Bronchoalveolar pepsin, bile acids, oxidation, and inflammation in children with gastroesophageal reflux disease.

abstract：:We characterized the bronchopulmonary distribution of a 0.9 percent saline aerosol (1.12 microM) labelled with 99mTc sulfur colloid in nine normal subjects and five patients with CF. Homogeneity of distribution was quantified using indices derived from computerized analysis of Anger camera pulmonary images including s...

journal_title：Chest

authors： Laube BL,Links JM,LaFrance ND,Wagner HN Jr,Rosenstein BJ

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:There are several reports on underdiagnosis of COPD, while little is known about COPD overdiagnosis and overtreatment. We describe the overdiagnosis and the prevalence of spirometrically defined false positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries...

journal_title：Chest

authors： Sator L,Horner A,Studnicka M,Lamprecht B,Kaiser B,McBurnie MA,Buist AS,Gnatiuc L,Mannino DM,Janson C,Bateman ED,Burney P,BOLD Collaborative Research Group.

更新日期：2019-08-01 00:00:00

abstract：STUDY OBJECTIVES:Gastroesophageal reflux disease (GERD) and asthma are common causes for consultation in primary care, but the relationship between the two remains unclear. The aim of our study was to investigate the temporal relationship between first diagnoses of GERD and asthma in general practice. METHODS:We used ...

journal_title：Chest

authors： Ruigómez A,Rodríguez LA,Wallander MA,Johansson S,Thomas M,Price D

更新日期：2005-07-01 00:00:00

abstract：:The weak relationship between left ventricular function and exercise capacity in heart failure has stimulated interest in neurohumoral mechanisms as possibly contributing to exercise intolerance. Although chronic activation of neuroendocrine systems is characteristic of heart failure and is accompanied by impaired ref...

journal_title：Chest

authors： Cohn JN

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The use of both heroin and cocaine has been associated with asthma exacerbations. However, the magnitude of this effect has not been adequately described. The purpose of this study was to examine the association between cocaine or heroin use and asthma severity. METHODS:We conducted a retrospective chart re...

journal_title：Chest

authors： Levine M,Iliescu ME,Margellos-Anast H,Estarziau M,Ansell DA

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Portable monitoring is a convenient means for diagnosing sleep apnea. However, data on whether one night of monitoring is sufficiently precise for the diagnosis of sleep apnea are limited. RESEARCH QUESTION:The current study sought to determine the variability and misclassification in disease severity over ...

journal_title：Chest

authors： Punjabi NM,Patil S,Crainiceanu C,Aurora RN

更新日期：2020-07-01 00:00:00

abstract：STUDY OBJECTIVE:To compare drug output from a vented nebulizer (Pari LC Jet Plus) with a traditional unvented nebulizer (Hudson 1730 T Up-Draft 11) using aerosolized tobramycin, which is frequently used in the treatment of cystic fibrosis. DESIGN:Six nebulizers of each type were filled with a 4 mL tobramycin (80 mg) s...

journal_title：Chest

authors： Coates AL,MacNeish CF,Lands LC,Meisner D,Kelemen S,Vadas EB

更新日期：1998-04-01 00:00:00

abstract：:Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese...

journal_title：Chest

authors： Greenberger JS,Bahri S,Jett J,Belani C,Kalend A,Epperly M

更新日期：1998-01-01 00:00:00

abstract：:The factors that influence decision making among surgeons are not well understood. We evaluated how tumor stage in patients subjected to potentially curative surgery for lung cancer affects the self-reported follow-up strategies employed by practicing surgeons. Hypothetical patient profiles and a detailed questionnair...

journal_title：Chest

authors： Johnson FE,Naunheim KS,Coplin MA,Virgo KS

更新日期：1997-01-01 00:00:00

abstract：:A newborn infant with severe respiratory distress from bilateral diaphragmatic paralysis caused by birth injury was successfully treated with nasal continuous positive airway pressure (CPAP). Improvement gradually occurred, and CPAP was discontinued after he was 23 days of age. This therapy has advantages over alterna...

journal_title：Chest

authors： Zajkowski EJ,Kravath RE

更新日期：1979-03-01 00:00:00

abstract：:Fiberglass inhalation seems to produce a minimal tissue response in the lungs, and the reaction is one of macrophagic mobilization and is characteristic of the pulmonary response to those nonfibrogenic dusts classified as nuisance dusts. In order to merit the designation of a nuisance dust, the pulmonary response must...

