Renal osteodystrophy, phosphate homeostasis, and vascular calcification.

abstract：:It has been nearly 100 years since the first published report of advanced glycation end products (AGEs) by the French chemist Maillard. Since then, our understanding of AGEs in diseased states has dramatically changed. Especially in the last 25 years, AGEs have been implicated in complications related to aging, neurod...

journal_title：Seminars in dialysis

authors： Mallipattu SK,He JC,Uribarri J

更新日期：2012-09-01 00:00:00

abstract：:Elderly ESRD patients often lose functionality when they start dialysis, which may be due to a variety of clinical problems. We recently postulated that intensive (longer and/or more frequent) hemodialysis (HD) may be the ideal strategy to try to prevent these ESRD- and dialysis-related complications, including dialys...

journal_title：Seminars in dialysis

authors： Cornelis T,Kotanko P,Goffin E,van der Sande FM,Kooman JP,Chan CT

更新日期：2012-11-01 00:00:00

abstract：:There is clear evidence that survival rates following transplantation far exceed those for remaining on dialysis, regardless of body size measured by body mass index (BMI). Studies over the past 15 years also suggest little to no difference in long-term outcomes, including graft survival and mortality, irrespective of...

journal_title：Seminars in dialysis

authors： MacLaughlin HL,Campbell KL

更新日期：2019-05-01 00:00:00

abstract：:Dialysis remains the predominant form of renal replacement therapy in the United States, but the optimal timing for the initiation of dialysis remains poorly defined. Not only clinical factors such as signs/symptoms of uremia, co-existing cardiovascular disease, and presence of diabetes but also key demographic charac...

journal_title：Seminars in dialysis

authors： Streja E,Nicholas SB,Norris KC

更新日期：2013-11-01 00:00:00

abstract：:Growing evidence has been gathered over the last 15 years regarding the role of nontraditional or uremia-related risk factors in the pathogenesis of atherosclerosis in subjects with renal failure. Among those factors, dyslipidemia, inflammation, hyperhomocysteinemia, and oxidant stress have been extensively studied. H...

journal_title：Seminars in dialysis

authors： Madore F

更新日期：2003-03-01 00:00:00

abstract：:Renal osteodystrophy (ROD) is a bone disorder that occurs in chronic kidney disease (CKD) patients and is associated with 2- to 14-fold increased fracture risk compared to the general population. Risk of fractures is also increased in kidney transplant recipients especially within the first 5 years after transplantati...

journal_title：Seminars in dialysis

authors： Babayev R,Nickolas TL

更新日期：2015-11-01 00:00:00

abstract：:Home dialysis (home HD or home PD) remains underutilized in most jurisdictions. Physicians, advanced-practice nurses, and policy makers working with chronic kidney disease populations can provide insights into patient, healthcare professional, and system-level barriers to home dialysis selection by suitable patients. ...

journal_title：Seminars in dialysis

authors： Osterlund K,Mendelssohn D,Clase C,Guyatt G,Nesrallah G

更新日期：2014-03-01 00:00:00

abstract：:Catheter recirculation (CR) occurs when blood returning from the venous limb of the catheter re-enters the arterial limb of the catheter without passage through the circulation. Adequacy of dialysis is influenced by the degree of access recirculation. In this study we evaluate factors influencing the degree of dialysi...

journal_title：Seminars in dialysis

authors： Moossavi S,Vachharajani TJ,Jordan J,Russell GB,Kaufman T,Moossavi S

更新日期：2008-05-01 00:00:00

abstract：:The etiology and management of intradialytic hypotension has become an increasingly complex issue. Volume depletion due to ultrafiltration remains the predominant underlying etiologic factor. However, patients vary markedly in their hemodynamic tolerance to fluid removal. While many risk factors have been identified, ...

journal_title：Seminars in dialysis

authors： Sherman RA

更新日期：2002-05-01 00:00:00

abstract：:In healthy individuals, vitamin D produced in the skin or derived from nutritional sources is converted to 25-hydroxyvitamin D (25[OH]D) in the liver, and then 1,25-dihydroxyvitamin D (1,25[OH](2)D) by 1 alpha-hydroxylase in the kidney. Chronic kidney disease (CKD) is accompanied by a progressive decline in the abilit...

