Iron and infection in hemodialysis patients.

Abstract:

:Intravenous iron is an important component of the treatment of anemia of end-stage renal disease (ESRD), but it is biologically plausible that iron could increase the risk of infection through impairment of neutrophil and T-cell function and promotion of microbial growth. Any such increase in risk would be particularly important because infection is a significant cause of mortality and morbidity in dialysis patients. The overall evidence favors an association between iron and infection in hemodialysis patients, but the optimal iron management strategy to minimize infection risk has yet to be identified. There is a need for further research on this topic, particularly in light of increased utilization of intravenous iron following implementation of the bundled ESRD reimbursement system.

journal_name

Semin Dial

journal_title

Seminars in dialysis

authors

Ishida JH,Johansen KL

doi

10.1111/sdi.12168

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

26-36

issue

1

eissn

0894-0959

issn

1525-139X

journal_volume

27

pub_type

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