journal_title：Chest

authors：

更新日期：1976-02-01 00:00:00

abstract：:Numerous clinical trials of chemotherapy for tuberculosis conducted throughout the world over the past 4 decades have established 2 basic principles of treatment: effective treatment requires the initial concomitant administration of at least 2 drugs to which the patient's organisms are susceptible; and cure of tuber...

journal_title：Chest

authors： Snider DE Jr,Cohn DL,Davidson PT,Hershfield ES,Smith MH,Sutton FD Jr

更新日期：1985-02-01 00:00:00

abstract：:It is known that smoking affects the development and maintenance of certain types of granulomatous lung diseases. To explore this mechanism(s), we measured tumor necrosis factor (TNF)-alpha concentrations in the culture supernatants of lipopolysaccharide (LPS)-stimulated alveolar macrophages (AMs) in 13 healthy nonsmo...

journal_title：Chest

authors： Yamaguchi E,Itoh A,Furuya K,Miyamoto H,Abe S,Kawakami Y

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The prevalence of COPD is estimated to 4 to 14%. According to the Global Initiative for Chronic Obstructive Lung Disease guidelines, COPD is divided into four stages. Patients with stage IV disease (very severe) have FEV1 < 30% of predicted values and/or respiratory insufficiency. The few studies that exist ...

journal_title：Chest

authors： Stenfors N

更新日期：2006-09-01 00:00:00

abstract：:A 32-year-old woman with a one-year history of progressive shortness of breath and chest pain was found to have a grade 4/6 systolic murmur at the base of the heart and left sternal border. Right ventricular enlargement was found by physical examination, ECG, and chest roentgenogram. Cardiac catheterization showed ele...

journal_title：Chest

authors： Betancourt B,Defendini EA,Johnson C,De Jesús M,Pavía-Villamil A,Díaz Cruz A,Medina JC

更新日期：1979-04-01 00:00:00

abstract：STUDY OBJECTIVES:To evaluate the efficacy of mass spirometry use for the detection of airflow obstruction in a high-risk population. DESIGN:Free spirometry was offered to smokers who were > 39 years of age with a smoking history of > 10 pack-years. Action was preceded by the dissemination of information on the causes ...

journal_title：Chest

authors： Zieliñski J,Bednarek M,Know the Age of Your Lung Study Group.

更新日期：2001-03-01 00:00:00

abstract：STUDY OBJECTIVES:Among adults presenting to the emergency department (ED) with acute asthma, we sought to determine the prevalence of obesity, and the relation of body mass index (BMI) to asthma severity in this high-risk population. DESIGN:Multicenter, prospective cohort study. SETTING:Twenty-six North American EDs....

journal_title：Chest

authors： Thomson CC,Clark S,Camargo CA Jr,MARC Investigators.

更新日期：2003-09-01 00:00:00

abstract：:A series of 24 adult male patients undergoing thoracotomy were found to have a reduction in their cough pressures in the immediate postoperative period to 29 percent of their preoperative values. Cough pressures still averaged only 50 percent of control values one week following surgery, with slow return toward normal...

journal_title：Chest

authors： Byrd RB,Burns JR

更新日期：1975-06-01 00:00:00

abstract：:A case of acute pneumonia due to Pasteurella multocida ssp multocida occurred in a young man with AIDS and chronic sinusitis. The pneumonia was diagnosed by bronchoscopy and responded to treatment with aztreonam. Epidemiologic investigation revealed the case was temporally related to nontraumatic exposure to cat secre...

journal_title：Chest

authors： Drabick JJ,Gasser RA Jr,Saunders NB,Hadfield TL,Rogers LC,Berg BW,Drabick CJ

更新日期：1993-01-01 00:00:00

abstract：STUDY OBJECTIVES:Autopsy evaluation of tracheobronchomalacia (TBM) in patients with Duchenne muscular dystrophy (DMD) who were receiving long-term ventilation through uncuffed tracheostomies. DESIGN:Necropsies were performed in seven patients with DMD who had received positive-pressure ventilation through uncuffed tra...

