soares M,Salluh JIF,Torres VBL,Leal JVR,Spector N

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Mycobacterium kansasii infection is one of the most common causes of nontuberculous mycobacterial lung disease in world. However, little is known about its background characteristics or drug sensitivity in nonendemic areas. DESIGN:We assessed the clinical features, radiologic findings, and drug sensitivity ...

journal_title：Chest

authors： Shitrit D,Baum GL,Priess R,Lavy A,Shitrit AB,Raz M,Shlomi D,Daniele B,Kramer MR

更新日期：2006-03-01 00:00:00

abstract：INTRODUCTION:Gastroesophageal reflux has been suggested as an underlying cause of chronic lung disease. The aim of this study was to assess the value of pepsin and bile acids, both components of GI secretions, in the lungs of children with chronic lung diseases as possible markers for gastroesophageal reflux disease an...

journal_title：Chest

authors： Starosta V,Kitz R,Hartl D,Marcos V,Reinhardt D,Griese M

更新日期：2007-11-01 00:00:00

abstract：:Bronchoalveolar lavage (BAL) has not been associated with the complication of pneumothorax. Candidates for this procedure are predisposed to develop pneumothorax due to underlying infectious interstitial emphysema. This risk factor is increased by the hyperbaric consequences of lavage and also by the cough induced by ...

journal_title：Chest

authors： Krueger JJ,Sayre VA,Karetzky MS

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:The Centers for Medicare and Medicaid Services stipulate shared decision-making (SDM) counseling as a prerequisite to lung cancer screening (LCS) reimbursement, despite well-known challenges implementing SDM in practice. RESEARCH QUESTION:How have health-care organizations implemented SDM for LCS? STUDY DE...

journal_title：Chest

authors： Alishahi Tabriz A,Neslund-Dudas C,Turner K,Rivera MP,Reuland DS,Elston Lafata J

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The practice of treating a solitary pulmonary nodule (SPN) suspicious for stage I non-small cell lung cancer (NSCLC) with stereotactic ablative radiotherapy (SABR) in the absence of pathology is growing. In the absence of randomized evidence, the appropriate prior probability threshold of lung cancer of when...

journal_title：Chest

authors： Louie AV,Senan S,Patel P,Ferket BS,Lagerwaard FJ,Rodrigues GB,Salama JK,Kelsey C,Palma DA,Hunink MG

更新日期：2014-10-01 00:00:00

abstract：:A growing number of drugs, including a number of alkylating agents, have been implicated as the cause of pulmonary diseases. A patient with chronic myelogenous leukemia presented with typical cytology, biopsy, and roentgenologic findings of lung toxicity after only six weeks of therapy with busulfan. There was subsequ...

journal_title：Chest

authors： Hankins DG,Sanders S,MacDonald FM,Drage CW

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Self-efficacy explores the emotional functioning and coping skills of an individual and is thought to be a strong predictor of health behaviors, which is particularly important for pulmonary rehabilitation (PR). However, to our knowledge, there is no measure of self-efficacy developed to explore behavior cha...

journal_title：Chest

authors： Vincent E,Sewell L,Wagg K,Deacon S,Williams J,Singh S

更新日期：2011-12-01 00:00:00