journal_title：Seminars in dialysis

authors： Bhan I,Hewison M,Thadhani R

更新日期：2010-07-01 00:00:00

abstract：:In an attempt to improve patient outcomes in peritoneal dialysis (PD), national organizations (such as the National Kidney Foundation Dialysis Outcomes Quality Initiative [NKF-DOQI] process) have formulated clinical practice guidelines based on clinical evidence available at the time of development. For "adequacy" of ...

journal_title：Seminars in dialysis

authors： Burkart JM

更新日期：2003-01-01 00:00:00

abstract：:Patients with end-stage renal disease are more likely to suffer from gastrointestinal (GI) problems, including bleeding from upper and lower sources. Peptic ulcer disease is the most common cause of upper GI bleeding, and although there is some debate in the literature regarding whether the frequency of ulcer disease ...

journal_title：Seminars in dialysis

authors： Kalman RS,Pedrosa MC

更新日期：2015-01-01 00:00:00

abstract：:Mounting evidence supports a strong association between fluid management and outcomes among individuals receiving maintenance hemodialysis. The speed of fluid removal during dialysis (ultrafiltration, UF) is a modifiable aspect of fluid management that has attracted recent attention as a potential performance measure ...

journal_title：Seminars in dialysis

authors： Flythe JE

更新日期：2016-11-01 00:00:00

abstract：:Until the discovery of calcimimetics, the management of secondary hyperparathyroidism (SHPT) relied exclusively on treatment with phosphate binders, vitamin D derivatives or surgical parathyroidectomy with limited success. The therapeutic use of calcimimetic agents, together with a better understanding of the pivotal ...

journal_title：Seminars in dialysis

authors： Rodríguez M,Goodman WG,Liakopoulos V,Messa P,Wiecek A,Cunningham J

更新日期：2015-09-01 00:00:00

abstract：:Over the last 10 years an increasing number of patients worldwide have started dialysis or had transplantation. Many are elderly with complex comorbid conditions. Registries across the world all show a rapid and dramatic increase in the number of older patients accepted for renal replacement therapy. In addition, the ...

journal_title：Seminars in dialysis

authors： Krishnan M,Lok CE,Jassal SV

更新日期：2002-03-01 00:00:00

abstract：INTRODUCTION:Protein-energy wasting (PEW) is common in hemodialysis patients and is linked with a high rate of morbidity and mortality. Regarding importance of nutrition in these patients, a recent study was administered to evaluate the nutritional status of hemodialysis patients. MATERIALS:In this cross-sectional stu...

journal_title：Seminars in dialysis

authors： Akhlaghi Z,Sharifipour F,Nematy M,Safarian M,Malekahmadi M,Barkhidarian B,Norouzy A

更新日期：2020-10-14 00:00:00

abstract：:Hypertension among patients on hemodialysis is common, difficult to diagnose and often inadequately controlled. Although specific blood pressure (BP) targets in this particular population are not yet established, meta-analyses of randomized trials showed that deliberate BP-lowering with antihypertensive drugs improves...

journal_title：Seminars in dialysis

authors： Georgianos PI,Agarwal R

更新日期：2018-11-01 00:00:00

abstract：:Hyperkalemia is common in patients with end-stage renal disease, and may result in serious electrocardiographic abnormalities. Dialysis is the definitive treatment of hyperkalemia in these patients. Intravenous calcium is used to stabilize the myocardium. Intravenous insulin and nebulized albuterol lower serum potassi...

journal_title：Seminars in dialysis

authors： Putcha N,Allon M

更新日期：2007-09-01 00:00:00

abstract：:Cardiac hypertrophy is a relatively common complication seen in patients with advanced chronic kidney disease (CKD) and end-stage renal disease (ESRD). Moreover, cardiac hypertrophy is even more frequently seen in patients with ESRD who have an arteriovenous (AV) access. There has been substantial evidence pertaining ...

journal_title：Seminars in dialysis

authors： Duque JC,Gomez C,Tabbara M,Alfonso CE,Li X,Vazquez-Padron RI,Asif A,Lenz O,Briones PL,Salman LH