journal_title：Chest

authors： Baydur A,Kanel G

更新日期：2003-04-01 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the cost effectiveness of the Nd-YAG laser and bronchoscopic electrocautery for palliation in patients with symptomatic tumor obstruction. DESIGN:A retrospective study. SETTING:Bronchoscopy unit of a university hospital. PATIENTS AND INTERVENTION:Thirty-one consecutive patients with inope...

journal_title：Chest

authors： Boxem Tv,Muller M,Venmans B,Postmus P,Sutedja T

更新日期：1999-10-01 00:00:00

abstract：:A case of disseminated histoplasmosis followed later by disseminated coccidioidomycosis is described. The clinical illness and immunologic studies suggest subtle defects that may have existed antecedent to infection and, thus, provided an opportunity for widespread dissemination by these normally nonopportunistic orga...

journal_title：Chest

authors： Kaplan P,Graybill JR,Thor D

更新日期：1977-08-01 00:00:00

abstract：CASE PRESENTATION:A 72-year-old man underwent endoscopic resection of a 10-mm polypoid sessile lesion of the rectum. Histologic examination found a well-differentiated, low-grade (G1), neuroendocrine tumor. A thoracoabdominal CT scan was performed for staging purposes. The chest CT scan revealed a so-called cannonball-...

journal_title：Chest

authors： Scamporlino A,Mengoli MC,Calabrese O,Della Casa G,Aramini B,Spallanzani A,Morandi U,Stefani A

更新日期：2019-10-01 00:00:00

abstract：STUDY OBJECTIVES:To ascertain whether inspiratory pressure support (IPS) can be triggered reliably from and targeted at esophageal pressures (Pes), and to compare the work of breathing and time delay to initiation of inspiratory flow between conventional pressure support and esophageal-directed pressure support (EDPS)....

journal_title：Chest

authors： Barnard M,Shukla A,Lovell T,Goldstone J

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The synthetic peptide solnatide is a novel pharmacologic agent that reduces extravascular lung water, blunts reactive oxygen species production, and improves lung function due to its ability to directly activate the epithelial sodium channel. The goal of this study was to investigate the effect of solnatide ...

journal_title：Chest

authors： Zhou Q,Wang D,Liu Y,Yang X,Lucas R,Fischer B

更新日期：2017-03-01 00:00:00

abstract：:Ozone can cause pulmonary edema and simultaneously decrease blood pressure. Atrial natriuretic factor (ANF) may mediate both of these effects in that it increases pulmonary capillary permeability resulting in edema formation and vasodilates the vascular system. The present investigation was designed to test directly t...

journal_title：Chest

authors： Vesely DL,Giordano AT,Raska-Emery P,Montgomery MR

更新日期：1994-05-01 00:00:00

abstract：:Three patients under two years of age are described with unusual fistulas involving the brachiocephalic arteries and the innominate vein or the superior vena cava. Two patients were asymptomatic, and one newborn was cyanotic and in congestive failure. This unusual presentation has only rarely been reported in thoracic...

journal_title：Chest

authors： Gutierrez FR,Monaco MP,Hartmann AF Jr,McKnight RC

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:Patients with COPD are at risk for cardiovascular events. This is attributed to increased systemic inflammation. The course of COPD is punctuated by exacerbations, which further increase systemic inflammation, but the risk of vascular events in the postexacerbation period has never been defined. METHODS:We a...

journal_title：Chest

authors： Donaldson GC,Hurst JR,Smith CJ,Hubbard RB,Wedzicha JA

更新日期：2010-05-01 00:00:00

abstract：:To evaluate the role of inhaled ipratropium bromide alone vs oral theophylline plus inhaled beta-agonist or the combination of all three in patients with stable COPD, the following double-blind, placebo-controlled study was conducted. Forty-eight patients with stable COPD (mean age, 61.8 years, with mean baseline FEV1...

journal_title：Chest

authors： Karpel JP,Kotch A,Zinny M,Pesin J,Alleyne W

更新日期：1994-04-01 00:00:00

abstract：:Arrhythmias that may accompany myocardial reperfusion have generated significant clinical interest. First, there were concerns, based on animal studies, that high-grade ventricular tachyarrhythmias would pose a serious threat following thrombolytic therapy to treat an evolving myocardial infarction. Second, lower-grad...

journal_title：Chest

authors： Krumholz HM,Goldberger AL

更新日期：1991-04-01 00:00:00