更新日期：2015-05-01 00:00:00

abstract：:Intravenous iron is an important component of the treatment of anemia of end-stage renal disease (ESRD), but it is biologically plausible that iron could increase the risk of infection through impairment of neutrophil and T-cell function and promotion of microbial growth. Any such increase in risk would be particularl...

journal_title：Seminars in dialysis

authors： Ishida JH,Johansen KL

更新日期：2014-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is a common and devastating disease, affecting up to 19.3 million Americans. It is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) in the United States. Diabetic patients with ESRD have a high incidence of cardiovascular disease and death. For those kidney tr...

journal_title：Seminars in dialysis

authors： Luan FL,Samaniego M

更新日期：2010-03-01 00:00:00

abstract：:Over 60% of patients initiating chronic hemodialysis in the United States have a chronic central venous catheter (CVC) as their first blood access device. Although it would be better if these patients started dialysis with fistulas, the CVC is used because it is a reliable and relatively safe method for obtaining bloo...

journal_title：Seminars in dialysis

authors： Ash SR

更新日期：2007-05-01 00:00:00

abstract：:Arteriovenous fistulas (AVFs) and arteriovenous grafts (AVGs) are the vascular accesses of choice for long-term hemodialysis. Strategies to establish and maintain functioning AVFs and AVGs are essential. In addition to clinical evaluation, ultrasound plays a critical role in the evaluation and maintenance of AVFs and ...

journal_title：Seminars in dialysis

authors： Pietryga JA,Little MD,Robbin ML

更新日期：2017-07-01 00:00:00

abstract：:Malnutrition is a frequent complication in hemodialysis patients and is associated with increased mortality and morbidity. Interventions such as oral or intravenous nutritional supplements have often failed to improve nutritional status. We report here the effect that daily dialysis, practiced in our center since 1997...

journal_title：Seminars in dialysis

authors： Galland R,Traeger J

更新日期：2004-03-01 00:00:00

abstract：:The specialty of Nephrology, by virtue of its relationship with the dialysis procedure, is highly vulnerable to litigation. As is the case with all nephrologists, a dialysis unit medical director is not immune to medical malpractice suits, and can be held liable for any act of perceived or potential harm to any dialys...

journal_title：Seminars in dialysis

authors： Vaqar S,Murray B,Panesar M

更新日期：2014-09-01 00:00:00

abstract：:Pregnancy occurs uncommonly in women with chronic kidney disease (CKD) and fetal outcome tends to be poor, with high rates of prematurity and mortality. Dialysis, by complementing residual renal function, may improve fetal outcome in pregnant women with CKD. Although there are no prospective or randomized trials that ...

journal_title：Seminars in dialysis

authors： Shemin D

更新日期：2003-09-01 00:00:00

abstract：:Catheter malfunction due to poor flow is a common problem. When it occurs early, the cause is generally technical. Late occurrences are most often related to thrombus formation. Several types of thrombus may be seen, differing by location and supposed mechanism of formation. The most common offender, however, is the f...

journal_title：Seminars in dialysis

authors： Beathard GA

更新日期：2001-11-01 00:00:00

abstract：:Continuous renal replacement therapy (CRRT) is commonly used in critically ill patients with acute kidney injury. Many studies show that compared with intermittent hemodialysis, continuous therapy has superior hemodynamic stability, metabolic clearance, and volume control. Despite these benefits, no survival advantage...

journal_title：Seminars in dialysis

authors： Finkel KW,Podoll AS

更新日期：2009-03-01 00:00:00

abstract：:Calciphylaxis, a disorder of dermal arteriolar calcification with a distinct predilection for patients with advanced kidney disease, remains an enigmatic condition that challenges clinicians. Observations regarding positive associations between levels of circulating parathyroid hormone (PTH) and the risk of calciphyla...

journal_title：Seminars in dialysis

authors： Nigwekar SU,Sprague SM

更新日期：2016-07-01 00:00:00

abstract：:There has been a dramatic, worldwide expansion in life expectancy across the last century. This has resulted in a progressively more elderly and comorbid population. It is increasingly recognized that healthcare in this group needs to move to the concept of "adding life to years". Recognition and assessment of frailty...

journal_title：Seminars in dialysis

authors： Corbett RW,Brown EA

更新日期：2018-11-01 00:00:00